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Chinese Journal of Cancer Research 2023年第5期35卷 483-500页

作者： shuping cheng Butuo Li Jinming Yu Linlin Wang Department of Radiation Oncology Shandong Cancer Hospital Affiliated to Shandong First Medical UniversityJinan 250117China Department of Radiation Oncology and Shandong Provincial Key Laboratory of Radiation Oncology Shandong Cancer Hospital and InstituteShandong First Medical University and Shandong Academy of Medical SciencesJinan 250117China Research Unit of Radiation Oncology Chinese Academy of Medical SciencesJinan 250117China

Esophageal cancer usually has a poor *** the significant breakthrough with tumor immunotherapy,an increasing number of clinical studies have demonstrated that the combination of radiotherapy and immune checkpoint inhibitors(ICIs)may have a synergistic effect and good outcome in esophageal *** studies of immunoradiotherapy(iRT)for esophageal cancer have proliferated enormously from 2021 to the ***,a summary of the efficacy and toxicity of combined therapy to guide esophageal cancer treatment in clinical practice is *** this review,we integrate the latest data to analyze and assess the efficacy and safety of iRT for esophageal *** addition,we discuss better predictive biomarkers,therapeutic options for specific populations,and other challenges to identify directions for future research design.

关键词： Esophageal cancer immunoradiotherapy combination therapies

氯胺酮和依托咪酯用于快速顺序插管的有效性与安全性的Meta分析

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实用临床医药杂志 2024年第9期28卷 82-89页

作者：程书平何佩柳远飞吴利东南昌大学第二附属医院急诊科江西南昌330200 南昌大学第一附属医院康复科江西南昌330006

目的比较氯胺酮和依托咪酯在快速顺序插管(RSI)中的有效性和安全性。方法通过计算机检索中国知网、万方数据、维普、PubMed、Embase、Cochrane图书馆、***建库至2023年5月1日发表的有关于氯胺酮和依托咪酯用于急危重症患者RSI的随机... 详细信息

目的比较氯胺酮和依托咪酯在快速顺序插管(RSI)中的有效性和安全性。方法通过计算机检索中国知网、万方数据、维普、PubMed、Embase、Cochrane图书馆、***建库至2023年5月1日发表的有关于氯胺酮和依托咪酯用于急危重症患者RSI的随机对照实验(RCT)和队列研究。根据纳入和排除标准对文献进行筛选,并对文献进行数据提取和质量评估。采用RevMan 5.3软件进行Meta分析。结果最终纳入15篇文献,共计20 839例患者,包括3项RCT和12项队列研究。Meta分析结果显示,与依托咪酯组相比,氯胺酮组的首次插管成功率(RR=0.99, 95%CI:0.98~1.00,P=0.10)、心脏骤停发生率(RR=1.00, 95%CI:0.62~1.62,P=0.99)、机械通气时间(MD=0.33, 95%CI:-0.34~1.01,P=0.33)、病死率(RR=1.05, 95%CI:0.95~1.16,P=0.31)均无显著差异,肾上腺皮质功能不全发生率显著降低(RR=0.54, 95%CI:0.41~0.70,P<0.001), ICU住院时间显著缩短(MD=-0.44, 95%CI:-0.70~-0.18,P=0.001),但低氧血症发生率显著升高(RR=1.50, 95%CI:1.27~1.79,P<0.001)。结论在充分预给氧的RSI过程中,氯胺酮是一种安全有效的替代药物,相比于依托咪酯,其肾上腺皮质功能不全的发生率更低,可以缩短ICU住院时间。

关键词：氯胺酮依托咪酯快速顺序插管首次插管成功率肾上腺皮质功能不全 Meta分析

Spatial diversity and combination technology using amplitude and phase weighting method for phase-coherent underwater acoustic communications

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Chinese Journal of Acoustics 2018年第1期37卷 45-59页

作者： LI Jilong HUANG Minyan cheng shuping TAN Qianlin FENG Haihong University of Chinese Academy of Sciences Beijing 100049 Institute of Acoustics Chinese Academy of Sciences Beijing 100190 ShangHai Acoustics Laboratory Chinese Academy of Sciences Shanghai 200032

The UWA channel is characterized as a time-dispersive rapidly fading channel, which in addition exhibits Doppler instabilities and limited bandwidth. To eliminate inter- symbol interference caused by multipath propagation, spatial diversity equalization is the main technical means. The paper combines the passive phase conjugation and spatial processing to maximize the output array gain. It uses signal-to-noise-plus-interference to evaluate the quality of signals received at different channels. The amplitude of signal is weighted using Sigmoid function. Second order PLL can trace the phase variation caused by channel, so the signal can be accumulated in the same phase. The signals received at different channels need to be normal- ized. It adopts fractional-decision feedback diversity equalizer （FDFDE） and achieves diversity equalization by using different channel weighted coefficients. The simulation and lake trial data processing results show that, the optimized diversity receiving equalization algorithm can im- prove communication system＇s ability in tracking the change of underwater acoustic channel, offset the impact of multipath and noise and improve the performance of communication system. The performance of the communication receiving system is better than that of the equal gain combination. At the same time, the bit error rate （BER） reduces 1.8%.

