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Performance study of vertical MSM solar-blind photodetectorsbased onβ-Ga_(2)O_(3)thin film

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The Journal of China Universities of Posts and Telecommunications 2024年第2期31卷 17-27页

作者： Chen Haifeng Che Lujie Lu Qin Wang Shaoqing Liu Xiangtai Liu Zhanhang Guan Youyou Zhao Xu cheng hang Han Xiaocong Zhang Xuhui School of Electronic Engineering Xi'an University of Posts and TelecommunicationsXi'an 710121China

In this work,β-Ga_(2)O_(3)thin films were grown on SiO_(2)substrate by atomic layer deposition(ALD)and annealed in N_(2)atmosphere to enhance the crystallization quality of the thin films,which were verified from X-rays diffraction(XRD).Based on the grownβ-Ga_(2)O_(3)thin films,vertical metal-semiconductor-metal(MSM)interdigital photodetectors(PDs)were fabricated and *** PDs have an ultralow dark current of 1.92 pA,ultra-high photo-to-dark current ratio(PDCR)of 1.7×10^(6),and ultra-high detectivity of 4.25×10^(14)Jones at a bias voltage of 10 V under 254 nm deep ultraviolet(DUV).Compared with the horizontal MSM PDs under the same process,the PDCR and detectivity of the fabricated vertical PDs are increased by 1000 times and 100 times,*** addition,the vertical PDs possess a high responsivity of 34.24 A/W and an external quantum efficiency of 1.67×10^(4)%,and also exhibit robustness and repeatability,which indicate excellent *** the effects of electrode size and external irradiation conditions on the performance of the vertical PDs continued to be investigated.

关键词： Ga_(2)O_(3) atomic layer deposition(ALD) annealing vertical metal-semiconductor-metal(MSM)interdigital photodetectors

Multidisciplinary management of ulcerative colitis complicated by immune checkpoint inhibitor-associated colitis with life-threatening gastrointestinal hemorrhage:A case report

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2329-2336页

作者： Na Hong Bo Wang hang-cheng Zhou Zheng-Xiang Wu Hua-Ying Fang Geng-Qing Song Yue Yu Department of Gastroenterology The First Affiliated Hospital of University of Science and Technology of ChinaDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Pathology The First Affiliated Hospital of University of Science and Technology of ChinaDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230036Anhui ProvinceChina Intelligent Pathology Institute Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230036Anhui ProvinceChina Department of Gastroenterology and Hepatology Metro Health Medical CenterCase Western Reserve UniversityClevelandOH 44109United States

BACKGROUND Programmed cell death 1(PD-1)inhibitors are immune checkpoint inhibitors(ICI)that have demonstrated significant efficacy in treating various advanced malignant *** most patients tolerate treatment well,several adverse drug reactions,such as fatigue,myelosuppression,and ICI-associated colitis,have been *** SUMMARY This case involved a 57-year-old male patient with ulcerative colitis complicated by hepatocarcinoma who underwent treatment with tirelizumab(a PD-1 inhibitor)for six *** treatment led to repeated life-threatening lower gastrointestinal *** patient received infliximab,vedolizumab,and other salvage procedures but ultimately required subtotal colectomy due to uncontrollable massive lower gastrointestinal ***,postoperative gastrointestinal bleeding has stopped,the patient’s stool has turned yellow,and his full blood cell count has returned to *** This case highlights the necessity of early identification,timely and adequate treatment of ICI-related colitis,and rapid escalation to achieve the goal of improving prognosis.

