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MIS 5e sea surface temperature estimation;a multi-proxy approach using a marine macrofossil assemblage(Mar Piccolo,Gulf of Taranto,Southern Italy)

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Journal of Palaeogeography 2024年第2期13卷 327-350页

作者： Pierluigi Santagati Edoardo perri Maria Pia Bernasconi Mario Borrelli Salvatore Guerrieri Salvatore Critelli Dipartimento di Biologia Ecologia e Scienze della TerraUniversita della Calabriavia Pietro Bucci87036 Arcavacata di RendeCosenzaItaly Dipartimento di Ingegneria Ambientale Universita della Calabriavia Pietro Bucci87036 Arcavacata di RendeCosenzaItaly

It is reported a multi-proxy palaeoclimatic study conducted on a MIS 5e calcarenite from the Mar Piccolo Basin(MP),Gulf of Taranto(GT)(Central Mediterranean).The calcarenite returned a rich malacofauna consisting of 120 extant species,including four of the tropical Senegalese Fauna,today absent in the *** biogeographic-climatic affinity of the assemblage shows,compared to today,a double percentage of warm affinity species,while the cold affinity species are nearly equally represented,indicating a warmer but not strictly tropical *** is confirmed by the most recurring preferred SST ranges of the assemblage,indicating an average of 20℃.The skeletal compositions of five well-preserved molluscan and coral specimens were analyzed for trace elements and stable isotopes for further mean SST *** the comparison of the results of several equations available in literature,it appears that only some SST estimations are realistic,converging into similar values of,on average,20.8±0.9℃.Considering all the used proxies,the MIS 5e SST difference compared to today falls in the range 1.2—2.0℃for the GT(being a more reasonable scenario)and 2.0—2.8℃for the *** is not a firmly tropical-like SST setting as suggested by the sole Senegalese fauna,indicating at least 2.7℃—3.5℃more than today’s GT and MP,*** approximations and assumptions made for obtaining SST values with any single proxy indicate the need of a multi-proxy approach to define the best SST estimation.

关键词： MiS 5e Sea surface temperature Palaeoclimate proxy Fossil fauna Gulf of Taranto

Endoscopic ultrasound and magnetic resonance imaging for re-staging rectal cancer after radiotherapy

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World Journal of Gastroenterology 2009年第44期15卷 5563-5567页

作者： Gianni Mezzi Paolo Giorgio Arcidiacono Silvia Carrara Francesco perri Maria chiara Petrone Francesco De Cobelli Simone Gusmini Carlo Staudacher Alessandro Del Maschio Pier Alberto Testoni Gastroenterology and Gastrointestinal Endoscopy Unit IRCCS Vita-Salute UniversitySan Raffaele Scientific Institute20132 MilanItaly Gastroenterology Unit San Benedetto del Tronto Hospital63039 San Benedetto del Tronto (AP)Italy Alessandro Del Maschio Department of RadiologyIRCCS Vita-Salute UniversitySan Raffaele Scientific Institute20132 MilanItaly Department of Surgery IRCCS Vita-Salute UniversitySan Raffaele Scientific Institute20132 MilanItaly

AIM:To compare the sensitivity and specificity of two imaging techniques,endoscopic ultrasound (EUS) and magnetic resonance imaging (MRI),in patients with rectal cancer after neoadjuvant chemoradiation therapy. And we compared EUS and MRI data with histological fi ndings from surgical specimens. METHODS:Thirty-nine consecutive patients (51.3% Male; mean age:68.2 ± 8.9 years) with histologically confirmed distal rectal cancer were examined for staging. All patients underwent EUS and MRI imaging before and after neoadjuvant chemoradiation therapy. RESULTS:After neoadjuvant chemoradiation,EUS and MRI correctly classified 46% (18/39) and 44% (17/39) of patients,respectively,in line with their histological T stage (P > 0.05). These proportions were higher for both techniques when nodal involvement was considered:69% (27/39) and 62% (24/39). When patients were sorted into T and N subgroups,the diagnostic accuracy of EUS was better than MRI for patients withT0-T2 (44% vs 33%,P > 0.05) and N0 disease (87% vs 52%,P = 0.013). However,MRI was more accurate than EUS in T and N staging for patients with more advanced disease after radiotherapy,though these differences did not reach statistical significance. CONCLUSION:EUS and MRI are accurate imaging techniques for staging rectal cancer. However,after neoadjuvant RT-CT,the role of both methods in the assessment of residual rectal tumors remains uncertain.

