检索结果-南通市图书馆

Journal of zhejiang university-Science A(Applied Physics & Engineering) 2008年第7期9卷 940-943页

作者： Yong LI Fan DING jian cui qi-peng LI state key laboratory of Fluid Power Transmission and Control Zhejiang University Hangzhou 310027 China School of Mechanical and Automobile Engineering Zhejiang University of Science and Technology Hangzhou 310023 China

This paper presents a bi-directional permanent-magnet linear actuator for directly driving electrohydraulic valves with low power consumption. Its static and dynamic performances were analyzed using the 2D finite element method,taking into account the nonlinear characterization and the eddy current loss of the magnetic material. The experiment and simulation results agree well and show that the prototype actuator can produce a force of ±100 N with the maximum power being 7 W and has linear characteristics with a positive magnetic stiffness within a stroke of ±1 mm. Its non-linearity is less than 1.5% and the hysteresis less than 1.5%. The actuator's frequency response(-3 dB) of the displacement reaches about 15 Hz,and the most significant factor affecting the dynamic performance is identified as the eddy current loss of the magnetic material.

关键词： Electrohydraulic valves Linear actuator Low power High pressure Positive magnetic stiffness

ART1 and putrescine contribute to rice aluminum resistance via OsMYB30 in cell wall modification

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2023年第4期65卷 934-949页

作者： Li Jun Gao Xiang Pei Liu Ke Ke Gao Meng qi cui Hui Hui Zhu Gui Xin Li Jing Ying Yan Yun Rong Wu Zhong Jie Ding Xue Wei Chen jian Feng Ma Nicholas PHarberd Shao jian Zheng state key laboratory of Plant Physiology and Biochemistry College of Life SciencesZhejiang UniversityHangzhou 310058China Guangdong laboratory for Lingnan Modern Agriculture College of Natural Resources and EnvironmentSouth China Agricultural UniversityGuangzhou 5100642China Shenzhen Branch Guangdong Laboratory of Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518120China College of Agronomy and Biotechnology Zhejiang UniversityHangzhou 310058China Agricultural Experimental Station Zhejiang UniversityHangzhou 310058China Rice Research Institute Sichuan Agricultural University at WenjiangChengdu 611130China Institute of Plant Science and Resources Okayama UniversityKurashiki 710‐0046Japan Department of Plant Science University of OxfordOxford OX13RBUnited Kingdom

Cell wall is the first physical barrier to aluminum(Al)*** of cell wall properties to change its binding capacity to Al is one of the major strategies for plant Al resistance;nevertheless,how it is regulated in rice remains largely *** this study,we show that exogenous application of putrescines(Put)could significantly restore the Al resistance of art1,a rice mutant lacking the central regulator Al RESISTANCE TRANSCRIPTION FACTOR 1(ART1),and reduce its Al accumulation particularly in the cell wall of root *** on RNA-sequencing,yeast-onehybrid and electrophoresis mobility shift assays,we identified an R2R3 MYB transcription factor OsMYB30 as the novel target in both ART1-dependent and Put-promoted Al ***,transient dual-luciferase assay showed that ART1 directly inhibited the expression of OsMYB30,and in turn repressed Os4CL5-dependent 4-coumaric acid accumulation,hence reducing the Al-binding capacity of cell wall and enhancing Al ***,Put repressed OsMYB30 expression by eliminating Alinduced H2O2accumulation,while exogenous H2O2promoted OsMYB30 *** concluded that ART1 confers Put-promoted Al resistance via repression of OsMYB30-regulated modification of cell wall properties in rice.

