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Journal of Central South University 2014年第11期21卷 4303-4310页

作者： choi seung-wook YOU Yen-Yoo NA Kwan-Sik Department of Knowledge Service & Consulting Hansung UniversitySeoul Korea Department of Management Information Systems Seowon UniversityCheongju Korea

In order to forecast promising technologies in the field of next generation mobile communication, various patent indicators were analyzed such as citation per patent, patent family information, patent share, increase rate, and patent activity. These indicators were quantified into several indexes and then integrated into an evaluation score to provide promising technologies. As a result of the suggested patent analysis, four technologies out of twenty two in details classification were selected, which showed outstanding technology competitiveness, high patent share and increasing rates as well as high recent-patent-ratios and triad-patent-family-ratios. Each of the selected technologies scored more than 10 points in total, and the following four technologies were suggested as promising ones in the field of next generation mobile communication: 1) 3GPP based mobile communication, 2) beyond 4G mobile communication, 3) IEEE 802.16 based mobile communication, which are in medium classification of broadband mobile communication system, and 4) testing/certification system of mobile communication, which is in medium classification of mobile communication testing/certification system.

关键词： next generation mobile communication promising technology forecasting patent information patent analysis patent indicators

Fabrication of SiC_p/AA5083 composite via friction stir welding

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中国有色金属学会会刊：英文版 2012年第S3期22卷 634-638页

作者： Byung-wook AHN Don-Hyun choi Yong-Hwan KIM seung-Boo JUNG School of Advanced Materials Science and Engineering Sungkyunkwan University

Microstructure and mechanical properties of SiCp /AA5083 composite fabricated by friction stir welding (FSW) were *** influence of the number of FSW passes on the distribution of SiC particles and mechanical properties in the joint was *** one pass,the SiC particles were entangled in the upper side of the stir zone (SZ).However,the particle distribution became more uniform after two passes due to the repeated stirring of the *** the SiC particles facilitate the grain refinement in the SZ by the pinning effect,the particle including region has much smaller grain size than the SZ without SiC *** SiCp /AA5083 composite region exhibits a Vickers hardness of HV90,which is much higher than the value of HV80 in the SZ produced by FSW without SiC particles.

关键词： metal matrix composite SiC particle friction stir welding mechanical property

Gene-diet interactions in gastric cancer risk: A systematic review

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World Journal of Gastroenterology 2014年第28期20卷 9600-9610页

作者： Jeongseon Kim Young Ae Cho wook Jin choi seung Hwa Jeong Molecular Epidemiology Branch Division of Cancer Epidemiology and PreventionResearch InstituteNational Cancer Center

AIM:To conduct a systematic review of the published epidemiological studies investigating the association of the interactions between gene variants and dietary intake with gastric cancer ***:A literature search was conducted in PubMed,EMBASE,and MEDLINE for articles published between January 2000 and July 2013,and 38 studies were *** studies included various dietary factors(e.g.,fruits and vegetables,soybean products,salt,meat,and alcohol)and genetic variants that are involved in various metabolic ***:Studies suggest that individuals who carry high-risk genetic variants and demonstrate particular dietary habits may have an increased risk of gastric cancer compared with those who do not carry high-risk genetic *** dietary patterns and variations in the frequency of genetic variants may explain the higher incidence of gastric cancer in a particular ***,most previous studies have limitations,such as a small sample size and a retrospective casecontrol *** addition,past studies have been unable to elucidate the specific mechanism in gene-diet interaction associated with gastric ***:Additional large prospective epidemiological and experimental studies are required to identify the gene-diet metabolic pathways related to gastric cancer susceptibility.

关键词： Gastric cancer Gene Diet Interaction

Hybrid Friction Stir Welding of High-carbon Steel

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Journal of Materials Science & Technology 2011年第2期27卷 127-130页

作者： Don-Hyun choi Chang-Yong Lee Byung-wook Ahn Jung-Hyun choi Yun-Mo Yeon Keun Song seung-Gab Hong Won-Bae Lee Ki-Bong Kang seung-Boo Jung School of Advanced Materials Science and Engineering Sungkyunkwan University 300 Cheoncheon-dongJangan-guSuwonGyeonggi-do 440-746South Korea Department of Mechanical Engineering Korea Advanced Institute of Science and Technology 335 GwahangnoYuseong-guDaejeon 305-701South Korea Department of Advanced Materials Application Suwon Science College 9-10Botong-liJeongnam-myeonHwasungGyeonggi-do 445-742South Korea Technical Research Lab POSCO Corp.Goedong-dongNam-guPohangGyeongbuk790-785South Korea

A high-carbon steel joint,SK5（0.84 wt% C）,was successfully welded by friction stir welding（FSW）,both without and with a gas torch,in order to control the cooling rate during *** welding,the weld zone comprised gray and black regions,corresponding to microstructural variation：a martensite structure and a duplex structure of ferrite and cementite,*** volume fraction of the martensite structure and the Vickers hardness in the welds were decreased with the using of the gas torch,which was related with the lower cooling rate.

