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Hemoglobin loss method calculates blood loss during pancreaticoduodenectomy and predicts bleeding-related risk factors

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World Journal of Gastrointestinal Surgery 2024年第2期16卷 419-428页

作者： Chao Yu yi-Min Lin Guo-Zhe Xian Department of Hepatobiliary Surgery Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina

BACKGROUND The common clinical method to evaluate blood loss during pancreaticoduoden-ectomy(PD)is visual inspection,but most scholars believe that this method is extremely subjective and ***,there is no accurate,objective me-thod to evaluate the amount of blood loss in PD *** retrospectively analyzed the clinical data of 341 patients who underwent PD in Shandong Provincial Hospital from March 2017 to February *** to different surgical methods,they were divided into an open PD(OPD)group and a laparoscopic PD(LPD)*** differences and correlations between the in-traoperative estimation of blood loss(IEBL)obtained by visual inspection and the intraoperative calculation of blood loss(ICBL)obtained using the Hb loss method were ***,IEBL and perioperative calculation of blood loss(PCBL)were compared between the two groups,and single-factor regression analysis was *** There was no statistically significant difference in the preoperative general patient information between the two groups(P>0.05).PD had an ICBL of 743.2(393.0,1173.1)mL and an IEBL of 100.0(50.0,300.0)mL(Pci):53.82-549.62;P=0.017]was an independent risk factor for *** addition,the single-factor analysis of PCBL showed that body mass index(BMI)(95%ci:0.62-76.75;P=0.046)and preoperative total bilirubin>200μmol/L(95%ci:7.09-644.26;P=0.045)were independent risk factors for *** ICBLs of the LPD group and OPD group were 767.7(435.4,1249.0)mL and 663.8(347.7,1138.2)mL,respectively(P>0.05).The IEBL of the LPD group 200.0(50.0,200.0)mL was slightly greater than that of the OPD group 100.0(50.0,300.0)mL(P>0.05).PCBL was greater in the LPD group than the OPD group[1061.6(612.3,1632.3)mL vs 806.1(375.9,1347.6)mL](P<0.05).CONCLUSION The ICBL in patients who underwent PD was greater than

关键词： Pancreaticoduodenectomy Hemoglobin loss Calculated blood loss Estimated blood loss

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Effects of loneliness and isolation on cardiovascular diseases:a two sample Mendelian Randomization Study

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Journal of Geriatric Cardiology 2024年第3期21卷 340-348页

作者： Jia-yin CAI Xin WANG Cong-yi ZHENG Xue CAO Zhen HU Run-Qing GU yi-Xin TIAN Ye TIAN Lan SHAO Lin-Feng ZHANG Zeng-Wu WANG Division of Prevention and Community Health National Center for Cardiovascular DiseaseNational Clinical Research Center of Cardiovascular DiseaseState Key Laboratory of Cardiovascular DiseaseFuwai HospitalPeking Union Medical College&Chinese Academy of Medical SciencesBeijingChina

BACKGROUND Loneliness and isolation are associated with multiple cardiovascular diseases(CVDs),but there is a lack of research on whether they were causally *** conducted a Mendelian Randomization(MR)study to explore causal relationships between loneliness and isolation and multiple *** Single nucleotide polymorphisms associated with loneliness and isolation were identified from a genome-wide association study(GWAS)of 455,364 individuals of European ancestry in the IEU GWAS *** data for 15 CVDs were also obtained from the IEU GWAS *** used three MR methods including inverse variance weighting,MR-Egger,and weighted median estimation to assess the causal effect of exposure on ***'s Q test and MR-Egger intercept test were used to evaluate the heterogeneity and *** MR analysis showed that loneliness and isolation were significantly associated with essential hypertension(OR=1.07,95%ci:1.03-1.12),atherosclerotic heart disease(OR=1.04;95%ci:1.02-1.06),myocardial infarction(OR=1.02;95%ci:1-1.04)and angina(OR=1.04;95%ci=1.02-1.06).No heterogeneity and pleiotropy effects were found in this *** Causal relationship of loneliness and isolation with CVDs were found in this study.

