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Non-tax Revenue and Local Economic Growth --The Case of Taiwan

经济管理学刊（中英文版） 2015年第1期4卷 8-14页

作者： Hsiu-Wei Chang yi-chung hsu Department of Public Finance and Taxation National Taichung University of Science and Technology Taichung Taiwan

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The evolutionarily diverged single-stranded DNA-binding proteins SSB1/SSB2 differentially affect the replication,recombination and mutation of organellar genomes in Arabidopsis thaliana

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Plant Diversity 2025年第1期47卷 127-135页

作者： Weidong Zhu Jie Qian yingke Hou Luke R.Tembrock Liyun Nie yi-Feng hsu Yong Xiang yi Zou Zhiqiang Wu Shenzhen Branch Guangdong Laboratory of Lingnan Modern AgricultureKey Laboratory of Synthetic BiologyMinistry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518120China Guangdong Laboratory for Lingnan Modern Agriculture College of Life SciencesSouth China Agricultural UniversityGuangzhou 510642China School of Life Sciences Southwest UniversityChongqing 400715China Department of Biology Colorado State UniversityFort CollinsCO 80523USA School of Medical Molecular and Forensic SciencesMurdoch UniversityMurdochWA 6149Australia State Key Laboratory of Crop Stress Adaptation and Improvement School of Life SciencesHenan UniversityKaifeng 475004China Shenzhen Research Institute of Henan University Shenzhen 518000China

Single-stranded DNA-binding proteins(SSBs)play essential roles in the replication,recombination and repair processes of organellar DNA *** Arabidopsis thaliana,SSBs are encoded by a small family of two genes(SSB1 and SSB2).However,the functional divergence of these two SSB copies in plants remains largely unknown,and detailed studies regarding their roles in the replication and recombination of organellar genomes are still *** this study,phylogenetic,gene structure and protein motif analyses all suggested that SSB1 and SSB2 probably diverged during the early evolution of seed *** on accurate long-read sequencing results,ssb1 and ssb2 mutants had decreased copy numbers for both mitochondrial DNA(mtDNA)and plastid DNA(ptDNA),accompanied by a slight increase in structural rearrangements mediated by intermediate-sized repeats in mt genome and small-scale variants in both *** findings provide an important foundation for further investigating the effects of DNA dosage in the regulation of mutation frequencies in plant organellar genomes.

关键词： SSB Organellar genomes Replication Recombination Mutation

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Methylprednisolone Inhibits the Expression of Glial Fibrillary Acidic Protein and Chondroitin Sulfate Proteoglycans in Reactivated Astrocytes

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神经损伤与功能重建 2008年第5期3卷 342-351,356页

作者： WEI-LIN LIU yi-hsuAN LEE SHIH-yiNG TSAI chung yi hsu YU-YO SUN LIANG-YO YANG SHING-HAN TSAI AND WEI-chung VIVIAN YANG Graduate Institute of Biomedical Materials and Engineering Taipei Medical University Taipei Taiwan Graduate Institute of Neuroscience College of Medicine Taipei Medical Uni- versity Taipei Taiwan Division of Physiology and Neuroscience Graduate Institute of Medi- cal Sciences College of Medicine Taipei Medical University Taipei Taiwan Department of Physiology School of Medicine College of Medicine Taipei Medical University Taipei Tai- wan Graduate Institute of Injury Prevention and Control Taipei Medical University Taipei Taiwan Department of Neurosurgery Taipei Municipal WanFang Hospital Taipei Taiwan

创伤后的神经胶质增生导致硫酸软骨素蛋白聚糖(CSPG)的显著表达,从而抑制轴突生长和再生。甲基强地松龙(MP),一种合成的糖皮质激素,在急性脊髓损伤(SCI)的治疗中有神经保护作用和抗炎效应。但是,MP对于CSPG在活性胶质细胞中的表达的作... 详细信息

