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一维气候模式的灵敏度分析

大气科学 1990年第1期14卷 72-82页

作者：李肇新 hervéLeTreut 法国动力气象实验室

在本文中我们设计了一个只有垂直方向的一维气候模式。该模式可以用来研究大气中CO_2气体浓度从330增加到660ppm时地面温度的变化。同时我们将分析几个反馈机制对气候系统灵敏度的贡献,其中包括大气湿度反馈、云反馈和地面反射率反馈等... 详细信息

在本文中我们设计了一个只有垂直方向的一维气候模式。该模式可以用来研究大气中CO_2气体浓度从330增加到660ppm时地面温度的变化。同时我们将分析几个反馈机制对气候系统灵敏度的贡献,其中包括大气湿度反馈、云反馈和地面反射率反馈等机制。

关键词：一维气候模式灵敏度大气 CO2

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微通道内气-液传质研究

化工学报 2006年第6期57卷 1296-1303页

作者：乐军陈光文袁权罗灵爱 LE GALL hervé 中国科学院大连化学物理研究所 LOCIE 3/ ESIGEC 3/ Université de Savoie Campus ScientifiqueSavoie Technolac73376Le Bourget-du-Lac cedexFrance DCPR-CNRS-ENSIC 1rue Grandville BP 45154001 NANCY CedexFrance

以CO2-H2O为模型体系,实验考察了当量直径为667 μm的单通道和16个并行通道内的气-液传质行为.实验发现,液体表观速度增加,单通道内液侧体积传质系数明显提高;同一液体表观速度下,液侧体积传质系数随气体表观速度增加而增加;在实验数据... 详细信息

以CO2-H2O为模型体系,实验考察了当量直径为667 μm的单通道和16个并行通道内的气-液传质行为.实验发现,液体表观速度增加,单通道内液侧体积传质系数明显提高;同一液体表观速度下,液侧体积传质系数随气体表观速度增加而增加;在实验数据基础上关联了液侧体积传质系数与气-液两相流参数间的关系.微通道内的液侧体积传质系数较常规尺度气-液接触设备至少高1～2个数量级.并讨论了并行微通道内气-液两相流分配特性对整体传质性能的影响,表明合理设计气、液流动分布结构,可保证微通道内优异的传质特性.

关键词：微通道气-液两相流传质过程强化

Almitrine for COVID-19 critically ill patients – a vascular therapy for a pulmonary vascular disease: Three case reports

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World Journal of Clinical Cases 2021年第14期9卷 3385-3393页

作者： Pierre Huette Osama Abou Arab Vincent Jounieaux Mathieu Guilbart Mohamed Belhout Guillaume Haye hervéDupont Christophe Beyls Yazine Mahjoub Department of Anaesthesia and Critical Care Amiens Hospital UniversityAmiens 80000France Department of Respiratory Medicine Amiens Hospital UniversityAmiens 80000France Department of Pharmacy Amiens Hospital UniversityAmiens 80000France

BACKGROUND Several reports with clinical,histological and imaging data have observed the involvement of lung vascular function to explain the severe hypoxemia in coronavirus disease 2019(COVID-19)*** has been hypothesized that an increased pulmonary blood flow associated with an impairment of hypoxic pulmonary vasoconstriction is responsible for an intrapulmonary ***-19 may lead to refractory hypoxemia(PaO_(2)/FiO_(2) ratio below 100 mmHg)despite mechanical ventilation and prone *** hypothesized that the use of a pulmonary vasoconstrictor may help decrease the shunt and thus enhance *** SUMMARY We report our experience with three patients with refractory hypoxemia treated with almitrine to enhance *** dose almitrine(Vectarion®;Servier,Suresnes,France)was started at an infusion rate of 4μg×kg/min on a central *** PaO_(2)/FiO_(2) ratio and total respiratory system compliance during almitrine infusion were *** the three patients,the PaO_(2)/FiO_(2) ratio time-course showed a dramatic increase whereas total respiratory system compliance was *** three patients were discharged from the intensive care *** intensive care unit length of stay for patient 1,patient 2 and patient 3 was 30 d,32 d and 31 d,*** from mechanical ventilation was performed 13 d,18 d and 15 d after almitrine infusion for patient 1,2 and 3,*** found no deleterious effects on the right ventricular function,which was similar to previous studies on almitrine *** Almitrine may be effective and safe to enhance oxygenation in coronavirus disease 2019 *** controlled studies are required.

