检索结果-南通市图书馆

CT-based radiomics to predict development of macrovascular invasion in hepatocellular carcinoma:A multicenter study

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2022年第4期21卷 325-333页

作者： Jing-Wei Wei Si-Rui Fu Jie Zhang Dong-Sheng Gu xiao-Qun li Xu-Dong cheng Shuai-Tong Zhang xiao-Fei He Jian-Feng Yan li-Gong Lu Jie Tian Key Laboratory of Molecular Imaging Institute of AutomationChinese Academy of SciencesBeijing 100190China Beijing Key Laboratory of Molecular Imaging Beijing 100190China university of Chinese Academy of Sciences Beijing 100049China Zhuhai Interventional Medical Center Zhuhai Precision Medical CenterZhuhai People’s HospitalZhuhai Hospital of Jinan UniversityZhuhai 519000China department of Radiology Zhuhai Precision Medical CenterZhuhai People’s HospitalZhuhai Hospital of Jinan UniversityZhuhai 519000China department of Interventional Treatment Zhongshan City People’s HospitalZhongshan 528400China department of Radiology Shenzhen People’s HospitalShenzhen 518000China Interventional Diagnosis and Treatment department Nanfang HospitalSouthern Medical UniversityGuangzhou510000China department of Radiology Yangjiang People’s HospitalYangjiang 529500China Beijing Advanced Innovation Center for Big Data-Based Precision Medicine School of Medicine and EngineeringBeihang UniversityBeijing 100191China engineering Research Center of Molecular and Neuro Imaging of Ministry of Education School of Life Science and TechnologyXidian UniversityXi’an 710126China

Background:Macrovascular invasion(MaVI)occurs in nearly half of hepatocellular carcinoma(HCC)patients at diagnosis or during follow-up,which causes severe disease deterioration,and limits the possibility of surgical *** study aimed to investigate whether computed tomography(CT)-based radiomics analysis could help predict development of MaVI in ***:A cohort of 226 patients diagnosed with HCC was enrolled from 5 hospitals with complete MaVI and prognosis ***-based radiomics signature was built via multi-strategy machine learning ***,MaVI-related clinical factors and radiomics signature were integrated to construct the final prediction model(CRIM,clinical-radiomics integrated model)via random forest ***-regression analysis was used to select independent risk factors to predict the time of MaVI ***-Meier analysis was conducted to stratify patients according to the time of MaVI development,progression-free survival(PFS),and overall survival(OS)based on the selected risk ***:The radiomics signature showed significant improvement for MaVI prediction compared with conventional clinical/radiological predictors(P1).CRIM could predict MaVI with satisfactory areas under the curve(AUC)of 0.986 and 0.979 in the training(n=154)and external validation(n=72)datasets,*** presented with excellent generalization with AUC of 0.956,1.000,and 1.000 in each external cohort that accepted disparate CT scanning protocol/***9_fos_InterquartileRange[hazard ratio(HR)=1.98;P1]was selected as the independent risk *** cox-regression model successfully stratified patients into the high-risk and low-risk groups regarding the time of MaVI development(P1),PFS(P1)and OS(P=0.002).Conclusions:The CT-based quantitative radiomics analysis could enable high accuracy prediction of subsequent MaVI development in HCC with prognostic implications.

关键词： Hepatocellular carcinoma Macrovascular invasion Radiomics Computed tomography Prognosis

Late Mesozoic rifting and its deep dynamic mechanisms in the central Sulu orogenic belt: Records from lingshan Island

在线全文

学校读者我要写书评

暂无评论

Science china Earth Sciences 2022年第9期65卷 1751-1771页

作者： Tengfei ZHOU Yaoqi ZHOU Nina SФAGER Paul Martin HOLM Zhenkai ZHANG Jun WANG Zhao liANG Hongyu MU Yanjun cheng Feifei liU Miao WANG Yue ZHANG Hui ZHANG Yangjian GU Shihui DONG Hanjie ZHAO Manjie li Yang chen Yanzi liU School of Geosciences China University of Petroleum(East China)Qingdao 266580China department of Geosciences and Natural Resource Management University of CopenhagenCopenhagen-K 1350Denmark Shandong Provincial Key Laboratory of Deep Oil&Gas China University of Petroleum(East China)Qingdao 266580China Shaanxi Center of Mineral Geological Survey Shaanxi Institute of Geological SurveyXi'an 710068China School of Earth Sciences Yunnan UniversityKunming 650500China department of Science and Technology Hebei GEO UniversityShijiazhuang 050031China College of Earth Science and engineering Shandong University of Science and TechnologyQingdao 266590China School of Architectural engineering Binzhou UniversityBinzhou 256500China Research Institute of Petroleum Exploration and Development Shengli Oilfield CompanySINOPECDongying 257015China Key Laboratory of Geological Safety of Coastal Urban Underground Space Ministry of Natural ResourcesQingdao Geo-Engineering Surveying InstituteQingdao 266101China