关键词： diseases cardiovascular angina

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生成治理共同体:公共文化服务的优化路径

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图书馆论坛 2024年第4期44卷 84-92页

作者：慈勤英袁瑜武汉大学社会学院乐山师范学院

深化多元治理促进公共文化场所的保护与发展是公共文化服务高质量发展的重要方向。文章以质性研究方法对四川省文庙、龙神祠公共文化服务展开调查,发现存在因政府单一依赖、分散治理带来的公共文化服务供给不足等状况,提出通过高校领办... 详细信息

深化多元治理促进公共文化场所的保护与发展是公共文化服务高质量发展的重要方向。文章以质性研究方法对四川省文庙、龙神祠公共文化服务展开调查,发现存在因政府单一依赖、分散治理带来的公共文化服务供给不足等状况,提出通过高校领办、政府负责、社会组织参与形成制度化的治理共同体是有效解决途径。为提升公共文化服务质量,三方通过目标整合激发治理动能、责任分配整合治理资源、制度约定规范治理行为,形成目标、行动、利益共同体,激活多元力量的参与效能感,激发场所发展内生动力。这种多元治理模式表明,以协商、信任凝聚多元参与利益,以善治、多元互嵌重塑治理结构,以赋权、赋能和制度保障拓展社会组织参与渠道是优化公共文化服务多元治理的路径。

关键词：治理共同体公共文化服务多元参与社会组织

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新型口服硫酸盐溶液用于结肠息肉术前清肠的临床研究

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中国临床药理学杂志 2024年第8期40卷 1136-1139页

作者：刘静叶献词徐正富汪全红铜陵市人民医院消化内科安徽铜陵244000 铜陵市人民医院内镜中心安徽铜陵244000

目的本研究旨在探究复方口服硫酸盐溶液用于结肠息肉术前清肠的临床疗效。方法将接受结肠息肉切除术的患者按照队列法分为对照组和试验组。对照组患者给予复方聚乙二醇电解质散,在结肠镜检查前4~6 h开始服用,2 h内服完4 L溶液;试验组... 详细信息

目的本研究旨在探究复方口服硫酸盐溶液用于结肠息肉术前清肠的临床疗效。方法将接受结肠息肉切除术的患者按照队列法分为对照组和试验组。对照组患者给予复方聚乙二醇电解质散,在结肠镜检查前4~6 h开始服用,2 h内服完4 L溶液;试验组患者给予复方口服硫酸盐溶液,术前1天的傍晚服用复方口服硫酸盐溶液1.5 L,手术当天重复前1天傍晚的服药方法。比较2组患者的肠道清洁程度(波士顿肠道准备评分,BBPS),肠道准备依从性,药物耐受性,患者满意度以及药物不良反应发生率。结果对照组和试验组各40例,对照组和试验组BBPS总评分分别为(6.68±1.19)和(7.43±1.23)分,在统计学上差异有统计学意义(P0.05)。结论服用复方口服硫酸盐溶液进行肠道准备,其肠道清洁效果优于复方聚乙二醇电解质散,患者的依从性以及对药物的耐受性更高,并且可以有效提高患者的满意度。

关键词：复方聚乙二醇电解质散复方口服硫酸盐溶液结肠息肉肠道准备临床疗效

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Association of Mosaic Chromosomal Alterations and Genetic Factors with the Risk of cirrhosis

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Journal of Clinical and Translational Hepatology 2024年第6期12卷 562-570页

