检索结果-南通市图书馆

Toxicity threshold of lead(Pb) to nitrifying microorganisms in soils determined by substrate-induced nitrification assay and prediction model

引用

Journal of Integrative Agriculture 2017年第8期16卷 1832-1840页

作者： ZHENG Han chen Li LI Ning LIU Bin MENG Nan WANG Meng chen shi-bao Key Laboratory of Plant Nutrition and Fertilizer Ministry of Agriculture/Institute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural Sciences Institute of Plant Protection and Environmental Protection Beijing Academy of Agriculture and Forestry Science

Lead （Pb） contamination has often been recorded in Chinese field soils. In recent years, efforts have been made to inves- tigate Pb toxicity thresholds in soils with plant growth and microbial assays. However, the influence of soil properties on Pb toxicity impacts on soil microbial processes is poorly understood. In this study ten soils with different properties were collected in China to investigate the relationships between thresholds of Pb toxicity to soil microbes and soil properties. The effect of soil leaching on Pb toxicity was also investigated to determine the possible influence of added anions on Pb toxicity during dose-response tests. Toxicity was inferred by measuring substrate-induced nitrification in leached and non-leached soils after Pb addition. We found that soil microbe Pb toxicity thresholds （ECx, x=10, 50） differed significantly between the soils; the 10% inhibition ratio values （ECI0） ranged from 86 to 218 mg kg-1 in non-leached soils and from 101 to 313 mg kg in leached soils. The 50% inhibition ratio values （EC50） ranged from 403 to 969 mg kg^-1 in non-leached soils and from 494 to 1 603 mg kg^-1 in leached soils. Soil leaching increased EC50 and EC50 values by an average leaching factor （LF） of 1.46 and 1.33, respectively. Stepwise multiple regression models predicting Pb toxicity to soil microbes were developed based on ECx and soil properties. Based on these models, soil pH and organic carbon are the most important soil properties af- fecting Pb toxicity thresholds （R2〉0.60）. The quantitative relationship between Pb toxicity and soil properties will be helpful for developing soil-specific guidance on Pb toxicity thresholds in Chinese field soils.

关键词： dose-response lead (Pb) polluted soil substrate-induced nitrification

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Overview on current criteria for heavy metals and its hint for the revision of soil environmental quality standards in China

引用

Journal of Integrative Agriculture 2018年第4期17卷 765-774页

作者： chen shi-bao WANG Meng LI Shan-shan ZHAO Zhong-qiu E Wen-di Key Laboratory of Plant Nutrition and Fertilizer Ministry of Agriculture/Institute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural Sciences School of Land Science and Technology China University of Geosciences National Agricultural Technology Extension and Service Center Ministry of Agriculture

Following rapid social and economic development over the past several decades, soil pollution by heavy metals(HMs) has been both serious and widespread in China. The Soil Environmental Quality Standards(SEQSs) in China(GB 15618-1995) have been introduced to encourage and enforce sustainable soil HM management. However, in recent years, HM contents in soils have frequently been found to exceed their associated standard values, while the crops growing on them might still meet regulatory standards, and vice versa. There is thus growing awareness that GB 15618-1995 does not effectively regulate current soil HM pollution, as it has encountered bottlenecks, and disappointing outcomes caused by poor execution along with deficiencies and gaps in the policies. However, due to the deficiency of scientific research about relationships between soil HM concentrations and their ecological or human health effects, the development of SEQSs in China is still greatly restricted. This paper discusses international SEQSs of HMs as well their development in China over time, then examines current Chinese SEQSs to demonstrate their potential regulatory deficiencies by referring to international SEQSs. The corresponding legislative policies are described, and scientific information or responses are outlined for maintaining soil environmental quality. China’s experience has shown that policy and science can be linked to work in tandem to better understand and manage soil quality issues.

