检索结果-南通市图书馆

Tumor necrosis factor-stimulated gene-6 ameliorates early brain injury after subarachnoid hemorrhage by sup.r.ssing NLrC4 inflammasome-mediated astrocyte p.r.ptosis

引用

Neural regeneration research 2024年第5期19卷 1064-1071页

作者： Mingxiang Ding Lei Jin Boyang Wei Wenping cheng Wenchao Liu Xifeng Li Chuanzhi Duan Neurosurgery Center Department of Cerebrovascular SurgeryThe National Key Clinical SpecialtyThe Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular DiseaseGuangdong Provincial Key Laboratory on Brain Function Repair and RegenerationThe Neurosurgery Institute of Guangdong ProvinceZhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina department of Cerebrovascular Intervention Zhongshan City People’s HospitalZhongshanGuangdong ProvinceChina

Subarachnoid hemorrhage is associated with high morbidity and mortality and lacks effective *** is a crucial mechanism underlying early brain injury after subarachnoid *** studies have confirmed that tumor necrosis factor-stimulated gene-6(TSG-6)can exert a neuroprotective effect by sup.r.ssing oxidative stress and ***,no study to date has explored whether TSG-6 can alleviate p.r.ptosis in early brain injury after subarachnoid *** this study,a C57BL/6J mouse model of subarachnoid hemorrhage was established using the endovascular p.r.oration *** results indicated that TSG-6 expression was predominantly detected in astrocytes,along with NLrC4 and gasdermin-D(GSDMD).The expression of NLrC4,GSDMD and its N-terminal domain(GSDMD-N),and cleaved caspase-1 was significantly enhanced after subarachnoid hemorrhage and accompanied by brain edema and neurological *** explore how TSG-6 affects p.r.ptosis during early brain injury after subarachnoid hemorrhage,recombinant human TSG-6 or a sirNA targeting TSG-6 was injected into the cerebral *** TSG-6 administration downregulated the expression of NLrC4 and p.r.ptosis-associated proteins and alleviated brain edema and neurological ***,TSG-6 knockdown further increased the expression of NLrC4,which was accompanied by more severe astrocyte *** summary,our study revealed that TSG-6 provides neuroprotection against early brain injury after subarachnoid hemorrhage by sup.r.ssing NLrC4 inflammasome activation-induced astrocyte p.r.ptosis.

关键词： astrocyte early brain injury inflammasome NLrC4 p.r.ptosis subarachnoid hemorrhage tumor necrosis factor-stimulated gene-6(TSG-6)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

regulating electrochemical p.r.ormances of lithium battery by external physical field

引用

rare Metals 2024年第6期43卷 2391-2417页

作者： Shi-Kang Wang Shuai Wu Yi-cheng Song Hassanien Gomaa Cui-Hua An Qi-Bo Deng Ning Hu School of Mechanical Engineering School of Materials Science and EngineeringHebei University of TechnologyTianjin 300401China Shanghai Key Laboratory of mechanics in Energy Engineering Shanghai 200444China department of Chemistry Faculty of ScienceAl-Azhar UniversityAssiut 71524Egypt Tianjin Key Laboratory of power Transmission and Safety Technology for New Energy Vehicles Tianjin 300401China State Key Laboratory of reliability and Intelligence Electrical Equipment Key Laboratory of Advanced Intelligent Protective Equipment TechnologyMinistry of EducationHebei University of TechnologyTianjin 300130China

Lithium batteries have always played a key role in the field of new energy ***,non-controllable lithium dendrites and volume dilatation of metallic lithium in batteries with lithium metal as anodes have limited their ***,a large number of studies have shown that the electrochemical p.r.ormances of lithium batteries can be enhanced through the regulation of external physical ***,it significantly hinders the growth of lithium dendrites and promoting the reaction *** review summarizes recent innovations in the investigation of various physical fields of lithium *** application of magnetic field in the synthesis of lithium battery electrode materials is *** influence factors and regulation mechanism of various physical fields on the electrochemical p.r.ormance of lithium batteries are reviewed *** addition,the current research status and existing challenges,along with future directions for the evolution of lithium batteries,are minutely discussed and *** strategies for the further evolution of lithium batteries have also been provided.

