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Comprehensive insight into the occurrence characteristics,influencing factors and risk assessments of antibiotics in the Chaohu Basin

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Frontiers of environmental science & Engineering 2024年第5期18卷 57-71页

作者： Shuanggang Hu Hongzhi Zhang Yongjie Yang Kangping Cui Junjie Ao Xuneng tong Mengchen Shi Yi wang Xing chen chenxuan Li Yihan chen school of Resources and environmental Engineering Hefei University of TechnologyHefei230009China Ministry of Education-shanghai Key Laboratory of Children’s environmental Health Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai200092China Department of Civil & environmental Engineering National University of SingaporeSingapore117576Singapore College of Resources and Environment Anhui Agricultural UniversityHefei230036China

The pollution of antibiotics in aquatic environments has received extensive ***,research on antibiotic contamination in river-lake systems,a significant form of modern aquatic environments,still needs to be *** study focuses on the Chaohu Basin(china)investigating the occurrence characteristics,influencing factors,and risk assessments of antibiotics in the river-lake *** total antibiotic concentrations in the water phase and sediment phase were 3.14–1887.49 ng/L and 0.92–1553.75 ng/g,*** was the predominant antibiotic in the water phase,whereas tetracycline prevailed in the sediment *** differences in concentration and structural composition of antibiotics between the tributaries(river system)and Chaohu Lake were observed,indicating the involvement of various geochemical processes in the attenuation of antibiotics during transport to the receiving *** analysis suggested that the western river is the primary source of antibiotics in Chaohu *** nutrient influx in heavily polluted areas is crucial to addressing the escalating issue of antibiotic pollution in the river-lake *** widespread occurrence of clindamycin in the waters is likely due to wastewater treatment plant discharges,and high-intensity human activities continue to exacerbate antibiotic *** assessment indicated that sulfamethoxazole,tetracycline,lincomycin,and clindamycin ranked in the top four with the highest risks to the most sensitive aquatic ***,the antibiotics presented no risk to consumer *** study provides valuable insights for controlling antibiotic pollution in riverlake systems.

关键词： Antibiotics Occurrence characteristics Influencing factors Risk assessments River-lake system

Suppression of host plant defense by bacterial small RNAs packaged in outer membrane vesicles

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Plant Communications 2024年第4期5卷 252-254页

作者： Yan wu Sai wang Peihong wang Wenhan Nie Iftikhar Ahmad Panagiotis F.Sarris Gongyou {3. Bo Zhu shanghai Yangtze River Delta Eco-environmental Change and Management Observation and Research Station Shanghai Cooperative Innovation Center for Modern Seed Industry School of Agriculture and Biology Shanghai Jiao Tong University Shanghai China Department of environmental sciences COMSATS University Islamabad Vehari-Campus Vehari 61100 Pakistan Department of Biology University of Crete 714 09 Heraklion Crete Greece shanghai jiao tong {3. Chongqing Research Institute Shanghai China

(Plant Communications 5,100817;April 82024)After a careful,in-depth examination,the authors found some additional errors in the published *** revision,the authors created a mutant DXosr001(in which the full-length Xosr001 was deleted)and a mutant DXosr001’(in which the predicted binding motif of Xosr001 was deleted)as shown in Figure S4 of the original *** RNA-FISH assays,Xosr001 transcript could not be detected in leaves inoculated with DXosr001-OMVs,while leaves inoculated with WT-and DXosr001’-OMVs could emit green fluorescence.

关键词： deleted Figure outer

Rapid Fabrication of Electrodes for Symmetrical Solid Oxide Cells by Extreme Heat Treatment

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Energy & environmental Materials 2024年第05期7卷 353-360页

作者： Weiwei Fan Zhu Sun Manxi wang Manxian Li Yuming chen Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education School of Energy and Environment Southeast University Department of Nuclear science and Engineering Massachusetts Institute of Technology Cambridge school of Materials science and Engineering Shanghai Jiao Tong University Zhangjiang Institute for Advanced Study (ZIAS) Shanghai Jiao Tong University College of environmental science and Engineering and College of Physics and Energy Fujian Normal University

