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SYNERGISTIC EFFECTS OF NOVOLAC-BASED CHAR FORMER WITH A PHOSPHORUS/NITROGEN-CONTAINING FLAME RETARD ANT IN POLYAMIDE 6

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Chinese Journal of Polymer Science 2012年第1期30卷 72-81页

作者： Wei-cheng Xiong Li chen De-yi Wang fei Song Yu-zhong Wang Center for Degradation an-d Flame--Retardant Polymeric Materials College of-Chemistry State Key Laboratory of Polymer Materials Engineering National Engineering Laboratory of Eco-Friendly Polymeric Materials （Sichuan） Sichuan University Chengdu 610064 China

The synergistic effect of phosphorus oxynitride（PON） with a novolac-based char former modified by salification （NA-metal salt） on the flame retardance of polyamide 6（PA6） was *** this purpose,various flame-retardant PA6 systems were melt-compounded with PON,PON/NA,PON/NA-V_2O_5 and PON/NA-Fe_2O_3,and their flame retardance was evaluated by measuring the limiting oxygen index（LOI） values and UL-94 vertical burning *** results showed that,compared with the PA6/PON/NA system,the combination of two char formers（NA-V_2O_5,NA-Fe_2O_3） with PON could obviously improve the char formation and flame retardance of *** flame retardance and cone calorimetric analyses showed the stronger synergism as well as the better flame retardant performance of PON/NA-Fe_2O_3 flame retardant system. The effects of different char formers on the flame retardance and thermal stability of this system were also discussed.

关键词： Polyamide Flame retardance Novolac resin Synergistic effect

Altered Expression of COMP,Collagen 1,and MMP9 in Pelvic Organ Prolapse

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Biomedical and Environmental Sciences 2023年第10期36卷 979-982页

作者： chen yi fei XU Hai Nan DUAN yi Nan XIA Zhi Jun Department of Obstetrics and Gynecology Shengjing Hospital of China Medical UniversityShenyang 110004LiaoningChina Department of Obstetrics and Gynecology Liaoning Province Hospital for Women and ChildrenShenyang 110004LiaoningChina Department of Gynecology Obstetrics and Gynecology Hospital of Fudan UniversityShanghai 200090China

Female pelvic organ prolapse(POP)is a common disorder that affects the quality of life of women *** in China have reported a 9.6%prevalence of symptomatic POP in adult women[1],with a higher prevalence among older women.

关键词： Collagen MMP9 COMP POP

Pre-pregnant Overweight Interacts with ADIPOQ Genetic Variants to Influence Polyunsaturated Fatty Acids in Human Milk

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Biomedical and Environmental Sciences 2023年第7期36卷 635-638页

作者： chen yi Ru LI Yue Ting chen yi fei GONG Jia Yu YANG Jing Yu YU Hai Tao XU Wen Hui PIAO Chun Ji XIE Lin Department of Nutrition and Food Hygiene School of Public HealthJilin UniversityChangchun 130021JinlinChina Experimental Teaching Center for Radiation Medicine School of Public HealthJilin UniversityChangchun 130021JinlinChina

Adiponectin,a specific hormone protein secreted by adipocytes,is a protective factor in the human body and has attracted great attention due to its anti-obesity activity[1,2].The adiponectin gene(ADIPOQ),which is located on human chromosome 3q27,is a single-copy *** single-nucleotide polymorphisms(SNPs)of the human ADIPOQ play an important role in energy balance and are associated with body mass index(BMI)and obesity[3,4].Longchain polyunsaturated fatty acids(LC-PUFAs)have been identified to exert an important role during the first 1,000 days of life on infant growth,neurodevelopment,and visual *** acids,such asα-linoleic acid(ALA,C18:3n-3)and linoleic acid(LA,C18:2n-6),which cannot be synthesized de novo from other lipids,are necessary for biological *** fatty acids such as docosahexaenoic acid(DHA,C22:6n-3)and eicosapentaenoic acid(EPA,C20:5n-3)can be synthesized in neonates from their precursors(LA and ALA).Because of the very low conversion rates in the neonatal liver,it is crucial to provide adequate LC-PUFAs in the diet from early infancy.

关键词： unsaturated weight nates

Effect of Huanglian Jiedu decoction on cogni⁃tive dysfunction of zebrafish with Alzheimer disease

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中国药理学与毒理学杂志 2021年第9期35卷 655-656页

作者： HUANG Yao LIU Kai-fei GUAN Guo-kai chen yi-fei Guilin Medical University Guilin 541199China