关键词： Lithium battery External field assist reaction kinetics Lithium dendrite

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

消干效应和量子力学新解释的意义

引用

物理 2002年第3期31卷 179-184页

作者：关洪中山大学物理系广州510275

简单介绍了消干 (decoherence)效应以及量子力学的一种新解释———由Griffiths,Gell Mann和Omn埁ｓ等独立提出的“消干历史解释”的由来和要点 ,评述了这一进展在量子理论发展中的意义 .

关键词：量子力学消干效应路径积分法经典物理学

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Subsurface multi-physical characterization of mountain excavation and city construction in loess plateau with a fiber-optic sensing system

引用

Journal of rock mechanics and Geotechnical Engineering 2024年第8期16卷 2935-2946页

作者： Jie Liu Bin Shi Kai Gu Meng-Ya Sun Jun-cheng Yao He-Ming Han School of Earth Sciences and Engineering Nanjing UniversityNanjingJiangsu210023China Frontiers Science Center for Critical Earth Material Cycling Nanjing UniversityNanjing210023China School of Earth Sciences and Engineering Hohai UniversityNanjing210098China

Mountain excavation and city construction(MECC)projects being launched in the Loess plateau in china involve the creation of large-scale artificial *** the subsurface evolution characteristics of the artificial land is essential,yet ***,we use an improved fiber-optic monitoring system for its subsurface multi-physical *** system enables us to gather spatiotemp.r.l distribution of various p.r.meters,including strata deformation,temp.r.ture,and ***’an New District was selected as a case study to conduct refined in-situ monitoring through a 77 m-deep borehole and a 30 m-long *** reveal that the ground settlement involves both the deformation of the filling loess and the underlying intact ***,the filling loess exhibits a stronger creep capability comp.r.d to underlying intact *** deformation along the profile is unevenly distributed,with a positive correlation with soil *** accumulation has been observed at the interface between the filling loess and the underlying intact loess,leading to a significant ***,the temp.r.ture and moisture in the filling loess have reached a new equilibrium state,with their depths influenced by atmospheric conditions measuring at 31 m and 26 m,*** refined investigation allows us to identify critical layers that matter the sustainable development of newly created urban areas,and provide improved insights into the evolution mechanisms of land creation.

关键词： Mountain excavation and city construction Fiber-optic monitoring Multi-physical characterization Compacted loess

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Study of relationships between the Damage of Visual Function and Hemorrheology, Ocular rheography, as well as Other related Factors in patients with primary Open Angle Glaucoma (pOAG)

引用

眼科学报 1993年第1期9卷 3-11页

作者： Jian Ge, Wenbing Zhou National Ophthalmological Laboratories, Ministry of public Health, china, zhongshan Ophthalmic Center, Sun Yat-Sen university of Medical Sciences, guangzhou 510060, china Jiancu Zhu, Anheng cheng, Yulan Lin, Hongyan Tong, Lin Lian, Zhixing Chen Institute of Cardiovascular Diseases of Guangdong province, guangzhou 510080, china National Ophthalmological Laboratories Ministry of Public Health China.

researches of glaucoma visual function damage, hemorrheololgy, ocular rheography and other related multiplex factors, with computed multifactorial stepwise regresion analysis, indicate that the elevation of intraocular pressure (IOp) is not the only factor to induce visual impairment. pOAG patients are shown to have markedly reduced diastolic p.r.ussion pressure in ophthalmic artery, besides prolonged filling time of the retinal artery and vein, diminished erythrocyte deformability and increased platele...

