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冶金信息导刊 2024年第1期61卷 46-48,16页

作者：谢聪陈杰翔甘幸张朗铭梁辉广西柳钢中金不锈钢有限公司炼铁厂玉林537624

高炉原燃料含粉率高对高炉冶炼影响大,造成高炉炉况波动,气流分布混乱,不利于中心气流形成。因此降低入炉的含粉量,使高炉炉况正常便于操作,是保证高炉稳定运行,顺产高产的一项重要措施,从而达到降本增效,实现较大的经济效益。

关键词：高炉生产工艺筛分应用

Postoperative adjuvant transcatheter arterial chemoembolization improves the prognosis of patients with huge hepatocellular carcinoma

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Hepatobiliary & Pancreatic Diseases International 2021年第3期20卷 232-239页

作者： Han Wang Hua Yu You-Wen Qian Zhen-Ying Cao Meng-Chao Wu Wen-Ming cong Department of Pathology Eastern Hepatobiliary Surgery HospitalThe Second Military Medical UniversityYangpuShanghai 200438China Department of Hepatic Surgery Eastern Hepatobiliary Surgery HospitalThe Second Military Medical UniversityShanghai 200438China

Background: Surgical resection of huge hepatocellular carcinoma(HCC, ≥ 10 cm) is potentially curative. More adjuvant treatments are needed to reduce relapses in these patients. We evaluated the influence of postoperative adjuvant transcatheter arterial chemoembolization(PA-TACE) on the prognosis of huge HCC. Methods: Data from consecutive patients who underwent curative resection for huge HCC in our center were retrospectively collected. Recurrence-free survival(RFS) and overall survival(OS) were compared between patients who did and did not undergo PA-TACE. Propensity score matching(PSM) was used. Results: Among the 255 enrolled patients, 93 underwent PA-TACE. The clinical outcomes were significantly better in the PA-TACE group than those in the non PA-TACE group(5-year RFS rate: 33.5% vs. 18.0%;5-year OS rate: 47.0% vs. 28.0%, all P<0.001). After PSM, similar results were obtained(5-year RFS rate: 28.8% vs. 17.6%, P<0.001;5-year OS rate: 42.5% vs. 25.0%, P=0.004). PA-TACE decreased the possibility of early recurrence(<2 years, crude cohort: P<0.001, PSM cohort: P<0.001) but not late recurrence( ≥ 2 years, crude cohort: P=0.692, PSM cohort: P=0.325). Multivariable Cox regression analysis suggested that PA-TACE was an independent protective factor prolonging early RFS, RFS and OS. Conclusions: PA-TACE is a safe intervention for huge HCC patients after liver resection and improves outcomes.

关键词： Postoperative transcatheter arterial chemoembolization Recurrence Prognosis

Assessment of alternated cooling and heating treatment by US combined CEUS in the VX2 rabbit liver tumor model

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Chinese Science Bulletin 2014年第9期59卷 865-873页

作者： cong Wei E.Shen Di Sun Aili Zhang Jianqi Sun Bing Hu Department of Ultrasound in Medicine Shanghai Jiao Tong University Affiliated Sixth People’s Hospital Shanghai Institute of Ultrasound in Medicine Department of Biomedical Engineering and Med-X Research Institute Shanghai Jiao Tong University

Inoperable liver tumors are often treated by thermal ablation that destroys the tumor in situ and spares the adjacent hepatic ***–physical treatment has many advantages,but treatment by freezing or heating alone has some *** taking the advantages and disadvantages of cryosurgery and thermotherapy into consideration,a new thermal technique that combines cryosurgery and radio frequency ablation has been proposed,thereby overcoming the disadvantages of each treatment strategy and improving therapeutic *** new approach remains to be systematically studied in the liver;therefore,this study was performed to estimate survival after alternated cooling and heating ablation therapy in a VX2 rabbit liver tumor *** days after VX2 carcinoma implantation into the rabbit liver,tumors were treated with alternated cooling and heating ablation *** were monitored for 6 months after treatment and assessed with ultrasound(US)and computed tomography at 1,7,14,and 30 days *** tumor-bearing animals served as the control *** results show that alternate freezing and heating ablation therapy resulted in a good recovery of VX2 *** with the control group,treated rabbits lived significantly longer(P\0.05),with 70%of treated animals surviving to 196 days posttreatment without metastasis or recurrence,while none of the controls did *** was no local recurrence in the treatment *** rabbits in the control group developed metastasis,while metastasis was only observed in 30% of treated *** results suggest that alternate cooling and heating ablation therapy can prolong the survival time of rabbits with VX2 liver tumors and is an effective method for tumor ***,we also showed in this model that contrast enhanced US is a valid follow-up approach to assess treatment effectiveness.