关键词： ART1 cell wall 4‐coumaric acid OsMYB30 Os4CL5 putrescine

Analysis of Health Service Utilization and its Influencing Factors among Patients with Pneumoconiosis in china

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2021年第1期34卷 83-88页

作者： WANG Huan qiang JIA Jun Lin jianG Zhao qiang JIN qi LI Dong Xia LING Rui Jie LI Ying cui Ping CHEN Gang ZHAO Hong Yu LI Yan WEN Ke LYU Xiang Pei LOU jian Lin LI Tao National Institute of Occupational Health and Poison Control Chinese Center for Disease Control and PreventionBeijing 100050China hangzhou Medical College(Zhejia ng Academy of Medical Sciences) Hangzhou 310013ZhejiangChina Center for Clinical Big Data and Analytics The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009ZhejiangChina Guizhou Hospital for Occupational Disease Prevention and Control Guiyang 550006GuizhouChina Hubei Hospital for Occupational Diseases Wuhan 430000HubeiChina Hunan Prevention and Treatment Center for Occupational Disease Changsha 410007HunanChina Shandong Academy of Occupational Health and Occupational Medicine Jinan 250062ShandongChina Beidaihe Hospital for Occupational Disease Prevent on and ControlState Administration of Production SafetyQinhuangdao 066100HebeiChina Yunnan Hospital for Occupational Diseases Kunming 650011YunnanChina Jilin Hospital for Occupational Disease Prevention and Control Changchun 132000JilinChina

Pneumoconiosis,an interstitial lung disease that occurs from breathing in certain kinds of damaging dust particles,is a major occupational disease in *** diagnosed with occupational pneumoconiosis can avail of free medical treatment,whereas patients without a diagnosis of occupational diseases cannot not claim free medical treatment in most provinces from the government before *** study aimed to analyze the priority of medical facility selection and its influencing factors among patients with pneumoconiosis.

关键词： diagnosis treatment among

A transcription factor STOP1-centered pathway coordinates ammonium and phosphate acquisition in Arabidopsis

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2021年第9期14卷 1554-1568页

作者： Wen Hao Tian Jia Yuan Ye Meng qi cui Jun Bo Chang Yu Liu GuiXin Li Yun Rong Wu Ji Ming Xu Nicholas P.Harberd Chuan Zao Mao Chong Wei Jin Zhong Jie Ding Shao jian Zheng state key laboratory of Plant Physiology and Biochemistry College of Life ScienceZhejiang UniversityHangzhou 310058China College of Environmental and Resource Sciences Zhejiang UniversityHangzhou 310038China College of Agronomy and Biotechnology Zhejiang UniversityHangzhou 310038China Department of Plant Sciences University of OxfordOxford OX13RBUK Guangdong laboratory for Lingnan Modern Agriculture College of Natural Resources and EnvironmentSouth China Agricultural UniversityGuangzhou 5100642China

Phosphorus(P)is an indispensable macronutrient required for plant growth and *** phosphate(Pi)reserves are finite,and a better understanding of Pi utilization by crops is therefore vital for worldwide food *** has long been known to enhance Pi acquisition efficiency in agriculture;however,the molecular mechanisms coordinating Pi nutrition and ammonium remains ***,we reveal that ammonium is a novel initiator that stimulates the accumulation of a key regulatory protein,STOP1,in the nuclei of Arabidopsis root cells under Pi *** show that Pi deficiency promotes ammonium uptake mediated by AMT1 transporters and causes rapid acidification of the root *** acidification-triggered STOP1 accumulation activates the excretion of organic acids,which help to solubilize Pi from insoluble iron or calcium *** uptake by AMT1 transporters is downregulated by a CIPK23 protein kinase whose expression is directly modulated by STOP1 when ammonium reaches toxic *** together,we have identified a STOP1-centered regulatory network that links external ammonium with efficient Pi acquisition from insoluble phosphate *** findings provide a framework for developing possible strategies to improve crop production by enhancing the utilization of non-bioavailable nutrients in soil.

关键词： Pi deficiency response ammonium STOP1 organic acid exudation CIPK23

Expert consensus on the monitoring and treatment of sepsis-induced immunosuppression

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Military Medical Research 2023年第3期10卷 281-298页