Symmetrical solid oxide cells （SSOCs） are very useful for energy generation and conversion. To fabricate the electrode of SSOC, it is very time-consuming to use the conventional approach. In this work, we design and develop a novel method, extreme heat treatment （EHT）, to rapidly fabricate electrodes for SSOC. We show that by using the EHT method, the electrode can be fabricated in seconds （the fastest method to date）, benefiting from enhanced reaction kinetics. The EHT-fabricated electrode presents a porous structure and good adhesion with the electrolyte. In contrast, tens of hours are needed to prepare the electrode by the conventional approach, and the prepared electrode exhibits a dense structure with a larger particle size due to the lengthy treatment. The EHT-fabricated electrode shows desirable electrochemical performance. Moreover, we show that the electrocatalytic activity of the perovskite electrode can be tuned by the vigorous approach of fast exsolution,deriving from the increased active sites for enhancing the electrochemical reactions. At 900℃, a promising peak power density of 966mWcm-2is reached. Our work exploits a new territory to fabricate and develop advanced electrodes for SSOCs in a rapid and high-throughput manner.

关键词： electrochemical performance extreme heat treatment perovskite electrode symmetrical solid oxide cells

Wild soybean(Glycine soja)transcription factor GsWRKY40 plays positive roles in plant salt tolerance

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The Crop Journal 2024年第3期12卷 766-775页

作者： Minglong Li Man Xue Huiying Ma Peng Feng tong chen Xiaohuan Sun Qiang Li Xiaodong Ding Shuzhen Zhang Jialei Xiao Key Laboratory of Agricultural Biological Functional Genes Northeast Agricultural UniversityHarbin 150030HeilongjiangChina Key Laboratory of Soybean Biology of Chinese Education Ministry Northeast Agricultural UniversityHarbin 150030HeilongjiangChina Department of Plant science School of Agriculture and BiologyShanghai Jiao Tong UniversityShanghai 200240China College of Life science Leshan Normal UniversityLeshan 614000SichuanChina Mudanjiang Branch of Heilongjiang Academy of Agricultural sciences Mudanjiang 157401HeilongjiangChina

Wild soybean(Glycine soja),a relative of cultivated soybean,shows high adaptability to adverse environmental *** identified and characterized a wild soybean transcription factor gene,GsWRKY40,that promotes plant salt ***40 was highly expressed in wild soybean roots and was up-regulated by salt ***40 was localized in nucleus and demonstrated DNA-binding activities but without transcriptional *** and overexpression of GsWRKY40 altered salt tolerance of Arabidopsis *** understand the molecular mechanism of GsWRKY40 in regulating plant salt resistance,we screened a cDNA library and identified a GsWRKY40 interacting protein GsbHLH92 by using yeast two-hybrid *** physical interaction of GsWRKY40 and GsbHLH92 was confirmed by co-immunoprecipitation(co-IP),GST pull-down,and bimolecular fluorescence complementation(BiFC)***,co-overexpression of GsWRKY40 and GsbHLH92 resulted in higher salt tolerance and lower ROS levels than overexpression of GsWRKY40 or GsbHLH92 in composite soybean plants,suggesting that GsWRKY40 and GsbHLH92 may synergistically regulate plant salt resistance through inhibiting ROS ***-PCR data indicated that the expression level of GmSPOD1 gene encoding peroxidase was cooperatively regulated by GsWRKY40 and GsbHLH92,which was confirmed by using a dual luciferase report system and yeast one-hybrid *** study reveals a pathway that GsWRKY40 and GsbHLH92 collaboratively up-regulate plant salt resistance through impeding GmSPOD1 expression and reducing ROS levels,providing a novel perspective on the regulatory mechanisms underlying plant tolerance to abiotic stresses.

关键词： Wild soybean Transcription factor Salt stress ROS

Psychosocial Stress Modifies the Acute Cardiac Health Effects of Traffic-Related Air Pollution

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Environment & Health 2024年第1期2卷 11-22页

