检索结果-南通市图书馆

Efficacy of exercise rehabilitation for managing patients with Alzheimer's disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第10期19卷 2175-2188页

作者： Dan Li Jinning Jia Haibo Zeng Xiaoyan zhong Hui chen chenju Yi Department of Pathology The First Affiliated Hospital of Gannan Medical UniversityGanzhouJiangxi ProvinceChina Department of Pathology Huichang County People’s HospitalGanzhouJiangxi ProvinceChina School of Life Sciences Faculty of ScienceUniversity of Technology SydneyUltimoNSWAustralia Research Center The Seventh Affiliated Hospital of Sun Yat-sen UniversityShenzhenGuangdong ProvinceChina Shenzhen Key Laboratory of Chinese Medicine Active Substance Screening and Translational Research ShenzhenGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Brain Function and Disease GuangzhouGuangdong ProvinceChina

Alzheimer's disease(AD) is a progressive and degenerative neurological disease characterized by the deterioration of cognitive functions. While a definitive cure and optimal medication to impede disease progression are currently unavailable, a plethora of studies have highlighted the potential advantages of exercise rehabilitation for managing this condition. Those studies show that exercise rehabilitation can enhance cognitive function and improve the quality of life for individuals affected by AD. Therefore, exercise rehabilitation has been regarded as one of the most important strategies for managing patients with AD. Herein, we provide a comprehensive analysis of the currently available findings on exercise rehabilitation in patients with AD, with a focus on the exercise types which have shown efficacy when implemented alone or combined with other treatment methods, as well as the potential mechanisms underlying these positive effects. Specifically, we explain how exercise may improve the brain microenvironment and neuronal plasticity. In conclusion, exercise is a cost-effective intervention to enhance cognitive performance and improve quality of life in patients with mild to moderate cognitive dysfunction. Therefore, it can potentially become both a physical activity and a tailored intervention. This review may aid the development of more effective and individualized treatment strategies to address the challenges imposed by this debilitating disease, especially in low-and middle-income countries.

关键词： Alzheimer's disease cerebrovascular function cognitive function epigenetic regulation exercise hippocampal neurogenesis mitochondria neuroinflammation neuronal plasticity

Arbitrarily rotating polarization direction and manipulating phases in linear and nonlinear ways using programmable metasurface

在线全文

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第9期13卷 1789-1800页

作者： Wei Liu si Ran Wang Jun Yan Dai Lei Zhang Qiao chen Qiang cheng Tie Jun Cui State Key Laboratory of Millimeter Waves Southeast UniversityNanjing 210096China Institute of Electromagnetic Space Southeast UniversityNanjing 210096China Frontiers Science Center for Mobile Information Communication and Security Southeast UniversityNanjing 210096China Electrical Engineering Department Chalmers University of TechnologyGothenburg 41258Sweden

Independent controls of various properties of electromagnetic(EM)waves are crucially required in a wide range of *** metasurface is a promising candidate to provide an advanced platform for manipulating EM ***,we propose an approach that can arbitrarily control the polarization direction and phases of reflected waves in linear and nonlinear ways using a stacked programmable ***,we extend the space-timecoding theory to incorporate the dimension of polarization,which provides an extra degree of freedom for manipulating EM *** proof-of-principle application examples,we consider polarization rotation,phase manipulation,and beam steering at linear and nonlinear *** validation,we design,fabricate,and measure a metasurface *** experimental results show good agreement with theoretical predictions and *** proposed approach has a wide range of applications in various areas,such as imaging,data storage,and wireless communication.

关键词： surface. nonlinear rotating

Semantic segmentation-based semantic communication system for image transmission

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Digital Communications and Networks 2024年第3期10卷 519-527页

作者： Jiale Wu Celimuge Wu Yangfei Lin Tsutomu Yoshinaga Lei zhong Xianfu chen Yusheng Ji The University of Electro-Communication Tokyo182-8585Japan Toyota Motor Corporation Tokyo112-8701Japan VTT Technical Research Centre of Finland OuluFinland National Institute of Informatics(NII) Tokyo101-8430Japan

With the rapid development of artificial intelligence and the widespread use of the Internet of Things, semantic communication, as an emerging communication paradigm, has been attracting great interest. Taking image transmission as an example, from the semantic communication's view, not all pixels in the images are equally important for certain receivers. The existing semantic communication systems directly perform semantic encoding and decoding on the whole image, in which the region of interest cannot be identified. In this paper, we propose a novel semantic communication system for image transmission that can distinguish between Regions Of Interest (ROI) and Regions Of Non-Interest (RONI) based on semantic segmentation, where a semantic segmentation algorithm is used to classify each pixel of the image and distinguish ROI and RONI. The system also enables high-quality transmission of ROI with lower communication overheads by transmissions through different semantic communication networks with different bandwidth requirements. An improved metric θPSNR is proposed to evaluate the transmission accuracy of the novel semantic transmission network. Experimental results show that our proposed system achieves a significant performance improvement compared with existing approaches, namely, existing semantic communication approaches and the conventional approach without semantics.

