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Metastable face-centered cubic ruthenium-based binary alloy for efficient alkaline hydrogen oxidation electrocatalysis

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Journal of Energy Chemistry 2024年第5期92卷 207-215页

作者： Yunbo Li Jianchao Yue Chaoyi Yang Hongnan Jia Hengjiang cong Wei Luo College of Chemistry and Molecular Sciences Wuhan UniversityWuhan 430072HubeiChina

Metastable nanostructured electrocatalyst with a completely different surface environment compared to conventional phase-based electrocatalyst often shows distinctive catalytic *** Ru-based electrocatalysts have been widely investigated toward hydrogen oxidation reaction(HOR)under alkaline electrolytes,these studies are mostly limited to conventional hexagonal-close-packed(hcp)phase,mainly arising from the lack of sufficient synthesis *** this study,we report the precise synthesis of metastable binary RuW alloy with face-centered-cubic(fcc)*** find that the introduction of W can serve as fcc phase seeds and reduce the formation energy of metastable fcc-RuW ***,fcc-RuW exhibits remarkable alkaline HOR performance and stability with the activity of 0.67 mA cm_(Ru)^(-2)which is almost five and three times higher than that of hcp-Ru and commercial Pt/C,respectively,which is attributed to the optimized binding strength of adsorbed hydroxide intermediate derived from tailored electronic structure through W doping and phase ***,this strategy can also be applied to synthesize other metastable fcc-RuCr and fcc-RuMo alloys with enhanced HOR performances.

关键词： Hydrogen oxidation reaction Metastable phase Face-centered cubic(fcc) Ru Phase engineering

Oral peptide therapeutics for diabetes treatment: State-of-the-art and future perspectives

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Acta Pharmaceutica Sinica B 2024年第5期14卷 2006-2025页

作者： Bingwen Ding Zhu Zhu cong Guo Jiaxin Li Yong Gan Miaorong Yu State Key Laboratory of Drug Research and Center of Pharmaceutics Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beijing 100049China School of Pharmacy Henan UniversityKaifeng 475004China NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients National Institutes for Food and Drug ControlBeijing 100050China

Diabetes,characterized by hyperglycemia,is a major cause of death and disability ***,such as insulin and glucagon-like peptide-1(GLP-1)analogs,have shown promise as treatments for diabetes due to their ability to mimic or enhance insulin's actions in the *** to subcutaneous injection,oral administration of anti-diabetic peptides is a preferred ***,biological barriers significantly reduce the efficacy of oral peptide *** advancements in drug delivery systems and formulation techniques have greatly improved the oral delivery of peptide therapeutics and their efficacy in treating *** review will highlight(1)the benefits of oral anti-diabetic peptide therapeutics;(2)the biological barriers for oral peptide delivery,including pH and enzyme degradation,intestinal mucosa barrier,and biodistribution barrier;(3)the delivery platforms to overcome these biological ***,the review will discuss the prospects in this *** information provided in this review will serve as a valuable guide for future developments in oral anti-diabetic peptide therapeutics.

关键词： Oral peptides Diabetes Delivery platforms Insulin Glucagon-like peptide-1 Biodistribution Biological barriers Targeted delivery

Optical manipulation of ratio-designable Janus microspheres

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Photonics Research 2024年第6期12卷 1239-1249页

作者： YULU CHEN cong ZHAI XIAOQING GAO HAN WANG ZUZENG LIN XIAOWEI ZHOU CHUNGUANG HU State Key Laboratory of Precision Measuring Technology and Instruments Tianjin UniversityTianjin 300072China