作者： tongjun Guo Wanzhou wang Xi chen Huaqi Guo Kai wang Yating Ma Hongyan Deng Xianggui Li Anqi Shan Qian wu Yaoyan Li Hongyu Li Qisijing Liu Juan chen Yang Lan Jian Lei Furong Deng Zhiwei Sun Xinbiao Guo Shaowei wu Yan wang Naijun Tang Department of Occupational and environmental Health sciences School of Public HealthPeking UniversityBeijing 100191China Department of Occupational and environmental Health Tianjin Key Laboratory of EnvironmentNutrition and Public HealthSchool of Public HealthTianjin Medical UniversityTianjin 300070China Department of Respiratory and Critical Care Medicine The Ninth People’s Hospital of Shanghai Jiao Tong University School of MedicineShanghai 200025China Department of Occupational and environmental Health School of Public HealthXi’an Jiaotong University Health Science CenterXi’anShaanxi 710049China Key Laboratory of Trace Elements and Endemic Diseases in Ministry of Health Xi’anShaanxi 710049China Key Laboratory for Disease Prevention and Control and Health Promotion of Shaanxi Province Xi’anShaanxi 710049China Institute of Social Psychology School of Humanities and Social SciencesXi’an Jiaotong UniversityXi’anShaanxi 710049China Qinglongqiao Community Health Service Centre Beijing 100091China Key Laboratory of Environment and Genes Related to Diseases(Xi’an jiaotong university) Ministry of EducationXi’an 710061China school of Public Health Shanghai Jiao Tong University School of MedicineShanghai 200025China Department of HAI Management Tianjin Huanhu HospitalTianjin 300060China Office for National Clinical Research Center for Geriatric Diseases Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing 100005China Research Institute of Public Health School of MedicineNankai University300071 TianjinChina Department of Toxicology and Sanitary Chemistry School of Public HealthCapital Medical UniversityBeijing 100069China Beijing Key Laboratory of environmental Toxicology Capital Medical UniversityBeijing 100069China The Ninth People’s Hospital of shanghai jiao tong university school of Medicine Shanghai 200011China

Previous studies have shown that exposure to black carbon(BC,a tracer of traffic-related air pollution)and psychosocial stress are both associated with adverse cardiac effects,but whether psychosocial stress could modify the cardiac effects of BC is *** investigate the potential modifying effect of psychosocial stress on the associations between acute exposure to BC and typical cardiac health variables,real-time personal 24 h measurements were conducted in a repeated-measure study among adults with elevated blood pressure(high-risk group)and a panel study among normal adults(low-risk group)in *** cardiac health variables included ST-segment depression events,heart rate,and heart rate variability(HRV)*** Stress Scale,State Anxiety Inventory and Self-rating Depression Scale were used to assess the recent psychosocial stress status of the participants,and a composite stress index was established based on these *** linear mixed-effects model was used to analyze the associations between BC exposure and cardiac health variables and potential effect modification by psychosocial stress.A total of 9724 h measurements among 97 participants in the repeated-measure study and 20224 h measurements among 87 participants in the panel study were included in the final *** BC exposure was significantly associated with increased ST-segment depression events and heart rate and decreases in HRV in both *** marginal effects of acute BC exposure on most cardiac health variables generally tended to be amplified under higher vs low levels of psychosocial stress in both studies,with the composite stress index apparently modifying the associations of BC exposure with most ST-segment depression events and HRV *** findings suggest that psychosocial stress may increase the participants’cardiac susceptibility to BC exposure,which could be helpful for the identification of susceptible individuals in the context of traff

关键词： Air pollution Black carbon Cardiac health Effect modification Psychosocial stress

Prospective Cohort Investigation on Physical Activity of Osteoporosis Outcomes(PAOPO)in Jidong:Objectives,Study Design,and Baseline Characteristics

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Biomedical and environmental sciences 2024年第9期37卷 1067-1079页

作者： Jingzhi Yang Hao Shen Sicheng wang Long Bai Zhen Geng Yingying Jing Ke Xu Yuhe Liu Wenqian wu Hao Zhang Yuanwei Zhang Zuhao Li Chuandong wang Guangchao wang Xiao chen Jiacan Su Institute of Translational Medicine Shanghai UniversityShanghai 200444China Orthopedic Department of Xinhua Hospital affiliated to shanghai jiaotong {3. school of Medicine Shanghai 200092China Department of Orthopedics Trauma Shanghai Zhongye HospitalShanghai 200941China Clinical Research Institute Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China