关键词：物理治疗肿瘤模型肝肿瘤后评估兔肝加热美国超声

Fabrication of nanoreactors based on polyoxoperoxometalates and enhancement of their catalytic activity

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Chinese Chemical Letters 2011年第7期22卷 875-878页

作者： Mei Jie Wei Chun Li Zhang cong Liang Sun Ang Li Xiao Hong Wang Key Lab of Polyoxometalate Science of Ministry of Education Faculty of Chemistry Northeast Normal University Changchun 130024 China

The nanoreactors were fabricated by reacting amphiphilic quaternary ammoniums and polyoxoperoxometalates Kn[PW12-xTix. O40-x（O2）x] （x = 1, 2 and 3; n =5, 7 and 9）（K5[PW11TiO39（O2）], KT[PWloTi2038（O2）2] and K9[PW9Ti3O37（O2）3]）. Fourier transform infrared spectroscopy （FT-IR）, transmission electron microscopy （TEM） were used to characterize the resulting samples. This kind of nanocatalysts could promote NH4SCN＇ degradation into simple inorganic compounds such as SO4^2-, HCO3^- and NO3^- only using oxygen as an oxidant under room conditions.

关键词： Catalytic wet air oxidation Thiocyanate Polyoxometalate Nanocatalysts

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场地挖土制备回填用泡沫水泥土性能研究

施工技术（中英文） 2024年第16期53卷 21-26页

作者：武亚夏芬揭双全陈兰生邵帅马聪深圳市建安(集团)股份有限公司广东深圳518040 深圳大学广东深圳518060

为了提高城市地下空间开挖土的利用率,试验研究了泡沫含量和土含量对开挖土泡沫混凝土回填性能的影响。结果表明:制备的泡沫混凝土不仅满足一般城市地下空间对回填性能的要求,也能满足一般天然地基对承载力的要求。增大泡沫含量能显著... 详细信息

为了提高城市地下空间开挖土的利用率,试验研究了泡沫含量和土含量对开挖土泡沫混凝土回填性能的影响。结果表明:制备的泡沫混凝土不仅满足一般城市地下空间对回填性能的要求,也能满足一般天然地基对承载力的要求。增大泡沫含量能显著提高开挖土泡沫混凝土的流动度,降低其湿密度,增大土含量则会导致工作性能的下降。开挖土泡沫混凝土的无侧限抗压强度随泡沫含量、土含量的升高而下降。导热系数随泡沫含量的升高而降低,随土含量升高而增大,主要是因为引入泡沫会使密度降低,而土含量升高则会降低密度。当泡沫含量≤0.4m^(3)时,开挖土耐水系数保持在0.9以上,泡沫含量超过0.4m^(3)时,耐水系数明显降低;增大土含量会轻微降低耐水性,当土含量超过40%时,耐水性仍能满足规范中的要求。因此,在实际工程应用中,为了尽可能提高开挖土的利用率,土含量应尽可能高于40%,但同时需控制泡沫含量不超过0.4m^(3)。

关键词：泡沫混凝土开挖土工作性能力学性能耐水性能

YME1L overexpression exerts pro-tumorigenic activity in glioma by promoting Gai1 expression and Akt activation

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Protein & Cell 2023年第3期14卷 223-229页

作者： Fang Liu Gang Chen Li-Na Zhou Yin Wang Zhi-qing Zhang Xihu Qin cong Cao Department of Neurosurgery The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical UniversityChangzhou 213004China Department of Neurosurgery TheFirst Affliated Hospital of SoochowUniversitySuzhou 215006China Department of Radiotherapy and Oncology Affliated Kunshan Hospital of Jiangsu UniversitySuzhou 215300China Department of Neurology and Clinical Research Center of Neurological Disease The Second Affiliated Hospital of Soochow UniversitySuzhou 215004China Jiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience Soochow UniversitySuzhou 215031China Department of General surgery The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical UniversityChangzhou 213004China