关键词： soil heavy metals regulatory standards soil science policy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparison of phytotoxicity of copper and nickel in soils with different Chinese plant species

引用

Journal of Integrative Agriculture 2015年第6期14卷 1192-1201页

作者： LI Bo LIU Ji-fang YANG Jun-xing MA Yi-bing chen shi-bao Institute of Plant Nutrition and Environmental Resources Liaoning Academy of Agricultural Sciences National Soil Fertility and Fertilizer Effects Long-term Monitoring Network Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural Sciences Centre for Environmental Remediation Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences

Ecological risk assessment of metals in soils is important to develop the critical loads of metals in soils. Phytotoxicity is one of the endpoints for ecological risk assessment of soils contaminated with metals. The sensitivity of eight Chinese plant species（bok choy, mustard, tomato, green chilli, paddy rice, barley, spinach and celery） to copper（Cu） and nickel（Ni） toxicity in two Chinese soils was investigated to assess their potential use for ecological risk assessment in the region. The results showed that bok choy and mustard were the two most sensitive species to Cu and Ni toxicities. Assessment of metal accumulation by the plants demonstrated that bok choy shoot had the highest bioconcentration factor（BCF, the ratio of metal concentration in plant shoots to metal concentration in soil）. Given the importance of bok choy to agricultural production in Asia, it is therefore important that these sensitive plant species are included in species sensitivity distributions for ecological risk assessment of Cu and Ni in soils.

关键词： paddy shoot nickel tomato contaminated toxicity agricultural vegetative displayed ranged

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Variation of Cd concentration in various rice cultivars and derivation of cadmium toxicity thresholds for paddy soil by species-sensitivity distribution

引用

Journal of Integrative Agriculture 2015年第9期14卷 1845-1854页

作者： SONG Wen-en chen shi-bao LIU Ji-fang chen Li SONG Ning-ning LI Ning LIU Bin Key Laboratory of Plant Nutrition and Fertilizer Ministry of Agriculture/Institute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural Sciences Agricultural Information Institute Chinese Academy of Agricultural Sciences Institute of Plant Protection and Environmental Protection Beijing Academy of Agricultural and Forestry Science

It is imperative to derive an appropriate cadmium (Cd) health risk toxicity threshold for paddy soils to ensure the Cd con-centration of rice grains meet the food safety standard. In this study, 20 rice cultivars from the main rice producing areas in China were selected, and a pot-experiment was conducted to investigate transformation of Cd in paddy soil-rice system with 0 (CK), 0.3 mg kg–1 (T1) and 0.6 mg kg–1 (T2) Cd treatments in greenhouse. The results showed that Cd concentrations of rice grains existed signiifcant difference (P<0.05) in 20 rice cultivars under the same Cd level in soil. The Cd concentrations of rice grains of the CK, T1 and T2 treatments were in the range of 0.143–0.202, 0.128–0.458 and 0.332–0.806 mg kg–1, respectively. Marked differences of the ratios of Cd concentration for soil to rice grain (BCFs) and transfer factors (TFs, root to grain and straw to grain) among the tested cultivars were observed in this study. The bioconcentration factors (BCFgrain) and TFs of the 20 rice cultivars were 0.300–1.112 and 0.342–0.817, respectively. The TFs of Cd from straw to grain ranged from 0.366 to 1.71, with signiifcant differences among these 20 rice cultivars. The bioconcentration factors (BCFgrain) and TFs among the 20 rice cultivars ranged from 0.300–1.112 and 0.342–0.817, respectively. The species-sensitivity distribu-tion (SSD) of Cd sensitivity of the rice species could be iftted wel with Burr-III (R2=0.987) based on the data of BCFs. The toxicity threshold of Cd derived from SSD for the paddy soil was 0.507 mg kg–1 in the present study.

关键词： cadmium rice cultivars bioconcentration factor species-sensitivity distribution toxicity thresholds

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Subcellular Cd accumulation characteristic in root cell wall of rice cultivars with different sensitivities to Cd stress in soil

引用

Journal of Integrative Agriculture 2016年第9期15卷 2114-2122页

作者： LIU Bin chen Li chen shi-bao LI Ning ZHENG Han JIN Ke PANG Huan-cheng MA Yi-bing Key Laboratory of Plant Nutrition and Fertilizer Ministry of Agriculture/Institute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural Sciences Institute of Plant Protection and Environmental Protection Beijing Academy of Agricultural and Forestry Science

The variations of grain cadmiun（Cd） concentrations, translocation factors（TFs） of Cd from roots to shoots/grains of six rice cultivars, characterized with different Cd-sensitivities in polluted soil were studied, the selected rice cultivars were Xiangzao 17（R1）, Jiayu 211（R2）, Xiangzao 42（R3）, Zhuliangyou 312（R4）, Zhuliangyou 611（R5）, and Jinyou 463（R6）, respectively. The Cd subcellular distribution and Cd binding characteristics on subcellular fractions of rice root cell wall（CW） were further investigated. The results showed that the rice grain Cd contents varied significantly, with a maximum variation of 47.0% among the cultivars, the largest grain Cd content was observed with cultivar R1（Cd-sensitivity cultivar） and the smallest with R5（Cd-tolerance cultivar）. The translocation factors of Cd from roots to shoots（TF_（shoot）） and roots to grains（TF_（grain）） varied greatly among the cultivars. In general, the TFgrain of the cultivars followed the order of R1〉R2〉R3〉R4〉 R6-R5. The Cd concentration（mg kg^（–1） FW） in the fraction of root CW, the fraction of cell wall removing pectin（CW-P） and the fraction of cell wall removing pectin and hemicellulose（CW-P-HC） of the cultivars generally followed the order of CW-P〉CW〉CWP-HC; the ratios of Cd concentration（mg kg–1 FW） in the fraction of CW-P to that of CW were mostly more than 1.10, while the ratios of Cd concentration in the fraction of CW-P-HC to that of CW were mostly less than 0.60, indicating that Cd was mainly stored in the hemicellulose of the root CW. The ratios of Cd of CW-P-HC to CW generally followed the descending order of R1~R2〉R3〉R4〉R5~R6 for the cultivars, which implied that hemicellulose is probably the main subcellular pool for transferring Cd into rice grain, and it restrains the translocation of Cd from shoot to the grain, especially for the Cd-tolerance cultivars（R5 and R6）, the compartmentation of more Cd in hemicellulose in root CW is probably one of the main mechanisms for Cd tolerance of rice culti

关键词： cadmium rice cultivar(Oryza sativa) translocation factor subcellular distribution

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Inhibitory effects of idoxifene on hepatic fibrosis in rats

引用

Acta Pharmacologica Sinica 2005年第5期26卷 581-586页

作者： Ya-jun ZHOU~2,Dong-mei YIN,Hong-shan chen,Jian-hua shi,bao-xi SHA,Xing WANGDepartment of Biochemistry & Molecular Biology Medical College,Nan Tong University,Nantong 226001,China Department of Biochemistry & Molecular Biology Medical College Nan Tong University Nantong China

Aim:To investigate the effects of a tissue-specific selective estrogen receptormodulator,idoxifene,on hepatic fibrosis in ***:Hepatic fibrosis wasinduced by dimethylnitrosamine(DMN)in male *** DMN model of hepaticfibrosis and the hepatocytes undergoing oxidative stress were treated withidoxifene *** effect of idoxifene on hepatic fibrosis in the DMNmodel was examined by *** of idoxifene on antioxi-dant enzyme levels of copper,zinc-dependent superoxide dismutase(CuZn-SOD),and cellular glutathione peroxidase(GSHPx)were measured by *** ofidoxifene on activation,proliferation,and apoptosis of culture-activated hepaticstellate cells(HSC)were analysed by immunohistochemistry,bromodeoxyuridine(BrdU)uptake,and flow cytometry, respectively. Results:Idoxifene could mark-edly suppress DMN-induced hepatic fibrosis in male rats.A treatment of 0.4mg·kg-1·d-1of idoxifene reduced the protein levels of collagen in the DMN modelby 41.19%(P<0.05).Protein level of CuZn-SOD and activitiy of GSHPx in livertreated with DMN plus 0.4 ***-1·d-1of idoxifene were 2.65 times(P<0.05)and2.08 times greater(P<<0.05)than that of liver treated with DMN alone *** protein level of CuZn-SOD and activity of GSHPx in cultured rat hepatocytestreated with ferric nitrilotriacetate(FeNTA)plus 1×10-7mol/L of idoxifene were3.43 times(P<0.05)and 2.52 times(P<0.05)greater than that treated with *** could inhibit HSC *** with the control,theuptake of BrdU in HSC cultured with 1×10-7mol/L of idoxifene was reduced by51.87%(P<0.05),and the number of apoptotic HSCs cultured with 1×10-7mol/L ofidoxifene increased by 94.52%(P<0.05).Conclusion:Idoxifene showed inhibi-tory action on hepatic fibrosis in male rats.

关键词： fibrosis idoxifene oxidative stress hepatic stellate cell liver

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

An initial exploration of surgery following radiotherapy for the treatment of gliomatosis cerebri

引用

Chinese Medical Journal 2012年第24期125卷 4526-4527页

作者： WANG Jiang-fei JIANG Tao QIU Xiao-guang JIN Qiang chen bao-shi Department of Neurosurgery Beijing Yiantan Hospital Capital Medical University Beijing 100050 China Department of Radiotherapy Beijing Yiantan Hospital Capital Medical University Beijing 100050 China

Gliomatosis cerebri （GC） is a diffuse glial tumor that infiltrates the brain extensively. The optimaltherapeutic strategy for this tumor has not yet been established. Radiotherapy, temozolomide and other chemotherapeutic modalities have been used to treat GC.2 Despite aggressive and often multimodal therapeutic intervention, survival rates for adult and pediatric patients with GC are extremely poor. Here we report two cases of GC in which we initially explored a new therapeutic strategy for this disease.

关键词： gliomatosis cerebri radiotherapy surgery

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

不同草本植物间作对Cd污染土壤的修复效果

引用

中国环境科学 2018年第7期38卷 2618-2624页

作者：孟楠王萌陈莉郑涵陈世宝中国农业科学院农业资源与农业区划研究所农业部植物营养与肥料重点实验室北京100081 北京市农林科学院植物保护环境保护研究所北京100097

为了研究不同草本植物间作对空心菜Cd吸收效果及污染土壤中Cd移除率的影响,采用盆栽试验,以空心菜茎叶Cd消减率与土壤中Cd移除率为主要指标,研究了空心菜在Cd污染土壤中单作及与10种草本植物(高丹草,苏丹草,狼尾草,黑麦草,苦卖菜,菊苣,... 详细信息

为了研究不同草本植物间作对空心菜Cd吸收效果及污染土壤中Cd移除率的影响,采用盆栽试验,以空心菜茎叶Cd消减率与土壤中Cd移除率为主要指标,研究了空心菜在Cd污染土壤中单作及与10种草本植物(高丹草,苏丹草,狼尾草,黑麦草,苦卖菜,菊苣,籽粒苋,三叶草,紫花苜蓿,紫云英)间作的Cd积累效应与对Cd污染土壤的修复效果.结果表明:不同间作处理对空心菜茎叶与根中Cd含量有显著影响,其中,空心菜与高丹草、苏丹草、狼尾草间作后,空心菜茎叶Cd含量显著降低,空心菜茎叶Cd的消减率分别达到34.0%、35.8%、34.3%;菊苣、籽粒苋、三叶草、紫花苜蓿及紫云英与空心菜间作对空心菜茎叶Cd吸收有不同程度促进作用.间作的不同草本植物对土壤中Cd的吸收间有显著差异,地上部Cd含量范围1.81~12.87mg/kg,最大相差7.1倍;不同间作植物茎叶中Cd含量大小为:苦荬菜>菊苣>苏丹草≈黑麦草>高丹草≈狼尾草>紫花苜蓿≈籽粒苋>三叶草≈紫云英.不同草本植物与空心菜间作对土壤Cd移除率为0.35%~1.49%,其中,高丹草、苏丹草、狼尾草对土壤Cd的移除率分别达到1.46%、1.49%和1.48%;高丹草、苏丹草、狼尾草间作不仅可以有效降低空心菜Cd含量,同时对污染土壤中Cd具有较高的移除率,在Cd污染农田土壤的间作修复中具有较好的应用价值.