Objective The aim of this study was to investigate the prospective association between physical activity(PA),independently or in conjunction with other contributing factors,and osteoporosis(OP)*** The Physical Activity in Osteoporosis Outcomes(PAOPO)study was a community-based cohort investigation.A structured questionnaire was used to gather the participants’sociodemographic *** mineral density(BMD)measurements were performed to assess OP outcomes,and the relationship between BMD and OP was evaluated within this *** From 2013.to 2014,8,471 participants aged 18 years and older were recruited from Tangshan,china’s Jidong *** on their PA level,participants were categorized as inactive,moderately active,or very *** showed higher physical exercise levels than women across the activity *** was significantly higher in the very active group than in the moderately active and inactive *** aged>50 years are at a higher risk of developing OP and *** The PAOPO study offers promising insights into the relationship between PA and OP outcomes,encouraging the implementation of PA in preventing and managing OP.

关键词： Osteoporosis Physical activity Risk factors Cohort study

DeepSecE:A Deep-Learning-Based Framework for Multiclass Prediction of Secreted Proteins in Gram-Negative Bacteria

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Research 2024年第3期2023卷 243-257页

作者： Yumeng Zhang Jiahao Guan chen Li Zhikang wang Zixin Deng Robin BGasser Jiangning Song Hong-Yu Ou state Key Laboratory of Microbial Metabolism Joint International Laboratory on Metabolic&Developmental SciencesSchool of Life Sciences and BiotechnologyShanghai Jiao Tong UniversityShanghai 200240China shanghai Key Laboratory of Veterinary Biotechnology Shanghai Jiao Tong UniversityShanghai 200240China Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology Monash UniversityMelbourneViC 3800Australia Monash Data Futures Institute Monash UniversityMelbourneViC 3800Australia Melbourne Veterinary school Faculty of ScienceThe University of MelbourneParkvilleVIC 3010Australia.

Proteins secreted by Gram-negative bacteria are tightly linked to the virulence and adaptability of these microbes to environmental *** identification of such secreted proteins can facilitate the investigations of infections and diseases caused by these bacterial ***,current bioinformatic methods for predicting bacterial secreted substrate proteins have limited computational efficiency and application scope on a genome-wide ***,we propose a novel deep-learning-based framework—DeepSecE—for the simultaneous inference of multiple distinct groups of secreted proteins produced by Gram-negative *** remarkably improves their classification from nonsecreted proteins using a pretrained protein language model and transformer,achieving a macro-average accuracy of 0.883.on 5-fold *** benchmarking suggests that DeepSecE achieves competitive performance with the state-of-the-art binary predictors specialized for individual types of secreted *** attention mechanism corroborates salient patterns and motifs at the N or C termini of the protein *** this pipeline,we further investigate the genome-wide prediction of novel secreted proteins and their taxonomic distribution across~1,000 Gram-negative bacterial *** present analysis demonstrates that DeepSecE has major potential for the discovery of disease-associated secreted proteins in a diverse range of Gram-negative *** online web server of DeepSecE is also publicly available to predict and explore various secreted substrate proteins via the input of bacterial genome sequences.

关键词： Deep server competitive

Association of Human Whole-blood NAD+Levels with Nabothian Cyst

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Biomedical and environmental sciences 2024年第5期37卷 471-478页

作者： XU ling wang Yue Xuan wang Wei FAN Xue {3. Xue Yu ZHOU Tian Yun LIU Yu He YU Ye YANG Fan JU Zhen Yu ZHOU Yong wang Deng Liang Clinical Research Institute Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China NHC Key Lab of Reproduction Regulation Shanghai Engineering Research Center of Reproductive Health Drugs and DevicesShanghai Institute for Biomedical and Pharmaceutical TechnologiesShanghai 200237China Department of Applied Statistics Johannes Kepler University LinzLinz 4040Austria Hematology Center Beijing Key Laboratory of Pediatric Hematology OncologyNational Key Discipline of Pediatrics(Capital Medical University)Key Laboratory of Major Diseases in ChildrenMinistry of EducationBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of Biostatistics School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012ShandongChina Clinical Medicine School of Basic MedicineShanghai Medical College Fudan UniversityShanghai 200032China Department of Biochemistry and Molecular Biology Hengyang Medical SchoolUniversity of South ChinaHengyang 421001HunanChina Administrative Office Total Quality Management OfficeTotal Quality Management InstituteShanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China The First Affiliated Hospital of Jinan university Institute of Aging and Regenerative MedicineJinan UniversityJinan 510632GuangzhouChina Department of Scientific Research The First Affiliated Hospital of Huzhou UniversityHuzhou 313000ZhejiangChina Department of Neurosurgery Neurosurgery Research InstituteThe First Affiliated HospitalFujian Medical UniversityFuzhou 350005FujianChina Department of Neurosurgery Binhai Branch of National Regional Medical CenterThe First Affiliated HospitalFujian Medical UniversityFuzhou 350209FujianChina Fujian Provincial Institutes of Brain Disorders and Brain sciences The First Affiliated HospitalFujian Medical UniversityFuzhou 350005FujianChina Fujian Provincial Clinical Research Center for Neurological