The lingshan Island scientific drill confirms that two episodes(Laiyang period and Qingshan period) of rifting developed in the central Sulu orogenic belt(SOB) in Late Mesozoic. With a set of methods including fieldwork, drilling, core logging, zircon U-Pb dating and whole rock geochemistry applied, the age, the depositional sequence and the deep dynamic mechanisms of rift evolution were unraveled. The stratigraphic sequence of the Laiyang-Qingshan Groups on lingshan Island was composed of two different rifting sequences:(1) Laiyang Group(147–125 Ma), which consists of deep-water gravity flow deposits with interlayers of intermediate volcanic rocks;and(2) Lower Qingshan Group(125–119 Ma), which unconformably overlies the former sequence and contains subaerial volcanic deposits and terrestrial deposits. The tectonic environment changed during the evolution of these two episodes of rifting: the rift was in a NNW-SSE extensional environment in the Laiyang period and showed the typical passive rifting character that “lithospheric extension and rifting preceded volcanism”. The passive rifting period was ended by a short WNW-ESE compression at about 125 Ma. After that, the tectonic environment transferred to a strong NW-SE extensional environment and the rifting evolved into a volcanic arc basin in the Qingshan period. The igneous rocks are shoshonitic to high-K calc-alkaline trachyandesites to trachytes with a few intercalated lamprophyres and a *** geochemical characteristics of the igneous rocks indicate that they are mantle-derived melts with a metasomatized mantle source and/or crustal contamination. In addition, an increased thinning of the lithosphere happened during the rifting *** low-angle subduction of the Paleo-Pacific plate in the Jurassic weakened the thickened SOB lithospheric mantle. The rollback of the subducting plate started in late Jurassic to early Cretaceous, and the SOB lithospheric mantle was delaminated synchronously because of t

关键词： Sulu orogenic belt lingshan Island Late Mesozoic Rifting Slab subduction Basin dynamics

Physical Activity,Sedentary Behavior,and the Risk of Cardiovascular Disease in Type 2 Diabetes Mellitus Patients:The MIDiab Study

在线全文

学校读者我要写书评

暂无评论

engineering 2023年第1期20卷 26-35页

作者： Yafei Wu Guijun Qin Guixia Wang libin liu Bing chen Qingbo Guan Zhongshang Yuan Xu Hou ling Gao Chao Xu Haiqing Zhang Xu Zhang Qiu li Yongfeng Song Fei Jing Shizhan Ma Shanshan Shao Meng Zhao Qingling Guo Nanwei Tong Hongyan Zhao xiaomin xie Chao liu Zhongyan Shan Zhifeng cheng Xuefeng Yu Shulin chen Tao Yang Yangang Wang Dongmei li Zhaoli Yan lixin Guo Qiuhe Ji Wenjuan Wang Jiajun Zhao department of Endocrinology&Shandong Clinical Research Center of Diabetes and Metabolic Diseases Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021China Shandong Key Laboratory of Endocrinology and lipid Metabolism&Shandong Prevention and Control engineering Laboratory of Endocrine and Metabolic Diseases Shandong First Medical UniversityJinan 250021China department of Endocrine and Metabolic Diseases The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China department of Endocrinology and Metabolism First Hospital of Jilin UniversityChangchun 130021China department of Endocrinology and Metabolism Fujian Medical University Union HospitalFuzhou 350001China Endocrinology department The Southwest Hospital of AMUChongqing 400038China department of Biostatistics School of Public HealthShandong UniversityJinan 250012China department of Endocrinology and Metabolism West China Hospital of Sichuan UniversityChengdu 610041China department of Endocrine and Metabolic Diseases Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200020China department of Endocrinology The First People’s Hospital of YinchuanYinchuan 750001China department of Endocrinology Nanjing Integrated Traditional Chinese and Western Medicine Hospital(the Affiliated Hospital of Nanjing University of Traditional Chinese Medicine)Nanjing 210046China department of Endocrinology and Metabolism&Institute of Endocrinology the First Hospital of China Medical UniversityShenyang 110000China department of Endocrinology the Fourth Affiliated Hospital of Harbin Medical UniversityHarbin 150001China Division of Endocrinology Department of Internal MedicineTongji HospitalTongji Medical College of Huazhong University of Science and TechnologyWuhan 430030China department of Endocrinology Yantai Yuhuangding Hospital Affiliated to Qingdao University Medical CollegeYantai 264000China department of Endocrinology the First Affiliated Hospital of Nanjing Medical University