Angular optical trapping based on Janus microspheres has been proven to be a novel method to achieve controllable *** contrast to natural birefringent crystals,Janus microspheres are chemically synthesized of two compositions with different refractive ***,their structures can be artificially regulated,which brings excellent potential for fine and multi-degree-of-freedom manipulation in the optical ***,it is a considerable challenge to model the interaction of heterogeneous particles with the optical field,and there has also been no experimental study on the optical manipulation of microspheres with such designable refractive index *** the specific structure affects the kinematic properties of Janus microspheres remains ***,we report systematic research on the optical trapping and rotating of various ratio-designable Janus *** employ an efficient T-matrix method to rapidly calculate the optical force and torque on Janus microspheres to obtain their trapped postures and rotational characteristics in the optical *** have developed a robust microfluidic-based scheme to prepare Janus *** experimental results demonstrate that within a specific ratio range,the rotation radii of microspheres vary linearly and the orientations of microsphere are always aligned with the light polarization *** is of great importance in guiding the design of Janus *** their orientations flip at a particular ratio,all consistent with the *** work provides a reliable theoretical analysis and experimental strategy for studying the interaction of heterogeneous particles with the optical field and further expands the diverse manipulation capabilities of optical tweezers.

关键词： polarization ratio refractive

Graphdiyne oxide substrate-enhanced peroxidase-mimicking performance of Ru nanoparticles with physiological pH preference

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Nano Research 2024年第3期17卷 1123-1131页

作者： cong Xu Wenjie Ma Haozhi Wang Leihou Shao Weiqi Li Ping Yu Lanqun Mao Beijing National Laboratory for Molecular Science Key Laboratory of Analytical Chemistry for Living BiosystemsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory of Marine Resource Utilization in South China Sea School of Materials Science and EngineeringHainan UniversityHaikou 570228China College of Chemistry Beijing Normal UniversityBeijing 100875China

Modulating electronic structure of metal nanoparticles via metal–support interaction has attracted intense interest in the field of catalytic ***,the roles of supporting substrates in regulating catalytic properties of nanozymes remain *** this study,we find that the use of graphdiyne oxide(GDYO)as the substrate for self-terminating growth of Ru nanoparticles(Ru@GDYO)endows the peroxidase-like activity of Ru nanoparticles with intrinsic physiological pH preference and natural horseradish peroxidase(HRP)comparable *** nanoparticles electrolessly deposited onto GDYO possess a partially oxidized electronic structure owing to limited charge transfer between Ru and GDYO,contributing to the intrinsic physiological pH preference of the peroxidase-mimicking *** importantly,the substrate GDYO plays an influential factor in enhancing catalytic activity,that is,the activity of Ru@GDYO is much higher than that of Ru nanoparticles deposited on other carbon substrates including graphene oxides and *** demonstrate the application of Ru@GDYO nanozyme in neutral solutions,we employ Ru@GDYO with nicotinamide adenine dinucleotide(NAD+)-dependent dehydrogenases in physiological conditions to realize a sustainable cascade reaction by means of forming continuous NAD^(+)/dihydronicotiamide adenine dinucleotide(NADH)*** finding represents a promising perspective on designing high-performance peroxidase-mimicking nanozymes with broader applicability,raising fundamental understanding of structure–activity relationship,and investigating new applications of nanozymes in biological systems.

关键词： nanozyme graphdiyne reactive oxygen species electroless deposition metal–support interaction

Optimizing Optical Fiber Faults Detection:A Comparative Analysis of Advanced Machine Learning Approaches

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Computers, Materials & Continua 2024年第5期79卷 2697-2721页

作者： Kamlesh Kumar Soothar Yuanxiang Chen Arif Hussain Magsi cong Hu Hussain Shah School of Electronics Engineering Beijing University of Posts and TelecommunicationsBeijing100876China State Key Laboratory of Integrated Services Networks Xidian UniversityXi’an710071China State Key Laboratory ofNetworking and Switching Technology Beijing University of Posts and TelecommunicationsBeijing100876China