作者： Fei Pei Ren‑qi Yao Chao Ren Soheyl Bahrami Timothy RBilliar Irshad HChaudry De‑Chang Chen Xu‑Lin Chen Na cui Xiang‑Ming Fang Yan Kang Wei‑qin Li Wen‑Xiong Li Hua‑Ping Liang Hong‑Yuan Lin Ke‑Xuan Liu Ben Lu Zhong‑qiu Lu Marc Maegele Tian‑qing Peng You Shang Lei Su Bing‑Wei Sun Chang‑Song Wang jian Wang jiang‑Huai Wang Ping Wang jian‑Feng Xie Li‑Xin Xie Li‑Na Zhang Basilia Zingarelli Xiang‑Dong Guan jian‑Feng Wu Yong‑Ming Yao Department of Critical Care Medicine the First Affiliated Hospital of Sun Yat-Sen University58 Zhongshan Er RoadYuexiu DistrictGuangzhou 510080GuangdongChina Translational Medicine Research Center Medical Innovation Research Division and Fourth Medical Center of the Chinese PLA General Hospital28 Fuxing RoadHaidian DistrictBeijing 100853China Department of Burn Surgery the First Affiliated Hospital of Naval Medical UniversityShanghai 200433China Ludwig-Boltzmann Institute for Experimental and Clinical Traumatology 1200 ViennaAustria Department of Surgery University of Pittsburgh Medical CenterPittsburghPA 15213USA Center for Surgical Research and Department of Surgery University of Alabama at BirminghamBirminghamAL 35294USA Department of Critical Care Medicine Ruijin HospitalShanghai Jiaotong UniversityShanghai 200025China Department of Burns the First Affiliated Hospital of Anhui Medical UniversityHefei 230022China Department of Critical Care Medicine Peking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100730China Department of Anesthesiology the First Affiliated HospitalZhejiang University School of MedicineHangzhou 31003China Department of Critical Care Medicine West China Hospital of Sichuan UniversityChengdu 610041China Department of Critical Care Medicine General Hospital of Eastern Theater Command of Chinese PLANanjing 210002China Department of Surgical Intensive Critical Unit Beijing Chao‑Yang HospitalCapital Medical UniversityBeijing 100020China state key laboratory of Trauma Burns and Combined InjuryResearch Institute of SurgeryDaping HospitalArmy Medical UniversityChongqing 400042China Department of Critical Care Medicine Fourth Medical Center of the Chinese PLA General HospitalBeijing 100048China Department of Anesthesiology Nanfang HospitalSouthern Medical UniversityGuangzhou 510515China Department of Critical Care Medicine and Hematology the Third Xiangya HospitalCentral South UniversityChangs

Emerged evidence has indicated that immunosuppression is involved in the occurrence and development of *** provide clinical practice recommendations on the immune function in sepsis,an expert consensus focusing on the monitoring and treatment of sepsis-induced immunosuppression was *** related to the immune monitoring and treatment of sepsis were retrieved from PubMed,Web of Science,and Chinese National Knowledge Infrastructure to design items and expert opinions were collected through an online ***,the Delphi method was used to form consensus opinions,and RAND appropriateness method was developed to provide consistency evaluation and recommendation levels for consensus *** consensus achieved satisfactory results through two rounds of questionnaire survey,with 2 statements rated as perfect consistency,13 as very good consistency,and 9 as good *** summarizing the results,a total of 14 strong recommended opinions,8 weak recommended opinions and 2 non-recommended opinions were ***,a face-to-face discussion of the consensus opinions was performed through an online meeting,and all judges unanimously agreed on the content of this *** summary,this expert consensus provides a preliminary guidance for the monitoring and treatment of immunosuppression in patients with sepsis.

关键词： Sepsis Immune function monitoring Immunomodulatory therapy Immunosuppression