The aim of this study was to explore the associations of moderate-to-vigorous-intensity physical activity(MVPA)time and sedentary(SED)time with a history of cardiovascular disease(CVD)and multifactorial(i.e.,blood pressure(BP),body mass index(BMI),low-density lipoprotein cholesterol(LDL-C),and glycated hemoglobin A1c(HbA1c))control status among type 2 diabetes mellitus(T2DM)patients in china.A cross-sectional analysis of 9152 people with type 2 diabetes from the Multifactorial Intervention on Type 2 Diabetes(MIDiab)study was *** were grouped according to their self-reported MVPA time(low,150 min·week−1;moderate,150 to1;high,≥450 min·week−1)and SED time(low,1;moderate,4 to1;high,≥8 h·d–1).Participants who self-reported a history of CVD were identified as having a CVD *** ratios(ORs)and 95%confidence intervals(CIs)of CVD risk and multifactorial control status associated with MVPA time and SED time were estimated using mixed-effect logistic regression models,adjusting for china’s geographical region *** participants had a mean±standard deviation(SD)age of(60.87±8.44)years,44.5%were women,and 25.1%had *** adjustment for potential confounding factors,an inverse association between high MVPA time and CVD risk that was independent of SED time was found,whereas this association was not observed in the moderate-MVPA group.A higher MVPA time was more likely to have a positive effect on the control of *** with the reference group(i.e.,those with MVPA time≥450 min·week−1 and SED time1),CVD risk was higher in the low-MVPA group:The OR associated with an SED time1 was 1.270(95%CI,1.040–1.553)and that associated with an SED time≥8 h·d–1 was 1.499(95%CI,1.149–1.955).We found that a high MVPA time(i.e.,≥450 min·week−1)was associated with lower odds of CVD risk regardless of SED time among patients with T2DM.

关键词： Type 2 diabetes Physical activity Sedentary time Car diovascular disease

Protected two-qubit entangling gate with mechanical driven continuous dynamical decoupling

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2022年第6期74卷 21-30页

作者： Xue-Jian Sun Wen-xiao liu Hao chen cheng-Yuan Wang Hui-Zhong Ma Hong-Rong li College of Physics and Telecommunication engineering Zhoukou Normal UniversityZhoukou 466001China department of Physics and Electronics North China University of Water Resources and Electric PowerZhengzhou 450046China College of Physics and Electronic Information engineering Qinghai Normal UniversityXining 810008China Institute of Quantum Optics and Quantum Information School of PhysicsXi'an Jiaotong UniversityXi'an 710049China

In this work, we propose a high-fidelity phonon-mediated entangling gate in a hybrid mechanical system based on two silicon-vacancy color centers in diamond. In order to suppress the influence of the spin decoherence on the entangling gate, we use a continuous dynamical decoupling approach to create new dressed spin states, which are less sensitive to environmental fluctuations and exhibit an extended T_(2)^(*) spin dephasing time. The effective spin-spin Hamiltonian modified by the mechanical driving field and the corresponding master equation are derived in the dispersive regime. We show that in the presence of the mechanical driving field, the effective spin-spin coupling can be highly controlled. By calculating the entangling gate fidelity in the dressed basis, we find that once the mechanical field is turned on, the gate fidelity can be significantly improved. In particular, under an optimized spin-phonon detuning and a stronger Rabi frequency of the mechanical driving field, the two-qubit gate is capable of reaching fidelity exceeding 0.99. Moreover, by employing appropriate driving modulation, we show that a highfidelity full quantum gate can be also realized, in which the initial and final spin states are on a bare basis. Our work provides a promising scheme for realizing high-fidelity quantum information processing.

