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香港三号干线工程

土木工程学报 2001年第1期34卷 92-99页

作者：刘正光香港特别行政区政府路政署

三号干线为香港特别行政区最重要干线之一，全长２９ｋｍ，是一条贯通香港西部地区的南北走廊。其连接香港市区，经九龙半岛而通往新界西北部与深圳特区之交接点地落马洲，再接通皇岗，进入中国经济最活跃的地带──深圳特区，进而连接... 详细信息

三号干线为香港特别行政区最重要干线之一，全长２９ｋｍ，是一条贯通香港西部地区的南北走廊。其连接香港市区，经九龙半岛而通往新界西北部与深圳特区之交接点地落马洲，再接通皇岗，进入中国经济最活跃的地带──深圳特区，进而连接至广州的高速公路。三号干线并西接青屿干线（由青马大桥与汲水门桥构成）直抵世界最繁忙的航空港──香港国际机场。由此看来，三号干线不但对香港整体经济利益有很大贡献，而且可以促进内地与香港的交通往来，为祖国内地经香港通向世界的窗口。

关键词：沉管隧道钻挖隧道斜拉桥高速公路

Attitudes of visitors at adult intensive care unit toward organ donation and organ support

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Chinese Medical Journal 2019年第3期132卷 373-376页

作者： Nga-Wing Tsai Yee-Man Leung Pauline Yeung Ng Ting Liong Sui-Fong Lee Chun-wai Ngai wai-ching Sin Jenny Koo wai-Ming Chan Adult Intensive Care Unit Queen Mary HospitalHong Kong 999077China Intensive Care Unit United Christian HospitalHong Kong 999077China Intensive Care Unit Kwong Wah HospitalHong Kong 999077China Central Nursing Department Queen Mary HospitalHong Kong 999077China

The concept of brain death was 1st introduced in the 1960s, providing an essential conceptual change to medical practice,[1] and its diagnosis is based on demonstrating the complete, irreversible cessation of brainste... 详细信息

关键词： brain death toward organ donation organ support

Delineation of Biological Tumor Volume from Positron Emission Tomography Images in Nasopharyngeal Carcinoma

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Journal of Biomedical Science and Engineering 2014年第11期7卷 857-865页

作者： Ka-wai Wong Dora Lai-Wan kwong Pek-Lan Khong Victor Ho-Fun Lee Sherry Chor-Yi Ng Martin wai-Ming Law The Department of Clinical Oncology Queen Elizabeth Hospital Hong Kong China The Department of Clinical Oncology Queen Mary Hospital Hong Kong China The Department of Clinical Oncology The University of Hong Kong Hong Kong China The Department of Diagnostic Radiology Queen Mary Hospital Hong Kong China The Department of Diagnostic Radiology The University of Hong Kong Hong Kong China

Objective: To develop an auto-segmentation method for delineating the biological tumor volume of nasopharyngeal carcinoma from positron emission tomography images. Methods: A phantom consisting of a water tank with fixed background fluorodeoxyglucose [18F-FDG] activity and spheres with diameters ranging from 2.1 to 5 cm with varying activities of FDG were used to simulate tumors of different sizes and FDG uptake. The phantom was scanned with a PET/CT scan at different sphere to background intensity ratios. An optimum fixed percentage threshold (FT) approach and a signal-to-background ratio (SBR) approach were developed to estimate the true size of the spheres from the PET images. Both approaches were further evaluated in patient images for validation. Twenty-two patients with NPC from stage T1 to T4 were included. The PET based biological tumor volumes (BTV) were delineated with both FT (BTVFT) and SBR (BTVSBR) approaches and compared with the gross tumor volume localized from MRI (GTVMR). The mean volumes of BTVFT and BTVSBR were compared and the degree of overlap between GTVMR and both BTVs was evaluated. Paired t-tests were used for statistical analysis. Results: The optimal FT value was 36.5% of maximal intensity, and SBR approach was represented by an inverse linear regression model. The estimated volume of spheres segmented by both approaches shows no significant difference from the true volume of spheres (p > 0.05), but the average absolute errors were smaller from SBR approach than FT approach (p = 0.008). GTVMR was larger than both BTVFT (p = 0.003) and BTVSBR (p SBR with GTVMR is significantly larger than with BTVFT (0.52 and 0.42 respectively, p MR for radiotherapy planning purpose.

