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Latest developments in EUV photoresist evaluation capability at Shanghai Synchrotron Radiation Facility

Nuclear Science and Techniques 2023年第12期34卷 206-215页

作者： Zhen‑Jiang Li cheng‑hang Qi Bei‑Ning Li Shu‑Min Yang Jun Zhao Zhi‑Di Lei Shi‑Jie Zhu Hao Shi Lu Wang Yan‑Qing Wu Ren‑Zhong Tai Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Sciences Beijing 100049China Shanghai Synchrotron Radiation Facility Shanghai 201204China ShanghaiTech University Shanghai 201210China Key Laboratory of Materials for High Power Lasers Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China College of Materials Science and Opto‑Electronic Technology University of Chinese Academy of SciencesBeijing 100083China Shanghai University Shanghai 200444China

Evaluating the comprehensive characteristics of extreme ultraviolet(EUV)photoresists is crucial for their application in EUV lithography,a key process in modern *** paper highlights the capabilities of the Shanghai Synchrotron Radiation Facility(SSRF)08U1B beamline in advancing this ***,it demonstrates how this beamline can create fringe patterns with a 15-nm half-pitch on a resist using synchrotron-based EUV *** achievement is vital for evaluating EUV photoresists at the advanced 5-nm *** provide a detailed introduction to the methods and experimental setup used at the SSRF 08U1B beamline to assess an EUV photoresist.A significant part of this research involved the fabrication of high-resolution hydrogen silsesquioxane mask *** gratings,with an aspect ratio of approximately 3,were created using electron beam lithography on an innovative mask *** framework was crucial in eliminating the impact of zeroth-order light on interference *** proposed framework propose offers a new approach to mask fabrication,particularly beneficial for achromatic Talbot lithography and multicoherent-beam interference applications.

关键词： Extreme ultraviolet photoresist Interference lithography High-resolution Electron beam lithography·Hydrogen silsesquioxane Grating

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工作模态分析在减速器监测和诊断中的应用

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振动．测试与诊断 2010年第2期30卷 197-200页

作者：程珩赵远太原理工大学机械电子研究所太原030024

针对当前机械传动系统的故障多发现象,开展了关于运行传动系统中减速器故障提取和定位方法的研究。根据运行减速器故障的特征信息,对其进行工作模态分析,并构造出故障频率处的广义振型,实现了设备故障的提取和定位。此方法突破了传统的... 详细信息

针对当前机械传动系统的故障多发现象,开展了关于运行传动系统中减速器故障提取和定位方法的研究。根据运行减速器故障的特征信息,对其进行工作模态分析,并构造出故障频率处的广义振型,实现了设备故障的提取和定位。此方法突破了传统的测试与诊断方法,为在工况下对设备状态进行监测和故障诊断提供了一条新途径。

关键词：工作模态减速器状态监测故障诊断

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Dual-objective two-photon microscope for volumetric imaging of dense scattering biological samples by bidirectional excitation and collection

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Photonics Research 2024年第6期12卷 1351-1361页

作者： MUYUE ZHAI JING YU YANHUI HU hang YU BEICHEN XIE YI YU DAWEI LI AIMIN WANG HEPING cheng National Biomedical Imaging Center College of Future TechnologyPeking UniversityBeijing 100871China Research Unit of Mitochondria in Brain Diseases Chinese Academy of Medical SciencesPKU-Nanjing Institute of Translational MedicineNanjing 211500China Beijing Transcend Vivoscope Biotech Beijing 100085China College of Engineering Peking UniversityBeijing 100871China Academy for Advanced Interdisciplinary Studies Peking UniversityBeijing 100871China Center for Quantitative Biology Peking UniversityBeijing 100871China School of Electronics Peking UniversityBeijing 100871China State Key Laboratory of Advanced Optical Communication System and Networks Peking UniversityBeijing 100871China