关键词：磁共振成像直肠癌内镜超声放疗成像技术 MRI 平均年龄

Distribution of Respiratory Tract Infectious Diseases in Relation to Particulate Matter(PM_(2.5))Concentration in Selected Urban Centres in Niger Delta Region of Nigeria

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Journal of Geographical Research 2022年第1期5卷 1-11页

作者： Tamuno-owunari perri Vincent Ezikornwor Weli Bright Poronakie Tombari Bodo Department of Geography and Environmental Studies Ignatius Ajuru University of EducationRumuluminiRivers stateNigeria Department of Geography and Environmental Management University of Port HarcourtNigeria Department of Flood Erosion Control and Coastal Zone ManagementRivers State Ministry of EnvironmentRivers StateNigeria

Due to the visibility of soot in the environment of the Niger Delta especially Rivers State that has led to the increase of Respiratory Tract Infections(RTIs)in the region,this study was undertaken to determine the relationship between Particulate Matter(PM_(2.5))concentration and the incident of Respiratory Tract Infections(RTIs)in selected urban centres of the Niger *** on RTIs were collected from the Hospital Management Boards of the Ministries of Health of Rivers,Bayelsa and Delta States and the data for PM_(2.5)were remotely sensed from 2016 to 2019,and subsequently analyzed with ANOVA and Spearman’s rank correlation *** findings of this study revealed that there was significant variation in the occurrence of PM_(2.5)across the selected urban centres in the Niger Delta *** PM_(2.5)for the reviewed years was far above the World Health Organization(WHO)annual permissible limit of 10μg/m^(3)thereby exacerbating Respiratory Tract Infections(RTIs).The epidemiology of the RTIs showed that there are basically four(4)prominent RTI diseases:Asthma,Tuberculosis,Pneumonia and Chronic Obstructive Pulmonary Disease(COPD).The result of this study showed that the concentration of PM_(2.5)varies in all the selected cities,and the mean monthly variation(2016-2019)showed that Port Harcourt had 47.27μg/m^(3)for January while Yenagoa and Asaba had 46μg/m^(3)and 47.51μg/m^(3)respectively for January;while the lowest mean value in the cities were seen within the month of September and October,which also had a strong seasonal influence on the concentration of PM_(2.5).The concentration of PM_(2.5)and the numbers of RTIs also gradually increases in the study areas from 2016 to *** study recommends that the necessary regulatory bodies should closely monitor the activities of the companies likely to cause such pollution;guild them through their operations and give prompt sanctions and heavy fines to defaulters of the accepted standards.

关键词： Soot Particulate matter and respiratory tract infections Diseases

Chemical and minero-petrographical changes on granulite rocks affected by weathering processes

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Frontiers of Earth Science 2019年第2期13卷 247-261页

作者： Carmine APOLLARO Francesco perri Emilia LE PERA Ilaria FUOCO Teresa CRITELLI DiBEST University of Calabria1-87036 Arcavacata di Rende (CS)Italy

The purpose of this work is to study the weathering processes of the granulite rocks of the Serre Massif (southern Calabria,Italy) using a multidisciplinary approach based on field studies,geochemical modeling,and minero?petrographical *** granulite rocks are plagioclase-rich with minor amphibole,clinopyroxene,orthopyroxene,biotite,and garnet and their texture are *** reaction path modeling was performed to simulate the evolution of groundwaters upon interaction with local granulite by means of the software package EQ3/6,version *** were performed in kinetic (time) mode under a closed system at a constant temperature of 11.5℃,(which reproduces the average temperature of local area) and fixing the fugacity of CO2 at 10-2.34 bar (mean value).During the most advanced stage of weathering the main mineralogical changes are: partial destruction and transformation of biotite and plagioclase associated with neoformation of ferruginous products and secondary clay minerals producing a change in the origin rock *** secondary solid phases observed during the geochemical modeling (kaolinite,vermiculite and ferrihydrite) are similar to those found in this natural ***,the soil-like material mainly characterized by mostly sand to gravel grain-size fractions is the final result of the weathering processes.