关键词： SNR BER Spatial diversity and combination technology using amplitude and phase weighting method for phase-coherent underwater acoustic communications SDE

High-safety and high-voltage lithium metal batteries enabled by nonflammable diluted highly concentrated electrolyte

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Nano Research 2024年第4期17卷 2638-2645页

作者： Han Zhang Ziqi Zeng shuping Wang Yuanke Wu Changhao Li Mengchuang Liu Xinlan Wang Shijie cheng Jia Xie State Key Laboratory of Materials Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic EngineeringHuazhong University of Science and TechnologyWuhan 430074China State Grid Anhui Electric Power Research Institute Anhui Province Key Laboratory of Electric Fire and Safety Protection(State Grid Laboratory of Fire Protection for Transmission and Distribution Facilities)Hefei 230601China School of Chemistry and Chemical Engineering Huazhong University of Science and TechnologyWuhan 430074China

Lithium metal batteries(LMBs)show great promise for achieving energy densities over 400 Wh·kg^(-1).However,highly flammable organic electrolytes are a long-lasting problem that triggers safety hazards and hinders the commercial application of ***,a nonflammable diluted highly concentrated electrolyte(DHCE)with ethoxy(pentafluoro)cyclotriphosphazene(PFPN)as a diluent is developed to simultaneously achieve high safety and cycling stability of high-voltage *** optimal DHCE not only ensures reversible Li deposition/dissolution behavior with a superior average Coulombic efficiency(CE)over 99.1%on lithium metal anode(LMA),but also suppresses side reactions and stress crack on the LiCoO_(2)(LCO)under high cut-off *** newly developed DHCE exhibits high thermal stability,showing complete nonflammability and reduced heat generation between the electrolyte and delithiated LCO/cycled *** work offers an opportunity for rational designing nonflammable electrolytes toward high-voltage and safe LMBs.

关键词： lithium metal batteries thermal stability nonflammable electrolyte high-voltage phosphazene

Policy iteration-based adaptive optimal control for Markov jump systems: a transition-probability-free asynchronous approach

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Science China(Information Sciences) 2024年第11期67卷 363-364页

作者： Weidi cheng chengcheng REN shuping HE Changyin SUN Key Laboratory of Intelligent Computing and Signal Processing (Ministry of Education) School of Electrical Engineering and Automation Anhui University Anhui Engineering Laboratory of Human-Robot Integration System and Intelligent Equipment School of Electrical Engineering and Automation Anhui University Information Materials and Intelligent Sensing Laboratory of Anhui Province Engineering Research Center of Autonomous Unmanned System Technology (Ministry of Education) School of Artificial Intelligence Anhui University

The controller and filter design problems of Markov jump systems(MJSs) have gained significant attention over the past few decades. These studies include various aspects,including stochastic stabilization [1], optimal tracking control [2], and dissipative filter design [3]. Although numerous publications address the optimal controller design for MJSs, the issue of hidden MJSs, particularly those with mismatched jumping modes between the system and the controller, has rarely been explored.

关键词：

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Seven amino acid peptide mimic from HVR1 of HCV influences cytokine profile of immune cells

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Journal of Medical Colleges of PLA(China) 2010年第5期25卷 257-266页

作者： Song Chunhui Chen Liming Yang Bin Chi shuping cheng Yun Department of Liver Disease Research Center for Biology No. 302 Hospital of PLA Beijing 100039 China

Objective:To investigate the actions of cytokine profile in the immune cells by a seven amino acid peptide mimic from HVR1 of HCV (GQTYTSG,named 7P).Methods:The peripheral blood mononuclear cells (PBMCs) from 17 healthy blood donors were stimulated with 7P,and the cytokine levels in CD4+CD8-,CD4-CD8+ T cells,NK,NKT cells were analyzed by the intracellular cytokine ***:The frequency of cells which secreted interferon-γ (IFN-γ) was found to be significantly increased in all cells,interleukin-10(IL-10) was significantly increased in CD4+CD8-,CD4-CD8+ T cells but decreased in NK,NKT cells,and tumor necrosis factor-α (TNF-α) was decreased in CD4+CD8-,CD4-CD8+ but increased in NK ***:7P could induce a cytokine profile in different immune cells in vitro and there was some difference between the CD4+CD8-,CD4-CD8+ T cells which represented the adaptive immunity cells and NK,NKT cells which represented the innate immunity *** kind of variation of cytokine profile might contribute to anti-virus and anti-inflammatory immune reaction.