关键词： Semantic Communication Semantic segmentation Image transmission Image compression Deep learning

Vapor-phase postsynthetic amination of hypercrosslinked polymers for efficient iodine capture

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第9期35卷 320-325页

作者： Pengcheng Su Shizheng chen Zhihong Yang Ningning zhong chenzi Jiang Wanbin Li School of Materials and Chemical Engineering Anhui Jianzhu UniversityHefei 230026China School of Environment Jinan UniversityGuangzhou 511443China Jiangsu Environmental Protection Group Nantong Co. Ltd.Nantong 226010China

Hypercrosslinked polymers(HCPs)with large surface areas,high intrinsic porosities and low production costs may be available platforms for iodine ***,the lack of iodine-philicity binding sites limits their adsorption *** we use vapor-phase postsynthetic amination strategy to introduce electron-donating amino groups into the prefabricated HCPs for enhancing their iodine capture *** simple vapor-phase exposure,the halogen-containing HCPs can be grafted by amines through nucleophilic substitution toward chloro *** with the abundant amino groups and high porosities,the amino-functionalized porous polymers show substantially increased iodine adsorption capacity,about 221%as that of original one,accompanied by excellent *** investigations reveal the key roles of the electron-donor amino groups andπ-conjugated benzene rings along with structure characteristics of porous polymer frameworks in iodine ***,this vapor-phase amination strategy shows good generality and can be extended to various amines,e.g.,ethylenediamine,1,3-diaminopropane and *** work proves that this simple vapor-phase postsynthetic functionalization strategy may be applied in other porous polymers with wide application prospects in adsorption,separation and storage.

关键词： Porous polymers Postsynthetic amination Hypercrosslinked polymers Vapor-phase grafting Iodine capture

A Possible X-ray Quasi-periodic Oscillation in the Narrow-line Seyfert 1 Galaxy Mrk 142

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第6期24卷 191-200页

作者： Xiao-Gu zhong Jian-cheng Wang Yong-Yun chen Xiao-Ling Yu College of Physics and Electronic Engineering Qujing Normal UniversityQujing 655011China Yunnan Observatories Chinese Academy of SciencesKunming 650216China

A possible quasi-periodic oscillation(QPO) at frequency 7.045 × 10^(-5) Hz is found in the narrow-line Seyfert 1galaxy Mrk 142 in the data of XMM-Newton collected on 2020 April *** find that the QPO signal is statistically significantly larger than the 5σ level and highly coherent with quality factor Q > 5 at the 0.3–10 keV band by using the method of the Lomb–Scargle Periodogram,the Weighted Wavelet Z-transform and the *** analyze the data in 0.3–0.6 keV,0.6–1 keV,1–3 keV and 3–10 keV energy bands,and find obvious QPO signals at 0.3–0.6 keV and 1–3 keV *** then analyze the time-average spectra and time variability at the QPO frequency of 7.045 × 10^(-5) Hz,and use a model to fit *** find that the QPO signal mainly comes from the X-ray hot corona.

关键词： X-rays:galaxies galaxies:Seyfert accretion accretion disks radiation mechanisms:general

Satellite glial cells in sensory ganglia play a wider role in chronic pain via multiple mechanisms

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第5期19卷 1056-1063页

作者： Xiaoyun Qiu Yuanzhi Yang Xiaoli Da Yi Wang zhong chen Cenglin Xu Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province School of Pharmaceutical ScienceZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina

Satellite glial cells are unique glial cells that surround the cell body of primary sensory *** increasing body of evidence suggests that in the presence of inflammation and nerve damage,a significant number of satellite glial cells become activated,thus triggering a series of functional *** suggests that satellite glial cells are closely related to the occurrence of chronic *** this review,we first summarize the morphological structure,molecular markers,and physiological functions of satellite glial ***,we clarify the multiple key roles of satellite glial cells in chronic pain,including gap junction hemichannel Cx43,membrane channel Pannexin1,K channel subunit 4.1,ATP,purinergic P2 receptors,and a series of additional factors and their receptors,including tumor necrosis factor,glutamate,endothelin,and ***,we propose that future research should focus on the specific sorting of satellite glial cells,and identify genomic differences between physiological and pathological *** review provides an important perspective for clarifying mechanisms underlying the peripheral regulation of chronic pain and will facilitate the formulation of new treatment plans for chronic pain.

