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基于定子绕组改接的三相感应电动机轻载高效运行分析与试验

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电力自动化设备 2015年第9期35卷 168-173页

作者：从敏王秀和杨玉波山东大学电气工程学院山东济南250061

定子绕组改接可以在不改变供电电压的前提下,降低绕组相电压,提高轻载时感应电机的效率和功率因数。设计了1台380 V、3 k W、4极三相感应电动机样机,对不同绕组改接方式进行了仿真并将其与直接降压方式进行对比试验研究。结果表明:定子... 详细信息

定子绕组改接可以在不改变供电电压的前提下,降低绕组相电压,提高轻载时感应电机的效率和功率因数。设计了1台380 V、3 k W、4极三相感应电动机样机,对不同绕组改接方式进行了仿真并将其与直接降压方式进行对比试验研究。结果表明:定子绕组改接方式实现的高效节能效果与直接降压方式基本相同;根据负载合理选择定子绕组接法,可达到较高的效率和功率因数。

关键词：感应电动机定子轻载效率功率因数绕组绕组改接仿真

Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways

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Military Medical Research 2024年第4期11卷 500-520页

作者： Kun Zhang Meng-Xia Zhang Xiao-Xiang Meng Jing Zhu Jia-Jun Wang Yi-Fan He Ye-Hua Li Si-cong Zhao Zhe-min Shi Li-Na Zheng Tao Han Wei Hong Department of Histology and Embryology School of Basic Medical SciencesTianjin Medical UniversityTianjin 300070China Department of Hepatology and Gastroenterology Tianjin Union Medical CenterTianjin Medical UniversityTianjin Union Medical Center Affiliated to Nankai UniversityTianjin 300000China

Background:G-protein coupled receptors(GPCRs)are recognized as attractive targets for drug ***,it remains poorly understood how GPCRs,except for a few chemokine receptors,regulate the progression of liver ***,we aimed to reveal the role of GPR65,a proton-sensing receptor,in liver fibrosis and to elucidate the underlying ***:The expression level of GPR65 was evaluated in both human and mouse fibrotic ***,Gpr65-deficient mice were treated with either bile duct ligation(BDL)for 21 d or carbon tetrachloride(CCl4)for 8 weeks to investigate the role of GPR65 in liver fibrosis.A combination of experimental approaches,including Western blotting,quantitative real-time reverse transcription-polymerase chain reaction(qRT-PCR),and enzyme-linked immunosorbent assay(ELISA),confocal microscopy and rescue studies,were used to explore the underlying mechanisms of GPR65’s action in liver ***,the therapeutic potential of GPR65 inhibitor in the development of liver fibrosis was ***:We found that hepatic macrophage(HM)-enriched GPR65 was upregulated in both human and mouse fibrotic ***,knockout of Gpr65 significantly alleviated BDL-and CCl4-induced liver inflammation,injury and fibrosis in vivo,and mouse bone marrow transplantation(BMT)experiments further demonstrated that the protective effect of Gpr65knockout is primarily mediated by bone marrow-derived macrophages(BMMs).Additionally,in vitro data demonstrated that Gpr65 silencing and GPR65 antagonist inhibited,while GPR65 overexpression and application of GPR65 endogenous and exogenous agonists enhanced the expression and release of tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and transforming growth factor-β(TGF-β),all of which subsequently promoted the activation of hepatic stellate cells(HSCs)and the damage of hepatocytes(HCs).Mechanistically,GPR65 overexpression,the acidic pH and GPR65 exogenous agonist induced up-regulation of

关键词： GPR65 Hepatic fibrosis Hepatic macrophages Inflammation c-Jun N-terminal kinase Nuclear factorκB

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早产儿脑损伤动物模型的研究现状与展望

第三军医大学学报 2009年第22期31卷 2167-2170页

作者：赵聪敏鲁利群第三军医大学新桥医院儿科重庆400037 成都医学院第一附属医院儿科成都610500

近年来,产科技术和新生儿重症监护技术的不断提高使早产儿存活率明显增加,早产儿脑损伤发病率亦呈逐年增加趋势。存活者约35%遗留慢性神经障碍,如脑瘫、癫痫、学习困难和认知异常等[1]。缺氧缺血和感染是导致早产儿脑损伤的主要原因。... 详细信息

