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Residual levels and health risk assessment of trace metals in Chinese resident diet

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Journal of Environmental Sciences 2024年第2期136卷 451-459页

作者： Yubing Dai shuai Sun Rong Cao Haijun Zhang Jiping chen Ningbo Geng CAS Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China Shenyang Pharmaceutical University Shenyang 110016China University of Chinese Academy of Sciences Beijing 100049China

Large-scale metal contamination across the food web is an intractable problem due to increasing pollutant emissions,atmospheric transport,and dry and wet deposition of elements.The present study focus on several trace metals that are rarely studied but have special toxicity,including tin(Sn),antimony(Sb),gold(Au),hafnium(Hf),palladium(Pd),platinum(Pt),ruthenium(Ru),tellurium(Te)and iridium(Ir).We investigated trace metals residues and distribution characteristics,and further evaluated the potential health risks from major daily food intakes in 33 cities in China.Sn,Sb,Ir,Hf,and Au were frequently detected in food samples with the concentrations ranged from ND(not detected)to 24.78μg/kg ww(wet weight).Eggs exhibited the highest residual level of all detected metals(13.70±14.70μg/kg ww in sum),while the lowest concentrations were observed in vegetables(0.53±0.17μg/kg ww in sum).Sn accounting for more than 50%of the total trace metals concentration in both terrestrial and aquatic animal origin foods.In terrestrial plant origin foods,Sn and Ir were the most abundant elements.Hf and Au were the most abundant elements in egg samples.In addition,Sb and Ir showed a clear trophic dilution effect in terrestrial environments,while in aquatic ecosystems,Sn,Hf,and Au exhibited obvious trophic amplification effects.The calculated average estimated daily intake(EDI)via food consumption in five regions of China was 0.09μg/(kg·day),implying the health risk of aforementioned elements was acceptable.

关键词： Trace metals Accumulation characteristics Dietary exposure Estimated daily intake(EDI)

A review on current development of thermophotovoltaic technology in heat recovery

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International Journal of Extreme Manufacturing 2024年第2期6卷 297-323页

作者： Shuni chen Yanming Guo Qinghui Pan Yong shuai Ministry of Industry and Information Technology Key Laboratory of Aerospace Thermophysics School of Energy Science and EngineeringHarbin Institute of TechnologyHarbin 150001People’s Republic of China

The burning of fossil fuels in industry results in significant carbon emissions,and the heat generated is often not fully utilized.For high-temperature industries,thermophotovoltaics(TPVs)is an effective method for waste heat recovery.This review covers two aspects of high-efficiency TPV systems and industrial waste heat applications.At the system level,representative results of TPV complete the systems,while selective emitters and photovoltaic cells in the last decade are compiled.The key points of components to improve the energy conversion efficiency are further analyzed,and the related micro/nano-fabrication methods are introduced.At the application level,the feasibility of TPV applications in high-temperature industries is shown from the world waste heat utilization situation.The potential of TPV in waste heat recovery and carbon neutrality is illustrated with the steel industry as an example.

关键词： thermophotovoltaic waste heat recovery micro/nano-fabrication carbon neutrality

Holocene Hydroclimatic Variations in the Asian Drylands:Current Understanding and Future Perspectives

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Journal of Earth Science 2024年第1期35卷 292-295页

作者： Guoqiang Ding Shengqian chen Yuanhao Sun shuai Ma Jianhui chen MOE Key Laboratory of West China's Environmental System College of Earth and Environmental SciencesLanzhou UniversityLanzhou 730000China Alpine Paleoecology and Human Adaptation Group State Key Laboratory of Tibetan Plateau Earth SystemEnvironment and ResourcesInstitute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China

0 INTRODUCTION.The intensification of global warming is generating increasing risks to human society and sustainable development,which are of growing concern to the international scientific community and policymakers(Sun,2023).The ecosystems of the Asian drylands are fragile and highly sensitive to global changes;moreover,while these drylands are the most important areas of oasis agriculture on Earth,their water resources are being adversely impacted by ongoing climate change(Zhang et al.,2023).Hence,an improved understanding of the patterns of climate change in this region is important and attracting increasing research attention.