关键词： Ulcerative colitis Hepatocarcinoma Immune checkpoint inhibitor-associated colitis Colectomy Case report

Milk fat globule epidermal growth factor 8 alleviates liver injury in severe acute pancreatitis by restoring autophagy flux and inhibiting ferroptosis in hepatocytes

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World Journal of Gastroenterology 2024年第7期30卷 728-741页

作者： Qing Cui hang-cheng Liu Wu-Ming Liu Feng Ma Yi Lv Jian-Cang Ma Rong-Qian Wu Yi-Fan Ren Department of Cardiology Xi’an Central Hospital Affiliated to Xi’an Jiaotong UniversityXi’an 710003Shaanxi ProvinceChina Department of General Surgery The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710004Shaanxi ProvinceChina National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine Shaanxi Provincial Center for Regenerative Medicine and Surgical EngineeringFirst Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Department of Vascular Surgery The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710004Shaanxi ProvinceChina

BACKGROUND Liver injury is common in severe acute pancreatitis(SAP).Excessive autophagy often leads to an imbalance of homeostasis in hepatocytes,which induces lipid peroxidation and mitochondrial iron deposition and ultimately leads to *** previous study found that milk fat globule epidermal growth factor 8(MFG-E8)alleviates acinar cell damage during SAP via binding toαvβ3/5 ***-E8 also seems to mitigate pancreatic fibrosis via inhibiting chaperone-mediated *** To speculate whether MFG-E8 could also alleviate SAP induced liver injury by restoring the abnormal autophagy *** SAP was induced in mice by 2 hly intraperitoneal injections of 4.0 g/kg L-arginine or 7 hly injections of 50μg/kg cerulein plus ***8-knockout mice were used to study the effect of MFG-E8 deficiency on SAPinduced liver ***,a specificαvβ3/5 integrin inhibitor,was used to investigate the possible mechanism of *** The results showed that MFG-E8 deficiency aggravated SAP-induced liver injury in mice,enhanced autophagy flux in hepatocyte,and worsened the degree of *** MFG-E8 reduced SAP-induced liver injury in a dose-dependent ***,MFG-E8 mitigated excessive autophagy and inhibited ferroptosis in liver *** abolished MFG-E8’s beneficial effects in SAP-induced liver *** MFG-E8 acts as an endogenous protective mediator in SAP-induced liver ***-E8 alleviates the excessive autophagy and inhibits ferroptosis in hepatocytes by binding to integrinαVβ3/5.

关键词： Autophagy flux Ferroptosis Liver injury Milk fat globule epidermal growth factor 8 αvβ3/5 integrins Acute pancreatitis

CrN supported by carbon nanosheets as efficient catalysts toward oxygen reduction reaction and Zn-air batteries

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Rare Metals 2024年第10期43卷 4973-4981页

作者： Ya-Ting Zhang Fan Zhang Zhe Lu Jun-Ming Luo Su-Yang Feng Qi Wang Hui Chen Hao-Ming Wu Zheng-Pei Miao Bin Chi Neng Yu cheng-hang You Jing Li Xin-Long Tian School of Chemistry and Chemical Engineering School of Marine Science and EngineeringHainan Provincial Key Lab of Fine ChemistryHainan University State Power Investment Group Hainan Electric Power Co.Ltd. Key Laboratory of Fuel Cell Technology of Guangdong Province Shenzhen Automotive Research Institute Beijing Institute of Technology State Key Laboratory of Nuclear Resources and Environment East China University of Technology

Exploring non-precious efficient oxygen reduction reaction （ORR） catalysts is of great significance to fuel cells and Zn-air batteries （ZABs）.CrN is a theoretically promising ORR catalyst,but its potential needs to be unlocked by proper supports that provide high conductivity and high exposure of active *** this work,we introduce a novel synthesis of carbon nanosheets-supported CrN nanoparticles （CrN/C） by annealing the mixture of CrCl3,1,10-phenanthroline and melamine via a two-step *** prepared CrN/C materials show good ORR activity and stability in acidic and alkaline *** optimal CrN/C material has an ORR half-wave potential of 0.73 and 0.72 V （*** hydrogen electrode） in acidic and alkaline media,*** it retains 82% and 78% of ORR current density in acidic and alkaline media after durability tests,***,the optimal CrN/C material-based self-breathing ZABs deliver a maximum power density of 168 mW·cm-2,which is one of the highest among transition metal nitrides-based ZABs It is found that the ORR activity of CrN/C materials is highly related to the Cr–N valence *** work highlights the good potential of CrN as robust ORR catalyst and verifies its promising application in ZABs.