近年来,产科技术和新生儿重症监护技术的不断提高使早产儿存活率明显增加,早产儿脑损伤发病率亦呈逐年增加趋势。存活者约35%遗留慢性神经障碍,如脑瘫、癫痫、学习困难和认知异常等[1]。缺氧缺血和感染是导致早产儿脑损伤的主要原因。根据神经病理学，早产儿脑损伤可分为：

关键词：早产儿脑损伤动物模型

保险经营视角下政策性粮食作物保险的农户需求——基于黑龙江省“两大平原”地区740个种粮农户的问卷调查

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保险研究 2014年第12期 70-77页

作者：李丹刘从敏东北农业大学经济管理学院黑龙江哈尔滨150030

本文以黑龙江省"两大平原"地区6个地市740个农户为样本,从保险经营视角切入,选取相应的影响因素指标,运用二分类Logisitic回归模型对农户的粮食作物保险需求及其影响因素进行了系统分析。计量结果表明,商业保险投保经历、保单条款理解... 详细信息

本文以黑龙江省"两大平原"地区6个地市740个农户为样本,从保险经营视角切入,选取相应的影响因素指标,运用二分类Logisitic回归模型对农户的粮食作物保险需求及其影响因素进行了系统分析。计量结果表明,商业保险投保经历、保单条款理解能力、保额满意程度、保险公司防灾防损服务水平对农户政策性粮食作物保险需求呈正向影响,社会救济对农户政策性粮食作物保险需求呈负向影响,并依据相应影响方向提出政策建议。

关键词：粮食作物保险需求影响因素

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试论旅游纠纷仲裁解决机制

海南大学学报（人文社会科学版） 2010年第3期28卷 36-41页

作者：王崇敏齐虎海南大学法学院海南海口570228

旅游活动中,法律关系错综复杂,诸多因素易引发旅游纠纷。针对旅游纠纷具有复杂性、标的小、急迫性等特征,仲裁制度在解决旅游纠纷方面相较诉讼等其他解纷手段具有较大的优势。充分重视仲裁制度在旅游纠纷解决机制中的作用,对于优化旅游... 详细信息

旅游活动中,法律关系错综复杂,诸多因素易引发旅游纠纷。针对旅游纠纷具有复杂性、标的小、急迫性等特征,仲裁制度在解决旅游纠纷方面相较诉讼等其他解纷手段具有较大的优势。充分重视仲裁制度在旅游纠纷解决机制中的作用,对于优化旅游软环境有着重要意义。要通过建立旅游仲裁中心,组建旅游仲裁专家队伍,推行巡回旅游仲裁庭制度,试行临时仲裁制度,尝试网上仲裁等多方面的努力,建立起高效便捷的旅游纠纷仲裁解决机制。

关键词：旅游纠纷仲裁旅游仲裁机制构建

The role of innate immunity in diabetic nephropathy and their therapeutic consequences

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Journal of Pharmaceutical Analysis 2024年第1期14卷 39-51页

作者： min Yang Chun Zhang Department of Nephrology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China

Diabetic nephropathy (DN) is an enduring condition that leads to inflammation and affects a substantial number of individuals with diabetes worldwide. A gradual reduction in glomerular filtration and emergence of proteins in the urine are typical aspects of DN, ultimately resulting in renal failure. Mounting evidence suggests that immunological and inflammatory factors are crucial for the development of DN. Therefore, the activation of innate immunity by resident renal and immune cells is critical for initiating and perpetuating inflammation. Toll-like receptors (TLRs) are an important group of receptors that identify patterns and activate immune responses and inflammation. Meanwhile, inflammatory responses in the liver, pancreatic islets, and kidneys involve inflammasomes and chemokines that generate pro-inflammatory cytokines. Moreover, the activation of the complement cascade can be triggered by glycated proteins. This review highlights recent findings elucidating how the innate immune system contributes to tissue fibrosis and organ dysfunction, ultimately leading to renal failure. This review also discusses innovative approaches that can be utilized to modulate the innate immune responses in DN for therapeutic purposes.

