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Unveiling mitochondrial mysteries:Exploring novel tRNA variants in type 2 diabetes mellitus

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World Journal of Diabetes 2025年第1期16卷 1-6页

作者： Chun-Han cheng Wen-Rui Hao Tzu-Hurng cheng Department of Medical Education Linkou Chang Gung Memorial HospitalTaoyuan 33305Taiwan Division of Cardiology Department of Internal MedicineShuang Ho HospitalMinistry of Health and WelfareTaipei Medical UniversityNew Taipei 23561Taiwan Division of Cardiology Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11002Taiwan Department of Biochemistry School of MedicineCollege of MedicineChina Medical UniversityTaichung 404328Taiwan

The recent study of Ding et al provides valuable insights into the functional implications of novel mitochondrial tRNATrp and tRNASer(AGY)variants in type 2 diabetes mellitus(T2DM).This editorial explores their findings,highlighting the role of mitochondrial dysfunction in the pathogenesis of *** examining the molecular mechanisms through which these tRNA variants contribute to disease progression,the study introduces new targets for therapeutic *** discuss the broader implications of these results,emphasizing the importance of understanding mitochondrial genetics in addressing T2DM.

关键词： Mitochondrial tRNA variants Type 2 diabetes mellitus Mitochondrial dysfunction Genetic markers Therapeutic strategies

Evaluation of The Interaction between Netropsin and Double Stranded DNA by Capillary Zone Electrophoresis

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Chinese Chemical Letters 2003年第3期14卷 304-307页

作者： Xin Ya HE da zhi LI Ai Ye LIANG Bing cheng LIN dalian Institute of Chemical Physics Chinese Academy of SciencesDalian 116023

Capillary zone electrophoresis (CZE) was applied to study the interaction between netropsin and a 14mer double stranded DNA (dsDNA). The binding constant of this interaction calculated from Scatchard plot was (1.070.10)×105 (mol/L)-1. The binding stoichiometry was 1:1. The use of polyacrylamide coated capillary showed better effect in the analysis of DNA than noncoated capillary.

关键词： Interaction netropsin DNA capillary zone electrophoresis.

Theoretical insights into efficient oxygen evolution reaction using non-noble metal single-atom catalysts on W_(2)CO_(2)MXene

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Rare Metals 2024年第10期43卷 5082-5094页

作者： Jing-Yu Zhou zhi-cheng Han Shu Zhao Tao Yang da-Zhou Yan Hai-Jun Yu Institute of Advanced Battery Materials and Devices College of Materials Science and EngineeringBeijing University of TechnologyBeijing 100124China Key Laboratory of Advanced Functional Materials Ministry of EducationBeijing University of TechnologyBeijing 100124CChhiinnaa China ENFI Engineering Corporation Beijing 100038China National Engineering Research Center of Silicon-Based Materials Manufacturing Technology Luoyang 471000China

The pursuit of highly active oxygen evolution reaction(OER)catalysts,especially those free of noble metals,is a focal point in fuel cell *** extensive density functional theory calculations,this study designed and evaluated the activity and stability of singleatom catalysts(SACs)composed of 3d,4d and 5d transition metals supported on tungsten-based MXene for OER *** highlighted the exceptional OER performance of Ni@W_(2)CO_(2),Rh@W_(2)CO_(2)and Pt@W_(2)CO_(2),displaying remarkably low overpotentials The catalytic activity of TM@W_(2)CO_(2)SACs exhibited a robust correlation with surface properties,particularly the d-band center index and surface work *** Ni@W_(2)CO_(2),Rh@W_(2)CO_(2)and Pt@W_(2)CO_(2)emerged as promising candidates for OER and oxygen reduction reaction(ORR)bifunctional catalysis,while Pt@W_(2)CO_(2)and Rh@W_(2)CO_(2)showed high potential for OER and hydrogen evolution reaction(HER)bifunctional catalysis The effectiveness of tungsten-based MXene as a substrate for non-noble-metal SACs marks a breakthrough in OER catalyst design,driving advancements towards sustainable energy solutions and addressing critical challenges in energy conversion and storage.

关键词： Oxygen evolution reaction Single-atom catalysts MXene Non-noble metal Density functional theory

Selenoprotein P1 as a biomarker of insulin resistance in pediatric obesity:Insights and implications

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World Journal of Clinical Pediatrics 2025年第1期14卷 1-5页

作者： Chun-Han cheng Wen-Rui Hao Tzu-Hurng cheng Department of Medical Education Linkou Chang Gung Memorial HospitalTaoyuan 33305TaiwanChina Division of Cardiology Department of Internal MedicineShuang Ho HospitalMinistry of Health and WelfareTaipei Medical UniversityNew Taipei 23561TaiwanChina Division of Cardiology Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11002TaiwanChina Department of Biochemistry School of MedicineCollege of MedicineChina Medical UniversityTaichung 404328TaiwanChina

This editorial discusses the findings of Elbarky et al on the role of selenoprotein P1(SEPP1)in pediatric obesity and insulin *** study uncovered si-gnificantly lower SEPP1 Levels in children who were obese compared with hea-lthy peers,demonstrating a negative correlation between SEPP1 levels and mea-sures of adiposity and insulin *** findings suggest that SEPP1 is a biomarker useful in the early identification of insulin resistance in pediatric *** editorial emphasizes the clinical implications of the study and calls for further research to validate and explore the role of SEPP1 in metabolic health.