关键词： chronic pain primary sensory neurons satellite glial cells sensory ganglia

Ischemic colitis induced by a platelet-raising capsule: A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第3期12卷 607-615页

作者： chen-Lu Wang Ze-Kun si Guo-Hong Liu chen chen Hui Zhao Lei Li The Affiliated Hospital of Shandong Second Medical University School of Clinical MedicineShandong Second Medical UniversityWeifang 261000Shandong ProvinceChina Department of Gastroenterology The Affiliated Hospital of Shandong Second Medical UniversityWeifang 261000Shandong ProvinceChina

BACKGROUND Ischemic colitis(IC)is also known as colon ischemia and is caused by colon vascular occlusion or nonocclusion,which results in a reduced blood supply to the colon and is not significant enough to maintain the metabolic function of cells,leading to intestinal wall *** main symptoms include abdominal pain,diarrhea,and bloody *** severe cases,intestinal gangrene,peritonitis,intestinal stenosis and even intestinal obstruction may *** induced by long-term use of certain special drugs is relatively rare in clinical *** article describes the clinical diagnosis and treatment of a typical case and provides a new treatment idea for the treatment of *** SUMMARY The patient was admitted to the hospital with"abdominal pain for half a month and bloody stool with mucous and pus for 3 d"and was diagnosed with"IC".Symptomatic and supportive treatment,such as antibiotics(levofloxacin),acid inhibition and stomach protection,fluid replenishment,and intravenous nutrition,was *** patient's colonic ulcers were considered to be related to the oral administration of platelet(PLT)-raising capsules;the patient was asked to stop PLT-raising drugs for selective review via colonoscopy,and antibiotics and mesalazine enteric-coated tablets were *** the guidance of hematology consultation,60 mg of methylprednisolone was given in combination with PLT infusion to increase the *** treatment,the patient's condition stabilized,the patient’s stool turned yellow,the patient’s symptoms improved,and the patient was allowed to leave the *** PLT-raising capsules can lead to IC,so clinicians should have a full understanding of the application of these drugs in the treatment of various causes of thrombocyt-INTRODUCTION Ischemic colitis(IC)is also known as colon ischemia(CI)and is caused by colon vascular occlusion or nonocclusion,which results in a reduced blood supply to the colon;this process is not significant enough to maintai

关键词： Platelet-raising capsule Ischemic colitis Drug-related Colonic ulcer Case report

High-precision X-ray polarimeter based on channel-cut crystals

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第3期35卷 30-39页

作者： Shang-Yu si zhong-Liang Li Wen-Hong Jia Lian Xue Hong-Xin Luo Jian-Cai Xu Bai-Fei Shen Lin-Gang Zhang Liang-Liang Ji Yu-Xin Leng Ren-zhong Tai Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Sciences Beijing 100049China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China Shanghai Institute of Optics and Fine Mechanics Chinese Academy of SciencesShanghai 201800China

We report on using synthetic silicon for a high-precision X-ray polarimeter comprising a polarizer and an analyzer,each based on a monolithic channel-cut crystal used at multiple Brewster reflections with a Bragg angle very close to 45°.Experiments were performed at the BL09B bending magnet beamline of the Shanghai Synchrotron Radiation Facility using a si(800)crystal at an X-ray energy of 12.914 keV.A polarization purity of 8.4×10^(-9)was *** result is encouraging,as the measured polarization purity is the best-reported value for the bending magnet ***,this is the firstly systematic study on the hard X-ray polarimeter in China,which is crucial for exploring new physics,such as verifying vacuum birefringence.

关键词： X-ray polarimeter Vacuum birefringence Synchrotron radiation Channel-cut crystal

Enhancement of polymyxin B1 production by an artificial microbial consortium of Paenibacillus polymyxa and recombinant Corynebacterium glutamicum producing precursor amino acids

在线全文

学校读者我要写书评

暂无评论

Synthetic and Systems Biotechnology 2024年第1期9卷 176-185页

作者： Hui-zhong Sun si-Yu Wei Qiu-Man Xu Wei Shang Qing Li Jing-Sheng cheng Ying-Jin Yuan Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering(Ministry of Education) School of Chemical Engineering and TechnologyTianjin UniversityYaguan Road 135Jinnan DistrictTianjin300350PR China Tianjin Key Laboratory of Animal and Plant Resistance College of Life ScienceTianjin Normal UniversityBinshuixi Road 393Xiqing DistrictTianjin300387PR China Department of Pharmaceutical School of Chemical Engineering and TechnologyTianjin UniversityYaguan Road 135Jinnan DistrictTianjin300350PR China

Polymyxin B,produced by Paenibacillus polymyxa,is used as the last line of defense *** this study,exogenous mixture of precursor amino acids increased the level and proportion of polymyxin B1 in the total of polymyxin B analogs of *** CJX518-AC(PPAC)from 0.15 g/L and 61.8%to 0.33 g/L and 79.9%,*** co-culture of strain PPAC and recombinant Corynebacterium glutamicum-leu01,which produces high levels of threonine,leucine,and isoleucine,increased polymyxin B1 production to 0.64 g/*** strains PPAC and ***-leu01 simultaneously inoculated into an optimized medium with 20 g/L peptone,polymyxin B1 production was increased to 0.97 g/***,the polymyxin B1 production in the co-culture of strains PPAC and ***-leu01 increased to 2.21 g/L after optimized inoculation ratios and fermentation medium with 60 g/L *** study provides a new strategy to improve polymyxin B1 production.

关键词： Polymyxin Co-culture Paenibacillus polymyxa Corynebacterium glutamicum Medium optimization Metabolic precursors