关键词： COVID-19 Treatment Acute vascular distress syndrome Almitrine Intensive care unit Safety Case report

Trial of Spesolimab for Generalized Pustular Psoriasis

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四川生理科学杂志 2021年第10期43卷 1727-1727页

作者： hervé Bachelez From Service de Dermatologie Assistance Publique–Hôpitaux de Paris Hôpital Saint-Louis and INSERM Unité 1163 Imagine Institute of Genetic Diseases Université de Paris — both in Paris (H.B.) the Department of Dermatology Hospital Sultanah Aminah Johor Bahru Clinical School Johor Bahru Monash University Malaysia Subang Jaya Malaysia (S.-E.C.) the Dermatology Department Hedi Chaker University Hospital Sfax Tunisia (S.M. H.T.) the Institute of Infection Immunity and Inflammation University of Glasgow Glasgow United Kingdom (A.D.B.) the Department of Dermatology National Taiwan University Hospital and National Taiwan University College of Medicine Taipei Taiwan (T.-F.T.) the Department of Geriatric and Environmental Dermatology Nagoya City University Graduate School of Medical Sciences Nagoya Japan (A.M.) the Department of Dermatology University Hospital Basel Basel Switzerland (A.A.N.) the Department of Dermatology Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou (M.Z.) and the Department of Dermatology Huashan Hospital Fudan University (J.X.) and Boehringer Ingelheim (China) Investment Company (H.H.) Shanghai — all in China Washington University School of Medicine Division of Dermatology St. Louis (M.J.A.) Boehringer Ingelheim Pharmaceuticals Ridgefield CT (S.R. D.H.) Boehringer Ingelheim International Ingelheim (S.D.V. K.T.) the Medical Clinic Department of Sports Medicine University of Tuebingen Tuebingen (K.T.) and Boehringer Ingelheim International Biberach (C.T.) — all in Germany and the Icahn School of Medicine at Mount Sinai New York (M.G.L.).

Methods:In a phase 2 trial,we randomly assigned patients with a GPP flare in a 2:1 ratio to receive a single 900-mg intravenous dose of spesolimab or *** in both groups could receive an open-label dose of spesolimab on day 8,an open-label dose of spesolimab as a rescue medication after day 8,or both and were followed to week *** primary end point was a Generalized Pustular Psoriasis Physician Global Assessment(GPPGA)pustulation subscore of 0(range,0[no visible pustules]to 4[severe pustulation])at the end of week *** key secondary end point was a GPPGA total score of 0 or 1(clear or almost clear skin)at the end of week 1;scores range from 0 to 4,with higher scores indicating greater disease severity.

关键词： Psoriasis intravenous medication

Factors associated with mothers’health care-seeking behaviours for childhood fever in Burkina Faso:findings from repeated cross-sectional household surveys

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Global Health Research and Policy 2022年第1期7卷 139-150页

作者： Hermann Badolo Aristide R.Bado hervéHien Nicolas Méda A.Sathiya Susuman Department of Statistics and Population Studies Faculty of Natural SciencesUniversity of the Western CapeCape TownSouth Africa National Institute of Public Health(INSP) OuagadougouBurkina Faso Health Sciences Research Institute(IRSS) OuagadougouBurkina Faso Health Sciences Research Institute(IRSS) Bobo-DioulassoBurkina Faso West African Health Organization(WAHO) Bobo-DioulassoBurkina Faso Health Sciences Training and Research Unit UniversitéOuaga I Pr.Joseph Ky-ZerboOuagadougouBurkina Faso

