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A Unified Time Scale Intelligent Control Algorithm for Microgrid Based on Extreme Dynamic Programming

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CSEE Journal of Power and Energy Systems 2020年第3期6卷 583-590页

作者： junbin chen Tao Yu Linfei Yin Jianlin Tang Hanqi Wang School of Electric Power South China University of TechnologyGuangzhou 510640China College of Electrical Engineering Guangxi UniversityNanning 530004China Department of Electronic Information and Electrical Engineering Dalian University of TechnologyDalian 116024China

Benefiting from the progress of power electronics technology,distributed generation technology is developing *** microgrids cannot rely on traditional multi-time scale control strategies to ensure the high-quality frequency stability control and economic dispatch in the same time scale,this paper proposes an extreme dynamic programming *** proposed algorithm takes an adaptive dynamic programming algorithm as the framework,an extreme learning machine as a kernel of the evaluation module,a model module,an implementation module and a new prediction *** resulting unified time scale intelligent control algorithm better realizes the combined functions of“droop control+automatic generation control+economic dispatch”in the traditional ***,in order to verify the effectiveness of the proposed algorithm,a microgrid model of 8 nodes is *** results confirm the feasibility and validity of the proposed extreme dynamic programming algorithm.

关键词： Extreme dynamic programming(EDP) microgrid frequency stability unified time scale

Factors Influencing Fracture Propagation in Collaborative Fracturing ofMultiple HorizontalWells

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Energy Engineering 2024年第2期121卷 425-437页

作者： Diguang Gong junbin chen cheng cheng Yuanyuan Kou Shanxi Key Laboratory of Well Stability and Fluid&RockMechanics inOil andGas Reservoirs Xi’an Shiyou UniversityXi’an710065China The Second Oil Production Plant Petro China Changqing Oilfield CompanyQingyang745100China

Horizontal well-stimulation is the key to unconventional resource exploration and *** development mode of the well plant helps increase the stimulated reservoir ***,fracture interference between wells reduces the fracturing ***,a 2D hydro-mechanical coupling model describing hydraulic fracture(HF)propagation is established with the extended finite element method,and the effects of several factors on HF propagation during multiple wells fracturing are *** results show that with an increase in elastic modulus,horizontal principal stress difference and injection fluid displacement,the total fracture area and the reservoir stimulation efficiency are both improved in all three fracturing *** a comparison of the three technologies,the method of improved zipper fracturing is proposed,which avoids mutual interference between HFs,and the reservoir stimulation effect is improved *** study provides guidance for optimizing the fracturing technology of multiple horizontal wells.

关键词： Multi-well fracturing inter-fracture interference hydraulic fracturing hydro-mechanical coupling extended finite element horizontal well

Efficacy and safety of a sequential treatment with clearing heat and eliminating phlegm and tonifying Qi and activating blood circulation in treating acute ischemic stroke: study protocol for a randomized controlled trial

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Journal of Traditional Chinese Medicine 2022年第4期42卷 604-610页

作者： ZHOU Ziyi WAN Can ZHAO Yuanqi LIU Xiangzhe GAO Ying AN Hongwei LI Lejun ZHANG Huili YU Xiaofei ZHANG Xinchun WANG Huijuan SHI Qing WEI Chunhua chen Jie HUANG Wenguo chen junbin GAO Ying HU Mingzhe CAI Yefeng Department of Neurology Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510120China the Second Clinical College of Guangzhou University of Chinese Medicine Guangzhou 510120China Department of Neurology The First Affiliated Hospital of Henan University of Traditional Chinese MedicineZhengzhou 450000China Department of Neurology Shenyang Second Hospital of Traditional Chinese MedicineShenyang 110100China Department of Neurology Liuzhou Traditional Chinese Medical HospitalLiuzhou 545001China Department of Neurology Wuxi Traditional Chinese Medicine HospitalWuxi 214071China Department of Neurology Qinhuangdao City Hospital of Traditional Chinese MedicineQinhuangdao 066000China Department of Neurology Shanghai Shuguang HospitalShanghai 200120China Department of Neurology the Second Hospital of Hebei Medical UniversityShijiazhuang 050000China Department of Neurology Jiangmen Wuyi Hospital of Traditional Chinese MedicineJiangmen 529000China Department of Neurology Nanshi Hospital Affiliated to Henan UniversityNanyang 473065China Department of Neurology Shanxi Province Hospital of Traditional Chinese MedicineXi'an 710003China Department of Neurology Maoming Hospital of Traditional Chinese MedicineMaoming 525000China Department of Neurology the Northern Guangdong People's HospitalShaoguan 512025China Department of Neurology and Stroke Center Dongzhimen Hospital affiliated to Beijing University of Chinese MedicineBeijing 100700China

