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Open Journal of Gastroenterology 2024年第8期14卷 261-266页

作者： peter Cassar Nicholas Delicata Department of Medicine Department of Nephrology and General Medicine Mater Dei Hospital Msida Malta Department of Medicine Department of Gastroenterology Mater Dei Hospital Msida Malta

This case report sheds light on a curious case of rhabdomyolysis in an otherwise healthy twenty-eight-year-old male and its direct effect on liver function tests. This case report provides a fresh perspective on the doctor-patient dynamic where a medic becomes a doctor. Attention is also drawn to the mental and socioeconomic repercussions of having a health issue whilst applying for a home loan.

关键词： Rhabdomyolysis Transaminase Creatinine Kinase

High-Performance and Large-Area Inverted Perovskite Solar Cells Based on NiO_(x) Films Enabled with A Novel Microstructure-Control Technology

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Energy & Environmental Materials 2024年第1期7卷 153-159页

作者： Guibin Shen Xin Li Yuqin Zou Hongye Dong Dongping Zhu Yanglin Jiang Xin Ren Ng Fen Lin peter Müller-Buschbaum Cheng Mu Key Laboratory of Advanced Light Conversion Materials and Biophotonics Department of ChemistryRenmin University of ChinaBeijing 100872China Solar Energy Research Institute of Singapore(SERIS) National University of SingaporeSingapore 117574Singapore Physik-Department Lehrstuhl für Funktionelle MaterialienTechnische Universität MünchenJames-Franck-Straße 185748Garching Germany Heinz Maier-Leibnitz Zentrum(MLZ) Technische Universität MünchenLichtenbergstr.185748Garching Germany

The improvement in the efficiency of inverted perovskite solar cells(PSCs)is significantly limited by undesirable contact at the NiO_(x)/perovskite *** this study,a novel microstructure-control technology is proposed for fabrication of porous NiO_(x)films using Pluronic P123 as the structure-directing agent and acetylacetone(AcAc)as the coordination *** synthesized porous NiO_(x)films enhanced the hole extraction efficiency and reduced recombination defects at the NiO_(x)/perovskite ***,without any modification,the power conversion efficiency(PCE)of the PSC with MAPbl_(3)as the absorber layer improved from 16.50%to 19.08%.Moreover,the PCE of the device composed of perovskite Cs0.05(MA_(0.15)FA_(0.85))_(0.95)Pb(I_(0.85)Br_(0.15))_(3)improved from 17.49%to 21.42%.Furthermore,the application of the fabricated porous NiO_(x)on fluorine-doped tin oxide(FTO)substrates enabled the fabrication of large-area PSCs(1.2 cm^(2))with a PCE of 19.63%.This study provides a novel strategy for improving the contact at the NiO_(x)/perovskite interface for the fabrication of high-performance large-area perovskite solar cells.

关键词： interfacial contact inverted and large-area perovskite solar cells photovoltaic materials porous NiO_(x)films renewable energy

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Script-Based GPU-Ready ELM Development for Continuous Code Integration

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Journal of Computer and Communications 2024年第5期12卷 102-106页

作者： peter Schwartz Dali Wang Fengming Yuan peter Thornton Oak Ridge National Laboratory Environmental Sciences Division Oak Ridge USA

Designing and optimizing complex scientific code for new computing architectures is a challenging task. To address this issue in the E3SM land model (ELM) development, we developed a software tool called SPEL, which facilitates code generation, verification, and performance tuning using compiler directives within a Function Unit Test framework. In this paper, we present a SPEL extension that leverages the version control system (e.g., Git) to autonomous code generation and demonstrate its application to continuous code integration and development of the ELM software system. The study can benefit the scientific software development community.

