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Historical perspective of syphilis in the past 60 years in China： eliminated, forgotten, on the return

Chinese Medical Journal 2013年第14期126卷 2774-2779页

作者： chen xiang-sheng yin yue-ping wang qian-qiu wang bao-xi National Center for STD Control and Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College Nanjing Jiangsu 210042 China

Syphilis （historically called lues） is a sexually transmitted disease （STD） caused by the spirochete bacteriumTreponema pallidum subspecies pallidum. Syphilis had many alternate names, such as the ＂great pox＂ in order to distinguish it from smallpox, and was given many national attributions, such as the French pox, the English pox, and the Italian pox, due to the disease often being spread by foreign sailors and soldiers during their frequent,

关键词： syphilis epidemic elimination control

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Efficacy and safety of sirolimus early conversion protocol in liver transplant patients with hepatocellular carcinoma:A single-arm, multicenter, prospective study

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Hepatobiliary & Pancreatic Diseases International 2022年第2期21卷 106-112页

作者： Ren-Yi Su Sun-Bin Ling Qiao-Nan Shan Xu-Yong Wei Rui wang Chang-Ku Jia Li Zhuang Tian Shen Li-Min Ding Zhi-Dan Xu Lai-Bang Luo Li-Bo Sun Guang-Ming Li Tai-Shi Fang Nan Jiang Kun Zhang Zhao-Jie Su Zhi-Hai Peng Ren Lang Tao Jiang qiang He Lin-Sen Ye Yang Yang Yu-Ting He Wen-Zhi Guo Liu-Gen Lan Xu-Yong Sun Dong chen Zhi-Shui chen Da-Wei Zhou Shao-Jun Ye Qi-Fa Ye Min Tian Jian-Hua Shi Bo wang Jiang Liu qian Lu Wei Rao Jin-Zhen Cai Tao Lv Jia-yin Yang Pu-Sen wang Lin Zhong Jing-sheng Ma Qi-Gen Li sheng-Dong Wu Chang-Jiang Lu Cai-De Lu Dong-Hua Zhang Xuan wang Zi-qiang Li Mu-Jian Teng Jun-Jie Li Wen-Tao Jiang Jian-Hua Li Quan-bao Zhang Ning-Qi Zhu Zheng-xin wang Kang He qiang xia Shao-Hua Song Zhi-Ren Fu Wei qiu Guo-yue Lv Rui-Peng Song Ji-Zhou wang Zheng wang Jian Zhou Gang chen ying-Peng Zhao Li Li Ze-Min Hu Qi-Jie Luo Zhong-Zhou Si Bin xie xiao-Shun He Zhi-Yong Guo Shu-Sen Zheng xiao Xu Department of Hepatobiliary and Pancreatic Surgery The Center for Integrated Oncology and Precision MedicineAffiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006China NHC Key Laboratory of Combined Multi-organ Transplantation Hangzhou 310003China Department of Hepatobiliary and Pancreatic Surgery Shulan(Hangzhou)HospitalZhejiang Shuren University School of MedicineHangzhou 310022China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Transplantation Jiangxi Provincial People’s Hospital Affiliated to Nanchang UniversityNanchang 330006China Liver Transplantation Center Beijing You’an HospitalCapital Medical UniversityBeijing 100069China Department of Hepatic Surgery National Clinical Research Center for Infectious DiseaseShenzhen Third People’s HospitalThe Second Affiliated Hospital of Southern University of Science and TechnologyShenzhen 518112China Department of General Surgery Xiang’an Hospital of Xiamen UniversityXiamen 361000China Deartment of Hepatobiliary and Pancreaticosplenic Surgery Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China Department of Hepatic Surgery and Liver Transplantation Center The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of Liver Transplantation The Second Affiliated Hospital of Guangxi Medical UniversityNanning 530000China Institute of Organ Transplantation Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Institute of Hepatobiliary Diseases of Wuhan University Transplant Center of Wuhan UniversityHubei Key Laboratory of Medical Technology on TransplantationZhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Hepatobiliary Surgery The First Affiliated Hos

Mammalian target of rapamycin(m TOR) inhibitor as an attractive drug target with promising antitumor effects has been widely investigated. High quality clinical trial has been conducted in liver transplant(LT) recipients in Western countries. However, the pertinent studies in Eastern world are paucity. Therefore, we designed a clinical trial to test whether sirolimus can improve recurrence-free survival(RFS) in hepatocellular carcinoma(HCC) patients beyond the Milan criteria after LT. This is an open-labeled, single-arm, prospective, multicenter, and real-world study aiming to evaluate the clinical outcomes of early switch to sirolimus-based regimens in HCC patients after LT. Patients with a histologically proven HCC and beyond the Milan criteria will be enrolled. The initial immunosuppressant regimens are center-specifc for the frst 4-6 weeks. The following regimens integrated sirolimus into the regimens as a combination therapy with reduced calcineurin inhibitors based on the condition of patients and centers. The study is planned for 4 years in total with a 2-year enrollment period and a 2-year follow-up. We predict that sirolimus conversion regimen will provide survival benefts for patients particular in the key indicator RFS as well as better quality of life. If the trial is conducted successfully, we will have a continued monitoring over a longer follow-up time to estimate indicator of overall survival. We hope that the outcome will provide better evidence for clinical decision-making and revising treatment guidelines based on Chinese population data.