关键词： silicon-vacancy color centers high-fidelity entangling gate mechanical driving modulation quantum information processing

青藏高原北羌塘地块下泥盆统平沙沟组古地磁学研究

在线全文

学校读者我要写书评

暂无评论

地球物理学进展 2024年第1期39卷 10-25页

作者：李腾程鑫周亚楠卫弼天幸龙云姜南陈庆龙王保锋许鹏祥张冬孟邓晓红兰书琪刘非凡王嘉伟武景岳吴汉宁西北大学地质学系/大陆动力学国家重点实验室西安710069 延安大学石油学院延安716000 甘肃煤炭地质勘查院兰州730000 甘肃煤田地质研究所兰州730000

泥盆纪时期各板块的古地理重建缺乏可靠古地磁数据,以至于古特提斯洋在泥盆纪的演化过程存在争议,而高质量的古地磁数据定量限定板块的古纬度位置是解决上述问题的关键.本文对北羌塘地块早泥盆世平沙沟组灰岩进行了古地磁学研究,提供了... 详细信息

泥盆纪时期各板块的古地理重建缺乏可靠古地磁数据,以至于古特提斯洋在泥盆纪的演化过程存在争议,而高质量的古地磁数据定量限定板块的古纬度位置是解决上述问题的关键.本文对北羌塘地块早泥盆世平沙沟组灰岩进行了古地磁学研究,提供了一个较为可靠的古地磁数据.镜下观察及岩石磁学实验结果表明平沙沟组灰岩样品中的主要载磁矿物为磁铁矿和赤铁矿,并且没有重磁化的特征.系统热退磁与混合退磁实验结果表明,样品的天然剩磁强度较低,从54块样品中获得了较为集中的特征剩磁分量,在样品水平下的平均方向为Dg=358.5°,Ig=22.8°,kg=17.7,α95=4.6°,Ds=8.8°,Is=-0.9°,ks=18.1,α95=4.5°,通过了C级倒转检验,对应的古地磁极为λp=54.8°N,φp=2.1.2°E,(dp/dm=2.3°/4.5°),这一极位置与石炭纪以来可靠的古地磁极位置存在差异,很可能代表了早泥盆世的原生剩磁方向.结合古生物学和地质证据,本文提出北羌塘地块早泥盆世位于古赤道附近(古纬度为0.5°S),此时北羌塘地块与华南板块位置接近,古特提斯洋可能已经存在.

关键词：古地磁北羌塘地块泥盆纪平沙沟组

基于导弹压力冲击平滑的燃气弹射装置环形腔结构参数次序优化

在线全文

学校读者我要写书评

暂无评论

推进技术 2019年第2期40卷 241-249页

作者：程洪杰陈力赵媛赵谢火箭军工程大学发射工程教研室陕西西安710025

针对导弹低燃温弹射压力双波峰冲击的问题,建立了含二次燃烧和尾罩运动的二维轴对称数值模型,在与实验数据对比的基础上验证了模型可靠性。研究了环形腔平滑弹底压力曲线的流场机理,解耦分析了其结构参数对压力冲击平滑效果的影响,并提... 详细信息

针对导弹低燃温弹射压力双波峰冲击的问题,建立了含二次燃烧和尾罩运动的二维轴对称数值模型,在与实验数据对比的基础上验证了模型可靠性。研究了环形腔平滑弹底压力曲线的流场机理,解耦分析了其结构参数对压力冲击平滑效果的影响,并提出了次序优化的思路。数值结果表明:环形腔能有效阻挡燃气向上扩散且腔内具有存储氧气的功能,使二次燃烧沿时间维度展开,从而平滑弹底压力冲击;在由初容室空间几何约束确立环形腔布置高度和环形半径后,以长度作为调控弹底压力曲线的主要结构参数,收缩或扩张角度作为微调的结构参数,可使压力曲线逼近理想设计曲线;布置优化后的环形腔,加速度峰值减小9.26%,出筒速度减小4.13%,出筒时间延长2.5%。

关键词：燃气弹射压力冲击环形腔内弹道流场载荷

在线全文

学校读者我要写书评

暂无评论

导弹燃气弹射内弹道多目标优化设计

推进技术 2018年第12期39卷 2651-2659页

作者：陈力程洪杰赵媛刘准火箭军工程大学发射工程系陕西西安710025

针对燃气弹射内弹道目标多导致传统穷举法寻优难的问题,在缩短初容段以提高车载机动性能的工况下,分析了环形隔板平滑弹底压力冲击、增大导流锥半径、减小筒底压力的流场机理,提出了第5块环形隔板和导流锥半径共同变化的结构方案;建立... 详细信息