Full view observation throughout entire specimens over a prolonged period is crucial when exploring the physiological functions and system-level ***-photon microscopy(MPM)has been widely employed for such purposes owing to its deep penetration ***,the current MPM struggles with balancing the imaging depth and quality while avoiding photodamage for the exponential increasement of excitation power with the imaging ***,we present a dual-objective two-photon microscope(Duo-2P),characterized by bidirectional two-photon excitation and fluorescence collection,for long-duration volumetric imaging of dense scattering ***-2P effectively doubles the imaging depth,reduces the total excitation energy by an order of magnitude for samples with a thickness five times the scattering length,and enhances the signal-to-noise ratio up to 1.4 *** these advantages,we acquired volumetric images of a 380-μm suprachiasmatic nucleus slice for continuous 4-h recording at a rate of 1.67 s/volume,visualized the calcium activities over 4000 neurons,and uncovered their state-switching *** conclude that Duo-2P provides an elegant and powerful means to overcome the fundamental depth limit while mitigating photodamages for deep tissue volumetric imaging.

关键词： excitation overcome exponential

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Differential expression and significance of 5-hydroxymethylcytosine modification in hepatitis B virus carriers and patients with liver cirrhosis and liver cancer

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World Journal of Gastrointestinal Surgery 2023年第3期15卷 346-361页

作者： Yue-Cui Li Wei-Yue Hu cheng-hang Li Li-Li Zhang Xiang-Wei Xu Jin Li Hong-Xia Luo Department of Infectious Diseases The First People’s Hospital of YongkangJinhua 321300Zhejiang ProvinceChina

BACKGROUND The relationship between hepatitis B surface antigen(HBsAg)-positive carrier status and liver cancer has been extensively ***,the epigenetic changes that occur during progression from HBsAg-positive carrier status or cirrhosis to liver cancer are *** epigenetic modification of DNA hydroxymethylation is critical in tumor ***,5-hydroxymethylcytosine(5hmC)is an important base for DNA demethylation and epigenetic *** is also involved in the assembly of chromosomes and the regulation of gene ***,the mechanism of action of 5hmC in HBsAgpositive carriers or patients with cirrhosis who develop liver cancer has not been fully *** To investigate the possible epigenetic mechanism of HBsAg-positive carriers and hepatocellular carcinoma(HCC)progression from *** Forty HBsAg-positive carriers,forty patients with liver cirrhosis,and forty patients with liver cancer admitted to the First People's Hospital of Yongkang between March 2020 and November 2021 were selected as *** DNA was extracted using a cf-DNA *** was extracted by 5hmC DNA sequencing for principal component analysis,the expression profiles of the three groups of samples were detected,and the differentially expressed genes(DEGs)modified by hydroxymethylation were *** analysis was used to enrich DEGs,such as in biological *** A total of 16455 hydroxymethylated genes were *** results showed that 32 genes had significant 5hmC modification differences between HBsAg carriers and liver cancer patients,of which 30 were upregulated and 2 downregulated in patients with HCC compared with HBsAg-positive *** 5hmC modification differences between liver cirrhosis and liver cancer patients were identified in 20 genes,of which 17 were upregulated and 3 were downregulated in patients with HCC compared with those with *** genes may have potential

关键词： Hepatitis B surface antigen 5-hydroxymethylcytosine Hepatocellular carcinoma Liver cancer DNA sequencing Differentially expressed genes

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Highly crystalline Y3Al5O12:Ce3+ phosphor-in-silica glass ceramics for high-power solid-state lighting

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Journal of Rare Earths 2024年第11期42卷 2051-2057页

作者： Shisheng Lin hang Lin Hongyi Yang Pengfei Wang Ping Sui Ju Xu Yao cheng Yuansheng Wang Key Laboratory of Optoelectronic Materials Chemistry and Physics Fujian Institute of Research on the Structure of MatterChinese Academy of Sciences Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China Xiamen Institute of Rare-earth Materials Haixi InstitutesChinese Academy of Sciences College of Chemistry and Materials Science Fujian Normal University