OBJECTIVE To investigate the effects of Huanglian Jiedu decoction on cognitive dysfunction of zebrafish with Alzheimer *** 126 g of coptis chinensis,84 g of phellorescent phellorescent chinensis,84 g of scutellaria chinensis and 126 g of gardenia chinensis were immersed in 10,8 and 8 times of water for 30 min,and then extracted at 100℃for 2,1.5 and 1.5 h,*** three extracts were coarse filtered and concentrated into 308 g·L-1 and stored in refrigerator for later use.200 zebrafish were selected for behavioral train⁃ing in T-shaped tank for seven *** that,the behavioral record analysis software Smart 3.0 was used to conduct behavioral *** zebrafish were selected as the blank *** for the blank group,zebrafish in the other 5 groups were exposed to AlCl3100μg·L-1 aquaculture water for modeling,and exposed for 6 *** behavioral record analysis software Smart 3.0 was used to conduct behavioral analysis,and Select the successfully modeled zebraf⁃*** that,huperzine A(4μg·L-1)and Huan⁃glian Jiedu decoction of low,medium and high doses(154,308 and 616 mg·L-1)were adminis⁃tered respectively,and exposed for six ***,the behavior analysis was conducted again through the behavioral record analysis soft⁃ware Smart 3.0 to select qualified *** the training,the brain and gut of zebrafish in each group were collected,and the expression changes of N-cadherin,p-P38/p38MAPK and p-Tau in the brain were detected by Western blot⁃ting and qPCR to show the effect of Huanglian Jiedu decoction on cognitive dysfunction of Zebrafish with Alzheimer *** Western blotting and qPCR results showed that the contents of N-cadherin increased(P<0.05),and the contents of p-P38/p38MAPK and p-Tau decreased(P<0.05)compared with the model group,indicating that Huanglian Jiadu decoction had an effect on the cognitive dysfunction of zebrafish with Alzheimer ***⁃SION Huanglian Jiedu decoction can alleviate cognitiv

关键词： Huanglian Jiedu decoction Alzheimer disease zebrafish cognitive dysfunction

Polysaccharide of Alocasia cucullata Exerts Antitumor Effect by Regulating Bcl-2, Caspase-3 and ERK1/2 Expressions during Long-Time Administration

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Chinese Journal of Integrative Medicine 2024年第1期30卷 52-61页

作者： ZHOU Qi-chun XIAO Shi-lin LIN Ru-kun LI Chan chen Zhi-jie chen yi-fei LUO Chao-hua MO Zhi-xian LIN ying-bo School of Traditional Chinese Medicine Southern Medical UniversityGuangzhou(510515)China Clinical and Basic Research Team of TCM Prevention and Treatment of Non-Small Cell Lung Cancer the Second Clinical College of Guangzhou University of Chinese MedicineGuangzhou(510120)China Department of Chinese Medicine Zhujiang Hospital Affiliated to Southern Medical UniversityGuangzhou(510282)China Department of Pharmacy Jiangmen Central HospitalJiangmen(529000)China

Objective: To study the in vitro and in vivo antitumor effects of the polysaccharide of Alocasia cucullata(PAC) and the underlying mechanism. Methods: B16F10 and 4T1 cells were cultured with PAC of 40 μg/m L, and PAC was withdrawn after 40 days of administration. The cell viability was detected by cell counting kit-8. The expression of Bcl-2 and Caspase-3 proteins were detected by Western blot and the expressions of ERK1/2 mRNA were detected by quantitative real-time polymerase chain reaction(qRT-PCR). A mouse melanoma model was established to study the effect of PAC during long-time administration. Mice were divided into 3 treatment groups: control group treated with normal saline, positive control group(LNT group) treated with lentinan at 100 mg/(kg·d), and PAC group treated with PAC at 120 mg/(kg·d). The pathological changes of tumor tissues were observed by hematoxylin-eosin staining. The cell apoptosis of tumor tissues was detected by TUNEL staining. Bcl-2 and Caspase-3 protein expressions were detected by immunohistochemistry, and the expressions of ERK1/2, JNK1 and p38 mRNA were detected by qRT-PCR. Results: In vitro, no strong inhibitory effects of PAC were found in various tumor cells after 48 or 72 h of administration. Interestingly however, after 40 days of cultivation under PAC, an inhibitory effect on B16F10 cells was found. Correspondingly, the long-time administration of PAC led to downregulation of Bcl-2 protein(P <0.05), up-regulation of Caspase-3 protein(P<0.05) and ERK1 mRNA(P<0.05) in B16F10 cells. The above results were verified by in vivo experiments. In addition, viability of B16F10 cells under long-time administration culture in vitro decreased after drug withdrawal, and similar results were also observed in 4T1 cells. Conclusions: Long-time administration of PAC can significantly inhibit viability and promote apoptosis of tumor cells, and had obvious antitumor effect in tumor-bearing mice.