关键词： E3SM Land Model GPU Code Porting Continuous Code Integration SPEL Scientific Software Refactorization

Impact of cancer diagnosis on life expectancy by area-level socioeconomic groups in New South Wales, Australia: a population-based study

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Cancer Biology & Medicine 2024年第8期21卷 692-702页

作者： Md Mijanur Rahman Michael David David Goldsbury Karen Canfell Kou Kou Paramita Dasgupta peter Baade Xue Qin Yu The Daffodil Centre The University of SydneyA Joint Venture with Cancer Council NSWSydneyNSW 1340Australia School of Medicine and Dentistry Griffith UniversityGold CoastQLD 4222Australia Cancer Council Queensland BrisbaneQLD 4006Australia

Objective: Improvement in cancer survival over recent decades has not been accompanied by a narrowing of socioeconomic disparities. This study aimed to quantify the loss of life expectancy(LOLE) resulting from a cancer diagnosis and examine disparities in LOLE based on area-level socioeconomic status(SES).Methods: Data were collected for all people between 50 and 89 years of age who were diagnosed with cancer, registered in the NSW Cancer Registry between 2001 and 2019, and underwent mortality follow-up evaluations until December 2020. Flexible parametric survival models were fitted to estimate the LOLE by gender and area-level SES for 12 common ***: Of 422,680 people with cancer, 24% and 18% lived in the most and least disadvantaged areas, respectively. Patients from the most disadvantaged areas had a significantly greater average LOLE than patients from the least disadvantaged areas for cancers with high survival rates, including prostate [2.9 years(95% CI: 2.5±3.2 years) vs. 1.6 years(95% CI: 1.3±1.9 years)] and breast cancer [1.6 years(95% CI: 1.4±1.8 years) vs. 1.2 years(95% CI: 1.0±1.4 years)]. The highest average LOLE occurred in males residing in the most disadvantaged areas with pancreatic [16.5 years(95% CI: 16.1±16.8 years) vs. 16.2 years(95% CI: 15.7±16.7 years)] and liver cancer [15.5 years(95% CI: 15.0±16.0 years) vs. 14.7 years(95% CI: 14.0±15.5 years)]. Females residing in the least disadvantaged areas with thyroid cancer [0.9 years(95% CI: 0.4±1.4 years) vs. 0.6 years(95% CI: 0.2±1.0 years)] or melanoma [0.9 years(95% CI: 0.8±1.1 years) vs. 0.7 years(95% CI: 0.5±0.8 years)] had the lowest average ***: Patients from the most disadvantaged areas had the highest LOLE with SES-based differences greatest for patients diagnosed with cancer at an early stage or cancers with higher survival rates, suggesting the need to prioritise early detection and reduce treatment-related barriers and survivorship challenges to improve life expec

关键词： Cancer diagnosis life expectancy loss of life expectancy area-level socioeconomic status flexible parametric model

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基于模拟-建模研究化学与温度对难熔高熵合金力学行为和变形机制的影响

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Acta Mechanica Sinica 2024年第2期40卷 103-115页

作者：李甲任思危刘彬 peter K.Liaw 方棋洪 State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body College of Mechanical and Vehicle EngineeringHunan UniversityChangsha410082China State Key Laboratory of Powder Metallurgy Central South UniversityChangsha410083China Department of Materials Science and Engineering The University of TennesseeKnoxville37996USA

难熔高熵合金在高温下表现出优异的性能,突破了传统高温合金的工作温度上限.我们采用原子模拟研究了化学元素分布和温度对等原子比MoNbTaW难熔高熵合金变形机制的影响.根据微观结构演化,建立了基于微观结构的本构模型,定量评估多种强化... 详细信息

难熔高熵合金在高温下表现出优异的性能,突破了传统高温合金的工作温度上限.我们采用原子模拟研究了化学元素分布和温度对等原子比MoNbTaW难熔高熵合金变形机制的影响.根据微观结构演化,建立了基于微观结构的本构模型,定量评估多种强化机制的贡献.结果表明,应变硬化后,流动应力随应变呈锯齿状剧烈波动.由于退火结构的溶质浓度降低,温度升高降低了应变硬化率和流动应力波动幅度.变形孪晶在变形机制中起着关键作用,能够通过位错基塑性和晶粒中的非晶形核进一步调节局部变形.有序结构的存在强烈影响了应力和应变分配.固溶强化和晶界强化对流动应力的贡献很大,孪晶强化对流动压力的贡献很小.原子模拟和力学模型为深入理解难熔高熵合金变形行为及性能的精确预测提供依据.