关键词： Segmentation Approach SBR Fixed Threshold NPC PET

Early-onset primary torsional dystonia in a 4-generation Chinese family with a mutation in the DYT1 gene

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Chinese Medical Journal 2005年第10期118卷 873-876页

作者： YEUNG wai Lan LAM ching Wan CHENG wai Tsoi SIN Ngai Chuen WONG Wing Kin WONG Chun Nei TSE Ka Ming FOK Tai Fai Departments of Paediatrics Prince of Wales HospitalThe Chinese University of Hong KongHong KongChina Chemical Patholog Prince of Wales HospitalThe Chinese University of Hong KongHong KongChina Department of Paediatrics and Adolescent Medicine Queen Mary HospitalUniversity of Hong Kong Nuclear Medicine&PET Division Scanning DepartmentSt.Teresa’s HospitalHong KongChina

Primary torsion dystonia(PTD)is a clinically and genetically heterogeneous movement *** least thirteen different types of dystonia can be distinguished on a genetic basis.~1 The DYT1 gene was first mapped by Ozelius et al in 1989.~2(Kramer et)al^3 linked the same locus to PTD in 12 Ashkenazi Jewish families in *** patients with early-onset generalized PTD were caused by the same three base pair(GAG)deletion in the DYT1 gene on chromosome 9q34.^(1,4,5)The product of the gene is a protein called torsinA.~5(Although the)function of this protein is as yet uncertain,it is widely distributed throughout the brain with high levels in the substantia nigra compacta dopamine neurones.

关键词： DYT1 gene dystonia positron emission tomography

NTO THE DARK ABYSS EXPLORING SOUTH CHINA’S EXPANSIVE UNDERGROUND RIVER SYSTEM

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城市漫步（上海版、英文） 2020年第1期 38-47页

作者： Matthew Bossons via Rachel Berkley(images) Cara Chu wai-ching Vincent Lou 不详

On June 23,2018,12 young Thai boys and their assistant football coach wandered into a karst cave in northern Thailand,near the border with *** happened next would captivate the world and lead to a complex and daring international rescue operation:The 10.3-kilometer-long Tham Luang cave flooded,trapping the boys in total blackness nearly 2.5 kilometers from the cave entrance.

关键词： karst happen black

Characterization of 3D Printed Poly(3-Hydroxybutyric-Co-3-Hydroxyvalerate) by Fused Granular Fabrication through Thermal and Mechanical Analyses

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Journal of Materials Science and Chemical Engineering 2023年第12期11卷 54-63页

作者： Lok-ching Wu Cheng-Hao Lee Yanming Wang Yaohui Liu Chi-wai Kan School of Fashion and Textiles Hong Kong Polytechnic University Hong Kong China Faculty of Science and Technology Technological and Higher Education Institute of Hong Kong Hong Kong China

Poly[R-3-hydroxybutyrate-co-(R-3-hydroxyvalerate)] (PHBVs) copolymers are promising biopolymers, which could substitute petroleum-based plastics for various applications. PHB and PHBV pellets were processed on a customized 3D printer via Fused Granular Manufacturing (FGM) approach modified with a Mahor screw extruder. To anticipate the behaviour of PHBVs when transformed using conventional thermo-mechanical shaping processes, thermal and mechanical analyses were carried out in order to better understand the effect of annealing temperature on their crystallization behaviour and mechanical properties of PHB polymer and PHBV copolymer. The objectives of the present work were to propose an experimental strategy to study the melting and crystallization events, crystalline structure changes, and mechanical performances of both PHB homopolymer and PHBV copolymer according to identical thermal annealing treatments. A monitoring of 3D printed PHB and PHBV structures was achieved by coupling Differential Scanning Calorimetry (DSC) and tensile tests. .

关键词： Additive Manufacturing 3D Printing Biodegradable Plastic Fused Gran-ular Manufacturing Poly[R-3-Hydroxybutyrate-Co-(R-3-Hydroxyvalerate)]

A cross-sectional study on compliance with topical glaucoma medication and its associated socioeconomic burden for a Chinese population

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International Journal of Ophthalmology(English edition) 2017年第2期10卷 293-299页

作者： Man-Hin Lui Jason Chun Ho Lam Yi Lee kwong Tak Siu Wong Pak Long Cheung Sherri Shun Yan Lai Pak Lun Yuen wai Yiu Lam Ho Yan Chan Yiu Fai Wong Jimmy Shiu Ming Lai Kendrick Co Shih Li Ka Shing Faculty of Medicine the University of Hong KongPokfulamHong KongChina Department of Ophthalmology Li Ka Shing Faculty of Medicinethe University of Hong KongPokfulamHongKongChina Department of Ophthalmology Queen Mary HospitalPokfulamHong KongChina

