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Oceanic environmental changes of subarctic Bering Sea in recent 100 years: Evidence from molecular fossils

Science China Earth Sciences 2005年第4期48卷 555-564页

作者： LU Bing chen Ronghua ZHOU Huaiyang WANG Zipan chen jianfang ZHU Chun Key Laboratory of State Oceanic Administration The Second Institute of Oceanography Hangzhou 310012 China Key Laboratory of State Oceanic Administration The Second Institute of Oceanography Hangzhou 310012 China Key Laboratory of State Oceanic Administration The Second Institute of Oceanography Hangzhou 310012 China Key Laboratory of State Oceanic Administration The Second Institute of Oceanography Hangzhou 310012 China Key Laboratory of State Oceanic Administration The Second Institute of Oceanography Hangzhou 310012 China Key Laboratory of State Oceanic Administration The Second Institute of Oceanography Hangzhou 310012 China

The core sample B2-9 from the seafloor of the subarctic Bering Sea was dated with 210 Pb to obtain a consecutive sequence of oceanic sedimentary environments at an interval of a decade during 1890—1999. A variety of molecular fossils were detected, including n-alkanes, isoprenoids, fatty acids, sterols, etc. By the characteristics of these fine molecules (C27, C28, and C29 sterols) and their molecular indices (Pr/Ph, ∑C+22/∑C?21, CPI and C18∶2/C18∶0) and in con- sideration of the variation of organic carbon content, the 100-year evolution history of subarctic sea paleoenvironment was reestablished. It is indicated that during the past 100 years in the Arctic, there were two events of strong climate warming (1920—1950 and 1980—1999), which resulted in an oxidated sediment environment owing to decreasing terrigenous organic matters and increasing marine-derived organic matters, and two events of transitory climate cooling (1910 and 1970—1980), which resulted in a slightly reduced sediment environment owing to increasing terrigenous organic matters and decreasing marine-derived organic matters. It is re- vealed that the processes of warming/cooling alternated climate are directly related to the Arctic and global climate variations.

关键词： subarctic, molecular fossil, paleoenvironment, record of stratigraphy.

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Paleoceanographic records in the Chukchi Basin, western Arctic Ocean during the late Quaternary

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Acta Oceanologica Sinica 2012年第1期31卷 83-94页

作者： WANG Rujian XIAO Wenshen SHAO Lei chen jianfang GAO Aiguo State Key Laboratory of Marine Geology Tongji UniversityShanghai 200092China Second Institute of Oceanography State Oceanic AdministrationHangzhou 310012China Department of Oceanography Xiamen UniversityXiamen 361005China

The late Quaternary paleoceanographic changes in the western Arctic Ocean are revealed by quan- titative studies of foraminiferal abundance, ice-rafted detritus （IRD） and its mineralogical and petrological compositions, planktonic Neogloboquadrina pachyderma （sin.）（Nps）-δ18O and -δ13C, biogenic and non-biogenic components in Core M03 token from the Chukchi Basin during the Sec- ond Chinese National Arctic Expedition cruise. Seven IRD events appeared at MIS 7, 5, 3 and 1. These IRD were carried in massive icebergs, which were exported to the Beaufort Sea through the M＇Clure Strait Ice Stream, Canadian Arctic Archipelago, and then transported into the Chukchi Basin by the Beaufort Gyre. Low IRD deposition occurred during the glacial times when more extended ice cover and weakened Beaufort Gyre, while the open water condition and the intensified Beaufort Gyre during interglacial periods favored the IRD deposition. Therefore, the IRD events not only indicate the provenance of coarser detritus and ice export events, but also reflect the evolutionary histories of the Beaufort Gyre and North American ice sheet. Seven light Nps-δ18O and -δ13C excursions could respond to enhanced rates of sea ice formation resulting in the pro- duction and sinking of isotopically light brines, but was irrelevant to the warm Atlantic water and freshwater inputs. Whereas, the heavy Nps-δ18O and -δ13C values separately reflect the lessened Arctic freshwater and Pacific water, and well-ventilated surface water from the continental shelf and halocline water. Variations of CaCO3 content and planktonic foraminiferal abundance during the interglacial and glacial periods can demonstrate the incremental or diminishing input of the Atlantic water, while the total organic carbon （TOC） and opal contents increased and decreased during the glacial and interglacial periods, respectively, which could be related to the TOC degradation, opal dissolution and redox conditions of interface between the bottom wat