关键词：流动应力固溶强化强化机制高温合金高熵合金变形机制晶界强化溶质浓度

Catatonia:A deep dive into its unfathomable depths

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World Journal of Psychiatry 2024年第2期14卷 210-214页

作者： peter Phiri Gayathri Delanerolle Oliver Hope Tharangini Murugaiyan Geoffrey Dimba Shanaya Rathod Zukiswa Zingela Research&Innovation Department Southern Health NHS Foundation TrustSouthampton SO303JBUnited Kingdom School of Psychology Faculty of Environmental and Life SciencesUniversity of SouthamptonSouthampton SO171BJHampshireUnited Kingdom Acute Inpatients Services Southern Health NHS Foundation TrustBasingstoke RG249RHUnited Kingdom Home Treatment Team South WestSurrey and Borders Partnerships NHS Foundation TrustGuildford GU27XLSurreyUnited Kingdom Faculty of Health Sciences Nelson Mandela UniversitySummerstrand 6001GqeberhaSouth Africa

This editorial addresses catatonia,a complex neuropsychiatric syndrome characterised by a spectrum of psychomotor *** editorial seeks to clarify the ambiguous aspects of catatonia,integrating recent research findings,including global studies and diagnostic *** discusses catatonia’s clinical manifestations,prevalence,and associated psychiatric and medical conditions,with particular emphasis on its frequent co-occurrence with schizophrenia and mood *** prevalence of catatonia,which varies across psychiatric populations,is illustrated by a significant study conducted in Nelson Mandela Bay,South *** study provides valuable insights into the effectiveness of the Bush-Francis Screening Instrument compared to the Diagnostic and Statistical Manual 5 criteria in diagnosing *** editorial evaluates treatment approaches,primarily focusing on benzodiazepines and electroconvulsive therapy,and discusses emerging therapeutic *** underscores the importance of robust diagnostic frameworks and early intervention in managing catatonia,as recommended by the latest evidence-based consensus ***,it suggests future research directions,particularly in exploring the neurobiological and genetic factors of catatonia,to enhance our understanding and improve treatment *** editorial succinctly aims to demystify catatonia and provide valuable insights for clinicians and researchers in mental health care.

关键词： Catatonia Schizophrenia Neuropsychiatry Benzodiazepines Electroconvulsive therapy Bush-Francis screening instrument Diagnosis

Highly Active Interfacial Sites in SFT-SnO_(2) Heterojunction Electrolyte for Enhanced Fuel Cell Performance via Engineered Energy Bands:Envisioned Theoretically and Experimentally

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Energy & Environmental Materials 2024年第3期7卷 384-397页

作者： Sajid Rauf Muhammad Bilal Hanif Faiz Wali Zuhra Tayyab Bin Zhu Naveed Mushtaq Yatao Yang Kashif Khan peter D.Lund Martin Motola Wei Xu College of Electronic and Information Engineering and State Key Laboratory of Radio frequency Heterogeneous Integration Shenzhen UniversityShenzhen 518000China Department of Inorganic Chemistry Faculty of Natural SciencesComenius University in BratislavaIlkovicova 684215BratislavaSlovakia College of Physics and Optoelectronic Engineering Shenzhen UniversityShenzhen 518060China School of Energy and Environment Southeast UniversityNo.2 Si Pai LouNanjing 210096China School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 611731China New Energy Technologies Group Department of Applied PhysicsAalto University School of ScienceP.O.Box 15100Fl-00076AaltoEspoo Finland

Extending the ionic conductivity is the pre-requisite of electrolytes in fuel cell technology for high-electrochemical *** this regard,the introduction of semiconductor-oxide materials and the approach of heterostructure formation by modulating energy bands to enhance ionic conduction acting as an electrolyte in fuel ***(n-type;SnO_(2))plays a key role by introducing into p-type SrFe_(0.2)Ti_(0.8)O_(3-δ)(SFT)semiconductor perovskite materials to construct p-n heterojunction for high ionic ***,two different composites of SFT and SnO_(2)are constructed by gluing p-and n-type SFT-SnO_(2),where the optimal composition of SFT-SnO_(2)(6∶4)heterostructure electrolyte-based fuel cell achieved excellent ionic conductivity 0.24 S cm^(-1)with power-output of 1004 mW cm^(-2)and high OCV 1.12 V at a low operational temperature of 500℃.The high power-output and significant ionic conductivity with durable operation of 54 h are accredited to SFT-SnO_(2)heterojunction formation including interfacial conduction assisted by a built-in electric field in fuel cell ***,the fuel conversion efficiency and considerable Faradaic efficiency reveal the compatibility of SFT-SnO_(2)heterostructure electrolyte and ruled-out short-circuiting ***,the first principle calculation provides sufficient information on structure optimization and energy-band structure modulation of SFT-SnO_(2).This strategy will provide new insight into semiconductor-based fuel cell technology to design novel electrolytes.