关键词： Carbon nanosheets CrN Fuel cells Oxygen reduction reaction Zn-air batteries

High-frequency microwave cavity design for high-mass dark matter axion searches

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Chinese Physics B 2024年第5期33卷 87-94页

作者：张驰王佳李春光陈石广程航孙亮吴云 Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Songshan Lake Materials Laboratory Dongguan 523808China Hefei National Laboratory Hefei 230088China

The haloscope based on the TM_(010)mode cavity is a well-established technique for detecting QCD ***,the method has limitations in detecting high-mass axion due to significant volume loss in the high-frequency *** a higher-order mode cavity can effectively reduce the volume loss of the high-frequency *** rotatable dielectric pieces as a tuning mechanism can compensate for the degradation of the form factor of the higher-order ***,the introduction of dielectric causes additional volume *** address these issues,this paper proposes a novel design scheme by adding a central metal rod to the higher-order mode cavity tuned by dielectrics,which improves the performance of the haloscope due to the increased effective volume of the cavity *** superiority of the novel design is demonstrated by comparing its simulated performance with previous ***,the feasibility of the scheme is verified by the full-wave simulation results of the mechanical design model.

关键词： axion haloscope microwave cavity

Tumour response following preoperative chemotherapy is affected by body mass index in patients with colorectal liver metastases

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 331-342页

作者： Hua-Chuan Song hang-cheng Zhou Ping Gu Bing Bao Quan Sun Tian-Ming Mei Wei Cui Kang Yao Huan-Zhang Yao Shen-Yu Zhang Yong-Shuai Wang Rui-Peng Song Ji-Zhou Wang Department of General Surgery Provincial Hospital Affiliated to Anhui Medical UniversityHefei 230001Anhui ProvinceChina Department of Hepatobiliary Surgery The First Affiliated Hospital of University of Science and Technology of ChinaDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Pathology The First Affiliated Hospital of University of Science and Technology of ChinaDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Gastrointestinal Surgery Tongcheng People’s HospitalTongcheng 231400Anhui ProvinceChina Department of Gastrointestinal Surgery Suzhou Hospital Affiliated to Anhui Medical UniversitySuzhou 234000Anhui ProvinceChina Department of General Surgery Xuancheng People’s HospitalXuancheng 242000Anhui ProvinceChina

BACKGROUND Colorectal cancer is the third most prevalent malignancy globally and ranks second in cancer-related mortality,with the liver being the primary organ of *** chemotherapy is widely recommended for initially or potentially resectable colorectal liver metastases(CRLMs).Tumour pathological response serves as the most important and intuitive indicator for assessing the efficacy of ***,the postoperative pathological results reveal that a considerable number of patients exhibit a poor response to preoperative *** mass index(BMI)is one of the factors affecting the tumori-genesis and progression of colorectal cancer as well as prognosis after various antitumour *** studies have indicated that overweight and obese patients with metastatic colorectal cancer experience worse prognoses than those with normal weight,particularly when receiving first-line chemotherapy regimens in combination with *** To explore the predictive value of BMI regarding the pathologic response following preoperative chemotherapy for *** A retrospective analysis was performed in 126 consecutive patients with CRLM who underwent hepatectomy following preoperative chemotherapy at four different hospitals from October 2019 to July *** and multivariate logistic regression models were applied to analyse potential predictors of tumour pathological *** Kaplan-Meier method with log rank test was used to compare progression-free survival(PFS)between patients with high and low ***<24.0 kg/m^(2) was defined as low BMI,and tumour regression grade 1-2 was defined as complete tumour *** Low BMI was observed in 74(58.7%)patients and complete tumour response was found in 27(21.4%)*** rate of complete tumour response was significantly higher in patients with low BMI(29.7%vs 9.6%,P=0.007).Multivariate analysis revealed that low BMI[odds ratio(OR)=4.56,95%confidence interval(CI):1

关键词： Colorectal liver metastases Body mass index Tumour regression grade Preoperative chemotherapy Hepatectomy