DearEditor,Identifying novel glioma-driven signaling molecules and exploring the corresponding molecularly targeted therapies are essential for better and effcient glioma ***1L(YME1 Like 1 ATPase),a primary member of the AAA family of ATPase,is located at the inner mitochondrial membrane(Anand et al.,2014;MacVicar et al.,2019;Ohba et al.,2020).YME1L is essential for maintaining mitochondrial morphology,function,and plasticity(Anand et al.,2014;MacVicar et al.,2019;Ohba et al.,2020).YME1L assembles into a homo-oligomeric complex within the inner mitochondrial membrane(Anand et al.,2014;MacVicar et al.,2019;Ohba et al.,2020).Moreover,YME1L can degrade mitochondrial proteins,including lipid-transferring proteins,IM translocation proteins.

关键词： glioma activation

蚂蚁筑巢对森林土壤氮库组分含量和分配的影响

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西部林业科学 2024年第3期53卷 144-153,160页

作者：闪昇阳陆梅李聪赵定蓉孙官发陈志明冯峻西南林业大学生态与环境学院云南昆明650224 西南林业大学水土保持学院云南昆明650224 中国林业科学研究院高原林业研究所云南昆明650233 纳帕海省级自然保护区管护局云南迪庆674400 云南省林木种苗工作站云南昆明650215

为阐明蚂蚁筑巢对纳帕海面山森林土壤氮循环的影响过程及机制,以该区云杉-冷杉森林群落为研究对象,比较蚁巢和非蚁巢2种野外实验处理土壤氮组分(全氮、碱解氮、硝态氮、铵态氮、微生物生物量氮)含量及其分配(碱解氮/全氮、硝态氮/全氮... 详细信息

为阐明蚂蚁筑巢对纳帕海面山森林土壤氮循环的影响过程及机制,以该区云杉-冷杉森林群落为研究对象,比较蚁巢和非蚁巢2种野外实验处理土壤氮组分(全氮、碱解氮、硝态氮、铵态氮、微生物生物量氮)含量及其分配(碱解氮/全氮、硝态氮/全氮、铵态氮/全氮、微生物生物量氮/全氮)的差异特征,分析蚂蚁筑巢活动引起土壤理化环境变化对氮库组分积累与分配的影响。结果显示:(1)蚂蚁筑巢显著影响土壤氮组分含量积累及分配(P<0.05)。其中,蚁巢土壤的全氮、硝态氮、铵态氮、碱解氮和微生物生物量氮含量是非蚁巢的2.2、3.5、1.4、4.2、1.8倍;蚁巢土壤的氮组分(碱解氮、硝态氮、铵态氮、微生物生物量氮)占全氮比例是非蚁巢的1.88、1.47、1.38、1.58倍;土壤氮库组分及其分配受不同处理、土层及交互作用的影响显著(P<0.05)。(2)回归分析显示,土壤铵态氮和硝态氮分别解释全氮变化的87.29%、80.84%。(3)曼特尔分析表明,氮库组分积累的主要驱动因子是土壤孔隙度、全磷和pH,土壤氮库组成分配的主要驱动因子是有机质、速效钾和速效磷。可得结论:蚂蚁筑巢显著改变土壤孔隙度、酸碱性、碳磷钾养分等环境因子,进而调控纳帕海面山森林土壤氮库组分含量的积累与分配。研究结果有助于理解高原湿地面山土壤氮积累过程的土壤动物学调控机制。

关键词：蚂蚁筑巢氮组分氮积累氮分配面山森林纳帕海

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复杂厚板钢结构焊接裂纹分析及对策

焊接 2024年第5期 75-80页

作者：朱瑞峰张俊宝吴崇志丛大志上海核工程研究设计院股份有限公司上海200233

在现代发电站结构设计中,通常采用钢结构和钢板-混凝土结构形成主体结构,通过协同作用实现建筑抗震,整个施工过程涉及大量的钢结构焊接工作。大厚板、复杂节点、空间受限等问题导致钢结构焊接出现了冷裂纹和层状撕裂问题,这些问题的起... 详细信息

在现代发电站结构设计中,通常采用钢结构和钢板-混凝土结构形成主体结构,通过协同作用实现建筑抗震,整个施工过程涉及大量的钢结构焊接工作。大厚板、复杂节点、空间受限等问题导致钢结构焊接出现了冷裂纹和层状撕裂问题,这些问题的起因既有预热、后热、焊接热输入控制等焊接工艺本身的问题,也有焊接接头布置及坡口设计不当的问题。该研究针对这些问题的起因进行了深入分析,采取了针对性措施改进加热方式、控制焊接热输入和优化焊接接头,解决了上述焊接裂纹问题。该研究积累的经验和提出的改进措施不仅对发电站的复杂厚板钢结构焊接有直接指导作用,对其他行业钢结构的焊接也有一定的借鉴作用。