关键词： visual function hemorrheology primary open angle glaucoma (pOAG) ocular rehography intraocular pressure (IOp) blood cells trace elements multiphy stepwise regression.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Numerical Analysis of Cold-Formed Thin-Walled Steel Short Columns with pitting Corrosion during Bridge Construction

引用

Structural Durability & Health Monitoring 2024年第2期18卷 181-196页

作者： Hongzhang Wang Jing Guo Shanjun Yang Chaoheng cheng Jing Chen Zhihao Chen CCCC Second Harbor Engineering Third Engineering Co. Ltd.Zhenjiang212000China Suqian Highway Development Center Suqian223800China School of mechanics and Civil Engineering China University of Mining and TechnologyXuzhou221116China

pitting corrosion is harmful during bridge construction,which will lead to uneven roughness of steel surfaces and reduce the thickness of ***,the effect of pitting corrosion on the mechanical prop.r.ies of cold-formed thin-walled steel stub columns is studied,and the emp.r.cal formulas are established through regression fitting to predict the ultimate load of web and flange under pitting *** detail,the failure modes and load-displacement curves of specimens with different locations,area ratios,and depths are obtained through a large number of non-linear finite element *** for the specimens with pitting corrosion on the web,all the specimens are subject to local buckling failure,and the failure mode will not change with pitting corrosion,but the failure location will change with pitting corrosion location;the size,location,and area ratio of pitting corrosion have little influence on the ultimate load of cold-formed thin-walled steel short columns,but the loss rate of pitting corrosion section area has a greater impact on the ultimate bearing *** for the specimen with flange pitting corrosion,the location and area ratio of pitting corrosion have less influence on the ultimate load of cold-formed thin-walled steel short columns,and the section area loss rate has greater influence on the ultimate bearing capacity;the impact of web pitting corrosion on the ultimate load is greater than that of flange pitting corrosion under the same condition of pitting corrosion section *** prediction formulas of limit load which are suitable for pitting corrosion of web and flange are established,which can provide a reference for p.r.ormance evaluation of corroded cold-formed thin-walled steel.

关键词： pitting corrosion cold-formed thin-walled steel ultimate load prediction formula short columns

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Novel Accurate Method forMulti-Term Time-Fractional Nonlinear Diffusion Equations in Arbitrary Domains

引用

Computer Modeling in Engineering & Sciences 2024年第2期138卷 1521-1548页

作者： Tao Hu cheng Huang Sergiy reutskiy Jun Lu Ji Lin Ningbo Yongxin Engineering Consulting Co. Ltd.Ningbo315042China Taizhou HuanfengWater Conservancy Engineering Co. Ltd.Taizhou318050China A.pidhornyi Institute of Mechanical Engineering problems National Academy of Sciences of UkraineKharkiv61046Ukraine Material and Structure department Nanjing Hydraulic Research InstituteNanjing210029China College of mechanics and Materials Hohai UniversityNanjing211100China

Anovel accuratemethod is proposed to solve a broad variety of linear and nonlinear(1+1)-dimensional and(2+1)-dimensional multi-term time-fractional p.r.ial differential equations with spatial op.r.tors of anisotropic ***(1+1)-dimensional problems,analytical solutions that satisfy the boundary requirements are *** solutions are numerically calculated using the trigonometric basis ap.r.ximation for(2+1)-dimensional *** the aid of these analytical or numerical ap.r.ximations,the original problems can be converted into the fractional ordinary differential equations,and solutions to the fractional ordinary differential equations are ap.r.ximated by modified radial basis functions with time-dependent *** efficient backward substitution strategy that was previously provided for a single fractional ordinary differential equation is then used to solve the corresponding *** straightforward quasilinearization technique is applied to handle nonlinear *** exp.r.ments demonstrate the suggested algorithm’s sup.r.or accuracy and efficiency.

关键词： Müntz polynomial basis backward substitutionmethod collocationmethod meshlessmethod fractional equation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Information of Black Hole-Inner Disk System predicted by Fe Lines in Seyfert(-like)AGNs

Information of Black Hole-Inner Disk System Predicted by Fe ...