关键词： IRD events ice sheet light Nps-δ18O and -δ13C excursions surface productivity late Quaternary Arctic Ocean Chukchi Basin

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银耳多糖的抗氧化活性及对成纤维细胞蛋白基因表达的影响

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现代食品科技 2024年第7期40卷 64-71页

作者：陈建芳刘思思张彤赫黄利朱小花黄儒强华南师范大学生命科学学院广东广州510631 河南省食品和盐业检验技术研究院河南郑州450003 广东省海洋生物废弃物综合利用重点实验室广东湛江524552

银耳多糖是银耳中的主要活性物质,具有抗氧化、抗衰老等多种功效。环境中广泛存在的化学污染物苯并[a]芘(Benzo[A]Pyrene, BaP)可通过皮肤吸收代谢,产生致癌性风险。实验通过体外测定银耳粗多糖抗氧化活性,再通过细胞实验测定BaP与银耳... 详细信息

银耳多糖是银耳中的主要活性物质,具有抗氧化、抗衰老等多种功效。环境中广泛存在的化学污染物苯并[a]芘(Benzo[A]Pyrene, BaP)可通过皮肤吸收代谢,产生致癌性风险。实验通过体外测定银耳粗多糖抗氧化活性,再通过细胞实验测定BaP与银耳多糖共同作用下成纤维细胞中胶原蛋白(Collagen Ⅰ、Collagen Ⅲ)、弹性蛋白(Elastin)和间质胶原酶(Matrix Metalloproteinases-1,MMP-1)的mRNA表达量的变化,及Collagen Ⅰ的蛋白质含量,测定多糖的抗衰老作用。研究发现,银耳多糖有较好的体外抗氧化活性,超氧阴离子自由基清除率最高为70.28%,DPPH自由基清除率为50.10%,羟基自由基清除率为32.69%。仅0.1μg/mL银耳多糖能有效抑制20μmol/L BaP对相关基因表达的刺激(P<0.05)。其中Collagen Ⅰ、Collagen Ⅲ和Elastin基因表达量呈现多糖浓度依赖性增加。在BaP暴露下,尽管胶原蛋白基因表达量增大至1.26倍,但是大量表达的MMP-1降解了胶原蛋白,因此银耳多糖作用下Collagen-1的含量减少至3.06μg/L(低于空白对照组3.48μg/L)。说明银耳多糖能有效抑制化BaP对细胞的伤害,并促进细胞基因的表达,其中浓度具重要影响。

关键词：银耳多糖苯并[a]芘 Ⅰ型胶原蛋白间质胶原酶 Ⅲ型胶原蛋白弹性蛋白

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防己黄芪汤联合穴位埋线治疗脾虚痰湿型单纯性肥胖的回顾性队列研究

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中医药信息 2024年第4期41卷 55-60页

作者：姜健胡春平陈见纺严军上海市嘉定区中医医院/上海中医药大学教学医院上海201800

目的:观察防己黄芪汤联合穴位埋线治疗脾虚痰湿型单纯性肥胖的疗效与安全性。方法:采用回顾性队列研究方法,选取上海市嘉定区中医医院代谢与肥胖专病门诊收治的单纯性肥胖患者,最终纳入统计分析共175例,其中治疗组95例,对照组80例。治... 详细信息

目的:观察防己黄芪汤联合穴位埋线治疗脾虚痰湿型单纯性肥胖的疗效与安全性。方法:采用回顾性队列研究方法,选取上海市嘉定区中医医院代谢与肥胖专病门诊收治的单纯性肥胖患者,最终纳入统计分析共175例,其中治疗组95例,对照组80例。治疗组予以防己黄芪汤联合穴位埋线治疗,对照组予以二甲双胍缓释片治疗,疗程3个月,观察患者体质量、腰围、BMI、减重结局、中医证候疗效等主要指标;胰岛素抵抗指数(HOMA-IR)、糖化血红蛋白(HbA1c)和血脂等次要指标;肝肾功能等安全性指标。结果:与对照组比较,治疗组患者随时间的延长,体质量、BMI、腰围明显下降,达到临床减重结局的发生率明显更高,且治疗组HOMA-IR、HbA1c、甘油三酯等指标明显改善(P<0.05)。中医证候疗效方面,治疗组总有效率89.47%(85/95),优于对照组51.25%(41/80),差异具有统计学意义(P<0.05)。治疗过程中两组患者均未见肝肾功能异常。结论:防己黄芪汤联合穴位埋线可明显减轻患者体质量,改善血糖和胰岛素抵抗以及脂代谢,患者依从性良好,具有较好的安全性。

