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Lunar cratering asymmetries with high lunar orbital obliquity and inclination of the Moon

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Research in Astronomy and Astrophysics 2021年第6期21卷 281-293页

作者： Hua-Cheng Li Nan Zhang Zong-yu yue Yi-zhuo Zhang Key Laboratory of Orogenic Belts and Crustal Evolution School of Earth and Space SciencesPeking UniversityBeijing 100871China Earth Dynamics Research Group School of Earth and Planetary SciencesCurtin University6102 WAAustralia State Key Laboratory of Remote Sensing Science Aerospace Information Research InstituteChinese Academy of SciencesBeijing 100101China

Accurate estimation of cratering asymmetry on the Moon is crucial for understanding Moon evolution *** studies of cratering asymmetry have omitted the contributions of high lunar obliquity and ***,we include lunar obliquity and inclination as new controlling variables to derive the cratering rate spatial variation as a function of longitude and *** examining the influence of lunar obliquity and inclination on the asteroids population encountered by the Moon,we then have derived general formulas of the cratering rate spatial variation based on the crater scaling *** formulas with addition of lunar obliquity and inclination can reproduce the lunar cratering rate asymmetry at the current Earth-Moon distance and predict the apex/ant-apex ratio and the pole/equator ratio of this lunar cratering rate to be 1.36 and 0.87,*** apex/ant-apex ratio is decreasing as the obliquity and inclination *** with the evolution of lunar obliquity and inclination,our model shows that the apex/ant-apex ratio does not monotonically decrease with Earth-Moon distance and hence the influences of obliquity and inclination are not negligible on evolution of apex/ant-apex *** model is generalizable to other planets and moons,especially for different spin-orbit resonances.

关键词： Moon meteorites meteors meteoroids planets and satellites:surfaces

Texture and anisotropy of hot-pressed h-BN matrix composite ceramics with in situ formed YAG

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Journal of Advanced Ceramics 2022年第4期11卷 532-544页

作者： zhuo ZHANG Xiaoming DUAN zhuo TIAN yujin WANG Lan WANG Lei CHEN Baofu QIU Delong CAI Peigang HE Dechang JIA yu ZHOU Key Laboratory of Advanced Structural-Functional Integration Materials&Green Manufacturing Technology Harbin Institute of TechnologyHarbin 150001China Institute for Advanced Ceramics School of Materials Science and EngineeringHarbin Institute of TechnologyHarbin 150001China State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin 150001China School of Electromechanical Engineering Guangdong University of TechnologyGuangzhou 510006China

Textured hexagonal boron nitride(h-BN)matrix composite ceramics were prepared by hotpressing using different contents of 3Y_(2)O_(3)–5Al_(2)O_(3)(molar ratio of 3:5)as the sintering *** hot-pressing,the liquid Y_(3)Al_(5)O_(12)(YAG)phase showing good wettability to h-BN grains was in situ formed through the reaction between Y_(2)O_(3) and Al_(2)O_(3),and a coherent relationship between h-BN and YAG was observed with[010]_(h-BN)//[111]_(YAG) and(002)_(h-BN)//(321)_(YAG).In the YAG liquid phase environment formed during hot-pressing,plate-like h-BN grains were rotated under the uniaxial sintering pressure and preferentially oriented with their basal surfaces perpendicular to the sintering pressure direction,forming textured microstructures with the c-axis of h-BN grains oriented parallel to the sintering pressure direction,which give these composite ceramics anisotropy in their mechanical and thermal *** highest texture degree was found in the specimen with 30 wt%YAG,which also possesses the highest anisotropy degree in thermal *** aggregation of YAG phase was observed in the specimen with 40 wt%YAG,which resulted in the buckling of h-BN plates and significantly reduced the texture degree.