创伤后的神经胶质增生导致硫酸软骨素蛋白聚糖(CSPG)的显著表达,从而抑制轴突生长和再生。甲基强地松龙(MP),一种合成的糖皮质激素,在急性脊髓损伤(SCI)的治疗中有神经保护作用和抗炎效应。但是,MP对于CSPG在活性胶质细胞中的表达的作用尚不清楚。本文用a-氨基-3-羟基-5-甲基-4-异恶唑丙酸酯(AM-PA)诱导星形胶质细胞再活化,用环噻嗪模拟SCI的兴奋性中毒刺激。AMPA治疗后,星形胶质细胞再活化的标志物-胶质纤维酸性蛋白(GFAP)、CSPG神经聚糖和磷酸盐的表达都显著上调。AMPA治疗星形胶质细胞的条件培养液强烈抑制大鼠背根神经节中神经元的轴突生长,但这种作用能被MP的预处理所逆转。此外,MP下调成年SCI大鼠中GFAP和CSPG的表达,对抗RU486的糖皮质激素受体(GR)和GR si RNA能逆转MP对GFAP和神经聚糖表达的抑制作用。这些结果提示,MP能在兴奋性中毒损伤后通过GR介导的星形胶质细胞再活化下调和GSPG表达抑制来改善神经修复,促进轴突生长。

关键词：中枢神经系统硫酸软骨素蛋白聚糖神经胶质增生糖皮质激素脊髓损伤

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Success of intravenous immunoglobulin and steroids in managing severe COVID-19 following lung transplantation:A case report

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World Journal of Transplantation 2025年第1期15卷 178-184页

作者： Yen-Shou Kuo Kuan-hsun Lin ying-yi Chen Yuan-Ming Tsai Ti-Hui Wu hsu-Kai Huang Tsai-Wang Huang Division of Thoracic Surgery Department of SurgeryTri-Service General HospitalNational Defense Medical CenterTaipei 114202Taiwan

BACKGROUND Coronavirus disease 2019(COVID-19)pneumonia with severe septic shock and acute respiratory distress syndrome(ARDS)are critical illnesses for patients following *** immunoglobulin(IVIG)plays a role in both immune support and inflammation control,especially in immunocompromised *** case report describes the first successful experience using IVIG and pulse steroids to manage this critical condition following lung *** SUMMARY A 65-year-old male patient reported a history of chronic obstructive pulmonary disease and poor lung function and received bilateral sequential lung ***,he developed COVID-19 pneumonia,severe septic shock,and *** recovered from this critical condition after empirical antibiotics administration and veno-venous extracorporeal membrane oxygenation,in addition to IVIG and pulse *** IVIG is a valuable adjunct in managing severe sepsis in lung transplant recipients after COVID-19 *** aim,for the first time,to report the success of such a management approach for COVID-19 ARDS and sepsis in the post-lung transplant *** further investigations,this is a starting point for wider analysis of such an approach in this setting and consequently helps guide clinical practice for such a challenging patient population moving forward.

关键词： COVID-19 Septic shock Intravenous immunoglobulin Lung transplantation Post-transplant complications Case report

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Microplastic and nanoplastic exposure and risk of diabetes mellitus

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World Journal of Clinical Cases 2025年第3期13卷 24-29页

作者： Hui-yi Hsiao chung-yi Nien Ruei-Feng Shiu Wei-Chun Chin Tzung-Hai Yen Department of Biomedical Sciences College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina Center for Tissue Engineering Chang Gung Memorial HospitalLinkouTaoyuan 33305TaiwanChina Department of Life Sciences National Central UniversityZhongli 320317TaoyuanTaiwanChina Center of Excellence for The Oceans Taiwan Ocean UniversityKeelung 20224TaiwanChina Institute of Marine Environment and Ecology Taiwan Ocean UniversityKeelung 20224TaiwanChina Department of Chemical and Materials Engineering University of California MercedMercedCA 95343United States Department of Nephrology Clinical Poison CenterChang Gung Memorial HospitalLinkou 33305TaoyuanTaiwanChina School of Traditional Chinese Medicine College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina

The issue of plastic pollutants has become a growing *** microplastics(MPs)(particle size<5 mm)and nanoplastics(NPs)(particle size<1μm)can cause DNA damage,cytotoxicity,and oxidative stress in various *** primary known impacts of microplastic/nanoplastic are observed in the liver and respiratory system,leading to hepatotoxicity and chronic obstructive pulmonary *** research on the effects of MPs and NPs on diabetes is still in its early stages,there are potential *** editorial highlights the risk to diabetics from co-exposure to contaminants and MPs/NPs,supported by evidence from animal studies and the various chemical compositions of MPs/NPs.