关键词： Asian Holocene climatic

Spatio-Temporal Service Analysis in Multi-Layer Non-Terrestrial Networks

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Journal of Communications and Information Networks 2024年第1期9卷 43-55页

作者： Qian chen Weixiao Meng shuai Han cheng Li School of Electronics and Information Engineering Harbin Institute of TechnologyHarbin 150001China School of Engineering Science Simon Fraser UniversityBurnabyBC V5A 1S6Canada Department of Electrical and Computer Engineering Memorial UniversitySt.John’sNL A1B 3X5Canada

In the advent of the 6G era, non-terrestrial networks (NTN) with expansive coverage are being increasingly recognized as a vital supplement to cellular networks for facilitating seamless communication. The intricate interplay between network performance and service quality necessitates a thorough investigation into the modeling and analysis of services for efficient construction of NTN.Previous studies on service analysis, predominantly focused on terrestrial networks,fall short in addressing the unique challenges posed by NTN,particularly those related to platform distribution and antenna gain modeling. This deficiency in research,coupled with the varying preferences of users for different network types, forms the basis of this study. This paper explores the spatio-temporal characteristics of services within a multi-layered NTN framework.In this context,the spatial distribution of the platforms is modeled using a binomial point process, and the antennas are characterized by a sectorized beam pattern. We derive the closed-form expressions for the association probability,the number of accessed users, and the arrival rate of services with certain delay requirements towards different types of NTN. Simulation results are provided to evaluate the influence of various parameters on the association probability, the number of accessed users, and the total arrival rate of services. The number of satellites can be determined to achieve the optimal system utility,balancing the accessed services, offloading effects, and launching costs. This initial investigation lays the groundwork for further theoretical progress in the service analysis and platform deployment of NTN.

关键词： association strategy non-terrestrial networks service analysis stochastic geometry system utility

Global Phase Portraits of Uniform Isochronous Centers System of Degree Six with Polynomial Commutator

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Acta Mathematicae Applicatae Sinica 2024年第3期40卷 577-599页

作者： Li-na GUO Ai-yong chen shuai-feng ZHAO School of Mathematics and Statistics Henan University of Science and TechnologyLuoyang 471023China Department of Mathematics Hunan First Normal UniversityChangsha 410205China School of Mechatronics Engineering Henan University of Science and TechnologyLuoyang 471023China

This paper studies the global phase portraits of uniform isochronous centers system of degree six with polynomial commutator.Such systems have the form x=-y+xf(x,y),y=x+yf(x,y),where f(x,y)=a_(1)x+a_(2)xy+a_(3)xy^(2)+a_(4)xy^(3)+a_(5)xy^(4)=xσ(y),and any zero of 1+a_(1)y+a_(2)y^(2)+a_(3)y^(3)+a_(4)y^(4)+a_(5)y^(5),y=y is an invariant straight line.At last,all global phase portraits are drawn on the Poincare disk.

关键词： global phase portraits uniform isochronous center polynomial commutator invariant straight lines

Construction Activity Analysis of Workers Based on Human Posture Estimation Information

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Engineering 2024年第2期33卷 225-236页

作者： Xuhong Zhou shuai Li Jiepeng Liu Zhou Wu Yohchia Frank chen School of Civil Engineering Chongqing UniversityChongqing 400044China School of Automation Chongqing UniversityChongqing 400044China Department of Civil Engineering The Pennsylvania State UniversityMiddletownPA 17057USA

Identifying workers’construction activities or behaviors can enable managers to better monitor labor efficiency and construction progress.However,current activity analysis methods for construction workers rely solely on manual observations and recordings,which consumes considerable time and has high labor costs.Researchers have focused on monitoring on-site construction activities of workers.However,when multiple workers are working together,current research cannot accu rately and automatically identify the construction activity.This research proposes a deep learning framework for the automated analysis of the construction activities of multiple workers.In this framework,multiple deep neural network models are designed and used to complete worker key point extraction,worker tracking,and worker construction activity analysis.The designed framework was tested at an actual construction site,and activity recognition for multiple workers was performed,indicating the feasibility of the framework for the automated monitoring of work efficiency.

关键词： Pose estimation Activity analysis Object tracking Construction workers Automatic systems

Hepatic perivascular epithelioid cell tumors:The importance of preoperative diagnosis

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World Journal of Gastroenterology 2024年第13期30卷 1926-1933页

作者： shuai Yan Jia-Jie Lu Lin chen Wei-Hua Cai Jin-Zhu Wu Department of Medical School Nantong UniversityNantong 226300Jiangsu ProvinceChina Department of Hepatobiliary Surgery Affiliated Nantong Hospital 3 of Nantong UniversityNantong 226006Jiangsu ProvinceChina Nantong Institute of Liver Disease Affiliated Nantong Hospital 3 of Nantong UniversityNantong 226006Jiangsu ProvinceChina

Accurate preoperative diagnosis is highly important for the treatment of perivascular epithelioid cell tumors(PEComas)because PEComas are mainly benign tumors and may not require surgical intervention.By analyzing the causes,properties and clinical manifestations of PEComas,we summarize the challenges and solutions in the diagnosis of PEComas.