关键词： Friction stir welding High-carbon steel Transformation Martensite

Ex situ aging effect on sulfonated poly(ether ether ketone) membrane:Hydration-dehydration cycling and hydrothermal treatment

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Journal of Energy Chemistry 2022年第7期31卷 583-592,I0014页

作者： seung-Young choi Kyeong Sik Jin Polymer&Materials Chemistry Department of ChemistryLund UniversitySE-22100Sweden Center for Hydrogen·Fuel Cell Research Korea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea Pohang Accelerator Laboratory Pohang University of Science and Technology(POSTECH)PohangKyungbuk 37673Republic of Korea

Prolonged hydrothermal treatment for sulfonated poly(ether ether ketone) membranes induces mechanical degradation and developing hydrophilic-hydrophobic phase separation, simultaneously. The enhanced phase separation provides incremental proton conductivity to the membranes, whereas mechanical degradation drastically reduces device stability. On this basis, we describe here the effects of two different ex situ aging processes on sulfonated poly(ether ether ketone) membranes: hydrationdehydration cycling and prolonged hydrothermal treatment. Both aged membranes exhibited enhanced phase separation under the hydrated conditions, as characterized by small angle X-ray ***, when the aged membranes were dried again, the nanostructure of the membranes aged via the hydration-dehydration cycling was recoverable, whereas that of the membranes aged via prolonged hydrothermal treatment was irreversible. Furthermore, the two differently aged membranes showed clear differences in thermal, mechanical, and electrochemical properties. Finally, we implemented both aged membranes in fuel cell application. The sample aged via hydration-dehydration cycling maintained its improved cell performance, whereas the sample aged via hydrothermal treatment showed drastically reduced cell performance after durability test for 50 h.

关键词： Sulfonated poly(ether ether ketone) Humidity cycle test Ex situ aging Proton exchange membrane Fuel cell

Light-stabilized FHA2 suppresses miRNA biogenesis through interactions with DCL1 and HYL1

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Molecular Plant 2021年第4期14卷 647-663页

作者： seung Jun Park Suk Won choi Gu Min Kim Christian Moller Hyun-Sook Pai Seong wook Yang Department of Systems Biology College of Life Science and BiotechnologyYonsei UniversitySeoul 120749Korea EDepartment of Systems Biology Institute of Life Science and BiotechnologyYonsei UniversitySeoul 120-749Korea Department of Plant and Environnental Sciences Faculty of ScienceUniversity of CopenhagenThorvaldsensvei 40DK-1871 FrederiksbergCopenhagenDenmark Pohang University of Science and Technology(POSTECH) 77 Cheongam-RoNam-GuPohangGyeongbuk37673.Korea These authors contributed equally to this article.

The precise regulation of microRNA(miRNA)biogenesis is crucial for plant development,which requires core microprocessors and many fine tuners to coordinate their miRNA processing activity/specificity in fluctuating cellular *** de-etiolation,light triggers a dramatic accumulation of core microprocessors and primary miRNAs(pri-miRNAs)but decreases pri-miRNA processing activity,resulting in relatively constant miRNA *** mechanisms underlying these seemingly contradictory regulatory changes remain *** this study,we identified forkhead-associated domain 2(FHA2)as a light-stabilized suppressor of miRNA *** found that FHA2 deficiency increased the level of mature miRNAs,accompanied by a reduction in pri-miRNAs and target *** assays showed that FHA2 associates with the core microprocessors DCL1,HYL1,and SE,forming a complex to suppress their pri-miRNA processing *** analyses revealed that FHA2 promotes HYL1 binding but inhibits the binding of DCL1-PAZ-RNase-RNA-binding domains(DCL1-PRR)to miRNAs,whereas FHA2 does not directly bind to these ***,we found that FHA2 protein is unstable in the dark but stabilized by light during ***,disruption of FH A led to defects in light-triggered changes in miRNA expression and reduced the survival rate of deetiolated seedlings after prolonged light ***,these data suggest that FHA2 is a novel light-stabilized suppressor of miRNA biogenesis and plays a role in fine-tuning miRNA processing during de-etiolation.

关键词： miRNA biogenesis Suppressor of the microprocessor miRNA-biogenetic inconsistency

A digital application for implementing the ICD-11 traditional medicine chapter

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Journal of Integrative Medicine 2020年第6期18卷 455-458页

作者： seung-hoon choi Department of Life Convergence Graduate SchoolDankook UniversityYonginGyeonggi-do 16890Republic of Korea

On May 25,2019,the World Health Assembly approved the eleventh revision of the International Statistical Classification of Diseases and Related Health Problems(ICD-11),containing a chapter on traditional *** means that the traditional East Asian medicine(TEAM)is now officially recognized as a part of mainstream medical ***,the patterns presented in the ICD-11 traditional medicine chapter are only the tip of the iceberg of TEAM clinical practice,and it will be necessary to supplement and upgrade the *** order to implement this,objectification and standardization of TEAM must be premised,and grafting with proper modern science and technology is *** Identification and Prescription Expert-11(PIPE-11),which is a TEAM clinical decision support system,adopts vastly from clinical literature on pattern identification and the *** adopting the rule-based reasoning method,the way of diagnosis and prescription by a TEAM practitioner in actual clinical practice is implemented as it ***-11 could support to improve both the accuracy of medical diagnosis and the reliability of the medical treatment of TEAM in clinical *** the field of research,it might facilitate the usage for reliable reference for symptoms and signs retrieval and patient *** the field of education,it can provide a high level of training for learning pattern identification and prescription,and further be used to reinforce skills of diagnosis and prescription by providing self-simulation ***,PIPE-11 as a digital application is expected to support the traditional medicine chapter of ICD-11 to successfully contribute to the improvement of human health.