关键词： high ionic conductivity interfacial conduction modulated energy band structure p-n heterojunction semiconductors

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Health risk ranking of antibiotic resistance genes in the Yangtze River

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Environmental Science and Ecotechnology 2024年第5期21卷 113-122页

作者： Chunxia Jiang Zelong Zhao Hans-peter Grossart Feng Ju Yi Zhao Geoffrey Michael Gadd Ewa Korzeniewska Yuyi Yang Key Laboratory of Aquatic Botany and Watershed Ecology Wuhan Botanical GardenChinese Academy of SciencesWuhan430074China University of Chinese Academy of Sciences Beijing100049China Danjiangkou Wetland Ecosystem Field Scientific Observation and Research Station Chinese Academy of Sciences&Hubei ProvinceWuhan430074China Liaoning Key Laboratory of Marine Fishery Molecular Biology Liaoning Key Lab of Germplasm Improvement and Fine Seed Breeding of Marine Aquatic AnimalsLiaoning Ocean and Fisheries Science Research InstituteDalian116023China Leibniz-Institute for Freshwater Ecology and Inland Fisheries(IGB) Neuglobsow16775Germany Institute for Biochemistry and Biology Potsdam UniversityPotsdam14469Germany Key Laboratory of Coastal Environment and Resources of Zhejiang Province School of EngineeringWestlake UniversityHangzhou310030China School of Water Resources and Environment China University of Geosciences(Beijing)Beijing100083China Geomicrobiology Group School of Life SciencesUniversity of DundeeDundeeDD15EHScotlandUK State Key Laboratory of Heavy Oil Processing State Key Laboratory of Petroleum Pollution ControlChina University of PetroleumBeijing102249China Department of Water Protection Engineering and Environmental Microbiology Faculty of GeoengineeringUniversity of Warmia and Mazury in OlsztynOlsztyn10-720Poland

Antibiotic resistance is an escalating global health concern,exacerbated by the pervasive presence of antibiotic resistance genes(ARGs)in natural *** Yangtze River,the world's third-longest river,traversing areas with intense human activities,presents a unique ecosystem for studying the impact of these genes on human ***,we explored ARGs in the Yangtze River,examining 204 samples from six distinct habitats of approximately 6000 km of the river,including free-living and particle-associated settings,surface and bottom sediments,and surface and bottom bank *** shotgun sequencing,we generated an average of 13.69 Gb reads per *** findings revealed a significantly higher abundance and diversity of ARGs in water-borne bacteria compared to other habitats.A notable pattern of resistome coalescence was observed within similar habitat *** addition,we developed a framework for ranking the risk of ARG and a corresponding method for calculating the risk *** them,we identified water-borne bacteria as the highest contributors to health risks,and noted an increase in ARG risks in particle-associated bacteria correlating with heightened anthropogenic *** analysis using a weighted ARG risk index pinpointed the ChengdueChongqing and Yangtze River Delta urban agglomerations as regions of elevated health *** insights provide a critical new perspective on ARG health risk assessment,highlighting the urgent need for strategies to mitigate the impact of ARGs on human health and to preserve the ecological and economic sustainability of the Yangtze River for future human use.