关键词： Hepatic perivascular epithelioid cell tumors Liver Preoperative diagnosis Angiomyolipomas Mesenchymal tissue-derived tumors

Biological factors driving colorectal cancer metastasis

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 259-272页

作者： shuai-Xing An Zhao-Jin Yu chen Fu Min-Jie Wei Long-Hai Shen Department of Pharmacology School of PharmacyChina Medical UniversityShenyang 110122Liaoning ProvinceChina Liaoning Key Laboratory of Molecular Targeted Antitumor Drug Development and Evaluation Liaoning Cancer Immune Peptide Drug Engineering Technology Research CenterKey Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors(China Medical University)Ministry of EducationShenyang 110122Liaoning ProvinceChina BD Department Greenpine Pharma Group Co.LtdTianjin 300020China Center of Oncology Genertec Liaoyou Gem Flower HospitalPanJin 124010Liaoning ProvinceChina

Approximately 20%of colorectal cancer(CRC)patients present with metastasis at diagnosis.Among Stage I-III CRC patients who undergo surgical resection,18%typically suffer from distal metastasis within the first three years following initial treatment.The median survival duration after the diagnosis of metastatic CRC(mCRC)is only 9 mo.mCRC is traditionally considered to be an advanced stage malignancy or is thought to be caused by incomplete resection of tumor tissue,allowing cancer cells to spread from primary to distant organs;however,increa-sing evidence suggests that the mCRC process can begin early in tumor development.CRC patients present with high heterogeneity and diverse cancer phenotypes that are classified on the basis of molecular and morphological alterations.Different genomic and nongenomic events can induce subclone diversity,which leads to cancer and metastasis.Throughout the course of mCRC,metastatic cascades are associated with invasive cancer cell migration through the circulatory system,extravasation,distal seeding,dormancy,and reactivation,with each step requiring specific molecular functions.However,cancer cells presenting neoantigens can be recognized and eliminated by the immune system.In this review,we explain the biological factors that drive CRC metastasis,namely,genomic instability,epigenetic instability,the metastatic cascade,the cancer-immunity cycle,and external lifestyle factors.Despite remarkable progress in CRC research,the role of molecular classification in therapeutic intervention remains unclear.This review shows the driving factors of mCRC which may help in identifying potential candidate biomarkers that can improve the diagnosis and early detection of mCRC cases.

关键词： cancer Metastasis cascade Cancer immunity Genomic variation Epigenetic instability Lifestyle factor

Hypomethylation of glycine dehydrogenase promoter in peripheral blood mononuclear cells is a new diagnostic marker of hepatitis B virus-associated hepatocellular carcinoma

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Hepatobiliary & Pancreatic Diseases International 2024年第1期23卷 35-42页

作者： Li-Li Miao Jing-Wen Wang Hui-Hui Liu shuai Gao Yu-chen Fan Kai Wang Department of Hepatology Qilu Hospital of Shandong UniversityJinan 250012China Experimental Center Shandong University of Traditional Chinese MedicineJinan 250355China Institute of Hepatology Shandong UniversityJinan 250012China

Background: Glycine dehydrogenase(GLDC) plays an important role in the initiation and proliferation of several human cancers. In this study, we aimed to detect the methylation status of GLDC promoter and its diagnostic value for hepatitis B virus-associated hepatocellular carcinoma(HBV-HCC). Methods: We enrolled 197 patients, 111 with HBV-HCC, 51 with chronic hepatitis B(CHB), and 35 healthy controls(HCs). The methylation status of GLDC promoter in peripheral mononuclear cells(PBMCs) was identified by methylation specific polymerase chain reaction(MSP). The mRNA expression was examined using real-time quantitative polymerase chain reaction(q PCR). Results: The methylation frequency of the GLDC promoter was significantly lower in HBV-HCC patients(27.0%) compared to that in CHB patients(68.6%) and HCs(74.3%)( P < 0.001). The methylated group had lower alanine aminotransferase level( P = 0.035) and lower rates of tumor node metastasis(TNM) Ⅲ/Ⅳ( P = 0.043) and T3/T4( P = 0.026). TNM stage was identified to be an independent factor for GLDC promoter methylation. GLDC mRNA levels in CHB patients and HCs were significantly lower than those in HBV-HCC patients( P = 0.022 and P < 0.001, respectively). GLDC mRNA levels were significantly higher in HBV-HCC patients with unmethylated GLDC promoters than those with methylated GLDC promoters( P = 0.003). The diagnostic accuracy of alpha-fetoprotein(AFP) combined with GLDC promoter methylation for HBV-HCC was improved compared with that of AFP alone(AUC: 0.782 vs. 0.630, P < 0.001). In addition, GLDC promoter methylation was an independent predictor for overall survival of HBV-HCC patients( P = 0.038). Conclusions: The methylation frequency of GLDC promoter was lower in PBMCs from HBV-HCC patients than that from patients with CHB and HCs. The combination of AFP and GLDC promoter hypomethylation significantly improved the diagnostic accuracy of HBV-HCC.

关键词： Hepatocellular carcinoma Glycine dehydrogenase DNA methylation Peripheral blood mononuclear cells