关键词： hexagonal boron nitride(h-BN) liquid phase sintering texture anisotropy

Adaptability of n-γdiscrimination and filtering methods based on plastic scintillation

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Nuclear Science and Techniques 2021年第3期32卷 63-71页

作者： zhuo Zuo Hao-Ran Liu yu-Cheng Yan Bing-Qi Liu Song Zhang Chengdu University of Technology College of Engineering Technology Leshan 614000SichuanChina Southwest Institute of Physics Chengdu 610225China Chengdu University Chengdu 610106China Chengdu University of Technology Chengdu 610225China

Neutrons have been extensively used in many fields,such as nuclear physics,biology,geology,medical science,and national defense,owing to their unique penetration *** rays are usually accompanied by the detection of *** capability to discriminate neutrons from gamma rays is important for evaluating plastic scintillator neutron detectors because similar pulse shapes are generated from both forms of radiation in the detection *** pulse signals measured by plastic scintillators contain noise,which decreases the accuracy of n-y *** improve the performance of n-y discrimination,the noise of the pulse signals should be filtered before the n-y discrimination *** this study,the influences of the Fourier transform,wavelet transform,moving-average filter,and Kalman algorithm on the charge comparison method,fractal spectrum method,and back-propagation neural network methods were *** was found that the Fourier transform filtering algorithm exhibits better adaptability to the charge comparison method than others,with an increasing accuracy of 6.87%compared to that without the filtering ***,the Kalman filter offers an improvement of 3.04%over the fractal spectrum method,and the adaptability of the moving-average filter in backpropagation neural network discrimination is better than that in other methods,with an increase in 8.48%.The Kalman filtering algorithm has a significant impact on the peak value of the pulse,reaching 4.49%,and it has an insignificant impact on the energy resolution of the spectrum measurement after discrimination.

关键词： Fourier transform Wavelet transform Moving average Kalman filter Charge comparison method Fractal spectrum method Back-propagation neural network

Role of ultrasound in the diagnosis of cervical tuberculous lymphadenitis in children

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World Journal of Pediatrics 2021年第5期17卷 544-550页

作者： Tian-zhuo yu Ying Zhang Wen-Zhi Zhang Gao-Yi Yang Department of Ultrasonography Affiliated Hangzhou Chest Hospital.Zhejiang University School of MedicineChinese and Western Hospital of Zhejiang Province(Hangzhou Red Cross Hospital)No.208 Huancheng East RoadHangzhou 310003China

Background To describe sonographic characteristics of cervical tuberculous lymphadenitis(CTBL)in children,clinical infor-mation,and sonograms of 348 lymph nodes(LNs)from 57 children with CTBL were retrospectively analyzed in this *** We retrospectively reviewed the clinical data and sonograms of 348 LNs from 31 boys and 26 girls with CTBL,who were confirmed by pathology or laboratory examination,at the Hangzhou Red Cross Hospital between June 2014 and December *** age of the children ranged from 1 to 14 years(average 7.1±2.9 years).Results Night sweats,fatigue and loss of appetite were the most common clinical symptoms observed in children with *** LN involvements were *** was found in healthy children with no *** sonography,the hilus was absent or unclear in all *** short-to-long axis(S/L)ratio was 20.5,and the edges were unclear in most *** accompanying findings included necrosis(47.4%),an echogenic thin layer(36.8%),surround-ing soft-tissue edema(38.5%)。multiple intra-nodal strong echo(28.2%),sinus(22.7%)and abscess formation(6.9%).The Doppler ultrasound showed that the majority of vascularity patterns of CTBL were capsular or peripheral(3.3%).Conclusions Ultrasound is a recommended examination method for children from different age groups with cervical *** ultrasonic signs of hilus absence,S/L ratio≥0.5,unclear edge,necrosis,echogenic thin layer,strong echoes and capsular or peripheral vascularity may aid in the diagnosis of cervical tuberculous lymphadenitis.

关键词： Cervical lymphadenitis Children Tuberculosis Ultrasonography

Pressure relief of underground ammunition storage under missile accidental ignition

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Defence Technology（防务技术） 2021年第3期17卷 1081-1093页

作者： Ya-wei Wang yu-zhuo Yang Gao-wan Zou Hui Dong Yan Huo College of Aerospace and Civil Engineering Harbin Engineering UniversityHarbinHeilongjiangChina Architecture and Civil Engineering Department City University of Hong KongHong KongChina