Introduction:Fever is one of the most frequent reasons for paediatric consultations in Burkina Faso,but health care-seeking behaviours and the factors associated with health care-seeking in the event of childhood fever are poorly *** study aims to analyse the health care-seeking behaviours and the factors associated with health care-seeking for childhood fever in Burkina ***:This study used the data from the baseline and endline surveys conducted to evaluate the impact of the Performance-Based Financing program in Burkina *** and multivariate binary logistic regression analyses were used to identify the factors associated with appropriate healthcare-seeking for childhood *** ratios were estimated to assess the strength of associations and 95%confidence intervals(CIs)were used for significance *** were cleaned,coded and analysed using Stata software version ***:Among the children under five who had a fever,75.19%and 79.76%sought appropriate health care in 2013 and 2017,*** 24-59 months old(AOR:0.344,95%CI 0.182-0.649 in 2013 and AOR:0.208,95%CI 0.115-0.376 in 2017),living in a very wealthy household(AOR:2.014,95%CI 1.149-3.531 in 2013 and AOR:2.165,95%CI 1.223-3.834 in 2017),having a mother with a secondary or higher level of education or having made at least four antenatal care visits were significantly associated with seeking appropriate health care for childhood *** in an area where the health facility is safe was also significantly associated with seeking appropriate care for childhood ***:The findings underscore the need to concentrate efforts aiming at sensitizing the population(especially women of childbearing age)to improve sanitation and the use of family planning(household composition),skilled antenatal care and postnatal care to help reduce the prevalence of fever in children under five and improve the use of medical healthcare for childhood fever.

关键词： Childhood fever Illness Prevalence Health care Health care-seeking Burkina Faso

Plasticity of wheat seedling responses to K^(+) deficiency highlighted by integrated phenotyping of roots and root hairs over the whole root system

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Stress Biology 2023年第1期3卷 69-83页

作者： Ikram Madani Jean-Benoit Peltier Martin Boeglin hervé Sentenac Anne-Aliénor Véry Institut des Sciences des Plantes de Montpellier UMR 5004 CNRS-386 INRAE-Université Montpellier-Institut AgroCampus SupAgro-INRAE Bat 7Place VialaMontpellier 34060 Cedex 2France

The availability in the soil of potassium(K^(+)),a poorly mobile macronutrient required in large quantities for plant growth,is generally suboptimal for crop production in the absence of fertilization,making improvement of the ability of crops to adapt to K^(+)deficiency stress a major *** the uptake capacity of the root system is among the main strategies to achieve this ***,we report an integrative approach to examine the effect of K^(+)deficiency on the development of young plant entire root system,including root hairs which are known to provide a significant contribution to the uptake of poorly mobile nutrients such as K^(+),in two genetically distant wheat varieties.A rhizobox-type methodology was developed to obtain highly-resolved images of root and root hairs,allowing to describe global root and root hair traits over the whole root system via image analysis *** two wheat varieties responded differently to the K^(+)shortage:Escandia,a wheat ancestor,reduced shoot biomass in condition of K^(+)shortage and substantially increased the surface area of its root system,specifically by increasing the total root hair *** Zenati,a landrace,conversely appeared unresponsive to the K^(+)shortage but was shown to constitutively express,independently of the external K^(+)availability,favorable traits to cope with reduced K^(+)availability,among which a high total root hair ***,valuable information on root system adaptation to K^(+)deficiency was provided by global analyses including root hairs,which should also be relevant for other nutrient stresses.