OBJECTIVE:To investigate the short-term efficacy and safety outcomes following a sequential treatment with clearing heat and eliminating phlegm(CHEP)formula and tonifying Qi and activating blood circulation(TQABC)formula in patients with acute ischemic stroke(AIS)within a 72 h time ***:In this randomized,multicenter,doubleblinded,placebo-controlled trial,500 participants will be randomly assigned in a ratio of 1∶1 to the CHEP+TQABC group or control *** addition to guidelinebased standard medical care,participants in the treatment group will receive the CHEP formula for the first 5 consecutive days followed by the TQABC formula for another 10 consecutive days,while those in the control group will receive CHEP formula placebo and TQABC formula placebo *** primary outcome measure will be the comparison of the change in the National Institutes of Health Stroke Scale score from baseline to 15 days after *** secondary outcome measures will include the scores on the modified Rankin Scale,Barthel Index,Patient-Reported Outcomes,TCM symptom pattern(Zheng-hou)evaluation Scale,and the incidence of in-hospital *** assessment will include the physical examination,laboratory detection,any adverse events or serious adverse events,and the proportion of any complications during ***:The results of this study will provide objective and scientific data with which to assess the efficacy and safety of a sequential treatment based on“integrating disease and symptom pattern”for patients with AIS.

关键词： stroke clearing heat and eliminating phlegm tonifying Qi and activating blood circulation randomized controlled trial clinical protocols

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Noncationic polymer-assisted carrier for nucleic acid drug delivery

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Science China Materials 2024年第12期67卷 3796-3810页

作者： Miao Su junbin chen Yueqiang Zhu Chaoran chen Yuxi Zhang Xianzhu Yang School of Biomedical Sciences and Engineering South China University of TechnologyGuangzhou International CampusGuangzhou 511442China National Engineering Research Center for Tissue Restoration and Reconstruction South China University of TechnologyGuangzhou 510006China Guangdong Provincial Key Laboratory of Biomedical Engineering South China University of TechnologyGuangzhou 510006China

Nucleic acid drugs are emerging as a novel biotherapeutic modality for disease treatment,targeting nucleic acids to regulate the protein translation process and thereby facilitating disease *** hold significant promise in biomedical applications and treatment *** their negative charge,high molecular weight,and hydrophilic properties,nucleic acid drugs require carriers to traverse multiple biological barriers and facilitate intracellular *** material-based carriers present an unprecedented opportunity to address these challenges through electrostatic interactions with nucleic ***,concerns regarding the biosafety and cytotoxic responses of cationic materials have emerged in early clinical *** a result,the use of non-cationic polymer carriers,by controlling or circumventing the use of cationic materials,represents a promising approach for nucleic acid *** this review,we highlight various designs of non-cationic polymer carriers that go beyond the principle of electrostatic interactions,including conjugation,chemical bonding,physical crosslinking,hydrophobic interactions,and coordination bonding with nucleic ***,we discuss strategies for enhancing the efficiency of nucleic acid delivery and therapeutic effects of non-cationic polymer carriers,focusing on targeted delivery,cellular internalization,and endosomal escape.

关键词： nucleic-acid-based therapeutics nucleic acids delivery non-cationic polymer carriers

Natural Variation Identifies a Key Residue Required for a G-type Lectin Receptor Kinase-mediated Immune Complex Formation and Defense in Maize

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Natural Variation Identifies a Key Residue Required for a G-...

Natural variations of maize ZmLecRK1 determine its interaction with ZmBAK1 and resistance patterns to multiple pathogens

中国植物病理学会2024年学术年会

作者： LI Zhenju chen junbin ZHU Wangsheng State Key Laboratory of Maize Bio-breeding Key Laboratory of Surveillance and Management for Plant Quarantine PestsMinistry of Agriculture and Rural Affairsand College of Plant ProtectionChina Agricultural University