关键词：单纯性肥胖脾虚痰湿型防己黄芪汤穴位埋线队列研究

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Bio-Organic Geochemistry research in China: Advances,opportunities and challenges

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Science China Earth Sciences 2018年第12期61卷 1775-1780页

作者： Chuanlun ZHANG Ping'an PENG Meixun ZHAO Shucheng XIE jianfang chen Weiguo LIU Shenzhen Key Laboratory of Marine Archaea Geo-Omics Department of Ocean Science and EngineeringSouthern University of Science and Technology Laboratory for Marine Geology Qingdao National Laboratory for Marine Science and Technology State Key Laboratory of Organic Geochemistry Guangzhou Institute of Geochemistry Chinese Academy of Sciences Key Laboratory of Marine Chemistry Theory and Technology (Ocean University of China) Ministry of Education/Laboratory for Marine Ecology and Environmental Science Qingdao National Laboratory for Marine Science and Technology State Key Laboratory of Biogeology and Environmental Geology School of Earth Sciences China University of Geosciences Key Laboratory of Marine Ecosystem and Biogeochemistry State Oceanic Administration State Key Laboratory of Loess and Quaternary Geology Institute of Earth EnvironmentChinese Academy of Sciences

The discipline of "Bio-Organic Geochemistry" is a cross research field between biogeochemistry and traditional organic geochemistry, which focuses on geochemical processes related to the biosynthesis of organic molecules(particularly lipids) by(micro) organisms, organic matter production by primary producers, degradation of organic matter by microbial processes recorded by retainable lipid biomarkers, and organic proxies for studies of paleo-climate, paleo-environments, paleoecology and Earth evolution. This field aims to go beyond the traditional petroleum-oriented Organic Geochemistry by integrating with biogeochemical concepts concerned mostly with biomolecules from cellular material such as DNA and lipids. A formal Chinese organization in Bio-Organic Geochemistry was established in 2012 when the first conference was held in Guangzhou. This organization has witnessed rapid growth over the past six years with focused research addressing organic proxies in paleoclimate and paleoenvironmental applications, with particular rapid development in glycerol dialkyl glycerol tetraethers-derived proxies. Most progresses in China so far are made following or paralleling the international trend in biogeochemical studies. Things have begun to change with China's ambitious initiatives in several bio-geo programs such as the Ocean Deep Drilling Program of China, the Microbial Hydrosphere Program, the Deep Carbon Observatory, and the Microbiome Program. Looking forward in the 21 st Century, the growing Chinese research community in Bio-Organic Geochemistry faces grand opportunities and challenges as Chinese scientists propel themselves toward global research frontiers.

关键词： Bio-Organic Geochemistry Biogeochemistry Geomicrobiology Paleoclimate proxies Carbon cycles Microbial genomics

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基于融合式教学的“医学免疫学”课程改革探索与实践

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微生物学通报 2024年第4期51卷 1190-1208页

作者：梅建军王艳芳陈建芳张涛刘友刘晓梅任可包头医学院基础医学与法医学院内蒙古包头014040

建设高质量课程、培养高层次医学人才是我国高等医学教育发展的重要环节。融合式教学是利用各种教学技术、方法和资源,将相关教学要素、环节优化组合,实现融合增效的教学效果,在高质量课程建设和高层次医学人才培养方面有着重要的理论... 详细信息