作者： Xinyuan Ge Lu Zhang Maojie Liu Xiao Wang Xin Xu Yuqian Yan Chan Tian Juan Yang Yang Ding Chengxiao Yu Jing Lu Longfeng Jiang Qiang Wang Qun Zhang ci Song Department of Epidemiology China International Cooperation Center on Environment and Human HealthCenter for Global HealthSchool of Public HealthNanjing Medical UniversityNanjingJiangsuChina The Dumont-UCLA Transplant Center Division of Liver and Pancreas TransplantationDepartment of SurgeryDavid Geffen School of Medicine at UCLALos AngelesCAUSA Department of Health Promotion Center Jiangsu Province Hospital and Nanjing Medical University First Affiliated HospitalNanjingJiangsuChina Department of Infectious Disease The First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsuChina Department of Clinical Science Intervention and Technology(CLINTEC)Karolinska InstitutetStockholmSweden Changzhou Medical Center Nanjing Medical UniversityNanjingJiangsuChina Research Units of Cohort Study on Cardiovascular Diseases and Cancers Chinese Academy of Medical SciencesBeijingChina Collaborative Innovation Center for Cancer Personalized Medicine Nanjing Medical UniversityNanjingJiangsuChina

Background and Aims:Age-related mosaic chromosomal alterations(mCAs)detected from genotyping of blood-de-rived DNA are structural somatic variants that indicate clonal *** study aimed to investigate whether mCAs contribute to the risk of cirrhosis and modify the effect of a polygenic risk score(PRS)on cirrhosis risk ***:mCA call sets of individuals with European ancestry were obtained from the UK *** PRS was constructed based on 12 susceptible single-nucleotide poly-morphisms for *** proportional hazard models were applied to evaluate the associations between mCAs and cirrhosis ***:Among 448,645 individuals with a median follow-up of 12.5 years,we identified 2,681 cas-es of cirrhosis,1,775 cases of compensated cirrhosis,and 1,706 cases of decompensated *** to non-carriers,individuals with copy-neutral loss of heterozygosity mCAs had a significantly increased risk of cirrhosis(hazard ratio(HR)1.42,95%confidence interval(ci)1.12-1.81).This risk was higher in patients with expanded cell fractions of mCAs(cell fractions≥10%*** fractionscially for the risk of decompensated cirrhosis(HR 2.03[95%ci 1.09-3.78]vs.1.14[0.80-1.64]).In comparison to non-carriers of mCAs with low genetic risk,individuals with expanded copy-neutral loss of heterozygosity and high genetic risk showed the highest cirrhosis risk(HR5.39[95%ci 2.41-12.07]).Conclusions:The presence of mCAs is associated with increased susceptibility to cirrhosis risk and could be combined with PRS for personalized cirrhosis risk stratification.

关键词： UK Biobank cirrhosis Mosaic chromosomal alterations Polygenic risk score Genetic susceptibility Interaction effect

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基于双重距离的多目标粒子群优化算法

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控制与决策 2024年第6期39卷 1801-1809页

作者：慈雨荣淼彭晨上海大学机电工程与自动化学院上海200444

多目标粒子群优化(multi-objective particle swarm optimization,MOPSO)算法在维护收敛性的同时搜索分布良好的最优解集较为费力.为此,提出一种基于双重距离的MOPSO,由种群的平均距离定义粒子的邻域空间,邻域粒子数为粒子的等级,数量越... 详细信息

多目标粒子群优化(multi-objective particle swarm optimization,MOPSO)算法在维护收敛性的同时搜索分布良好的最优解集较为费力.为此,提出一种基于双重距离的MOPSO,由种群的平均距离定义粒子的邻域空间,邻域粒子数为粒子的等级,数量越多,粒子的等级越大.当等级相同时,算法结合粒子的拥挤距离选择最优粒子,并更新外部归档集.此外,算法结合粒子的变异行为避免陷入局部最优.在对比实验中,该算法在收敛性和多样性上可取得较优结果.最后,将该算法应用到电力系统的环境/经济调度模型(environmental/economic dispatch,EED),也可获得性能较好的解集.