关键词： Antibiotic resistance genes Yangtze River Habitat Coalescence Health risk

Electrogenic sulfur oxidation mediated by cable bacteria and its ecological effects

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Environmental Science and Ecotechnology 2024年第4期20卷 34-41页

作者： Zhenyu Wang Leonid Digel Yongqiang Yuan Hui Lu Yonggang Yang Carsten Vogt Hans-Hermann Richnow Lars peter Nielsen Department of Isotope Biogeochemistry Helmholtz Centre for Environmental Research e UFZPermoserstraße 1504318LeipzigGermany Center for Electromicrobiology Department of BiologyAarhus UniversityDK-8000AarhusDenmark Key Laboratory of Karst Georesources and Environment Ministry of EducationCollege of Resources and Environmental EngineeringGuizhou UniversityGuiyang550025China School of Environmental Science and Engineering Sun Yat-Sen UniversityGuangzhou510006China School of Life Science and Engineering Foshan UniversityFoshan528225China State Key Laboratory of Applied Microbiology Southern China Institute of MicrobiologyGuangdong Academy of SciencesGuangzhou510007China

At the sediment-water interfaces,filamentous cable bacteria transport electrons from sulfide oxidation along their filaments towards oxygen or nitrate as electron *** multicellular bacteria belonging to the family Desulfobulbaceae thus form a biogeobattery that mediates redox processes between multiple *** bacteria were first reported in *** the past years,cable bacteria have been found to be widely distributed across the *** potential in shaping the surface water environments has been extensively studied but is not fully *** this review,the biogeochemical characteristics,conduction mechanisms,and geographical distribution of cable bacteria,as well as their ecological effects,are systematically reviewed and *** insights for understanding and applying the role of cable bacteria in aquatic ecology are summarized.

关键词： Cable bacteria Electrogenic sulfur oxidation Long-distance electron transfer Aquatic ecology

Effect of age on the standardized ileal amino acid digestibility of soybean meal and canola meal in broilers

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Animal Nutrition 2024年第1期16卷 11-22页

作者： Mukti Barua M.Reza Abdollahi Faegheh Zaefarian Timothy J.Wester Channarayapatna K.Girish peter V.Chrystal Velmurugu Ravindran Monogastric Research Center School of Agriculture and Environment Massey University Department of Animal Science and Nutrition Faculty of Veterinary Medicine Chattogram Veterinary and Animal Sciences University Nutrition and Care Animal NutritionEvonik (SEA) Pte. Ltd Complete Feed Solutions

Standardized ileal digestibility coefficients (SIDC) of nitrogen (N) and amino acids (AA) in two protein sources (soybean meal [SBM] and canola meal [CM]) were investigated at six broiler ages (d 7, 14, 21, 28, 35, and 42). Two assay diets were formulated to contain either SBM (413 g/kg) or CM (553 g/kg) as the sole dietary AA source. Titanium dioxide (5 g/kg) was added as an indigestible marker. A total of 696 male broilers at 1 d old were allotted to 12 replicate cages per age group. Each assay diet was offered to birds for 4 d prior to the ileal digesta collection on d 7 (14 birds/cage), 14 (12 birds/cage), 21 (10 birds/cage), 28 (8 birds/cage), 35 (8 birds/cage) and 42 (6 birds/cage), respectively. The apparent digestibility coefficients were standardized using age-specific basal endogenous AA flows. In the SBM group, though the SIDC of N tended to be influenced (quadratic; P=0.075) by age, no linear or quadratic response of age effect was observed on the average SIDC of indispensable (IAA) and total AA (TAA). An age effect (quadratic; P<0.05) was observed on the average SIDC of dispensable AA (DAA) in SBM with the highest value recorded at d 7, followed by a decrease from d 14 to 28, which increased beyond d 35. The SIDC of some individual AA (Arg, Thr, Trp, Cys, Pro) were affected (P<0.05 or P<0.001) in a quadratic manner by age. In the CM, the SIDC of N, average SIDC of IAA, DAA and TAA were influenced (quadratic; P<0.05 or P<0.001) by age. The SIDC of N and average SIDC of DAA and TAA were higher from d 7 to 14, declined at d 21, and then increased beyond d 28. The average SIDC of IAA was low between d 7 and 28 and increased thereafter. The SIDC of individual AA were affected (linear or quadratic; P<0.05 or P<0.001) by different magnitudes by age. The age influence on the SIDC AA was variable, depending on the protein source and AA. The results demonstrate that age-specific SIDC AA data might need consideration in broiler feed formulations.

关键词： Age Amino acid Broiler Digestibility Protein source