AIM： To estimate the overall drug compliance for local Chinese glaucoma patients on long-term topical ***： This was a retrospective cross-sectional ***-seven primary glaucoma patients from the subspecialty clinic of a publicly-funded tertiary care hospital in Hong Kong completed a questionnaire on compliance with topical glaucoma medication,attitude towards glaucoma and therapy and vision related quality of *** was defined as reporting missing more than or equal to 10% of the prescribed topical glaucoma medication during the 2wk immediately prior to the *** between noncompliance and demographics,attitude,disease and treatment status was *** was estimated with quality of life and direct medical cost involved with *** logistic regression on noncompliance was performed on selected ***： Compliance was calculated as 75%（95% CI： 64%-87%） among 57 subjects（mean age 69 y,female 51%）.No statistical significant relationship was established between noncompliance and any single factors or ***（P=0.048） and forgetfulness（P=0.064） were found to be marginally significant predictive factors on noncompliance in multivariable logistic *** might be related（P=0.130） to poorer self-rated vision-associated quality of *** societal cost of noncompliance was estimated to be over 2510 life-years and US$ 3.7 million ***： The compliance of Chinese glaucoma patients in Hong Kong is comparable to other parts in the world,and carries detrimental impacts on individual and societal *** and forgetfulness are two possible independent predictors for noncompliance.

关键词： glaucoma eye drop compliance quality of life

Initial Experience on Robot-assisted Radical Prostatectomy

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Initial Experience on Robot-assisted Radical Prostatectomy

玻璃体腔注射Bevacizumab联合Ahmed青光眼阀植入治疗新生血管性青光眼

第十七届全国泌尿外科学术会议

作者： To Kim Chung Ma wai Kit Chu Tin Yu Liu Pak Ling Chan wai Hee Yiu Ming kwong Division of Urology Department of SurgeryPrincess Margaret Hospital

Purpose To report our initial experience on robot-assisted radical prostatectomy. Materials and methods Da Vinci S Surgical System was installed in our center in June 2009.46 consecutive patients with prostate cancer who

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中国实用眼科杂志 2011年第8期29卷 779-784页

作者：张海涛王保君胡俊喜徐英英 wai-ching Lam 新乡医学院第一附属医院眼科河南省新乡市453100 加拿大多伦多大学西部医院眼科

目的观察玻璃体腔注射Bevacizumab联合Ahmed青光眼阀植入治疗新生血管性青光眼（NVG）的术后疗效和并发症。方法回顾性临床病例对照研究。选择新乡医学院第一附属医院眼科在2007年至2008年2月间接受过玻璃体腔注射Bevacizumab0．05mL／1... 详细信息

目的观察玻璃体腔注射Bevacizumab联合Ahmed青光眼阀植入治疗新生血管性青光眼（NVG）的术后疗效和并发症。方法回顾性临床病例对照研究。选择新乡医学院第一附属医院眼科在2007年至2008年2月间接受过玻璃体腔注射Bevacizumab0．05mL／1．25mg和Ahmed青光眼阀植入术的NVG患者，术前及术后定期随访检查，记录抗青光眼药物数量、Snellen视力、Godmann压平式眼压计测量的IOP等项目。手术成功标准：术后IOP处于6～21mmHg范围内，不再使用或不需额外增加抗青光眼药物治疗，不需进一步抗青光眼手术治疗，术眼视力未丧失光感。结果纳入分析35例（35只眼），随访时间（24．6±14.2）月。Ahmed青光眼阀植入术后IOP比术前降低（P〈0．01），其中术前、术后6月、1年和3年分别为（44．9±4．8）mmHg、（1822±4．0）mmHg、（15．5±3．3）mmHg和（9．8±2．6）mmHg（1mmHg=0．133kPa）；抗青光眼药物数量术后较术前减少（P〈0．01），其中术前、术后6月、1年和3年分别为（3．3±0．5）种、（0．9±0．5）种、（0．8±0．9）种和（0．8±0．6）种。最后一次随访时，视力较术前保持稳定19例（54．3％），改善4例（11．4％），下降12例（34．3％），丧失光感3例（8．6％）。经3年随访，失败病例7例（20．0％o经Kaplan—Meier生存分析，术后1年、2年、3年累计生存率分别为82．9％、74．1％和71．0％。经Cox逐步回归分析，术前视力较差（〈20／400）与术后生存时间具有相关性（RR=3．571，P〈0．05）。术后并发症8例（22．9％），其中前房出血2例（5．7％），脉络膜渗液2例（5．7％），其余并发症较少见，未发生需要取出引流阀的并发症。结论玻璃体腔注射Bevacizumab联合Ahmed青光眼阀植入术安全有效，可作为新生血管性青光眼临床治疗方法之一。

关键词： Ahmed青光眼阀新生血管性青光眼 Bevacizumab 玻璃体注射