Biomedical polymers: synthesis, properties, and applications

在线全文

学校读者我要写书评

暂无评论

Science china Chemistry 2022年第6期65卷 1010-1075页

作者： Wei-Hai Chen qi-Wen Chen qian Chen Chunyan cui Shun Duan Yongyuan Kang Yang Liu Yun Liu Wali Muhammad Shiqun Shao Chengqiang Tang Jinqiang Wang Lei Wang Meng-Hua Xiong Lichen Yin Kuo Zhang Zhanzhan Zhang Xu Zhen Jun Feng Changyou Gao Zhen Gu Chaoliang He jian Ji Xiqun jiang Wenguang Liu Zhuang Liu Huisheng Peng Youqing Shen Linqi Shi Xuemei Sun Hao Wang Jun Wang Haihua Xiao Fu-jian Xu Zhiyuan Zhong Xian-Zheng Zhang Xuesi Chen key laboratory of Biomedical Polymers of Ministry of Education&Department of Chemistry Wuhan UniversityWuhan430072China Institute of Functional Nano&Soft Materials(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials&DevicesSoochow UniversitySuzhou215123China School of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional MaterialsTianjin UniversityTianjin300350China key laboratory of Biomedical Materials of Natural Macromolecules(Beijing university of Chemical Technology) Ministry of EducationBeijing Laboratory of Biomedical MaterialsCollege of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing100029China MOE key laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou310027China state key laboratory of Medicinal Chemical Biology Key Laboratory of Functional Polymer Materials of Ministry of EducationCollege of ChemistryNankai UniversityTianjin300071China key laboratory of Advanced Drug Delivery Systems of zhejiang Province College of Pharmaceutical SciencesZhejiang UniversityHangzhou310058China Jinhua Institute of zhejiang university Jinhua321299China zhejiang key laboratory of Smart BioMaterials and Center for Bionanoengineering College of Chemical and Biological EngineeringZhejiang UniversityHangzhou310027China ZJU-hangzhou Global Scientific and Technological Innovation Center Hangzhou311215China state key laboratory of Molecular Engineering of Polymers Department of Macromolecular Science and Laboratory of Advanced MaterialsFudan UniversityShanghai200438China CAS key laboratory for Biomedical Effects of Nanomaterials and Nanosafety CAS Center for Excellence in Nano-scienceNational Center for Nanoscience and Technology(NCNST)Beijing100190China School of Biomedical Sciences and Engineering Guangzhou International CampusSouth China University of TechnologyGuangzhou510006China Institute of Functional Nano and So

Biomedical polymers have been extensively developed for promising applications in a lot of biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis, biosensing, regenerative medicine, and disease treatment. In this review, we summarize the most recent advances in the synthesis and application of biomedical polymers, and discuss the comprehensive understanding of their property-function relationship for corresponding biomedical applications. In particular, a few burgeoning bioactive polymers, such as peptide/biomembrane/microorganism/cell-based biomedical polymers, are also introduced and highlighted as the emerging biomaterials for cancer precision therapy. Furthermore, the foreseeable challenges and outlook of the development of more efficient, healthier and safer biomedical polymers are discussed. We wish this systemic and comprehensive review on highlighting frontier progress of biomedical polymers could inspire and promote new breakthrough in fundamental research and clinical translation.

关键词： biomedical polymer nanomedicine cancer therapy drug delivery bioimaging and biosensing tissue engineering regenerative medicine cytotoxicity biocompatibility

在线全文

学校读者我要写书评

暂无评论

基于功率谱密度的评估岩石节理粗糙度新方法

岩土力学 2022年第11期43卷 3135-3143页

作者：张传庆郭宇航徐金顺刘宁谢起明崔国建周辉中国科学院武汉岩土力学研究所岩土力学与工程国家重点实验室湖北武汉430071 中国科学院大学北京100049 雅砻江流域水电开发有限公司四川成都610051 中国电建集团华东勘测设计研究院有限公司浙江杭州310014

为进一步提高结构面粗糙特征描述的精确性和可靠性,更全面地体现出细微形貌的影响,将轮廓线凹凸起伏分解为幅值、倾角和曲率3个特征,分别代表轮廓线的高度变化、角度变化和弯曲程度变化。以Barton建议的10条标准轮廓线为例,计算其幅度... 详细信息

为进一步提高结构面粗糙特征描述的精确性和可靠性,更全面地体现出细微形貌的影响,将轮廓线凹凸起伏分解为幅值、倾角和曲率3个特征,分别代表轮廓线的高度变化、角度变化和弯曲程度变化。以Barton建议的10条标准轮廓线为例,计算其幅度、角度和弯曲度的特征曲线,获得了三者的分布规律。利用可表征微细观形貌的功率谱密度函数研究了3种特征曲线的频谱特征,然后从功率谱密度对数曲线中提取了可以描述形貌特征的分形参数D_(j)(斜率相关)和粗糙度参数Aj(截距相关),在此基础上研究了D_(j)和A_(j)与节理粗糙度系数(joint roughness coefficient,简称JRC)的关系。同时,将该指标推广到了三维形貌的表征形式,并计算了大理岩剪切面的三维粗糙度。结果表明:新指标评估精确度高,可反映结构面各向异性特征,能有效表征结构面粗糙特征,对研究结构面剪切力学性质有重要意义。