Efficient optical network management poses significant importance in backhaul and access network communicationfor preventing service disruptions and ensuring Quality of Service(QoS)*** emerging faultsin optical networks introduce challenges that can jeopardize the network with a variety of *** existingliterature witnessed various partial or inadequate *** the other hand,Machine Learning(ML)hasrevolutionized as a promising technique for fault detection and *** traditional fault managementsystems,this research has three-fold ***,this research leverages the ML and Deep Learning(DL)multi-classification system and evaluates their accuracy in detecting six distinct fault types,including fiber cut,fibereavesdropping,splicing,bad connector,bending,and PC ***,this paper assesses the classificationdelay of each classification ***,this work proposes a fiber optics fault prevention algorithm thatdetermines to mitigate the faults *** work utilized a publicly available fiber optics dataset namedOTDR_Data and applied different ML classifiers,such as Gaussian Naive Bayes(GNB),Logistic Regression(LR),Support Vector Machine(SVM),K-Nearest Neighbor(KNN),Random Forest(RF),and Decision Tree(DT).Moreover,Ensemble Learning(EL)techniques are applied to evaluate the accuracy of various *** addition,this work evaluated the performance of DL-based Convolutional Neural Network and Long-Short Term Memory(CNN-LSTM)hybrid *** findings reveal that the CNN-LSTM hybrid technique achieved the highestaccuracy of 99%with a delay of 360 *** the other hand,EL techniques improved the accuracy in detecting fiberoptic ***,this research comprehensively assesses accuracy and delay metrics for various classifiers andproposes the most efficient attack detection system in fiber optics.

关键词： Fiber optics fault detection multiclassification machine learning ensemble learning

Analysis on influencing factors of detecting chemical oxygen demand in water by three-dimensional spectroscopy

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Optoelectronics Letters 2024年第1期20卷 42-47页

作者： ZHOU Kunpeng LIU Zhiyang cong Menglong MAN Shanxin Inner Mongolia Autonomous Region Joint Laboratory of Nuclear and Radiation Detection College of Physics and Electronic InformationInner Mongolia Minzu UniversityTongliao 028000China College of Information Engineering Jingzhou UniversityJingzhou 434000China Alxa League Meteorological Bureau Alxa 750300China

This paper focuses on the standard chemical oxygen demand(COD)liquid and studies the impact of pH,nitrite nitrogen,nitrate nitrogen,heavy metals,salinity,and other factors on fluorescence intensity and fluorescence peak positions during the detection of COD in water using fluorescence *** influence mechanisms of different environmental factors on fluorescence spectra are also *** indicate that pH value affects the fluorescence emission wavelength(Em),resulting in a red shift from 1.5 to 7.2,and a blue shift from 7.2 to *** nitrogen can react with organic matter in water to form nitro compounds,leading to a decrease in fluorescence *** has a negligible effect on T1 peak but a relatively large effect on T2 *** metal ion concentration has a significant impact on T2 peak,while T1 peak position shifts with an increase in heavy metal *** study aims to explore the factors that can impact the detection of COD in water using three-dimensional fluorescence spectrometry,providing references to improve accuracy and practicability for COD detection based on three-dimensional fluorescence spectrometry.

关键词： chemical negligible nitrate

Influence of Trailing-Edge Wear on the Vibrational Behavior of Wind Turbine Blades

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Fluid Dynamics & Materials Processing 2024年第2期20卷 337-348页

作者： Yuanjun Dai Xin Wei Baohua Li cong Wang Kunju Shi Mechanical College Shanghai Dian Ji UniversityShanghai201306China College of Energy Engineering Xinjiang Institute of EngineeringUrumqi830091China

To study the impact of the trailing-edge wear on the vibrational behavior of wind-turbine blades,unworn blades and trailing-edge worn blades have been assessed through relevant modal *** to these experiments,the natural frequencies of trailing-edge worn blades-1,-2,and-3 increase the most in the second to fourth order,theﬁfth order increases in the middle,and theﬁrst order increases the *** damping ratio data indi-cate that,in general,theﬁrstﬁve-order damping ratios of trailing-edge worn blades-1 and trailing-edge worn blades-2 are reduced,and theﬁrstﬁve-order damping ratios of trailing-edge worn blades-3 are slightly *** mode shape diagram shows that the trailing-edge worn blades-1 and-2 have a large swing in the tip and the blade,whereas the second-and third-order vibration shapes of the trailing edge-worn blade-3 tend to be ***,all these results reveal that the blade’s mass and the wear area are the main fac-tors affecting the vibration characteristics of wind turbine blades.