建设高质量课程、培养高层次医学人才是我国高等医学教育发展的重要环节。融合式教学是利用各种教学技术、方法和资源,将相关教学要素、环节优化组合,实现融合增效的教学效果,在高质量课程建设和高层次医学人才培养方面有着重要的理论研究和实践应用价值。我校“医学免疫学”课程教学团队围绕跨学科融合、专业知识与思政元素融合、研究新成果与团队成员科研成果融合等方面组建教学内容,建设教学资源,体现了医学免疫学与微生物学的高度融合。开展跨学科融合教学、课程思政教学、信息化教学及实践创新融合教学,学生的学业水平、专业素养和创新能力得到明显提升。课程改革的成果和经验可为其他医学课程的融合式教学改革思路提供参考意义,促进医学课程建设高质量发展。

关键词：融合式教学医学免疫学课程建设

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Ice rafting history and paleoceanographic reconstructions of Core 08P23 from southern Chukchi Plateau, western Arctic Ocean since Marine Isotope Stage 3

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Acta Oceanologica Sinica 2015年第3期34卷 68-75页

作者： ZHANG Taoliang WANG Rujian XIAO Wenshen chen Zhihua chen jianfang chenG Zhenbo SUN Yechen State Key Laboratory of Marine Geology Tongji University The First Institute of Oceanography State Oceanic Adiministration The Second Institute of Oceanography State Oceanic Adiministration

Multiproxy investigations have been performed on Core 08P23 collected from the Chukchi Plateau, the western Arctic Ocean, during the Third Chinese National Arctic Expedition. The core was dated back to Ma-rine Isotope Stage （MIS） 3 by a combination of Accelerator Mass Spectrometric （AMS） carbon-14 dating and regional core correlation. A total of five prominent ice-rafted detritus （IRD） events were recognized in MIS 2 and MIS 3. The IRD sources in MIS 3 are originated from vast carbonate rock outcrops of the Canadian Arctic Archipelago and clastic quartz in MIS 2 may have a Eurasian origin. Mostδ18O andδ13C values of Neogloboquadrina pachyderma （sinistral）（Nps） in Core 08P23 are lighter than the average values of surface sediments. The lighterδ18O andδ13C values of Nps in the two brown layers in MIS 1 and MIS 3 were resulted from meltwater events; and those in the gray layers in MIS 3 were caused by the enhanced sea ice formation. Theδ18O values varied inversely withδ13C in MIS 2 indicate that the study area was covered by thick sea ice or ice sheet with low temperature and little meltwater, which prevented the biological productivity and sea-atmosphere exchange, as well as water mass ventilation. The covaried light values ofδ18O andδ13C in MIS 1 and MIS 3 were resulted from meltwater and/or brine injection.

关键词： Chukchi Plateau western Arctic Ocean Marine Isotope Stage 3 ice rafted detritus events oxygen and carbon isotope water mass changes

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Inorganic Carbon Parameters Responding to Summer Hypoxia Outside the Changjiang Estuary and the Related Implications

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Journal of Ocean University of China 2013年第4期12卷 568-576页

作者： WANG Bin chen jianfang JIN Haiyan LI Hongliang XU Jie Laboratory of Marine Ecosystem and Biogeochemistry Second Institute of Oceanography SOA State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of Oceanography SOA State Key Laboratory of Tropical Marine Environmental Dynamics South China Sea Institute of OceanologyChinese Academy of Sciences

The eutrophication, hypoxia and coastal acidification are attracting more and more attention. In this study, inorganic carbon parameters, including dissolved inorganic carbon （DIC）, total alkalinity （TA） and calculated partial pressure of CO2 （pCO2）, obtained from a summer cruise in August, 2009, were used to investigate their integrated response to biological processes accompanying the oxygen depletion in the areas off the Changjiang Estuary. According to the observations, the typical hypoxia occurred in the bottom water just outside the Changjiang Estuary with Dissolved Oxygen （DO） lower than 2.00 mg L^-1. The biological uptake in the surface water and the decomposition of organic matter in the bottom water were fully coupled with each other. The high concentration of Chl_a （Chl_a = 10.9μgL^-1） and DO （9.25 mgL^-1）, profoundly decreased DIC concentration 0828 μmolkg^-1） and elevated pH （8.42） was observed in the surface water. The correspondingly increased DIC and depletion of oxygen were observed in the bottom water. The semi-quantitative analysis proved that the locally-produced phytoplankton, determined by primary productivity, was deposited to the bottom and contributed about 76% of total amount of the organic carbon decomposition in the bottom. However, in the bottom hypoxia （DO = 2.05 mgL^-1） area observed in the Southern Zhejiang coastal water, the responding patterns of inorganic carbon parameters deviated from the previous one. The expanding of Changjiang Diluted Water （CDW）, the adding of Hangzhou Bay water （with high DIC concentration） and Coastal Current together modify the DIC background value in this area, and the local degeneration and upwelling process may also help to offset the local DIC removed by net biological uptake in surface water. In addition when the mixing occurring in autumn, which may break the summer stratification, the excess release of high DIC in the bottom water to the subsurface water could have an important influence on coastal