针对燃气弹射内弹道目标多导致传统穷举法寻优难的问题,在缩短初容段以提高车载机动性能的工况下,分析了环形隔板平滑弹底压力冲击、增大导流锥半径、减小筒底压力的流场机理,提出了第5块环形隔板和导流锥半径共同变化的结构方案;建立了基于优化拉丁超立方和六阶响应面的近似数学模型,利用多岛遗传算法和序列二次规划算法搭建了组合优化策略平台。数值结果表明,提出的结构策略能平衡4个优化目标间耦合关系,搭建的优化平台能克服穷举寻优计算量大的局限,算法组合策略能互补优点而迅速捕捉最优解;优化后,加速度峰值减小了6.6%,加速度曲线平稳性增加了79.5%,筒底压力峰值增加了16.2%,弹底热环境品质增加了6.1%。

关键词：燃气弹射环形隔板导流锥试验设计近似数学模型组合优化设计

基于贝叶斯模型MixSIAR的不同水同位素输入方法对苹果园吸水特征分析结果的影响

在线全文

学校读者我要写书评

暂无评论

植物生态学报 2023年第2期47卷 238-248页

作者：路晨曦徐漫石学瑾赵成陶泽李敏司炳成西北农林科技大学旱区农业水土工程教育部重点实验室陕西杨凌712100 department of Soil Science University of SaskatchewanSaskatoon S7N5A8Canada

准确量化浅、中、深3层土壤水源对植物根系吸水的贡献是明确植物水分利用策略的前提。为探究同位素混合模型MixSIAR中不同水同位素输入方法对预估植物水分来源的影响,该研究于2.19年5-9月在陕西长武塬区对7年和18年苹果园共进行5次土壤... 详细信息

准确量化浅、中、深3层土壤水源对植物根系吸水的贡献是明确植物水分利用策略的前提。为探究同位素混合模型MixSIAR中不同水同位素输入方法对预估植物水分来源的影响,该研究于2.19年5-9月在陕西长武塬区对7年和18年苹果园共进行5次土壤和植物木质部取样,测定对应样品水同位素比值(δ2H、δ^(18)O)和土壤含水量,并分别利用基于单同位素(2H、^(18)O)、双同位素(2H&^(18)O)和经木质部氢同位素校正后双同位素(2H(+8.1)&^(18)O)输入的MixSIAR模型计算了根区不同土层(0-0.4、0.4-2、>2 m根系深度)土壤水对苹果(Malus pumila)树根系吸水的贡献率。结果表明:与2H单同位素方法相比,利用^(18)O单同位素方法得到的2 m以下深层土壤水的贡献率更低,而表层(0-0.4 m)土壤水的贡献率更高,且更接近于2H(+8.1)&^(18)O同位素方法。与2H&^(18)O双同位素方法相比,利用2H(+8.1)&^(18)O方法得到的表层土壤水的贡献率在表层土壤水同位素值富集时较高,在表层土壤水同位素值贫化时较低。苹果树木质部氢同位素校正后更靠近于土壤水同位素所在的蒸发线,因而相比于2H和2H&^(18)O,^(18)O和2H(+8.1)&^(18)O分析方法更符合根系吸水过程同位素质量守恒定律。与7年苹果园相比,18年苹果园浅层(0-2 m)土壤水的季节性变异更大,对表层土壤水的依赖更强。对于7年和18年苹果园,深层土壤水对其根系吸水贡献率的年平均值为19%和23%,两者无显著性差异。综上,建议今后在利用水稳定同位素研究植物水分来源时要进一步明确不同水同位素输入方法对植物水源划分分析结果的影响。

关键词：氢稳定同位素氧稳定同位素 MixSIAR 木质部氢同位素校正长武塬区苹果园

颞下颌关节疾病队列建立标准和质量控制专家共识(2024)