Safety of underground ammunition storage is an important issue,especially during the accidental ignition of *** work investigates the pressure and temperature distribution of the multi-layer underground ammunition storage with a pressure relief duct during the accidental ignition process of the missile.A large-scale experiment was carried out using a multi-layered restricted space with a pressure relief duct to simulate the underground ammunition store and a solid rocket motor to simulate the accidental ignition of the *** results show that when the motor gas mass flow increased by5.6 times,the maximum pressure of the ammunition storage increased by 5.87 *** a certain motor flow rate,when the pressure relief exhaust area at the end of the relief duct was reduced by 1/2,the maximum pressure on the first layer did not *** the rate of pressure relief was reduced and the time delayed for the pressure of ammunition store to drop to *** this experiment,when the motor ignition position was located in to the third layer ammunition chamber,the maximum pressure was reduced by 32.9%and also reduced the rate of change of *** addition,for the experimental conditions,the theoretical analysis of the pressure relief of the ammunition storage is given by a simplified *** on the findings,some suggestions to the safety protection design of ammunition store are proposed.

关键词： Underground ammunition storage Pressure relief Large-scale experiment Missile accidental ignition

Improved Cohen-Sutherland algorithm for TGS transmission imaging

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Nuclear Science and Techniques 2023年第6期34卷 91-102页

作者： yu-Cheng Yan Ming-Zhe Liu Xing-yu Li yu-Ting Xiong Yao Tan zhuo Zuo Lan Chang Cui Li State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of TechnologyChengdu610059China The Engineering and Technical College of Chengdu University of Technology Leshan614000China Southwestern Institute of Physics Chengdu610225China Sichuan University of Science and Engineering Zigong643000China

Tomographic gamma scanner(TGS),an advancedγ-ray nondestructive analysis technique,can locate and analyze nuclides in radioactive nuclear waste,and TGS can be categorized into two processes:e.g.,transmission measurement and emission ***,transmission measurements provide the basis for accurate measurement of nonuniform radionuclide content in TGS *** scan data were obtained using the Monte Carlo tool Geant4 simulation,and 25 voxels were divided into five lengths and five widths in a square *** this study,an encoding cropping algorithm based on draped foot vector judgment was adopted to rapidly calculate the voxel trace matrix within a square bucket of nuclear waste,and the transmission images were reconstructed using ordered subset expectation *** results indicated that the cropping speed of the improved coding algorithm was significantly higher than that of the original algorithm,and the relative mean deviation and root-mean-square error between the reconstructed attenuation coefficient and the reference standard value tended to decrease with an increase in the cropped line segments in the voxel;the Pearson correlation coefficient tended to converge to *** image quality evaluation parameters of the high media-density materials were better than those of the low media-density materials in the above three *** reconstruction effect was relatively poor for more complex filling *** there were more than 10 cropped line segments in the voxel,the reconstruction data generally tended to be *** graphical trimming algorithm can rapidly calculate the trace matrix of the scanned voxels;it exhibits the advantages of speed and efficiency and can serve as a novel method to solve the trace matrix of TGS nuclear waste transmission scans.

关键词： TGS Cohen-Sutherland Transmission scanning Trace matrix

Developing risk models and subtypes of autophagy-associated LncRNAs for enhanced prognostic prediction and precision in therapeutic approaches for liver cancer patients

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Oncology Research 2024年第4期32卷 703-716页

作者： LU ZHANG JINGUO chu yuSHAN yu Department of General Practice The First Affiliated Hospital of Ningbo UniversityNingboChina