关键词： Microplastics Nanoplastics Plastic pollution,Diabetes mellitus Insulin resistance

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Crystallization Modulation and Holistic Passivation Enables Efficient Two‑Terminal Perovskite/CuIn(Ga)Se_(2)Tandem Solar Cells

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Nano-Micro Letters 2025年第1期17卷 205-215页

作者： Cong Geng Kuanxiang Zhang Changhua Wang chung Hsien Wu Jiwen Jiang Fei Long Liyuan Han Qifeng Han yi‑Bing Cheng Yong Peng State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070People’s Republic of China Triumph Photovoltaic Materials Co. Ltd.No.1001 Yannan AvenueHigh‑Tech Development DistrictBengbuAnhui 233000People’s Republic of China College of Materials Science and Engineering Guilin University of TechnologyGuilin 541004People’s Republic of China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Two-terminal(2-T)perovskite(PVK)/CuIn(Ga)Se_(2)(CIGS)tandem solar cells(TSCs)have been considered as an ideal tandem cell because of their best bandgap matching regarding to Shockley–Queisser(S–Q)***,the nature of the irregular rough morphology of commercial CIGS prevents people from improving tandem device *** this paper,D-homoserine lactone hydrochloride is proven to improve coverage of PVK materials on irregular rough CIGS surfaces and also passivate bulk defects by modulating the growth of PVK *** addition,the minority carriers near the PVK/C60 interface and the incompletely passivated trap states caused interface recombination.A surface reconstruction with 2-thiopheneethylammonium iodide and N,N-dimethylformamide assisted passivates the defect sites located at the surface and grain ***,LiF is used to create this field effect,repelling hole carriers away from the PVK and C60 interface and thus reducing *** a result,a 2-T PVK/CIGS tandem yielded a power conversion efficiency of 24.6%(0.16 cm^(2)),one of the highest results for 2-T PVK/CIGS TSCs to our *** validation underscores the potential of our methodology in achieving superior performance in PVK/CIGS tandem solar cells.

关键词： PVK/CIGS TSCs Irregular rough surfaces Modulating the growth PVK/C60 interface recombination

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Erosion control for mudstone soil with ventilation and watertight resin

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International Journal of Sediment Research 2010年第2期25卷 194-201页

作者： chung-li hsu Shin-yi DAI Shiu-wen CHIANG Department of Soil and Water Conservation National Pingtung University of Science and Technology Graduate Institute of Disaster Prevention on Hillslopes and Water Resources Engineering National Pingtung University of Science and Technology

To accelerate the re-vegetation of exposed landslide areas, hydroseeding for soil and water conservation has been widely applied as one of the economically feasible ways. However, effect durations of different hydroseeding materials are different, the formulation density has a certain effect on plant growth and the addictives may exude. This paper presents laboratory experiments of soil erosion, exuding water quality and soil hardness by using a rainfall simulator with different conditions of slope, rainfall intensity and medication density. The results showed that soil erosion decreased significantly, suggesting a good erosion-resisting effect by the ventilation and watertight resin. No significant variation of the exuded water was observed during testing, which indicates that after gelling, the ventilation and watertight resin are unlikely to release chemical substances. It was found that high resin density will result in poor workability as well as high costs; adverse will cause the mudstone to fracture due to raindrops since cracks are common to soil surface. The weatherability after spraying and its effect on plant vegetation still need further investigation.

关键词： Ventilation and watertight resin Hydro seeding Mudstone Soil erosion Rainfall simulator

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Prognostic factors of short-term outcomes of intravitreal ranibizumab in diabetic macular edema

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International Journal of Ophthalmology(English edition) 2017年第5期10卷 765-771页

作者： I-An Lai Wei-Cherng hsu chung-May Yang yi-Ting Hsieh Department of Ophthalmology Taipei Tzu Chi HospitalBuddhist Tzu Chi Medical Foundation New Taipei 231Taiwan China School of Medicine Tzu Chi University Hualien 970 Taiwan Department of Ophthalmology National Taiwan University Hospital Taipei 10002 Taiwan China