The pursuit of high-brightness solid-state lighting（SSL） stimulates the development of all-inorganic color converters with high *** is required that the fluorescent material is able to cope with the extreme condition generated from the irradiation of high-power-density excitation *** such,in this work,we developed a new composite color converter,i,e.,Y3Al5O12:Ce3+phosphor-in-silica glass ceramic(YAG:Ce3+PiSGC).Remarkably,the amorphous SiO2matrix spontaneously transforms into tetragonal SiO2crystallites during co-sintering with crystallization fraction reaching up to>90%（almost full ceramization）.The activation energy for crystallization Ecand Avrami index n of amorphous silica oxide are 298.5 kJ/mol and 1.71,indicating the diffusion-controlled glass crystallization *** fabricated prototype high-power phosphor-converted white light-emitting diode（pc-wLED） and phosphor-converted white laser diode（pc-wLD） based on YAG:Ce3+PiSGC show satisfactory photometric/colorimetric *** developed color co nverters have combined merits of environmental protection property,cost-effective manufacturing,good luminescent performance,and easy *** study highlights a new kind of opto-functional composite material and its application as an efficient color converter in high-power solid-state lightings.

关键词： Glass ceramics Laser-driven white light Rare earths White light-emitting diode Y3Al5O12:Ce3+

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In-situ defect passivation assisted three-step printing of efficient and stable formamidine-lead bromide solar cells

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Journal of Energy Chemistry 2024年第9期96卷 396-405页

作者： hang Yang Tao Zhou Haoyu Cai Wenjian Shen Hao Chen Yongjun Liu Juan Zhao Yi-Bing cheng Jie Zhong State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070HubeiChina Foshan Xianhu Laboratory of the Advanced Energy Science and Technology Guangdong Laboratory Foshan 528216GuangdongChina School of Automobile Engineering Wuhan University of TechnologyWuhan 430070HubeiChina

Perovskite solar cells(PSCs)emerge as the most promising photovoltaics(PV)for their high performance and potential convenient cost-effective production routes comparing to the sophomore PV *** printed PSCs with simplified device architecture and fabrication procedures could further enhance the competitive strength of PSC *** this work,we present an in-situ defect passivation(ISDP)assisted full-printing of high performance formamidine-lead bromide(FAPbBr_(3))*** three rapid printing steps are involved for electron transporting layer(ETL),perovskite and carbon to form a complete solar cell on the low-cost fluorine-doped tin oxide(FTO)***-chain polymer monomethyl ether polyethylene glycol is particularly utilized as the ISDP passivator,leading to conformal coating on the rough FTO and defect passivation for both ETL and perovskite during printing.A high efficiency of 10.85%(certified 10.14%)and a high V_(oc)up to 1.57 V are achieved for the printed *** unencapsulated PSCs maintain above 90%of the initial efficiency after continuously heating at 85℃for 1000 h and over 80%of the efficiency after the maximum power point tracking for 3500 *** fully printed semitransparent PSCs with carbon grids(CGs)show average visible light transmittance over 33%and an efficiency of 8.81%.

关键词： Formamidinium lead bromide Fully printed Lowcosts Carbon electrode Semitransparent

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FeNi Prussian blue analogues on highly graphitized carbon nanosheets as efficient glucose sensors

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Rare Metals 2024年第6期43卷 2730-2738页

作者： Jin-hang Xue Qiu-Hong Sun cheng Han Yuan-Dong Yang Shao-Jie Xu Qi-Peng Li Jin-Jie Qian College of Life and Environmental Science Wenzhou UniversityWenzhou 325000China College of Chemistry and Materials Engineering Wenzhou UniversityWenzhou 325000China College of Chemistry and Chemical Engineering Zhaotong UniversityZhaotong 657000China

Meeting the continuous glucose monitoring requirements of individuals necessitates the research and development of sensors with high sensitivity and *** this study,a straightforward strategy was proposed for synthesizing ultra-thin oxygen-rich graphitized carbon nanosheets(denoted as GCS-O).These nanosheets are obtained by calcining a topologically two-dimensional indium-based coordination ***,the growth of FeNi Prussian blue analogue(PBA)on GCS-O effectively introduces active sites and increases the nitrogen content within the carbonaceous *** resulting FeNi-PBA/GCS-O composite exhibits excellent glucose sensing performance with a broad linear range of 1 to 1300μmol·L^(-1).Meanwhile,it also achieves a high sensitivity of 2496μA·mmol^(-1)·L·cm^(-2),a limit of detection of 100nmol·L^(-1)(S/N=3),and commendable long-term *** relatively simple synthesis process,exceptional sensitivity,and satisfactory electrochemical sensing performance of FeNi-PBA/GCS-O open up new directions for biosensor applications.