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英汉是非问句应答机制的句法–语用研究

外语教学与研究 2024年第1期56卷 39-51,159页

作者：程航张庆文广东外语外贸大学外国语言学及应用语言学研究中心广东省广州市510420

本文从句法-语用界面探究不同语境下英汉是非问句的不同应答方式,尝试从命题极性和命题交互两个角度来阐释不同应答方式间的差异,并提出相应的结构分析。研究发现,应答是非问句时,英语yes和汉语重复动词用于回答命题极性,汉语“是”用... 详细信息

本文从句法-语用界面探究不同语境下英汉是非问句的不同应答方式,尝试从命题极性和命题交互两个角度来阐释不同应答方式间的差异,并提出相应的结构分析。研究发现,应答是非问句时,英语yes和汉语重复动词用于回答命题极性,汉语“是”用于回应问话人偏向。回答命题极性时,应答标记对疑问作出回答,关联命题极性;回应问话人偏向时,应答标记反映问话人偏向命题与应答者背景知识中命题的重合性,体现命题交互关系。根据不同应答方式在应答对象方面的差异,本文将应答细分为“回答”和“回应”,结构上分别对应“回答结构”和“回应结构”,并将此分析拓展至对英汉其他句类应答的结构分析。

关键词：是非问句应答标记偏向性命题交互

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匹配变换和线性变换融合的水下图像增强

实验室研究与探索 2024年第7期43卷 23-27,182页

作者：段燕北程航南昌工学院实验实训中心南昌330108 南昌工学院教务处南昌330108

为了有效地改善水下图像的颜色和对比度,提出了匹配变换和线性变换融合的水下图像增强方法。对强度最大的通道图像进行对比度限制的自适应直方图均衡化,根据均衡化后的通道图像直方图,对另外两通道图像分别进行直方图匹配,最后得到颜色... 详细信息

为了有效地改善水下图像的颜色和对比度,提出了匹配变换和线性变换融合的水下图像增强方法。对强度最大的通道图像进行对比度限制的自适应直方图均衡化,根据均衡化后的通道图像直方图,对另外两通道图像分别进行直方图匹配,最后得到颜色校正的图像。在HSV颜色空间中,对颜色校正图像的明度分量进行自适应分段线性变换,得到对比度增强的图像。分别计算2张增强图像的对比度权重、显著性权重、亮度分布权重和饱和度权重,根据权重对2张增强图像进行多尺度金字塔加权融合,得到最后的增强图像。实验结果表明,该方法对水下图像增强后的视觉效果优于现有方法,对应的平均梯度、水下彩色图像质量评价(UCIQE)指标和水下图像质量(UIQM)指标比现有方法分别提高30.0%、7.29%和16.0%。

关键词：水下图像增强直方图匹配自适应分段线性变换金字塔加权融合

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财产权的张力:洛克与马克思

学习与探索 2024年第8期 27-35,180页

作者：白刚程远航吉林大学哲学基础理论研究中心吉林大学哲学社会学院

洛克作为近代政治哲学财产权思想的开创者,在《政府论》中从自然权利论说出发,提出“劳动创造价值”的劳动所有权思想。马克思继承了洛克劳动所有权思想的核心,在劳动价值论的基础上发现剩余价值,揭露资本家对劳动者剩余价值的无偿占有... 详细信息

洛克作为近代政治哲学财产权思想的开创者,在《政府论》中从自然权利论说出发,提出“劳动创造价值”的劳动所有权思想。马克思继承了洛克劳动所有权思想的核心,在劳动价值论的基础上发现剩余价值,揭露资本家对劳动者剩余价值的无偿占有,开启了财产权的资本逻辑批判。在《资本论》中,马克思发现资本主义财产权是以劳动所有权为外在形式,背后隐匿着否定自我所有的资本所有权,揭示了财产权的现代分离。马克思将洛克的劳动所有权发展为劳动力所有权,在重建个人所有制中实现人的自我所有,完成了对财产权的正义建构。

关键词：财产权劳动所有权劳动价值论资本所有权劳动力所有权

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