关键词： Serre Massif granulitic rocks mineralogy petrography weathering profile reaction path-modeling

胰头肿瘤病人胰腺切缘的定量边缘分析:胰腺切缘与术后胰瘘发生的相关性

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国际医学放射学杂志 2024年第3期 374-374页

作者： M.C.Ambrosetti A.Ambrosetti G.perri C.Gasparini G.Marchegiani R.Salvia 吴玉平

摘要目的评估胰十二指肠切除术（PD）病人胰腺定量边缘分析代替实质硬度，与术后胰瘘（POPF）发生率之间的相关性。方法连续纳入2018年3月—2019年11月期间在

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Mitochondrial dysfunction in Parkinson＇s disease： a possible target for neuroprotection

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Frontiers in Biology 2014年第6期9卷 489-503页

作者： Jacqueline A. GLEAVE Peter D. perri Joanne E. NASH Centre for Neurobiology of Stress Department of Biological Sciences University of Toronto Scarborough Toronto Ontario M1C1A4Canada

Mitochondria are dynamic organelles which are required for maintaining cellular homeostasis. Thus, it is not surprising that irregularities in mitochondrial function result in cellular damage and are linked with neurodegenerative diseases, such as Parkinson＇s disease. Evidence that mitochondrial dysfunction is key to the pathogenesis of Parkinson＇s disease is founded in studies in post-mortem tissue from patients with Parkinson＇s disease, and also from genetic studies stemming from patients with familial Parkinson＇s disease. Whether triggered by environmental or genetic factors, mitochondrial dysfunction occurs early in the pathogenic process, and is central to Parkinson＇s disease pathology. As such, targeting the mitochondria to slow or halt disease progression is an attractive strategy for disease-modifying agents in Parkinson＇s disease. Indeed, several therapies which target the mitochondria have been investigated as neuroproteetive treatments for Parkinson＇s disease. This review will discuss the evidence supporting mitochondrial dysfunction in Parkinson＇s disease pathology as well as treatment strategies that target the mitochondria.

关键词： Parkinson's disease mitochondria oxidative stress lysosome UPS

Oleuropein-Specific-β-Glucosidase Activity Marks the Early Response of Olive Fruits (Olea europaea) to Mimed Insect Attack

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Agricultural Sciences in China 2008年第6期7卷 703-712页

作者： Antonia Spadafora Silvia Mazzuca Francesca Fiorella Chiappetta Attilio Parise Enzo perri Anna Maria Innocenti Laboratorio di Citofisiologia Vegetale Dipartimento di Ecologia Cubo 6b Ponte Bucci Università della Calabria 87030 Rende (CS) Italy C.R.A. Centro di Ricerca per l'Olivicoltura e l'Industria Olearia Contrada Li Rocchi 87030 Rende Italy