在线全文

学校读者我要写书评

暂无评论

中华口腔医学杂志 2024年第10期59卷 977-987页

作者：胡敏杨驰刘华蔚陆海霞姚晨谢秋菲陈永进傅开元房兵祝颂松周青陈志晔朱耀旻张清彬阎英龙星李志勇甘业华于世宾白玉兴张益王燕一雷杰程勇刘昌奎曹烨何冬梅温宁张善勇陈敏洁焦国良柳新华姜华贺洋沈佩黄海涛李永锋郑吉驷郭泾赵立升许来青解放军总医院口腔颌面外科北京100853 上海交通大学医学院附属第九人民医院口腔外科上海交通大学口腔医学院国家口腔医学中心国家口腔疾病临床医学研究中心上海市口腔医学重点实验室上海市口腔医学研究所上海200011 上海交通大学医学院附属第九人民医院口腔预防科上海交通大学口腔医学院国家口腔医学中心国家口腔疾病临床医学研究中心上海市口腔医学重点实验室上海市口腔医学研究所上海200011 北京大学第一医院口腔科北京100034 北京大学口腔医学院·口腔医院修复科国家口腔医学中心国家口腔疾病临床医学研究中心口腔生物材料和数字诊疗装备国家工程研究中心口腔数字医学北京市重点实验室北京100081 第四军医大学口腔医院急诊与综合临床科口颌系统重建与再生全国重点实验室国家口腔疾病临床医学研究中心陕西省口腔疾病国际联合研究中心西安710032 北京大学口腔医学院·口腔医院颞下颌关节病口颌面疼痛诊治中心国家口腔医学中心国家口腔疾病临床医学研究中心口腔生物材料和数字诊疗装备国家工程研究中心口腔数字医学北京市重点实验室北京100081 上海交通大学医学院附属第九人民医院正畸科上海交通大学口腔医学院国家口腔医学中心国家口腔疾病临床医学研究中心上海市口腔医学重点实验室上海市口腔医学研究所上海200011 四川大学华西口腔医院正颌及关节外科口腔疾病防治全国重点实验室国家口腔医学中心国家口腔疾病临床医学研究中心成都610041 中国医科大学口腔医学院·附属口腔医院口腔颌面外科辽宁省口腔疾病重点实验室沈阳110002 解放军总医院海南医院放射科三亚572013 深圳市口腔医院颌面外科医学中心深圳518055 广州医科大学附属口腔医院颞下颌关节科·广州口腔疾病研究所·口腔医学重点实验室广州510140 中山大学附属口腔医院口腔修复科·中山大学光华口腔医学院·广东省口腔医学重点实验室广州510055 武汉大学口腔医(学)院口腔颌面外科武汉430079 浙江大学医学院附属口腔医院口腔颌面外科·浙江大学口腔医学院浙江省口腔疾病临床医学研究中心浙江省口腔生物医学研究重点实验室浙江大学癌症研究院杭州310006 第四军医大学口腔医院颞下颌关节病科口颌系统重建与再生全国重点实验室国家口腔疾病临床医学研究中心陕西省口腔疾病国际联合研究中心西安710032 首都医科大学口腔医学院正畸科北京100050 北京大学口腔医学院·口腔医院口腔颌面外科国家口腔医学中心国家口腔疾病临床医学研究中心口腔生物材料和数字诊疗装备国家工程研究中心口腔数字医学北京市重点实验室北京100081 解放军总医院海南医院口腔科三亚572013 武汉大学口腔医(学)院放射科武汉430079 西安医学院口腔医学院口腔颌面外科西安710026 解放军联勤保障部队第980医院口腔中心石家庄050000 晋中市第一人民医院口腔颌面外科山西医科大学附属晋中医院山西省颞下颌关节疾病诊疗中心晋中030600 解放军总医院口腔修复科北京100853 大连医科大学附属第一医院口腔科大连116011 北京清华长庚医院口腔科北京102218 杭州医学院附属宁波口腔医院正畸科宁波315000

颞下颌关节(TMJ)疾病是临床常见疾病,患者数量众多,在病因、流行病学、疾病谱、治疗方式等方面尚存较多争议和未知。了解和掌握TMJ疾病发生发展和防治的现状,努力寻找病因、发病率、药物敏感性、预后等方面的规律,对于解决患者疾苦、深... 详细信息

颞下颌关节(TMJ)疾病是临床常见疾病,患者数量众多,在病因、流行病学、疾病谱、治疗方式等方面尚存较多争议和未知。了解和掌握TMJ疾病发生发展和防治的现状,努力寻找病因、发病率、药物敏感性、预后等方面的规律,对于解决患者疾苦、深入开展医学研究、有效预防疾病和制订相应的卫生政策等均有重要促进作用。队列建设及研究对疾病的精准预防、诊治水平提高有不可替代的作用,开展大规模人群队列研究有助于深入认识TMJ疾病的暴露、发病与转归情况。本共识旨在搭建TMJ疾病队列建立的标准概念框架,为制订TMJ疾病队列数据标准提供思路。共识提出TMJ疾病队列数据由通用数据标准和疾病特异数据标准两部分构成,其中通用数据标准针对各专病队列均有涉及,包含可以统一标准的问题或研究变量,便于在整合不同专病队列资源的同时,可以在相同的定义和标准下开展长期随访,以利于更好地收集核心数据和规范开展TMJ疾病队列研究。

关键词：颞下颌关节队列研究质量控制数据收集颞下颌关节疾病专家共识