关键词：岩体结构面粗糙度表征功率谱密度曲率

Chinese Medical Association consensus for standardized diagnosis and treatment of pancreatic neuroendocrine neoplasms

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2023年第20期136卷 2397-2411页

作者： Feng Jiao Jiujie cui Deliang Fu qi Li Zheng Wu Zan Teng Hongmei Zhang Jun Zhou Zhihong Zhang Xiaobing Chen Yuhong Zhou Yixiong Li Yiping Mou Renyi qin Yongwei Sun Gang Jin Yuejuan Cheng jian Wang Gang Ren jiang Yue Guangxin Jin Xiuying Xiao Liwei Wang on behalf of Pancreatic Tumor Group,Society of Oncology,Chinese Medical Association Department of Oncology State Key Laboratory of Systems Medicine for CancerShanghai Cancer InstituteRenji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Department of Pancreatic Surgery Huashan HospitalFudan UniversityShanghai 200040China Department of Oncology Shanghai General HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200080China Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiao Tong UniversityXi’anShaanxi 710061China Department of Oncology The First Hospital of China Medical UniversityShenyangLiaoning 110801China Department of Medical Oncology The First Affiliated Hospital of Air Force Medical UniversityXi’anShaanxi 710032China Department of Gastrointestinal Oncology Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing)Peking University Cancer Hospital and InstituteBeijing 100142China Department of Pathology The First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu 210029China Department of Oncology The Affiliated Cancer Hospital of Zhengzhou UniversityHenan Cancer HospitalZhengzhouHenan 450003China Department of Medical Oncology Zhongshan HospitalFudan UniversityShanghai 200032China Department of General Surgery Xiangya HospitalCentral South UniversityChangshaHunan 410008China Department of Gastrointestinal and Pancreatic Surgery Zhejiang Provincial People’s HospitalAffiliated People’s HospitalHangzhou Medical CollegeHangzhouZhejiang 310014China Department of Biliary-Pancreatic Surgery Affiliated Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030China Department of Biliary-Pancreatic Surgery Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Department of Hepatobiliary Pancreatic Surgery Changhai HospitalNaval Medical UniversityShanghai 200433China Department of Medical Oncology Peking Union Medical College HospitalChinese Academy of Medical Sci

Pancreatic neuroendocrine neoplasms(pNENs)are rare and highly heterogeneous tumors originating from pluripotent stem cells with neuroendocrine differentiation in the pancreas,constituting approximately 3%of all pancreatic tumors.^([1])The global incidence of pNENs has been increasing recently,and most cases are sporadic and more common in women.^([1,2])pNENs are clinically divided into functioning and nonfunctioning tumors depending on whether the tumors are accompanied by a clinical syndrome related to specific hormone overproduction.

关键词： neoplasms neuroendocrine diagnosis

CEPC Technical Design Report

在线全文

学校读者我要写书评

暂无评论

Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua cui Xiaohao cui Zhaoyuan cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong jianin AGH university of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui university HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu university Institute of ScienceVaranasi Bandirma Onyedi Eylul university Bandirma Beihang university Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal university Beijing Brown university ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk cadi Ayyad university Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo university Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central china Normal university WuhanHubei Central South university ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan china academy of engineering physics MianyangSichuan china building materials academy Beijing china Center of Advanced Science and Technology Beijing china Institute of Atomic Energy Beijing china Jiliang university HangzhouZhejiang china Nuclear Instrument CO. LTDBeijing china university of Geosciences Beijing china university of Geosciences WuhanHubei china university of Mining and Technology XuzhouJiangsu china West Normal university NanchongSichuan Chongqing university Department of PhysicsChongqing Chulalongkorn university Bangkok City university of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell university IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu university DalianLiaoning Dalian university of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East china university Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise