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Wave coupling between the Tianshan orogen and the deformations in its south and north foreland basins in Cenozoic

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Science China Earth Sciences 2008年第S2期51卷 61-69页

作者： chen shuping1,2,TANG LiangJie & YU YiXin1,2 1 State Key Laboratory of Petroleum Resource and Prospecting,China University of Petroleum,Beijing 102249,China 2 Department of Geoscience,China University of Petroleum,Beijing 102249,China State Key Laboratory of Petroleum Resource and Prospecting China University of Petroleum Beijing China Department of Geoscience China University of Petroleum Beijing China

Attention has been paid to the deformations in the south and north foreland basins of the Tianshan Mountains and their relations to the tectonic movements of the mountains. Based on the seismic data interpretation and field work,the tectonic features,tectonic styles,controlling factors of deformation,deformation time,and their relationships in the three tectonic units were comparably studied. The Ce-nozoic deformations in the two foreland basins were characterized by zonation from south to north,segmentation from west to east,and layering from deep to shallow. The tectonic styles are compres-sive ones,including both basement-involved and cover-detaching. The two foreland basins underwent several times of deformation in Cenozoic and the deformations were transmitted from the Tianshan orogen to the inner basin. The deformation dynamics of the south and north foreland basins of the Tianshan Mountains can be represented by dynamics of orogenic wedges. In terms of the deformations of the wedges with wave-like features,the concept of a wave orogenic wedge was put forward,and a double wave orogenic wedge model was established.

关键词： Tianshan orogen basin-mountain coupling tectonics wave orogenic wedge

Compositional and Hollow Engineering of Silicon Carbide/Carbon Microspheres as High-Performance Microwave Absorbing Materials with Good Environmental Tolerance

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Nano-Micro Letters 2024年第9期16卷 128-146页

作者： Lixue Gai Yahui Wang Pan Wan shuping Yu Yongzheng chen Xijiang Han Ping Xu Yunchen Du MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage School of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001People’s Republic of China Anhui Provincial Laboratory of Advanced Laser Technology College of Electronic EngineeringNational University of Defense TechnologyHefei 230037People’s Republic of China

Microwave absorbing materials(MAMs)characterized by high absorption efficiency and good environmental tolerance are highly desirable in practical *** silicon carbide and carbon are considered as stable MAMs under some rigorous conditions,while their composites still fail to produce satisfactory microwave absorption performance regardless of the improvements as compared with the ***,we have successfully implemented compositional and structural engineering to fabricate hollow Si C/C microspheres with controllable *** simultaneous modulation on dielectric properties and impedance matching can be easily achieved as the change in the composition of these *** formation of hollow structure not only favors lightweight feature,but also generates considerable contribution to microwave attenuation *** the synergistic effect of composition and structure,the optimized SiC/C composite exhibits excellent performance,whose the strongest reflection loss intensity and broadest effective absorption reach-60.8 dB and 5.1 GHz,respectively,and its microwave absorption properties are actually superior to those of most SiC/C composites in previous *** addition,the stability tests of microwave absorption capacity after exposure to harsh conditions and Radar Cross Section simulation data demonstrate that hollow SiC/C microspheres from compositional and structural optimization have a bright prospect in practical applications.

关键词： SiC/C composites Compositional engineering Hollow engineering Microwave absorption Environmental tolerance

Long-term thinning decreases the contribution of heterotrophic respiration to soil respiration in subalpine plantations

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Journal of Forestry Research 2024年第3期35卷 189-204页

作者： Longfei chen Zhibin He Wenzhi Zhao Xi Zhu Qin Shen Mingdan Song Zhengpeng Li Junqia Kong shuping Yang Yuan Gao Northwest Institute of Eco-Environment and Resources Chinese Academy of SciencesLanzhou 730000People's Republic of China State Forestry Administration Key Laboratory of Forest Resources and Environmental Management Beijing Forestry UniversityBeijing 100083People's Republic of China Academy of Agriculture and Forestry Sciences Qinghai UniversityXining 810000People's Republic of China College of Landscape Architecture Zhejiang A&F UniversityHangzhou 310000People's Republic of China

Interest in the dynamics of soil respiration(R_(S))in subalpine forest ecosystems is increasing due to their high soil carbon density and potential sensitivity to environmental ***,as a principal silvicultural practice,the long-term impacts of thinning on R_(S) and its heterotrophic and autotrophic respiration components(R_(h) and Ra,respectively)in subalpine plantations are poorly understood,espe-cially in winter.A 3-year field observation was carried out with consideration of winter CO_(2) efflux in middle-aged sub-alpine spruce plantations in northwestern China.A trench-ing method was used to explore the long-term impacts of thinning on Rs,Rn and R_(a).Seventeen years after thinning,mean annual Rs,Rn and R_(a) increased,while the contribu-tion of R_(h) to R_(s) decreased with thinning *** significantly decreased winter R,because of the reduction in R_(n) but had no significant effect on *** temperature sensitivity(Q_(10))of R_(h) and R_(a) also increased with thinning intensity,with lower Q_(10) values for R_(h)(2.1-2.6)than for Ra(2.4-2.8).The results revealed the explanatory variables and pathways related to R_(n) and R_(a) *** increased soil moisture and nitrate nitrogen(NO_(3)^(-)-N),and the enhanced nitrogen and water availability promoted R_(h) and R_(a) by improving fine root biomass and microbial *** results highlight the positive roles of NO_(3)^(-)-N in stimulating R_(s) components following long-term ***,applications of nitrogen fertilizer are not recommended while thinning subalpine spruce plantations from the perspective of reducing soil CO_(2) *** increased Q_(10) values of R_(s) components indicate that a large increase in soil CO_(2) emissions would be expected following thinning because of more pronounced climate warming in alpineregions.

关键词： Heterotrophic respiration Autotrophic respiration Long-term thinning impacts Cold seasons Subalpine plantations Temperature sensitivity

Electroacupuncture ameliorates blood-brain barrier disruption after ischemic stroke through histone acetylation regulation at the matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 2 genes

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Journal of Traditional Chinese Medicine 2024年第4期44卷 734-744页

作者： chen Yonglin OUYANG Ling MENG Lingling WU Bufan PENG Rou LIU Sitong HOU Dan WANG Yaling JING Xinyue LU Shengfeng FU shuping Key Laboratory of Acupuncture and Medicine Research of Ministry of Education Nanjing University of Chinese MedicineNanjing 210023China

OBJECTIVE:To explore whether the regulation of matrix metalloproteinase 9(MMP-9)/tissue inhibitors of MMPs(TIMPs)gene expression through histone acetylation is a possible mechanism by which electroacupuncture(EA)protects blood-brain barrier(BBB)integrity in a middle cerebral artery occlusion(MCAO)rat ***:Male Sprague-Dawley rats were divided into four groups:the sham group,the MCAO group,the MCAO+EA(MEA)group,and the MCAO+EA+HAT inhibitor(HATi)*** MCAO model was generated by blocking the middle cerebral *** was applied to Baihui(GV20).Samples were collected 1 or 3 d after *** function scores and Evans blue extravasation were employed to evaluate the poststroke *** effect of EA on MMP-9/TIMPs gene expression was assessed by real-time fluorescence quantitative polymerase chain reaction(RT-qPCR)and chromatin immunoprecipitation(ChIP).RESULTS:Our results showed that EA treatment prominently improved neurological function and ameliorated BBB *** RT-qPCR assay showed that EA reduced the expression of MMP-9 and promoted TIMP-2 mRNA expression,but HATi reversed these effects of *** addition,ChIP results revealed that EA decreased the enrichment of H3K9ace/H3K27ace at MMP-9 promoters and notably stimulated the recruitment of H3K9ace/H3K27ace at TIMP-2 ***:EA treatment at Baihui(GV20)regulates the transcription of MMP-9 and TIMP-2 through histone acetylation modification in the acute stage of stroke,which preserves the structural integrity of the BBB in MCAO *** findings suggested that the histone acetylation-mediated transcriptional activity of target genes may be a crucial mechanism of EA treatment in stroke.

关键词： blood-brain barrier matrix metalloproteinase 9 tissue inhibitor of metalloproteinases electroacupuncture histone acetylation

Underestimated benefits of NO_(x) control in reducing SNA and O_(3) based on missing heterogeneous HONO sources

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Frontiers of Environmental Science & Engineering 2024年第3期18卷 57-67页

作者： shuping Zhang Haotian Zheng Jun Liu Yao Shi Tianzeng chen Chaoyang Xue Fenfen Zhang Yueqi Jiang Xiangping Zhang Shovan Kumar Sahu Biwu Chu Jia Xing State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing 100084China China Academy of Civil Aviation Science and Technology Beijing 100028China State Key Joint Laboratory of Environment Simulation and Pollution Control Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China Yellow River Institute of Hydraulic Research Zhengzhou 450003China Centre for Climate Research Singapore Meteorological Service SingaporeSingapore 537054Singapore

Substantial NO_(x) emission mitigation is crucial for the synergistic reduction of particulate matter and ozone(O_(3))pollution in *** traditional air quality model does not consider heterogeneous HONO chemistry,leading to uncertainties in estimating the benefits of NO_(x) *** studies have shown that the parameterization of heterogeneous HONO formation increases both the simulated value of sulfate–nitrate–ammonium(SNA)and that of O_(3),thus adding the heterogeneous reactions of HONO into air quality models inevitably leads to changes in the estimated benefits of NO_(x) *** we investigated the changes in SNA and O_(3)concentrations from NO_(x) emission reduction before and after adding heterogeneous HONO reactions in the Community Multi-Scale Air Quality(CMAQ)*** heterogeneous HONO reactions in the simulation improved the benefits of NO_(x) reduction in terms of SNA control in *** 80%NO_(x) reduction,the reduction in SNA increased from 36.9%without considering heterogeneous HONO reactions to 42.8%with heterogeneous HONO *** reduction in the maximum daily 8h average(MDA8)O_(3)in summer caused by NO_(x) reduction increased slightly from 4.7%to 5.2%after adding heterogeneous HONO *** results in this study highlight the enhanced effectiveness of NO_(x) controls for the reduction of SNA and O_(3)after considering heterogeneous HONO formation in a complex chemical ambient,demonstrating the importance of NO_(x) controls in reducing PM2.5 and O_(3)pollution in China.

关键词： Heterogeneous HONO NO_(x) reduction PM_(2.5) O_(3)

Salted egg white derived-peptides VF-4 and DR-8 improve DSS-induced colitis in mice by inhibiting NF-κB/MAPK/PI3K-AKT signaling pathways and modulating gut microbiota composition

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Food Science and Human Wellness 2024年

作者： Na Zhou Na Wu Yao Yao shuping chen Mingsheng Xu Zhongping Yin Yan Zhao Yonggang Tu Jiangxi Key Laboratory of Natural Products and Functional Food， Jiangxi Agricultural University Agricultural Products Processing and Quality Control Engineering Laboratory of Jiangxi， Jiangxi Agricultural University Jiangxi Experimental Teaching Demonstration Center of Agricultural Products Storage and Processing Engineering， Jiangxi Agricultural University

Inflammation underlies many chronic diseases， and inflammatory bowel disease (IBD) is a condition characterized by long-term inflammation of the gut. Egg whites have been shown to contain many beneficial active substances. Therefore， we obtained two peptides from salted egg white: Val-Val-His-Phe (VF-4) and Asp-Thr-Gln-Ala-Met-Pro-Phe-Arg (DR-8). The sodium dextran sulfate (DSS)-induced mice colitis model was used to evaluate its regulatory effect on colitis in vivo. The results showed that VF-4 and DR-8 improved the clinical symptoms of DSS-induced colitis， attenuated colon tissue damage， inhibited the activation of NF-κB/MAPK/PI3K-AKT signaling pathways， and inhibited the expression of inflammatory cytokines. 16S rRNA gene sequencing showed that VF-4 and DR-8 administration increased the relative abundance of intestinal beneficial bacteria including Lactobacillus， Blautia， and down-regulated the relative abundance of inflammation-related bacteria including Acinetobacter， Lachnospiraceae＿NK4A136＿group， Klebsiella. Moreover， the degree of correlation between pro-inflammatory cytokines and microbiota was as follows: IL-6 > TNF-α > IL-1β > IFN-γ. In conclusion， this study suggests that salted egg white peptides VF-4 and DR-8 have a significant anti-inflammatory effect in vivo. It also provides a strategy for the treatment of inflammatory bowel disease and a new way for the high-value utilization of salted egg white.

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An Autonomously Hopping-off Micro Raised-flapping-wing Air Vehicle

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An Autonomously Hopping-off Micro Raised-flapping-wing Air V...

第三十一届中国控制会议

作者： GUO Jianglong~(1 a) Student Member IEEE chen shuping~(1 b) LI Long~1 YUAN Zhongqiu~1 WANG Yang~2 Student Member IEEE MA Mingxu~1. 1.School of Mechanical Engineering and Automation Northeastern University Shenyang 110819 2.Shenyang Institute of Automation Chinese Academy of Sciences 110016

＜正＞From the very prospective of bionic,the flight performance of a self-designed raised-wing outweighs its straight-wing is verified by utilizing the self-designed catapult and the control variable method in this *** on the status quo that the takeoff process of Micro Flapping-wing Air Vehicle（for short:FMAV） relies mostly on throwing,a Shape Memory Alloy（for short:SMA） actuated hopping mechanism and its germane control system attached appropriately on the FMAV are proposed and complemented,making it-An Autonomously Hopping-off Micro Raised-flapping-wing Air Vehicle（for short:AHRAV） take off and landing independently successfully,which will lessen FMAVs’ human interventions and increase their autonomous properties and enable them more applicable to future’s increasingly complicated conditions.

关键词： Biomc robot Micro Flapping-wing Air Vehicle hopping mechanism catapult Shape Memory Alloy

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数字全球价值链嵌入对城市碳排放绩效的影响

经济问题探索 2024年第4期 153-169页

作者：陈书平中共福建省委党校福州350108 厦门大学中国特色社会主义研究中心福建厦门361005

基于2012—2021年我国297个城市面板数据,选取面板固定效应模型与门槛模型,研究数字全球价值链嵌入对城市碳排放绩效的影响效应及作用机制。结果显示,数字全球价值链嵌入能够显著促进城市碳排放绩效提升,且该结论在经过一系列内生性与... 详细信息

基于2012—2021年我国297个城市面板数据,选取面板固定效应模型与门槛模型,研究数字全球价值链嵌入对城市碳排放绩效的影响效应及作用机制。结果显示,数字全球价值链嵌入能够显著促进城市碳排放绩效提升,且该结论在经过一系列内生性与稳健性检验后依然成立。机制研究结果表明,数字全球价值链嵌入能够通过绿色科技创新和绿色管理创新提高城市碳排放绩效。异质性检验结果显示,与东西部城市、资源型城市、低经济水平城市、低数字全球价值链嵌入水平城市及大城市相比,数字全球价值链嵌入对中部地区城市、非资源型城市、高经济水平城市、高数字全球价值链嵌入水平城市及中小城市碳排放绩效的正向促进效应更强。门槛效应结果表明,随着绿色管理创新水平提升,数字全球价值链嵌入对城市碳排放绩效的正向影响效应逐渐增强。基于此,提出科学布局数字全球价值链嵌入策略、因地制宜制定城市碳减排方针、着力提升城市绿色创新水平的政策建议,以期为推动碳排放绩效提升提供有效助益。

关键词：数字全球价值链嵌入城市碳排放绩效绿色创新碳排放强度碳排放效率

Tildrakizumab for moderate-to-severe plaque psoriasis in Chinese patients:A 12-week randomized placebo-controlled phase III trial with long-term extension

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Chinese Medical Journal 2024年第10期137卷 1190-1198页

作者： chen Yu Songmei Geng Bin Yang Yunhua Deng Fuqiu Li Xiaojing Kang Mingye Bi Furen Zhang Yi Zhao Weili Pan Zhongwei Tian Jinhua Xu Zhenghua Zhang Nan Yu Xinsuo Duan shuping Guo Qing Sun Weiquan Li Juan Tao Zhijun Liu Yuanyuan Yin Gang Wang Department of Dermatology Xijing HospitalThe Fourth Military Medical UniversityXi’anShaanxi 710032China Department of Dermatology The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi 710004China Department of Dermatology Dermatology Hospital of Southern Medical UniversityGuangzhouGuangdong 510091China Department of Dermatology Tongji HospitalHuazhong University of Science and TechnologyWuhanHubei 430030China Department of Dermatology The Second Hospital of Jilin UniversityChangchunJilin 130041China Department of Dermatology People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqiXinjiang 830001China Department of Dermatology Wuxi People’s Hospital of Wuxi CityWuxiJiangsu 214023China Department of Dermatology Shandong Provincial Hospital for Skin Diseases&Shandong Provincial Institute of Dermatology and VenereologyShandong First Medical University&Shandong Academy of Medical SciencesJinanShandong 250022China Department of Dermatology Beijing Tsinghua Changgung HospitalBeijing 102218China Department of Dermatology Zhejiang Provincial People’s HospitalHangzhouZhejiang 310014China Department of Dermatology The First Affiliated Hospital of Xinxiang Medical CollegeXinxiangHenan 453100China Department of Dermatology Huashan Hospital Affiliated to Fudan UniversityShanghai 200040China Department of Dermatology General Hospital of Ningxia Medical UniversityYinchuanNingxia 750000China Department of Dermatology Affiliated Hospital of Chengde Medical UniversityChengdeHebei 067000China Department of Dermatology The First Hospital of Shanxi Medical UniversityTaiyuanShanxi 030001China Department of Dermatology Qilu Hospital of Shandong UniversityJinanShandong 250012China Department of Dermatology Yuebei People’s HospitalShaoguanGuangdong 512026China Department of Dermatology Union Hospital Tongji Medical Collage Huazhong University of Science and TechnologyWuhanHubei 430022China Department of Dermatology and Venereal Diseases The First Affiliated Hospit

Background:There is a need for effective and safe therapies for psoriasis that provide sustained *** aim of this study was to assess the efficacy and safety of tildrakizumab,an anti-interleukin-23p19 monoclonal antibody,for treating moderate-to-severe plaque psoriasis in Chinese ***:In this multi-center,double-blind,phase III trial,patients with moderate-to-severe plaque psoriasis were enrolled and randomly assigned(1:1)to receive subcutaneous tildrakizumab 100 mg or placebo at weeks 0 and *** initially assigned to placebo were switched to receive tildrakizumab at weeks 12,16,and every 12 weeks *** in the tildrakizumab group continued with tildrakizumab at week 16,and every 12 weeks until week *** primary endpoint was the Psoriasis Area and Severity Index(PASI 75)response rate at week ***:At week 12,tildrakizumab demonstrated significantly higher PASI 75 response rates(66.4%[73/110]vs.12.7%[14/110];difference,51.4%[95%confidence interval(CI),40.72,62.13];P1)and Physician’s Global Assessment(60.9%[67/110]vs.10.0%[11/110];difference,49.1%[95%CI,38.64,59.62];P1)compared to *** 75 response continued to improve over time in both tildrakizumab and placebo-switching to tildrakizumab groups,reaching maximal efficacy after 28 weeks(86.8%[92/106]vs.82.4%[89/108])and maintained up to 52 weeks(91.3%[95/104]vs.87.4%[90/103]).Most treatment-emergent adverse events were mild and not related to ***:Tildrakizumab demonstrated durable efficacy through week 52 and was well tolerated in Chinese patients with moderate-to-severe plaque *** registration:***,NCT05108766.

关键词： Tildrakizumab Interleukin 23 Plaque psoriasis Chinese Randomized controlled trial