Olive fruits are seriously deteriorated by pre and postharvest damage due to the attack of insects, such as Bactrocera olaea, which strongly alters the quality of olives. Defence response in olive fruits injured both by pathogens and by mechanical damages has been associated with the enzyme β-glucosidase, which specifically hydrolyses oleuropein, producing highly reactive aldehyde molecules. In situ detection of ^-glucosidase activity in olive fruit tissues following injury, which simulates Bactrocera oleae punctures, is reported. The assay was performed in two cultivars showing different degrees of susceptibilities to fly infestation. In both cultivars, the histochemical assay for β-glucosidase showed that within 20 min after the injury, a strong ^-glucosidase activity could be observed in the damaged tissues. Thereafter a progressive enzyme inactivation occurred starting from tissues around the boundary of the injury with decrease of the enzyme activity and stopped after 3 h. Whereas the mass of active cells reached a distance of （300±50） μm from the edge of the injury. Biochemical analyses showed that in extracts of the injured fruit, β-glucosidase activity rapidly increased within 20 min from injury, thereafter decreasing and reaching values comparable with those in intact fruits. Following puncture, the oleuropein contents did not change significantly in the high susceptibility cultivar, whereas it rapidly decreased in the cultivar showing low susceptibility. The results strongly suggest that olive fruits susceptible towards fly infestation could be related to the ability of the oleuropein-degrading-β-glucosidase to produce the highly reactive molecules in the damaged tissues. As a consequence of puncture, high level of peroxidase activity was detected. This feature also suggested that this enzyme could play a key role in the defence response against insect injuries.

关键词： β-glucosidase (EC 3.2.1.21) oleuropein Olea europaea Bactrocera oleae infestation cultivar resistance

If a Baby Has a Fever,Treatment All Depends

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科技英语学习 2009年第1期 7-9页

作者： perri Klass 刘广霞

对发烧的婴儿，不同月龄有不同的治疗方法。不足一个月的婴儿需住院治疗，三个月以上的婴儿要验血或验尿，但不必住院。而对于一至三个月的婴儿，要验血或验尿乃至进行细菌培养，以确定是否有感染、是否需要注射抗生素或住院。

关键词：英语教学翻译方法译文教学方法

Head geometric morphometrics of two Chagas disease vectors from Venezuela

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Zoological Systematics 2017年第1期42卷 65-70页

作者： Ana Maria Oropeza Carlos Arturo perri Fernanndez Jonathan Liria Ana Soto-Vivas Escuela de Bioanalisis Facultad de Cieneias de la Salud Universidad de Carabobo Venezuela Universidad Regional Amazonica IKIAM km 7 via Muyuna Ecuador Centro de Esmdios en Zoologla Aplicada Facultad Experimental de Ciencias y Tecnologla Universidad de Carabobo Venezuela Centro de Estudios de Enfermedades Endkmicas y Salud Ambiental Institeto de Alto Estudios "Dr. Arnoldo Gabladon " Venezuela Carrera de Cs. Biologicas y Ambientales Facultad de Ciencias Biologicas Universidad Central del Ecuador Ecuador

Triatominae species are considered the main vectors of Chagas disease or American Trypanosomiasis. In Venezuela, the principal vectors are Rhodnius prolixus （Stal, 1959） and Triatoma maculata （Erichson, 1848）, which are belonged to the tribe Rhodniini and Triatomini, respectively. The head conformation and size development of these species can reflect ontogenetic changes which contribute with the vectors biology studies, as well to support of instars determination. The goal of the paper is to the application of geometric morphometric techniques for describing head conformation and size of instars of these species. We photographed 140 heads in R. prolixus： First instar （I： 16）, second instar （II： 17）, third instar （III： 18）, fourth instar （IV： 21）, fifth instar （V： 21）, adult female （F： 26） and adult males （M： 21）; in T. maculata heads of 136 specimens were photographed,I： 20, II： 17, III： 26, IV： 15, V： 19, F： 20 and M： 19. Landmark coordinate （x, y） configurations were registered and aligned by Generalized Procrustes Analysis. Covariance Analyses were implemented with proportions of re-classified groups and MANOVA. Statistical analyses of variance found not significant differences in head isometric size （Kruskal-Wallis） among IV and V instars in both species. The a posteriori re-classification was almost perfect in R. prolixus （82%） and T. maculata （86%）; the main head differences occurs in antenniferous tubercles, postocular and preocular. Our study using quantitative tools for describing the shape differences contributes to explain the morphology variability and development of Chagas disease vectors.

关键词： Instars Rhodniini Triatomini conformation centroid size.