关键词： Sirolimus Immunosuppressive agents Hepatocellular carcinoma Liver transplantation Conversion

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不同病理类型淋巴瘤骨髓侵犯的发生率

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中国实验血液学杂志 2018年第3期26卷 765-771页

作者：陈青朱璐婷岑溪南梁赜隐欧晋平王莉红王文生刘薇邱志祥董玉君王茫桔孙玉华尹玥王倩任汉云北京大学第一医院血液科北京100034 北京市顺义区医院血液科北京101300

目的:分析不同病理类型淋巴瘤骨髓侵犯(BMI)的发生率。方法:回顾性分析我院2000年10月-2016年9月经组织病理确诊的702例淋巴瘤患者的骨髓检查结果。以骨髓穿刺涂片、骨髓活检、流式细胞术及^(18)F-FDG PET/CT中任何一项检查方法阳性即... 详细信息

目的:分析不同病理类型淋巴瘤骨髓侵犯(BMI)的发生率。方法:回顾性分析我院2000年10月-2016年9月经组织病理确诊的702例淋巴瘤患者的骨髓检查结果。以骨髓穿刺涂片、骨髓活检、流式细胞术及^(18)F-FDG PET/CT中任何一项检查方法阳性即判定为淋巴瘤骨髓侵犯。结果:非霍奇金淋巴瘤(NHL)骨髓侵犯发生率明显高于霍奇金淋巴瘤(HL)[32.6%(201/616)vs 15%(13/86)](P<0.05)。NHL中B细胞淋巴瘤骨髓侵犯发生率明显高于T细胞淋巴瘤[37.0%(159/430)vs 22.6%(42/186)](P<0.05)。按不同病理类型分析,套细胞淋巴瘤骨髓侵犯发生率为88%(22/25),滤泡性淋巴瘤骨髓侵犯发生率为38.5%(15/39),弥漫大B细胞淋巴瘤骨髓侵犯发生率为21.8%(56/257),肝脾T细胞淋巴瘤骨髓侵犯发生率为100%(5/5)。结论:不同病理类型淋巴瘤骨髓侵犯发生率差异较大。对初诊淋巴瘤患者进行骨髓评价对淋巴瘤的分期具有重要意义。

关键词：淋巴瘤骨髓侵犯发生率病理类型

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Consensus statement on layout and delivery of automatic external defibrillator in China

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Journal of Hainan Medical University 2020年第15期26卷 18-23页

作者： Yu Cao Song chen Yan-Fen Chai xiao-Hui chen Yu-Guo chen Shao-Wen cheng Wen-Wei cheng Bang-Han Ding Yang Deng Jie Fu Bang-Jiang Fang Mai-ying Fan Li Gui ping Gong Wei Guo Shu-Bin Guo Liang Huang Ji-Yuan Han Zhong Ji xian-Fei Ji xin-Cai Ji Hong-Xu Jin xin-Jun Jiang wang-xiang Jiang Jia-Liang Liu xiao-Ran Liu Zhi Liu Chuan-Zhu Lv Feng Lu Tan-Shi Li xin Li Yong Li Shang-Lun Li Shuang-Ming Li xiao-Gang Li bao-Jun Li Pei-Wu Li Chun-sheng Li Zhi-Jun Li Chang-Luo Li xiang-Min Li yin-ping Li Zong-Jun Lu Zu-Xun Lu Zhong-qiu Lu Zhi-qian Luo xiao-xing Liao Jian-Bo Lei Tao Ma Yu Ma yue-Feng Ma Qing-Bian Ma Lin-Hao Ma Jun-Qi Ma Shi-Nan Nie Jie-Miao Ou-Yang Peng Peng Qiao Pei Shu-Ming Pan Guo-Zhong Qing Li-Jie Qin Wu-ying Qiao Fei Shao Wei Song xing-yue Song Zhen-Ju Song Rong-Ju Sun De-Ya Shang Du-Juan Sha Gui-Lan Tao Guo-Gang Tian ying-ping Tian Jian-Guang Tian Chao-Yang Tong Zi-Ren Tang Meng-xiong Tang Guo-ping Wu Zhi Wan Tao wang xin wang Peng wang Zhong wang Tong wang Ri-xing wang Yi-xin wang xiao-Dan wang Ling Wu Wei Wei Hua xiang Feng Xu Jun Xu Jie Xu Miao-Rong xie Shuo-Gui Xu Tie Xu Feng Yu Wen Yi Li-Shan Yang Shi-Jiao Yan Jin-Jian Yao Shou-Chun Yan Xue-Zhong Yu xian-Zhi Ye xian-Liang Yan Fu-Bing Zhou Rong-Bin Zhou Ming Zhou qiang Zhou Jin Zhou ping Zhou Chang-Ju Zhu Hua-Dong Zhu Ji-Hong Zhu Hong Zhang Mao Zhang Hua Zhang Na Zhang Guo-qiang Zhang Guo-xiu Zhang Jin-Song Zhang Wen-Wu Zhang Wen-Zhong Zhang Jian-Feng Zhang Yi-Min Zhu Jun Zeng Yuan Zheng Zhi-Jie Zheng Shen Zhao Yan Zhao Min Zhao Bin Zhao xiao-Dong Zhao xiao-Jing Zhao Hong-Ke Zeng sheng-qiang Zou The Chinese Society of Emergency Medicine Research Unit of Island Emergency Medicine Chinese Academy of Medical SciencesHainan Medical University Key Laboratory of Emergency and Trauma of Ministry of Education Hainan Medical UniversityHaikouHainanChina Emergency and Trauma College Hainan Medical UniversityHaikouHainanChina Department of Emergency Hainan Clinical Research Center for Acute and Critical DiseasesThe Second Affiliated Hospital of Hainan Medical UniversityHaikouHainanChina Key Laboratory of Hainan Trauma and Disaster Rescue Key Laboratory of Trauma of Hainan Medical University

*** Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac *** is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].

关键词： cardiac death respiratory

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