Objective Little is known about the association between whole-blood nicotinamide adenine dinucleotide(NAD^(+))levels and nabothian *** study aimed to assess the association between NAD^(+)levels and nabothian cysts in healthy Chinese *** Multivariate logistic regression analysis was performed to analyze the association between NAD^(+)levels and nabothian *** The mean age was 43.0±11.5 years,and the mean level of NAD^(+)was 3..3.5.3.mol/*** cysts occurred in 184(27.7%)participants,with single and multiple cysts in 100(15.0%)and84(12.6%)participants,*** total nabothian cyst prevalence gradually decreased from3..4%to 21.6%from Q1 to Q4 of NAD^(+)and the prevalence of single and multiple nabothian cysts also decreased across the NAD^(+)*** compared with the highest NAD^(+)quartile(≥3..4μmol/L),the adjusted odds ratios with 95%confidence interval of the NAD^(+)Q1 was 1.89(1.14–3.14)for total nabothian *** risk of total and single nabothian cysts linearly decreased with increasing NAD^(+)levels,while the risk of multiple nabothian cysts decreased more rapidly at NAD^(+)levels of 28.0 to3..0μmol/***:Low NAD^(+)levels were associated with an increased risk of total and multiple nabothian cysts.

关键词： Nicotinamide adenine dinucleotide Nabothian cyst Female Risk factor

Understanding the role of transition metal single-atom electronic structure in oxysulfur radical-mediated oxidative degradation

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environmental science and Ecotechnology 2024年第4期20卷 247-258页

作者： Guanshu Zhao Jing Ding Jiayi Ren Qingliang Zhao chengliang Mao Kun wang Jessica Ye Xueqi chen Xianjie wang Mingce Long State Key Laboratory of Urban Water Resources and Environment School of EnvironmentHarbin Institute of TechnologyHarbin150090China Solar Fuels Group Department of ChemistryUniversity of Toronto80 St.George StreetTorontoOntarioM5S 3H6Canada school of Physics Harbin Institute of TechnologyHarbin150001China school of environmental science and Engineering Key Laboratory of Thin Film and Microfabrication Technology(Ministry of Education)Shanghai Jiao Tong University800 Dongchuan RoadShanghai200240China

The ubiquity of refractory organic matter in aquatic environments necessitates innovative removal *** radical-based advanced oxidation has emerged as an attractive solution,offering high selectivity,enduring efficacy,and anti-interference *** many technologies,sulfite activation,leveraging its cost-effectiveness and lower toxicity compared to conventional persulfates,stands ***,the activation process often relies on transition metals,suffering from low atom *** we introduce a series of single-atom catalysts(SACs)employing transition metals on g-C_(3.N_(4)substrates,effectively activating sulfite for acetaminophen *** highlight the superior performance of Fe/CN,which demonstrates a degradation rate constant significantly surpassing those of Ni/CN and Cu/*** investigation into the electronic and spin polarization characteristics of these catalysts reveals their critical role in catalytic efficiency,with oxysulfur radical-mediated reactions ***,under visible light,the catalytic activity is enhanced,attributed to an increased generation of oxysulfur radicals and a strengthened electron donation-back donation *** proximity of Fe/CN's d-band center to the Fermi level,alongside its high spin polarization,is shown to improve sulfite adsorption and reduce the HOMO-LUMO gap,thereby accelerating photo-assisted sulfite *** work advances the understanding of SACs in environmental applications and lays the groundwork for future water treatment technologies.

关键词： Single-atom catalysts(SACs) Oxysulfur radical Sulfite activation Spin polarization Electronic structure