关键词： Innate immunity Diabetic nephropathy Inflammation Toll-like receptor Inflammasomes

Is the Cape Stone Forest in Shantou City formed by wave erosion? A comparison of the pedestal rocks on the coasts and the mountains of Queshi in eastern Guangdong, China

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Journal of Mountain Science 2024年第5期21卷 1447-1463页

作者： CHEN min WANG Wei School of Geography South China Normal UniversityGuangzhou 510631China

Cape Stone Forest is a group of granite rock pillars(pedestal rocks) towering over Shilin Lake, on the southern shore of Shantou Bay in eastern Guangdong, China. The rock pillars were previously identified as sea stacks because they have marine notch-like concave sidewalls at their base, and more importantly, the lake is immediately adjacent to the bay, which is exposed to the open sea. However, rock pillars similar in shape and size can also be found at the top of Queshi Mountain, which is only about 300 meters northwest of the lake and about 85 meters above sea level. Therefore, the marine origin of Cape Stone Forest is seriously questioned. In this study, 3D imagery and drone technology were used to collect data in the investigations without direct manual measurements in the water or on the mountain. It shows that the concave sidewalls of the rock pillars in the lake and on the mountains occur at different heights and are exposed to different directions, while a natural sea stack on Mayu Island at the mouth of Shantou Bay has a horizontal notch parallel to the sea level, although the granite rock of the sea stack is the same as that of the lake and the mountains. The eastern side of the island, where the sea stack is located, is exposed to the open sea but blocks large waves for the rock pillars in the lake. Therefore, the origin of Cape Stone Forest cannot be explained by wave-based mechanisms. The only satisfactory explanation that takes into account all the field evidence is that the narrow rock pillars of the lake and mountain were formed by chemical weathering that penetrated closely the spaced joints of the granite rock, and the notch-like concave sidewalls were formed by more effective chemical weathering at the base of the pillars.

关键词： Pedestal rock Granite Closely spaced joints Wave erosion Chemical weathering

Insights into carbon dioxide sequestration into coal seams through coupled gas flow-adsorption-deformation modelling

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第1期16卷 26-40页

作者： Hywel Thomas min Chen Geoenvironmental Research Centre Cardiff School of EngineeringCardiff UniversityQueen’s BuildingsThe ParadeNewport RoadCardiffCF243AAUK Key Laboratory of Marine Geology Tongji UniversityShanghai200092China

Injecting carbon dioxide(CO_(2))into coal seams may unlock substantial carbon sequestration *** the coal acts like a carbon filter,it can preferentially absorb significant amounts of CO_(2).To explore this further,desorption of the adsorbed gas due to pressure drop is investigated in this paper,to achieve an improved understanding of the long-term fate of injected CO_(2) during post-injection *** paper presents a dual porosity model coupling gas flow,adsorption and geomechanics for studying coupled processes and effectiveness of CO_(2) sequestration in coals.A new adsorption?desorption model derived based on thermodynamics is incorporated,particularly,the desorption hysteresis is *** reliability of the proposed adsorption-desorption isotherm is examined via validation *** is indicated that occurrence of desorption hysteresis is attributed to the adsorption-induced pore *** injection ceases,the injected gas continues to propagate further from the injection well,while the pressure in the vicinity of the injection well experiences a significant *** the adsorbed gas near the well also decreases,this decrease is less compared to that in pressure because of desorption *** unceasing spread of CO_(2) and drops of pressure and adsorbed gas depend on the degree of desorption hysteresis and heterogeneity of coals,which should be considered when designing CO_(2) sequestration into coal seams.

关键词： CO_(2)geological storage Coal seam Adsorption Desorption hysteresis

Universal method for designing periodic orbits by homotopy classes in the elliptic restricted three-body problem

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Astrodynamics 2024年第1期8卷 175-188页

作者： Yue Zheng min Zhao School of Electronic Engineering Xi’an Aeronautical InstituteXi’an710077China School of Aircraft Engineering Xi’an Aeronautical InstituteXi’an710077China School of Astronautics Northwestern Polytechnical UniversityXi’an710072China

The current methods for designing periodic orbits in the elliptic restricted three-body problem(ERTBP)have the disadvantages of targeting limited orbits and ergodic searches and considering only symmetric orbits.A universal method for designing periodic orbits is proposed in this ***,the homotopy classes of orbits are structured based on their topological ***,a dynamic model based on homotopy classes,ranging from the circular restricted three-body problem(CRTBP)to the ERTBP,can be built using the homotopy ***,a multi-and a single-period orbit were selected based on the resonance ***,the corresponding orbit in the ERTBP was computed by modifying the initial condition of the orbit in the *** method,without an ergodic search,can extend to any orbit,including an asymmetric orbit in the CRTBP,to the ERTBP model,and the two orbits are of the same homotopy *** of the Earth–Moon ERTBP are presented to verify the efficiency of this method.

关键词： periodic orbit elliptic restricted three-body problem(ERTBP) topology homotopy circular restricted three-body problem(CRTBP)