关键词： polysaccharide of Alocasia cucullata tumor cells Bcl-2 Caspase-3 ERK1/2 Chinese medicine

Effect of rhynchophylline on behavior of zebrafish with Alzheimer disease

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中国药理学与毒理学杂志 2021年第9期35卷 643-644页

作者： LIU Kai-fei WU Shi-min LI Xun-yi HUANG Yao GUAN Guo-kai HUANG Xue-hong chen yi-fei Guilin Medical University Guilin 541000China

OBJECTIVE To investigate the effect of rhynchophylline on behavior of zebrafish with Alzheimer disease induced by ***⁃ODS Take a video of the zebrafish before train⁃ing,which is convenient for judging whether the zebrafish has been trained ***,the zebrafish were trained for 7 *** 60 zebraf⁃ish that were successfully trained were randomly divided into 6 groups:normal group,model group,positive group,low-dose rhynchophylline group,middle-dose group,and high-dose *** normal group was video-recorded,while the model group,positive group,low-dose group,middle-dose group,and high-dose group were given AlCl3 for *** that,the model group was videotaped,and the other groups were given drug *** the positive group and the rhynchophylline administration group were administered for 6 d,and finally all the administration groups were *** all the video is finished,the behavioral analysis software smart 3.0 was used for behavioral anal⁃ysis,and conclusions are drawn by analyzing the *** The data of the 6 groups of zebrafish staying in the red short arm area were used for comparative analysis:there was a signif⁃icant difference between the normal group and the model group(P0.05),while the model group is only significantly different

关键词： rhynchophylline Alzheimer disease zebrafish behavioral analysis

碟式太阳能光热发电系统机架结构风振响应的时域分析

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振动与冲击 2016年第7期35卷 177-185页

作者：颜健彭佑多易陈斐湖南科技大学机械设备健康维护省重点实验室湖南湘潭411201

针对大型碟式光热系统抗风运行的机架风致振动问题,以研制的25 k W级碟式机架为对象,阐述了复杂机架结构的有限元建模方法,并通过静力承载和机构传动角的分析,指出了高度角驱动机构的不足并予以改进,进而对比分析了改进前后机架多高度... 详细信息

针对大型碟式光热系统抗风运行的机架风致振动问题,以研制的25 k W级碟式机架为对象,阐述了复杂机架结构的有限元建模方法,并通过静力承载和机构传动角的分析,指出了高度角驱动机构的不足并予以改进,进而对比分析了改进前后机架多高度角工况的自振特性;基于线性滤波AR法模拟得到25组工况的脉动风载荷(平均风速16.0m/s),开展了改进机架的风振时域求解。分析了机架关键节点的位移响应均方根和峰值分布特征,并对典型工况的机架位移响应进行频谱分析,给出了各工况机架关键节点的位移风振系数,为机架结构设计提供参考。结果表明,机架结构位移响应是以脉动载荷的强迫振动为主,并伴有多阶振型参与的共振响应;机架控制点的位移峰值和位移均方根的分布特征相似,且沿焦轴的响应分量均占主导地位,机架振动主要为机架视日部分绕高度角轴线的旋转运动。

关键词：碟式光热发电机架结构脉动风场模拟风振响应时域分析机构传动角

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鹭鸟对茶园的生态影响

生态环境 2005年第6期14卷 941-944页

作者：陈易飞苏州农业职业技术学院江苏苏州215008

目前国内对鹭鸟(夜鹭Nycticoraxnyticorax、白鹭Egrettagarzetta、苍鹭Ardeacinerea、池鹭Ardeolebacchus)的迁徙、觅食习性和繁殖规律的已有详细的研究报道,但鹭鸟自身活动对栖息地的生态影响尚未见报道。作者对鹭鸟对茶园土壤和茶树... 详细信息

目前国内对鹭鸟(夜鹭Nycticoraxnyticorax、白鹭Egrettagarzetta、苍鹭Ardeacinerea、池鹭Ardeolebacchus)的迁徙、觅食习性和繁殖规律的已有详细的研究报道,但鹭鸟自身活动对栖息地的生态影响尚未见报道。作者对鹭鸟对茶园土壤和茶树的影响进行了研究,结果表明,大量鹭鸟活动所产生的鸟粪对栖息地的茶树土壤中各种养分的质量分数产生了重大影响:有机质提高了28.03%～62.25%,土壤速效磷增加了1.7～4.2倍,土壤水溶性盐提高了6～21倍之多,并发生了严重盐化;pH表土升高0.43,下层降低了1.11。对茶树的重大影响表现为:叶绿素a、叶绿素b以及总的质量分数,分别减少25.72%、36.97%、29.54%;叶子正面皮孔也被堵塞,生长发育受阻,叶子边缘、叶尖等处发生焦枯;影响轻的茶芽中茶多酚的质量分数下降了3.7%,水浸出物的质量分数略高1%,氨基酸的质量分数提高7.4%;影响严重的茶树的生物产量降低达76%以上,局部经济产量为零,甚至茶树濒临枯死。

关键词：鹭鸟夜鹭(Nycticorax nyticorax) 白鹭(Egretta gatzetta) 苍鹭(Ardea cinerea) 池鹭(Ardeole bacchus) 土壤茶(Camellia sinensis L.) 鸟粪生态

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自动刷花机的嵌入式控制系统设计

制造业自动化 2011年第4期33卷 45-48页

作者：陈益飞盐城工学院盐城224051

本文从自动刷花机的原理出发,剖析了刷花内部结构。详细的分析了自动刷花机控制原理,以嵌入式ARM核S3C2410处理器为控制器核心,在WINDOWS CE系统上进行了控制系统设计。

关键词：刷花机控制器 WINDOWS CE 系统设计