关键词： ICD-11 PIPE-11 Traditional medicine Clinical decision support system Formula Pattern

Ethyl acetate fraction of Sargassum pallidum extract attenuates particulate matter-induced oxidative stress and inflammation in keratinocytes and zebrafish

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Asian Pacific Journal of Tropical Biomedicine 2024年第4期14卷 137-146页

作者： wook Chul Kim Ji-Won Park Bohyun Yun WonWoo Lee Kyung-Min choi seung-Hong Lee Department of Medical Science Soonchunhyang UniversityAsan 31538Republic of Korea Honam National Institute of Biological Resources 99Gohadoan-gilMokpo-siJeollanam-do 58762Republic of Korea Department of Pharmaceutical Engineering Soonchunhyang UniversityAsan 31538Republic of Korea

Objective:To evaluate the effect of the ethyl acetate fraction derived from Sargassum pallidum extract against particulate matter(PM)-induced oxidative stress and inflammation in HaCaT cells and ***:HaCaT cells and zebrafish were used to evaluate the protective effects of the ethyl acetate fraction of Sargassum pallidum extract against PM-induced oxidative stress and *** production of nitric oxide(NO),intracellular ROS,prostaglandin E_(2)(PGE_(2)),and pro-inflammatory cytokines,and the expression levels of COX-2,iNOS,and NF-κB were evaluated in PM-induced HaCaT ***,the levels of ROS,NO,and lipid peroxidation were assessed in the PM-exposed zebrafish ***:The ethyl acetate fraction of Sargassum pallidum extract significantly decreased the production of NO,intracellular ROS,and PGE_(2) in PM-induced HaCaT *** addition,the fraction markedly suppressed the levels of pro-inflammatory cytokines and inhibited the expression levels of COX-2,iNOS,and NF-κ***,it displayed remarkable protective effects against PM-induced inflammatory response and oxidative stress,represented by the reduction of NO,ROS,and lipid peroxidation in ***:The ethyl acetate fraction of Sargassum pallidum extract exhibits a protective effect against PM-induced oxidative stress and inflammation both in vitro and in vivo and has the potential as a candidate for the development of pharmaceutical and cosmeceutical products.

关键词： Particulate matter Inflammation Oxidative stress Sargassum pallidum Ethyl acetate fraction Zebrafish

Ventricular fibrillation and sudden cardiac arrest in apical hypertrophic cardiomyopathy:Two case reports

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World Journal of Clinical Cases 2021年第35期9卷 11102-11107页

作者： Yae Min Park Albert Youngwoo Jang wook-Jin Chung seung Hwan Han Christopher Semsarian In Suck choi Department ofCardiology Gachon University Gil Medical CenterIncheon 21556South Korea Agnes Ginges Centre for Molecular Cardiology Centenary Institute The University of SydneySydney 21556Australia

BACKGROUND Apical hypertrophic cardiomyopathy(HCM)is considered to have a benign prognosis in terms of cardiovascular *** serial case report aimed to raise awareness of ventricular fibrillation(VF)and sudden cardiac death(SCD)in apical *** SUMMARY Here we describe two rare cases of apical HCM that presented with documented VF and sudden cardiac *** patients were previously not recommended for primary prevention using implantable cardioverter-defibrillator(ICD)therapy based on current ***,both received ICD therapy for the secondary prevention of *** These cases illustrate serious complications including VF and aborted sudden cardiac arrest in apical HCM patients who are initially not candidates for primary prevention using ICD implantation based on current guidelines.

关键词： Apical hypertrophic cardiomyopathy Ventricular fibrillation Implantable cardioverter-defibrillator Case report

Short-circuit Current Characteristics of Wind Generators

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电力系统自动化 2012年第8期36卷 110-114页

作者： seung-Jae LEE Myeon-Song choi Department of Electrical Engineering Myongji University

To study the effects of wind generators on distribution system protection,the short-circuit current(SCC) characteristics of wind generators is *** there are many researches on the issue,a clear agreement has not been reached so *** SCC characteristics for different wind generators are *** simulation is performed in the same system integrated with different kinds of wind generators,and their results are compared with those reported in IEEE *** detection possibility by overcurrent relay(OCR)is discussed based on the simulation results.

关键词：风力发电机组短路电流电流特性配电系统 PSCAD 过流继电器 IEEE 通过检测