关键词： Coordination polymer Carbon nanosheet Prussian blue analogue Surface reconstruction Glucose oxidation

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无绝缘轨道电路死区段的计算方法

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铁道学报 2000年第5期22卷 51-54页

作者：赵志程荫杭北方交通大学电子信息工程学院北京100044

通过对 UM71无绝缘轨道电路电气绝缘节分路灵敏度的分析 ,找出不满足标准分路灵敏度的区段 (即死区段 ) ,并计算其长度。

关键词：铁道信号轨道电路自动闭塞计算方法死区段

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改进阈值法的轮胎表面磨损的特征提取

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北京交通大学学报 2007年第2期31卷 57-61页

作者：张超程荫杭北京交通大学电子信息工程学院北京100044

轮胎的实时状态受到行驶环境及车辆自身结构的影响,而这些影响可以通过表面纹理的磨损情况得以表征．本文从图像分析着手研究轮胎磨损．考虑到采用单一图像处理方法,会因自身的适用范围而有所局限,甚至有时得不到相应的结果,提出了改进... 详细信息

轮胎的实时状态受到行驶环境及车辆自身结构的影响,而这些影响可以通过表面纹理的磨损情况得以表征．本文从图像分析着手研究轮胎磨损．考虑到采用单一图像处理方法,会因自身的适用范围而有所局限,甚至有时得不到相应的结果,提出了改进阈值法来提取轮胎磨损纹理特征．该方法包括阈值分割和区域标注两个部分．通过给定初始阈值的迭代优化以及种子填充,图像被分割成具有独立轮廓和结构参数的多单元块．再根据相应的磨损机制进一步分析出磨损原因．实例表明,与Ostu,watershed和主动轮廓线法相比,该方法对不确定的位置有一定的冗余度,分割清晰,速度快,有助于磨损分析．

关键词：轮胎表面磨损改进阈值法特征提取

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Anti-BCMA CAR-T Cell Therapy in Relapsed or Refractory Multiple Myeloma Patients with Impaired Renal Function

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Current Medical Science 2021年第3期41卷 474-481页

作者： Shao-long HE Yu-hang cheng Di WANG Meng-lei XU Yi-mei QUE Yan-jie XU Liang-ming MA Chun-rui LI Jian-feng ZHOU Department of Hematology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Third Hospital of Shanxi Medical University Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalTongji Medical CollegeHuazhong University of Science and TechnologyTaiyuan 030032China

Anti-B cell maturation antigen(BCMA)chimeric antigen receptor(CAR)T-cell therapyis effective and well-tolerated for refractory or relapsed multiple myeloma(RRMM).The purposcof the present study was to analyze efficacy in RRMM patients with renal impairment treated byanti-BCMA CAR-T cell therapy.A total of 59 RRMM patients were selected,and divided intoimpaired renal function(lRF)group[basclinc cstimated giomerular filtration rate(eSFR)<90 m/min/1.73 m^2(n=18)]and normal renal function(NRF)group(baseline eGFR≥90 mL/min/1.73 m,n=41).For patients with IRF,eGFR at the 6th month post-CAR-T cells infusion was significantlyhigher than the baseline(P<0.05).The multivariate analysis showed that light chain type and beta-2 micro-globulin(bcta-2M)were associated factors with the decrease of serum ***-free survival(PFS)in the NRF group and IRF group was 266 days and 181 *** survival(OS)in the NRF group and lRF group was 877 days and 238 *** was no significant difference in the objective response rate(ORR)between thelRF group and the NRF *** is suggested that CAR-T cells therapy could improve the renalfunction during the treatment of *** renal function could be more significantly improvedin RRMM patients with light chain type than with other types.

关键词： relapsed or refractory multiple myeloma chimeric antigen receptor T-cell therapy impaired renal function B cell maturation antigen

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