关键词： dissolved inorganic carbon (DIC) biological uptake hypoxia coastal acidification

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Variations in organic carbon loading of surface sediments from the shelf to the slope of the Chukchi Sea,Arctic Ocean

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Acta Oceanologica Sinica 2017年第8期36卷 131-136页

作者： LI Zhongqiao WANG Xinyi JIN Haiyan JI Zhongqiang BAI Youcheng chen jianfang Laboratory of Marine Ecosystem and Biogeochemistry Second Institute of OceanographyState Oceanic AdministrationHangzhou 310012China Laboratory of Marine Chemistry and Environment Ocean CollegeZhejiang UniversityZhoushan 316021China State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyState Oceanic AdministrationHangzhou 310012China

The content of organic carbon （OC） normalized to the specific surface area （SSA） of sediment is widely used to trace variations in OC loading （OC/SSA）. This study presents observations of OC/SSA of surface sediments collected in the Chukchi Sea, a typical Arctic marginal sea. Shelf sediments exhibit much higher OC/SSA values than slope sediments in the study area. Compared with OC/SSA values reported from the East Siberian Shelf and Mackenzie River, the slope sediments possess lower OC loading. This abrupt decrease in OC/SSA is mostly related to the lower primary production on slope as well as possible oxidization processes. The results of linear regression analysis between OC and SSA indicate a sedimentary source rock for the OC in the Chukchi Sea sediments. Moreover, shelf sediments with low SSA possess a larger rock OC fraction than slope sediments do. The dataset of the present study enables a more thorough understanding of regional OC cycling in the Chukchi Sea.

关键词： Chukchi Sea Arctic surface sediments organic carbon loading carbon cycle

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近岸海域溶解有机质与金属离子的配位机制及溶解氧的影响特性

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海洋科学 2024年第7期48卷 57-67页

作者：徐啸章天晏夏功伟李宏亮陈建芳郑豪浙江大学海洋学院海洋化学与环境研究所浙江舟山316021 自然资源部第二海洋研究所海洋生态系统与动力学重点实验室浙江杭州310012

溶解有机质(DOM)能与金属离子配位,从而影响金属离子的毒性、迁移转化以及生物可利用性,对近岸养殖区的生态环境产生深远的影响。本文利用三维荧光光谱结合平行因子法研究了舟山近岸海域DOM的组成,采用荧光猝灭滴定并运用修正Stern-Vol... 详细信息

溶解有机质(DOM)能与金属离子配位,从而影响金属离子的毒性、迁移转化以及生物可利用性,对近岸养殖区的生态环境产生深远的影响。本文利用三维荧光光谱结合平行因子法研究了舟山近岸海域DOM的组成,采用荧光猝灭滴定并运用修正Stern-Volmer模型系统研究了DOM各荧光组分与典型的过渡金属离子Cu^(2+)、Fe^(3+)和Pb^(2+)的配位机制,并进一步研究了海水溶解氧对DOM与Cu^(2+)、Fe^(3+)和Pb^(2+)配位作用的影响。结果表明:舟山近岸海域DOM的4种荧光组分,两种类腐殖质组分(C1、C2)明显比2种类蛋白质组分(C3、C4)更易与金属离子配位;DOM与金属离子配位化合物稳定性大小依次是:Cu-DOM>Fe-DOM>Pb-DOM;此外,缺氧环境明显抑制了溶解有机质与Fe^(3+)的配位能力,但Cu^(2+)、Pb^(2+)的配位能力则几乎不受溶解氧浓度的影响。这些结果将为海水养殖水体的调控、恢复提供科学依据。

关键词：海洋溶解有机质金属离子溶解氧配位

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