关键词：镉间作空心菜草本植物农艺修复

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

土壤中锌的形态转化、影响因素及有效性研究进展

引用

农业环境科学学报 2012年第2期31卷 221-229页

作者：林蕾陈世宝农业部作物营养与施肥重点开放实验室/中国农业科学院农业资源与农业区划研究所北京100081

土壤锌污染日益严重,锌产生的生物毒性越来越受到人们的关注,而锌在土壤中的生物毒性与其赋存形态密切相关。综述了近年来国内外土壤中锌生物毒性与锌形态研究的最新进展,其中包括土壤中锌的主要结合形态及其影响因素、锌的形态变化与... 详细信息

土壤锌污染日益严重,锌产生的生物毒性越来越受到人们的关注,而锌在土壤中的生物毒性与其赋存形态密切相关。综述了近年来国内外土壤中锌生物毒性与锌形态研究的最新进展,其中包括土壤中锌的主要结合形态及其影响因素、锌的形态变化与其生物有效性的关系、锌的形态分析技术最新发展趋势及土壤中锌毒性预测模型等。对土壤中锌的原位形态及未知形态的表征技术以及建立具有普适性的有效性测定方法将是未来研究的热点问题之一。

关键词：土壤污染锌形态分析生物有效性生态毒理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Antiangiogenic therapy with bevacizumab in recurrent malignant gliomas： analysis of the response and core pathway aberrations

引用

Chinese Medical Journal 2009年第11期122卷 1250-1254页

作者： ZHANG Wei QIU Xiao-guang chen bao-shi LI Shou-wei CUI Yun REN Huan JIANG Tao Department of Neurosurgery Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Department of Radiotherapy Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Department of Neuropathology Beijing Neurosurgical Institute Beijing 100050 China Department of Immunology College of Basic Medical Science Harbin Medical University Harbin 150086 China

Background Bevacizumab, a humanized monoclonal antibody against vascular endothelial growth factor, has shown promising activity in recurrent malignant gliomas. We reported the treatment response for the combination of bevacizumab and chemotherapy in a series of six patients with recurrent malignant glioma and investigated the molecular alterations in cancer pathways using the surgical biopsies from these patients. Methods Standard therapy with primary resection followed by adjuvant chemoradiotherapy had failed in all patients. Bevacizumab was administered at a dose of 10 mg/kg every 2 weeks. Concomitantly, four patients received temozolomide （50 mg·m^-2·d^-1）, one patient irinotecan （125 mg/m^2 every 2 weeks） and one patient topotecan （1.2 mg·m^-2·d^-1）. Response to therapy was mainly determined by magnetic resonance imaging. The expression of Ras, phosphorylated mitogen activated protein kinase （p-MAPK）, phosphorylated AKT （p-AKT）, phosphorylated mammalian target of rapamycin （p-mTOR） and phosphorylated signal transducer and activator of transcription 3 （p-STAT3） were semiquantitatively assessed by immunohistochemistry using surgical biopsies before the initial treatment. Results Five of the six patients had a radiographic response. Three were complete response, and two were partial response. Only one patient had progressive disease. The 6-month progession-free survival （PFS） was 33% and the median PFS was 15 weeks, with a range of 6 to more than 60 weeks. Of the three core pathways analyzed in this study, the Ras/MAPK and phosphatidylinositol-3-kinase （PI3K）/AKT/mTOR pathways were more likely to be associated with the treatment response to bevacizumab. In two younger patients （ages 〈50） with complete response, simultaneous overexpression of p-MAPK, p-AKT and p-mTOR might be the crucial feature. Conclusions Bevacizumab in combination with chemotherapeutic agents may be an effective strategy for patients with recurrent malignant glioma. Activated MAPK and AKT might

关键词： glioma molecularly targeted therapy bevacizumab antiangiogenic therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：