关键词： Seven amino acids peptide mimic Interleukin-lO Interferon-γ Tumor necrosis factor-α Hepatitis C virus

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对日本企业融资方式及其治理结构的反思

现代日本经济 2001年第4期118卷 41-44页

作者：程书萍郑垂勇河海大学技术经济学院江苏南京210098

日本企业采用的是银行主导型融资方式，并由此产生主银行内部控制型的企业治理结构模式。这种曾经促使日本经济快速腾飞的融资模式和治理结构是目前日本难以摆脱困境的根本原因。目前我国国有企业融资应采用“间接融资为主、直接融资为... 详细信息

日本企业采用的是银行主导型融资方式，并由此产生主银行内部控制型的企业治理结构模式。这种曾经促使日本经济快速腾飞的融资模式和治理结构是目前日本难以摆脱困境的根本原因。目前我国国有企业融资应采用“间接融资为主、直接融资为辅”的方式，其治理结构为证券市场、银行制度、融资结构“三位一体”的方式。

关键词：融资方式股权结构治理结构日本企业

基于政府多重功能分析的重大工程“激励-监管”治理模型

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系统管理学报 2018年第1期27卷 129-136,156页

作者：邱聿旻程书萍南京大学工程管理学院南京210093

在我国,政府深度参与重大工程建设各个阶段,承担多重的、动态的重要功能,不同阶段的不同功能影响着重大工程治理体系的构建以及社会效益的实现。构建相互独立、权责清晰的建设主体和监管主体,能够充分发挥政府监管作用,保证治理的科学... 详细信息

在我国,政府深度参与重大工程建设各个阶段,承担多重的、动态的重要功能,不同阶段的不同功能影响着重大工程治理体系的构建以及社会效益的实现。构建相互独立、权责清晰的建设主体和监管主体,能够充分发挥政府监管作用,保证治理的科学性。从政府承担的不同功能入手来探讨重大工程治理问题,创新性地提出一个以政府为主导的"政府式委托代理"治理结构,并在此基础上构建"激励-监管"治理模型,对比有无监管条件下的帕累托最优解,并结合数值分析进行验证。结果表明,有效的政府监管能够显著提升建设主体努力水平和工程整体效益,且随着监管主体监管水平的提高,能够有效降低工程风险。尤其对于重大工程这一类具有复杂性、深度不确定性的高风险工程而言,较高的监管水平能够有效防治工程风险,提升工程整体社会效益。政府应当努力提升治理能力,通过科学手段引导重大工程相关行业提升创新能力,促进社会进步。

关键词：重大基础设施工程政府委托代理 “激励-监管”模型政府监管政府多重功能

投资者关系管理:改善公司治理提升公司价值的有效工具

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生产力研究 2006年第6期 208-210页

作者：杨义灿程书萍南京大学商学院南京大学工程管理学院江苏南京210093

投资者关系管理通过充分的信息披露,促进投资者对公司的了解和认同,以求保持公司经营的透明度、强化在资本市场的良好形象,实现公司价值最大化的战略管理行为。随着我国证券市场的日益成熟和规范,加强投资者关系管理,必将成为改善我国... 详细信息

投资者关系管理通过充分的信息披露,促进投资者对公司的了解和认同,以求保持公司经营的透明度、强化在资本市场的良好形象,实现公司价值最大化的战略管理行为。随着我国证券市场的日益成熟和规范,加强投资者关系管理,必将成为改善我国公司治理结构、提升上市公司价值的有效工具。

关键词：投资者关系管理公司治理结构价值最大化

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新生代农民工信息获取行为关键影响因素分析

中国农业资源与区划 2019年第11期40卷 103-110页

作者：程淑平孟令杰程业炳南京理工大学经济管理学院安徽科技学院管理学院

[目的]针对新生代农民工信息获取行为受多种因素交互影响的问题,提出了一种基于模糊数学和DEMATEL耦合的量化分析方法。[方法]首先,以社会认知理论为基础,从个体因素、信息源因素、环境因素3个方面构建新生代农民工信息获取行为影响因... 详细信息

[目的]针对新生代农民工信息获取行为受多种因素交互影响的问题,提出了一种基于模糊数学和DEMATEL耦合的量化分析方法。[方法]首先,以社会认知理论为基础,从个体因素、信息源因素、环境因素3个方面构建新生代农民工信息获取行为影响因素指标体系,然后运用三角模糊数表征因素间的关联程度,再通过实证调研,利用DEMATEL方法进行结果分析。[结果](1)个体因素类的F1、F3、F4、F6、F7,环境因素类的F14、F15为原因组因素;个体因素类的F2、F5,信息源因素类的F8、F9、F10,环境因素类的F11、F12、F13为结果组因素;(2)以中心度为基础,进行综合分析,得出新生代农民工信息获取行为关键影响因素分别是原因组的F1、F14、F6、F15和结果组的F10、F8、F12。[结论]原因组关键影响因素易对其他因素产生影响,从长期来看,应优先考虑对其进行提升或投资,结果组关键影响因素易于受到其他因素的影响,且对新生代农民工信息获取行为的作用最为直接,因此可以采取适当的管理措施进行调整和控制。

关键词：新生代农民工信息获取模糊数学 DEMATEL 影响因素