AIM：To evaluate the prognostic factors for short-term visual and anatomical improvement of intravitreal ranibizumab（IVR） for diabetic macular edema（DME）.METHODS：Fifty-one eyes from 35 patients that received three consecutive monthly IVR for DME with moderate visual loss were retrospectively recruited; all cases had their baseline best-corrected visual acuity（BCVA） between 20/400 and 20/40. BCVA and central subfield thickness（CST） at baseline and month 3 were collected. Linear mixed models were used to evaluate the prognostic factors for visual and anatomical improvement at month ***：Younger age, poorer baseline BCVA and proliferative diabetic retinopathy（PDR） were correlated with better visual improvement at month 3（P=0.002, 0.0001 and 0.007, respectively）. Thicker CST and the presence of subretinal fluid at baseline were correlated with a greater reduction in CST（P〈0.0001 and P=0.018, respectively）. The presence of epiretinal membrane or previous posterior subtenon injection of triamcinolone acetonide（PSTA） were associated with a smaller reduction in CST（P=0.029 and 0.018, respectively）, but had no significant effects in visual improvement at month 3（P〉0.05 for both）.CONCLUSION：For eyes with DME and moderate visual loss, those with younger age, poorer baseline BCVA or PDR tend to have better visual improvement after three consecutive monthly IVR. Epiretinal membrane or previous PSTA result in less resolution of CST, but do not significantly affect visual improvement.

关键词： diabetic macular edema anti-vascular endothelial growth factor ranibizumab diabetic retinopathy epiretinal membrane

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Capacitive sensing technique for silt suspended sediment concentration monitoring

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International Journal of Sediment Research 2010年第2期25卷 175-184页

作者： yin-Sung hsu Shih-yi YUAN Chia-Ling CHANG Kao-chung CHANG Feng Chia University Division Chief of Water Resources Agency Ministry of Economic Affairs

Automated, real-time, and continuous techniques for monitoring suspended sediment concentration in rivers and reservoirs can play an important role in the improvement of the quantity and quality of sediment data, and are valuable to the management of water environment, water conservancy, hazard prevention, and water resources. Research in the monitoring techniques has examined the possibility of using the characteristics of dielectric constants for detecting soil moisture and concentration of air-water two-phase flow, based on the fact that dielectric constants of sediment, air and water are different. A capacitance sensor was developed to monitor the silt suspended sediment concentration (SSSC) in a recent study, following the principle that as SSSC increases in the sediment-water mixture, the apparent dielectric constant of the water sample also increases and therefore the capacitance detected by the sensing system also increases. It is demonstrated that the variations in the concentration of silt sediment correlates positively with the variations in observed capacitance in a linear fashion, and correlates negatively with voltage outputs but also in a linear fashion. The correlation coefficients reached above 0.98. The overall errors in estimated concentrations range between 0.26% and 2.91%. Elements in the capacitance sensor system such as the frequencies of the signal generating system, areas of the electrode plates, and effects of sample temperature have also been evaluated. The results illustrated that the capacitance sensor techniques can be applied to monitoring SSSC automatically and continuously. Also, the range of SSSC in the experiment reached 200 kg/m3; therefore, the application of this technique in practical SSSC monitoring is worthy of further research.

关键词： Silt suspended sediment concentration Sediment sampling Automated continuous measurement Capacitive sensing system Dielectric material Silt sediment

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A new weir surface repair layer with shock absorbing cushion design

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Earthquake Engineering and Engineering Vibration 2013年第3期12卷 487-496页

作者： Tse-Shan hsu yi-Lang Hsieh Department of Civil Engineering Feng-Chia University Ph.D Program in Civil and Hydraulic Engineering Feng-Chia University

A shock absorbing cushion has never been introduced into any traditional weir surface repair layer design. However, shocks induced by high discharge with heavy sediment can easily produce brittle fracture and peeling over a weir surthce repair layer as it is impacted by floods accompanied by particles of different sizes. In this study, transcending traditional designs, the authors developed a composite unit designed with a shock absorbing cushion that has performed well during field tests, proving that the weir body can be effectively protected even if the composite units are directly laid on a severely uneven weir surface repair layer.

关键词： shock absorbing cushion brittle fracture peeling weir

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