[Objective] Corn is an important staple crop in China and is a crucial feed and energy *** faches various pathogenic microorganisms throughout its growth cycle,leading to significant reductions in yield and *** three broad-spectrum resistance genes（ZmCCoAOMT2,ZmMM1,and ZmNANMT） have been *** study aims to identify new broad-spectrum resistance genes in corn by mapping maize inbred line populations.[Method] We analyzed the candidate genes on chromosome 5 in maize based on our previous whole_ genome association *** mechanisms of maize disease resistance genes were elucidated through genetic analysis,sequence diversity analysis,and biochemical analysis.[Result] We report the isolation and mechanistic characterization of a G-type Lectin receptor-like kinase encoding gene ZmLecRK that confers multi-pathogen resistance in *** interacts with its co-receptor,a leucine-rich repeat receptor-like kinase ZmBAK1-L1,and signals through the cytoplasmic receptor-like kinase ZmBLK1 for immune *** demonstrated that the A404 S mutation in the PAN domain of ZmLecRK is the major casual polymorphism that distinguishes the two functional different ZmLecRK proteins in maize inbred lines by modulating the ZmLecRK-ZmBAK1-L1 interaction and formation of ZmLecRK related protein *** analysis revealed that the susceptible LecRKs allele with S404 is highly conserved among the majority of LecRKs from grass species,but the resistant LecRKs allele with A404 is only present in half of maize inbred lines.[Conclusion] Taken together,we not only identified ZmLecRK as a new multi-pathogenresistant gene in maize but also pinpointed a key functional residue of ZmLecRK and its homologs in grass species,highlighting the possibility of precisely modulating the activity of ZmLecRK and its homologs for disease-resistant crops using targeted gene editing.

关键词： Maize Natural variation Multi-pathogen resistance Lectin receptor-like kinase

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Molecular Plant 2024年第10期17卷 1606-1623页

作者： Zhenju Li junbin chen Chuang Liu Shengfeng He Mingyu Wang Lei Wang Vijai Bhadauria Shiwei Wang Wenyu cheng Hui Liu Xiaohong Yang Mingliang Xu You-Liang Peng Wangsheng Zhu State Key Laboratory of Maize Bio-breeding/College of Plant Protection/Ministry of Agriculture and Rural Affairs Key Laboratory of Surveillance and Management for Plant Quarantine Pests China Agricultural UniversityBeijing 100193P.R.China Institute of Plant Protection and Microbiology Zhejiang Academy of Agricultural SciencesZhejiang 310021P.R.China Yazhouwan National Laboratory SanyaHainan 572024P.R.China Ministry of Agriculture and Rural Affairs Key Laboratory for Crop Pest Monitoring and Green Control College of Plant ProtectionChina Agricultural UniversityBeijing 100193P.R.China State Key Laboratory of Plant Environmental Resilience College of Agronomy and BiotechnologyNational Maize Improvement CenterCenter for Crop Functional Genomics and Molecular BreedingChina Agricultural UniversityBeijing 100193P.R.China

Maize(Zea mays)is one of the most important crops in the world,but its yield and quality are seriously affected by diverse *** broad-spectrum resistance genes is crucial for developing effective strategies to control the disease in *** a genome-wide study in maize,we identified a G-type lectin receptor kinase ZmLecRK1,as a new resistance protein against Pythium aphanidermatum,one of the causal pathogens of stalk rot in *** analysis showed that the specific ZmLecRK1 allele can confer resistance to multiple pathogens in *** cell death and disease resistance phenotype mediated by the resistant variant of ZmLecRK1 requires the co-receptor ZmBAK1.A naturally occurring A404S variant in the extracellular domain of ZmLecRK1 determines the ZmLecRK1-ZmBAK1 interaction and the formation of ZmLecRK1-related protein ***,the ZmLecRK1 susceptible variant was found to possess the amino acid S404 that is present in the ancestral variants of ZmLecRK1 and conserved among the majority of grass species,while the resistance variant of ZmLecRK1 with A404 is only present in a few maize inbred *** of S by A at position 404 in ZmLecRK1-like proteins of sorghum and rice greatly enhances their ability to induce cell *** transcriptomic analysis reveals that ZmLecRK1 likely regulates gene expression related to the pathways in cell wall organization or biogenesis in response to pathogen *** together,these results suggest that the ZmLecRK1 resistance variant enhances its binding affinity to the co-receptor ZmBAK1,thereby enhancing the formation of active complexes for defense in *** work highlights the biotechnological potential for generating disease-resistant crops by precisely modulating the activity of ZmLecRK1 and its homologs through targeted base editing.