Background:Limited research has been conducted on the influence of autophagy-associated long non-coding RNAs(ARLncRNAs)on the prognosis of hepatocellular carcinoma(HCC).Methods:We analyzed 371 HCC samples from TCGA,identifying expression networks of ARLncRNAs using autophagy-related *** for prognostically relevant ARLncRNAs involved univariate Cox regression,Lasso regression,and multivariate Cox regression.A Nomogram was further employed to assess the reliability of Riskscore,calculated from the signatures of screened ARLncRNAs,in predicting ***,we compared drug sensitivities in patient groups with differing risk levels and investigated potential biological pathways through enrichment analysis,using consensus clustering to identify subgroups related to ***:The screening process identified 27 ARLncRNAs,with 13 being associated with HCC ***,a set of signatures comprising 8 ARLncRNAs was successfully constructed as independent prognostic factors for *** in the high-risk group showed very poor prognoses in most clinical *** Riskscore was closely related to immune cell scores,such as macrophages,and the DEGs between different groups were implicated in metabolism,cell cycle,and mitotic ***,high-risk group patients demonstrated a significantly lower IC50 for Paclitaxel,suggesting that Paclitaxel could be an ideal treatment for those at elevated risk for *** further identified C2 as the Paclitaxel subtype,where patients exhibited higher Riskscores,reduced survival rates,and more severe clinical ***:The 8 signatures based on ARLncRNAs present novel targets for prognostic prediction in *** drug candidate Paclitaxel may effectively treat HCC by impacting ARLncRNAs *** the identification of ARLncRNAsrelated isoforms,these results provide valuable insights for clinical exploration of autophagy mechanisms in HCC pathogenesis and offer potential av

关键词： Autophagy Hepatocellular carcinoma(HCC) Prognosis Precision medicine Paclitaxel

A cyclodextrin-based nanoformulation achieves co-delivery of ginsenoside Rg3 and quercetin for chemo-immunotherapy in colorectal cancer

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Acta Pharmaceutica Sinica B 2022年第1期12卷 378-393页

作者： Dandan Sun Yifang Zou Liu Song Shulan Han Hao Yang Di chu yun Dai Jie Ma Caitriona M.O’Driscoll zhuo yu Jianfeng Guo School of Pharmaceutical Sciences Jilin UniversityChangchun 130021China Laboratory of Cancer Precision Medicine The First Hospital of Jilin UniversityChangchun 130021China Pharmacodelivery Group School of PharmacyUniversity College CorkCork T12 YT20Ireland Department of Hepatopathy Shuguang HospitalAffiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China

The immune checkpoint blockade therapy has profoundly revolutionized the field of cancer immunotherapy. However, despite great promise for a variety of cancers, the efficacy of immune checkpoint inhibitors is still low in colorectal cancer(CRC). This is mainly due to the immunosuppressive feature of the tumor microenvironment(TME). Emerging evidence reveals that certain chemotherapeutic drugs induce immunogenic cell death(ICD), demonstrating great potential for remodeling the immunosuppressive TME. In this study, the potential of ginsenoside Rg3(Rg3) as an ICD inducer against CRC cells was confirmed using in vitro and in vivo experimental approaches. The ICD efficacy of Rg3 could be significantly enhanced by quercetin(QTN) that elicited reactive oxygen species(ROS). To amelioratein vivo delivery barriers associated with chemotherapeutic drugs, a folate(FA)-targeted polyethylene glycol(PEG)-modified amphiphilic cyclodextrin nanoparticle(NP) was developed for co-encapsulation of Rg3 and QTN. The resultant nanoformulation(***) significantly prolonged blood circulation and enhanced tumor targeting in an orthotopic CRC mouse model, resulting in the conversion of immunosuppressive TME. Furthermore, the *** achieved significantly longer survival of animals in combination with Anti-PD-L1. The study provides a promising strategy for the treatment of CRC.

关键词： Nano drug delivery system Chemotherapy Immunotherapy Combination therapy Immunogenic cell death Reactive oxygen species Tumor microenvironment Colorectal cancer

Magnetic Transport Properties of Fe-Phthalocyanine Dimer with Carbon Nanotube Electrodes

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Chinese Physics Letters 2017年第4期34卷 79-82页

作者： yu-zhuo Lv Peng Zhao De-Sheng Liu School of Physics and Technology University of Jinan Jinan 250022 School of Physics Shandong University Jinan 250100 Department of Physics Jining University Qufu 273155

Based on the non-equilibrium Green＇s method and density functional theory, the magnetic transport of Fe- phthMocyanine dimers with two armchair single-wailed carbon nanotube electrodes is investigated. The results show that the system can present high-performance spin filtering, magnetoresistance, and low-bias spin negative differential resistance effects by tuning the external magnetic field. These results show that the Fe-phthalocyanine dimer has the potential to design future molecular spintronic devices.

关键词： Magnetic Transport Properties of Fe-Phthalocyanine Dimer with Carbon Nanotube Electrodes Fe AP NDR CSR