关键词： Wind turbine modal test natural frequency damping ratio mode shape

Comparative transcriptome analysis reveals key genes and pathways in response to Alternaria alternata apple pathotype infection

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Horticultural Plant Journal 2024年第3期10卷 641-656页

作者： Kai Liu Zhaolin Liang An Yang Jiadi Yan Peihua cong Xiaolei Han Caixia Zhang Key Laboratory of Horticultural Crop Germplasm Utilization of the Ministry of Agriculture and Rural Affairs(MOA) Research Institute of PomologyChinese Academy of Agricultural SciencesXingchengLiaoning 125100China

Apple leaf spot,caused by the Alternaria alternata apple pathotype(AAAP),is an important fungal disease of *** understand the molecular basis of resistance and pathogenesis in apple leaf spot,the transcriptomes of two apple cultivars‘Hanfu'(HF)(resistant)and‘Golden Delicious'(GD)(susceptible)were analyzed at 0,6,18,24 and 48 h after AAAP inoculation by *** each time point,a large number of significantly differentially expressed genes(DEGs)were screened between AAAP-inoculated and uninoculated apple *** of the common DEGs at four time points revealed significant differences in the resistance of‘HF'and‘GD'apple to AAAP ***,RNL,and JA signal-related genes were upregulated in both cultivars to restrict AAAP ***,genes encoding CNLs,TNLs,WRKYs,and AP2s were only activated in‘HF'as part of the resistance response,of which,some play major roles in the regulation of ET and SA signal *** analysis showed that many DEGs with opposite expression trends in the two hosts may play important regulatory roles in response to AAAP *** expression of one such gene MdERF110 in‘GD'apple leaves improved AAAP ***,this study highlights the reasons for differential resistance to AAAP infection between‘HF'and‘GD'apples which can theoretically assist the molecular breeding of disease-resistant apple crops.

关键词： Apple Transcriptome Alternaria alternata apple pathotype Infection Defense response

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从土壤水动力学到生态水文学的发展与展望

水利学报 2016年第3期47卷 390-397页

作者：杨大文丛振涛尚松浩倪广恒清华大学水利水电工程系北京100084

在20世纪80年代,土壤水动力学成为我国水文水资源领域的一个新兴研究方向。在此后的30多年中,土壤水动力学得到了巨大发展,并对我国农田水利、水文水资源等领域的科学与技术起到了巨大的推动作用。以土壤水动力学为基础,逐步认识了非饱... 详细信息

在20世纪80年代,土壤水动力学成为我国水文水资源领域的一个新兴研究方向。在此后的30多年中,土壤水动力学得到了巨大发展,并对我国农田水利、水文水资源等领域的科学与技术起到了巨大的推动作用。以土壤水动力学为基础,逐步认识了非饱和土壤中水分与热量、溶质等耦合运移机理与规律,在20世纪90年代发展了土壤-作物-大气之间的水热交换和传输理论(即土壤-植物-大气连续体理论,简称SPAC理论)。以SPAC理论为基础,农田作物模型得到了快速发展,成为本世纪研究气候变化对农业水资源和粮食生产影响的主要工具。与此同时,从农田到区域的水转化机理与规律、不同尺度的农业用水效率、以及水资源开发利用的生态和环境影响等基础科学问题和生产实践问题逐渐被重视,从而形成了新的交叉学科——生态水文学。生态水文学以水分-能量-物质耦合循环的动力学过程为基础,注重区域气候-植被/作物-水文相互作用的基础科学问题,旨在为区域水资源、生态和环境评价与管理提供科学依据。

关键词：土壤水动力学土壤-植物-大气连续体水分-能量-物质循环生态水文学