关键词： natural variation G-type lectin receptor-like kinase co-receptor BAK1 broad-spectrum resistance genome-wide association study maize

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无监督动作迁移再修复的人脸重演方法

计算机工程与应用 2023年第19期59卷 192-200页

作者：陈俊彬杨志景广东工业大学信息工程学院广州510006

人脸重演可以将一个驱动人物的上半身动作迁移到目标人物上,合成一段视频。针对当前方法动作迁移不充分或合成的视频质量较低的问题,提出了无监督动作迁移再修复的人脸重演方法。利用一种无监督运动迁移模型,将驱动人物动作较为完整地... 详细信息

人脸重演可以将一个驱动人物的上半身动作迁移到目标人物上,合成一段视频。针对当前方法动作迁移不充分或合成的视频质量较低的问题,提出了无监督动作迁移再修复的人脸重演方法。利用一种无监督运动迁移模型,将驱动人物动作较为完整地迁移到目标人物,并得到粗糙的目标人脸视频。然后设计一个带有时空结构的生成神经网络,将粗糙的人脸视频修正为逼真流畅的人脸视频。为合成流畅且细节丰富的视频,在网络中引入了三维卷积以及注意力机制,更好地处理时空信息和指导图片的修正;为避免背景合成错误,将背景信息嵌入到网络作为固定参数;为提高牙齿的真实度,设计了一种嘴部增强损失。该网络以对抗的方式训练,确保了图片的真实感。实验结果表明,该算法可合成高质量的目标人物视频,性能指标优于目前先进的重演方法。

关键词：人脸重演无监督学习生成式对抗网络注意力机制三维卷积

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基于Heritrix的Web信息抽取

图书情报工作 2009年第9期53卷 112-115页

作者：陈俊彬曹树金中山大学资讯管理系广州510006

针对现阶段Web信息抽取技术的不足,提出一种基于Heritrix的精确抽取方法,由三个分别独立的功能模块共同完成。与一般信息抽取不同,本方法注重于在精确抽取的前提下实现通用化,做到可以根据数据库表的字段来进行最小单位的信息抽取,并且... 详细信息

针对现阶段Web信息抽取技术的不足,提出一种基于Heritrix的精确抽取方法,由三个分别独立的功能模块共同完成。与一般信息抽取不同,本方法注重于在精确抽取的前提下实现通用化,做到可以根据数据库表的字段来进行最小单位的信息抽取,并且较好地解决信息采集通用性和准确性之间的矛盾。

关键词： Heritrix 信息抽取 HTMLparser Web数据采集

CO_2对高密度水基钻井液性能影响规律及机理分析

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钻井液与完井液 2018年第5期35卷 26-30,35页

作者：向朝纲陈俊斌王龙川庆钻探工程有限公司钻采工程技术研究院四川广汉618300 川庆钻探工程有限公司国际工程公司成都610000

准确判断污染物浓度以及其对钻井液影响规律和内在机制是制定有效的CO_2污染防治措施的重要前提,基于酸碱指示变色原理,改进了钻井液中碱度现场定量检测方法,提高测量的准确性和可操作性;采用现场取样跟踪分析以及室内模拟评价相结合的... 详细信息

准确判断污染物浓度以及其对钻井液影响规律和内在机制是制定有效的CO_2污染防治措施的重要前提,基于酸碱指示变色原理,改进了钻井液中碱度现场定量检测方法,提高测量的准确性和可操作性;采用现场取样跟踪分析以及室内模拟评价相结合的方法,研究了CO_2对高密度水基钻井液流变性和滤失造壁性的影响规律,并从胶体化学的角度出发,开展了CO_2对钻井液黏土胶体颗粒界面Zeta电位、粒度分布以及处理剂吸附影响的实验研究,分析了其作用机理。研究表明,高密度水基钻井液中碳酸根和碳酸氢根存在临界污染浓度,超过此浓度后,钻井液结构黏度和滤失量随其浓度增加而增加;碳酸根和碳酸氢根离子改变了黏土颗粒溶剂化程度和颗粒尺寸,主要表现为黏土胶体颗粒界面电动电势降低、亚微米级粒子减少,粗颗粒增多,黏土颗粒对护胶剂的吸附量减少,导致高密度钻井液黏土颗粒向聚结方向转化并缔合形成三维网络结构的胶凝状态,揭示了宏观性能变化内在机制。

关键词：污染二氧化碳流变性能滤失性能高密度水基钻井液