关键词：钢结构焊接冷裂纹层状撕裂对策

Extended damage range of(Al0.3Cr0.2Fe0.2Ni0.3)3O4 high entropy oxide films induced by surface irradiation

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Chinese Physics B 2020年第6期29卷 374-378页

作者： Jian-cong Zhang Sen Sun Zhao-Ming Yang Nan Qiu Yuan Wang Key Laboratory of Radiation Physics and Technology Ministry of EducationInstitute of Nuclear Science and TechnologyCollege of PhysicsSichuan UniversityChengdu 610064China

Irradiation makes structural materials of nuclear reactors degraded and ***,the damage process of materials induced by irradiation is not fully elucidated,mostly because the charged particles only bombarded the surface of the materials(within a few microns).In this work,we investigated the effects of surface irradiation on the indirect irradiation region of the(Al0.3Cr0.2Fe0.2Ni0.3)3O4 high entropy oxide(HEO)films in detail by plasma surface *** results show that the damage induced by surface irradiation significantly extends to the indirect irradiation region of HEO film where the helium bubbles,dislocations,phase transformation,and the nickel oxide segregation were observed.

关键词： high entropy oxide films surface irradiation radiation-induced segregation vacancies extended irradiation damage region

Effects of different ingredients of zedoary on gene expression of HSC-T6 cells

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World Journal of Gastroenterology 2005年第43期11卷 6780-6786页

作者： Yuan Jiang Ze-Song Li Fu-Sheng Jiang Xin Deng cong-Shun Yao Guang Nie Shenzhen Shajing People's Hospital Shenzhen 518104 Guangdong Province China Shenzhen Yishengtang Biology Enterprise Company Shenzhen 518126 Guangdong Province China Shenzhen Donghu Hospital Shenzhen 518020 Guangdong Province China Teaching pharmacology and Research Section of Shenyang Pharmaceutial University Shenyang 110000 Liaoning Province China

AIM： To investigate the effects of four different ingredients of zedoary （Curcuma aromatica oil, Curcumol, β-elemence, and Curcumin） on the gene expressions of hepatic stellate cells （HSCs）, and to explore the molecular mechanism of zedoary against hepatic fibrosis at gene network level. METHODS： We detected the mRNA sequences of 50 liver fibrosis-related genes in GenBank and designed oligonucleotide probes. We synthesized oligonucleotides with PE8909 DNA synthesizing instrument, and carried out oligonucleotide microarray with OGR-04 dropping instrument and aldehyded glass chip. Cultured HSC-T6 cells were breated wibh different concentrations of Colchicine, Curcuma aromatica oil, Curcumol, β-elemence, and Curcumin. According to the experiment of cell toxicity, we took the appropriate concentrations of medicines that resulted in over 50% of cell survival as experiment concentrations. We collected the cells at 1, 6, 12, and 24 h, and extracted total RNA with TRIzol reagent, then labeled cDNAs with Cy3-dUTP and Cy5-dUTP. These labeled cDNAs were hybridized to an oligonucleotide microarray which was washed several times and scanned by scanner GenePix 4000B. Different gene expressions of HSC-T6 cells were analyzed by ImaGene 4.2 software. RESULTS： After HSC-T6 cells were cultured in a medium containing 6.25μg/mL Colchicine for 12 h, expression of TIMP-1 decreased 2.2-folds. After HSC-T6 cells were cultured in a medium containing 78.125 μg/mL of Curcuma aromatica oil for 24 h, the expression of TIMP-2 and IL-6 decreased 2.3- and 2.2-folds, respectively. Moreover, after HSC-T6 cells were cultured in a medium containing 1.5625 μg/mL of Curcumol for 12 h, the expression of TGFμ1 and P450a decreased 2.3- and 2.1-folds, respectively. CONCLUSION： Our results may show the possible molecular mechanism of Curcuma aromatica oil and Curcumol against hepatic fibrosis.

关键词： DNA microarray Curcuma aromatica oil Curcumol Hepatic stellate cells Hepatic fibrosis