关键词：平均距离拥挤距离邻域信息多目标粒子群优化多目标问题环境/经济调度

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Associations Between Active,Passive Smoking and the Risk of Nonalcoholic Fatty Liver Disease

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Journal of Clinical and Translational Hepatology 2024年第1期12卷 113-118页

作者： Xinyuan Ge Jing Lu Chengxiao Yu Wen Guo Ting Tian Xin Xu Yuqing Ding Jiaxin Gao Wei Zhao Xiaohua Zhou Qingqing Diao Hongxia Ma Qun Zhang ci Song Hongbing Shen Department of Epidemiology China International Cooperation Center on Environment and Human HealthCenter for Global HealthSchool of Public HealthNanjing Medical UniversityNanjingJiangsuChina Health Promotion Center Jiangsu Province Hospital and the First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsuChina Research Units of Cohort Study on Cardiovascular Diseases and Cancers Chinese Academy of Medical SciencesBeijingChina Collaborative Innovation Center for Cancer Personalized Medicine Nanjing Medical UniversityNanjingJiangsuChina

Nonalcoholic fatty liver disease(NAFLD)is the most common chronic liver disease with an estimated worldwide prevalence of 32.4%.1 The multisystem condition is related to an increased risk of liver-related and cardiovascular extrahepatic diseases.2 Smoking is the leading preventable risk factor for premature disability and *** NAFLD and smoking are both associated with the development of metabolic features,there has been increasing interest in testing the relationship between smoking and *** causal relevance of smoking to NAFLD incidence have been implicated in crosssectional and prospective cohort studies.3,4 However,previous studies mainly focused on the effect of active smoking,discussion on the influence of passive smoking on NAFLD will facilitate illustrating the association between smoking and *** conducted a national two-center cross-section study of active,passive smoking and NAFLD risk in Chinese and European *** design allowed us to(1)test for associations between active,passive smoking and NAFLD risk by sex and consolidate evidence for causality by estimating dose-response relationship,(2)identify mediated factors,and(3)resolve their possible interaction with smoking.

关键词： mortality cardiovascular passive

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Enhancing visible-light-driven NO oxidation through molecular‐level insights of dye-loaded sea sands

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Rare Metals 2024年第2期43卷 543-554页

作者： Yu-Han Li Bang-fu Chen Sónia A.C.Carabineiro You-Yu Duan Ping Tan Wing-Kei Ho Fan Dong Engineering Research Center for Waste Oil Recovery Technology and Equipment Ministry of EducationChongqing Key Laboratory of Catalysis and New Environmental MaterialsChongqing Technology and Business UniversityChongqing400067China Nanchang Institute of Technology Nanchang33044China LAQV-REQUIMTE Department of ChemistryNOVA School of Science and TechnologyUniversidade NOVA de Lisboa2829-516CaparicaPortugal College of Physics and Center of Quantum Materials and Devices Chongqing UniversityChongqing401331China Department of Science and Environmental Studies The Education University of Hong KongHong Kong999077China

Natural minerals,abundant and easily obtained through simple physical processing,offer a cost-effective and environmentally friendly solution for dyeing wastewater disposal and air pollution *** study investigates the photocatalytic removal of NO using natural different types of dyes,loaded on natural sand,under visible light *** examining various coating concentrations of dyes and sand weights,we discovered that sand loaded with Rhodamine B(RhB)exhibits high activity for the photo-oxidation of NO.A combination results of X-ray diffraction(XRD),X-ray photoelectron spectroscopy(XPS),Fourier transform infrared spectroscopy(FTIR)and thermogravimetric(TG)analyses confirm the presence of SiO_(2),CaCO_(3),Al_(2)O_(3)and iron oxides as the main components of the ***,studying RhB-loaded individual components reveals that CaCO_(3)plays a crucial role in enhancing the NO removal *** results and theoretical calculations demonstrate the establishment of a directional charge transfer channel from CaCO_(3)to RhB,facilitating the adsorption and activation of molecular NO and O_(2).This work not only promotes the utilization of natural mineral resources but also enriches the fields of environmental photochemistry and semiconductor photocatalysis.