关键词： Selenoprotein P1 Pediatric obesity Insulin resistance Biomarkers Metabolic health

Combining SVM and CHMM classifiers for porno video recognition

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The Journal of China Universities of Posts and Telecommunications 2012年第3期19卷 100-106页

作者： ZHAO zhi-cheng School of Information and Communication Engineering Beijing University of Posts and Telecommunications Beijing 100876 China Beijing Key Laboratory of Network System and Network Culture Beijing University of Posts and Telecommunications Beijing 100876 China

Pomo video recognition is important for Intemet content monitoring. In this paper, a novel pomo video recognition method by fusing the audio and video cues is proposed. Firstly, global color and texture features and local scale-invariant feature transform （SIFT） are extracted to train multiple support vector machine （SVM） classifiers for different erotic categories of image frames. And then, two continuous density hidden Markov models （CHMM） are built to recognize porno sounds. Finally, a fusion method based on Bayes rule is employed to combine the classification results by video and audio cues. The experimental results show that our model is better than six state-of-the-art methods.

关键词： pomo video recognition SVM keyframe CHMM audio

Radiomics and molecular analysis:Bridging the gap for predicting hepatocellular carcinoma prognosis

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World Journal of Clinical Cases 2025年第4期13卷 56-60页

This editorial examines a recent study that used radiomics based on computed tomography(CT)to predict the expression of the fibroblast-related gene enhancer of zeste homolog 2(EZH2)and its correlation with the survival of patients with hepatocellular carcinoma(HCC).By integrating radiomics with molecular analysis,the study presented a strategy for accurately predicting the expression of EZH2 from CT *** findings demonstrated a strong link between the radiomics model,EZH2 expression,and patient *** noninvasive approach provides valuable insights into the therapeutic management of HCC.

关键词： Hepatocellular carcinoma Computed tomography Radiomics Enhancer of zeste homologue 2 expression Non-invasive imaging

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冬虫夏草与蛹虫草菇中微量元素的比较

光谱实验室 2013年第2期30卷 779-781页

作者：韩涛程大志皮立李以康赵晓辉韩发周党卫中国科学院西北高原生物研究所高原生物适应与进化重点实验室西宁市西关大街59号810008 中国科学院研究生院北京市100049 中国科学院湖州高原生物资源产业化创新中心浙江省湖州市313000

以电感耦合等离子体-原子发射光谱法(ICP-AES)测定冬虫夏草与蛹虫草菇中微量元素的含量。方法的回收率在96.2%—101.7%之间,相对标准偏差小于或等于2.58%。实验证明,冬虫夏草与蛹虫草菇含有对人体有益的微量元素,除磷元素以外,蛹虫草菇... 详细信息

以电感耦合等离子体-原子发射光谱法(ICP-AES)测定冬虫夏草与蛹虫草菇中微量元素的含量。方法的回收率在96.2%—101.7%之间,相对标准偏差小于或等于2.58%。实验证明,冬虫夏草与蛹虫草菇含有对人体有益的微量元素,除磷元素以外,蛹虫草菇中其他元素含量均低于冬虫夏草。

关键词：电感耦合等离子体-原子发射光谱法冬虫夏草蛹虫草菇微量元素

Special issue on selected papers from HVDP 2016

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Plasma Science and Technology 2017年第6期19卷 1-2页

作者： zhi FANG cheng cheng College of Electrical Engineering and Control Science Nanjing Tech University Institute of Plasma Physics Chinese Academy of Sciences

This special issue contains selected papers from the 2016 National Conference on High Voltage and Discharge Plasmas（HVDP）,which was hosted by the Plasmas and their Applications Committee,China Electrotechnical Society,and held in Beijing,China,on 26 and 27 November *** conference was attended by over 430 delegates from 110 universities,research institutes and *** total,280 abstracts and 132 full papers have been submitted,giving a wonderful assembly of technical contributions from around China.

关键词： this Special issue on selected papers from HVDP 2016

Preparation and compression behavior of Fe-Ni-P/porous-Fe/Fe-Ni-P composites

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Journal of Iron and Steel Research International 2022年第8期29卷 1334-1341页

作者： Yu-xuan Liu Shuai-jiang Yan cheng-song Zhang da-zhi Chen Qin Xu Guo-dong Cui Key Lab of Advanced Technology of Materials of Education Ministry School of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031SichuanChina Yibin Institute of Southwest Jiaotong University Yibin 644000SichuanChina

Porous-Fe-N alloys designed for light weight or energy absorption are inevitably facing the compromise of deteriorated mechanical properties. To optimize their mechanical properties, here a novel Fe-Ni-P/porous-Fe/Fe-Ni-P composite with sandwich structure was fabricated by spark plasma sintering and further strengthened via cryogenic treatment. Based on the principle of solid phase sintering and transient liquid phase sintering, porous core and dense outer layers formed simultaneously after co-sintering. The as-fabricated samples show excellent compressive strength of 1708 MPa, and after cryogenic treatment, due to the sufficient martensitic transformation, Fe-Ni-P outer layers show substantially increased hardness from 246.7 to 386.6 HV_(0.1)while the porous-Fe core remains unchanged. And the compressive strength maintains 1424 MPa despise the aggravated incongruity of deformation. The ratio of constituent microhardness R has been proposed to represent the hardness matching, and with decreasing R, the incongruity of deformation is intensified, and the nominal compressive strength is reduced.

关键词： Metallic composite Sandwich structure Spark plasma sintering Mechanical property