引用

黑洞物理研讨会

作者： MA Zhenguo BAO Yun Solar Magnetic Field & Activities Group, National Astronomical Observatories, Chinese Academy of Sciences, Beijing, china department of mechanics, zhongshan university, guangzhou, china

1. Introduction Albert Einstein’s Gr theory predicted that rotating bodies, such as BHs, drag the 4-D spacetime of the curved inertial frames, called Frame Dragging (FD), around itself as it rotates. The effect results in a new quasi-magnetic field, named as gravitomagnetic field, as a variant of the conventional gravitational field described by the simpler math of Sir Isaac Newton. The exotic field can be so strong that it not only is possible to rival the old one in strength but can radiate discernible gravitational waves as well. Just as a moving charge (an electrical current) causes an ordinary magnetic field by Amp.r.’s law

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Thermo-hydro-p.r.-mechanical responses of a reservoir-induced landslide tracked by high-resolution fiber optic sensing nerves

引用

Journal of rock mechanics and Geotechnical Engineering 2024年第3期16卷 1018-1032页

作者： Xiao Ye Hong-Hu Zhu Gang cheng Hua-Fu pei Bin Shi Luca Schenato Alessandro pasuto School of Earth Sciences and Engineering Nanjing UniversityNanjing210023China School of Computer Science North China Institute of Science and Technology(National Safety Training Center of Coal Mines)Beijing101601China State Key Lab of Coastal and Offshore Engineering Department of Geotechnical EngineeringDalian University of TechnologyDalian116024China National research Council-research Institute for Geo-Hydrological protection(CNr-IrpI) Padova35127Italy department of Information Engineering University of PadovaPadova35131Italy

Thermo-p.r.-mechanical responses along sliding zone/surface have been extensively ***,it has not been recognized that the potential contribution of other crucial engineering geological interfaces beyond the slip surface to progressive ***,we aim to investigate the subsurface multiphysics of reservoir landslides under two extreme hydrologic conditions(*** and dry),p.r.icularly within sliding *** on ultra-weak fiber Bragg grating(UWFBG)technology,we employ specialp.r.ose fiber optic sensing cables that can be implanted into boreholes as“nerves of the Earth”to collect data on soil temp.r.ture,water content,p.r. water pressure,and *** Xinpu landslide in the middle reach of the Three Gorges reservoir Area in china was selected as a case study to establish a p.r.digm for in situ thermo-hydro-p.r.-mechanical *** UWFBG-based sensing cables were vertically buried in a 31 m-deep borehole at the foot of the landslide,with a resolution of 1 m except for the pressure *** rep.r.ed field measurements covering the p.r.od 2021 and 2022 and produced the spatiotemp.r.l profiles throughout the *** show that wet years are more likely to motivate landslide motions than dry *** annual thermally active layer of the landslide has a critical depth of roughly 9 m and might move downward in warmer *** dynamic groundwater table is located at depths of 9e15 m,where the peaked strain undergoes a p.r.odical response of leap and withdrawal to annual hydrometeorological *** interface behaviors may supp.r. the interpretation of the contribution of reservoir regulation to slope stability,allowing us to correlate them to local damage events and potential global *** pap.r.also offers a natural framework for interpreting thermo-hydro-p.r.-mechanical signatures from creeping reservoir bank slopes,which may form the basis for a landslide monitoring and early warning system.

关键词： reservoir landslide Thermo-hydro-p.r.-mechanical response Ultra-weak fiber bragg grating(UWFBG) subsurface evolution Engineering geological interface Geotechnical monitoring

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

趋势种种——图书馆数字化网络化研究札记

引用

图书馆论坛 2001年第2期21卷 17-18,40页

作者：程焕文中山大学信息管理系广州510275

文章认为近年来图书馆的主要发展和趋势包括馆藏数字化、业务网络化、技术商业化、馆员参考化、合作全球化、服务人性化、发展两极分化等七个方面 ,分析了图书馆发展变化的特点。

关键词：图书馆数字化图书馆网络化图书馆发展趋势馆际合作全球化

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：