关键词： Sand dyes Rhodamine B Photo-oxidation of NO Visible light illumination

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Recursive filtering of multi-rate cyber-physical systems with unknown inputs under adaptive event-triggered mechanisms

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Frontiers of Information Technology & Electronic Engineering 2024年第2期25卷 250-259页

作者： ying SUN Miaomiao fu Jingyang MAO Guoliang WEI Business School University of Shanghai for Science and TechnologyShanghai200093China Shanghai Caoyang Vocational School Shanghai200333China School of Electrical and Electronic Engineering Shanghai Institute of TechnologyShanghai201418China School of Intelligent Emergency Management University of Shanghai for Science and TechnologyShanghai200093China

Cyber-physical systems(CPSs)take on the characteristics of both multiple rates of information collection and processing and the dependency on information *** purpose of this paper is to develop a joint recursive filtering scheme that estimates both unknown inputs and system states for multi-rate CPSs with unknown *** cyberspace,the information transmission between the local joint filter and the sensors is governed by an adaptive event-triggered ***,the desired parameters of joint filters are determined by a set of algebraic matrix equations in a recursive way,and a sufficient condition verifying the boundedness of filtering error covariance is found by resorting to some algebraic operation.A state fusion estimation scheme that uses local state estimation is proposed based on the covariance intersection(ci)based fusion ***,an illustrative example demonstrates the effectiveness of the proposed adaptive event-triggered recursive filtering algorithm.

关键词： Cyber-physical systems Multi-rate Joint recursive filtering Adaptive event-triggered mechanisms Unknown inputs

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Efficacy and safety of remimazolam in bronchoscopic sedation:A meta-analysis

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World Journal of Clinical Cases 2024年第6期12卷 1120-1129页

作者： ying Zhou Cheng Zhao yi-Xun Tang Ji-Tong Liu Department of Anesthesiology The First Affiliated Hospital of Hunan Normal University(Hunan Provincial People’s Hospital)Changsha 410005Hunan ProvinceChina Department of Anesthesiology Zhangjiajie People's HospitalZhangjiajie 427000Hunan ProvinceChina

BACKGROUND Remimazolam is a new benzodiazepine used for procedural sedation and general *** studies have used remimazolam for bendable *** To assess the safety and efficacy of remimazolam for sedation in patients undergoing bendable bronchoscopy by performing a meta-analysis of randomized controlled trials(RCTs).METHODS We searched the EMBASE,PubMed,Cochrane Library,and Web of Science databases for RCTs on bendable bronchoscopic procedural sedation with remimazolam vs conventional sedatives(CS).RESULTS Five studies with 1080 cases were *** had the same sedation success rate compared with CS[relative risk(RR):1.35,95%ci:0.60-3.05,P=0.474,I2=99.6%].However,remimazolam was associated with a lower incidence of hypotension(RR:0.61;95%ci:0.40-0.95,P=0.027;I2=65.1%)and a lower incidence of respiratory depression(RR:0.50,95%ci:0.33-0.77,P=0.002,I2=42.3%).A subgroup analysis showed a higher success rate of sedation with remimazolam than midazolam(RR:2.45,95%ci:1.76-3.42,Pcidence of hypotension(RR:0.45,95%ci:0.32-0.64,Pci:0.30-0.76,P=0.002,I2=78.4%),hypoxemia(RR:0.36,95%ci:0.15-0.87,P=0.023),and injection pain(RR:0.04,95%ci:0.01-0.28,P=0.001)were *** Remimazolam is safe and effective during *** sedation success rate was similar to that in the CS ***,remimazolam has a higher safety profile,with fewer inhibitory effects on respiration and circulation.

关键词： Remimazolam Bronchoscopy Procedural sedation Meta-analysis

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