关键词： K^(+)deficiency Root hair Root system Phenotyping Wheat Rhizobox Root plasticity

Problematic of Accounting Evolutivity: An Answer Through the Analysis of SYSCOHADA in the Cameroonian Context

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Journal of Modern Accounting and Auditing 2018年第12期14卷 648-670页

作者： Kadouamal Souleymanou hervé Ndoume Essingone The University of Maroua Maroua Cameroon National Institute of Management Sciences Libreville Gabon

This article describes the conceptual, practical, and organizational difficulties of evolutivity of a new uniform act. Besides the problem of stock market listing of most African countries enterprises seen among many other things as a prerequisite to the internationalization of accountancy, particularly, to the emergency of the full or total or not at all implementation of an innovation, it is a matter of bringing the foundations into focus. The most expected heated debates on the SYSCOHADA accounting evolutivity in view of the implementation of its new uniform act, of the quality of information provided and the informational pertinence are therefore collected through semi-direct interviews from accountants and auditors. A situational analysis is carried out in the Cameroonian context. From a qualitative approach, the potential constraints are explained. The interest of the analysis of this evolutivity is that, despite its temporal status, it is intimately linked to organizational and social realities.

关键词： uniform act SYSCOHADA scalability constraints Cameroon

Ordinary Biodiversity, Local Stakeholders and Forest Management as a Driver for Regional Sustainable Development

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Open Journal of Forestry 2014年第3期4卷 249-258页

作者： hervé Brédif Laurent Simon Université Paris 1 Panthéon-Sorbonne UMR LADYSS CNRS Institut de Géographie Paris France

The protection of biodiversity which had long been bounded up with emblematic “natural” spaces is now increasingly focusing on ordinary biodiversity and rural agricultural land and forests as well as on urban and peri-urban spaces. Such ordinary biodiversity has its own specific features which make it both a relative and uncertain topic of research. Traditional nature protection instruments do not work on this dimension of the planet’s living tissue and new tools need to be deployed in conjunction with regional and local stakeholders that will provide long-term sustainable solutions for biodiversity and for local and regional development more generally. Research conducted on the Plateau de Millevaches explores the possibilities for shared caring for this biodiversity.

关键词： Biodiversity Conservation Forest Stakeholder Participation Decision Making

Potential role of lava lizards as pollinators across the Galápagos Islands

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Integrative Zoology 2020年第2期15卷 144-148页

作者： Sandra hervÍAS-PAREJO Manuel NOGALES Beatriz GUZMÁN María del Mar TRIGO Jens MOLESEN Pablo VARGAS Ruben HELENO Anna TRAVESET Global Change Research Group Mediterranean Institute for Advanced StudiesMallorcaBalearic IslandsSpain Island Ecology and Evolution Research Group Institute of Natural Products and AgrobiologyCanary IslandsSpain Royal Botanical Garden of Madrid MadridSpain Department of Plant Biology Málaga UniversityMálagaSpain Department of Bioscience Aarhus UniversityAarhusDenmark Centre for Functional Ecology Department of Life SciencesUniversity of CoimbraCoimbraPortugal

Lizards have been reported as important pollinators on several oceanic *** we evaluate the potential role of Galápagos lava lizards(Microlophus spp.)as pollinators across their *** 3 years,we sampled pollen transport by 9 lava lizard species on the 10 islands where they are present,including 7 single-island ***,only 25 of 296 individuals sampled(8.4%)transported pollen of 10 plant species,the most common being Prosopis juliflora,Exodeconus miersii,Sesuvium *** Cordia *** least 8 of these plant species were native,and none were confirmed as introduced to the *** the low overall proportion of individuals carrying pollen,this was observed in 7 of the nine lizard species,and on 8 of the ten main islands(Española,Fernandina,Floreana,Isabela,Marchena,Pinta,Santa Cruz and Santiago),suggesting that this is a widespread *** results reported here support the potential role of lava lizards as pollinators across their radiation,although they may represent a relatively modest contribution when compared with birds and ***,we cannot discard that lizards may be ecologically significant for particular plant species and ecosystems given the specific climatic condition and functional diversity of each island.

关键词： flower visitation Microlophus spp. mutualistic interactions pollination vertebrate radiation