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北京体育大学学报 2005年第5期28卷 703-705页

作者：陈洁敏绍兴文理学院体育学院浙江312000

运用三维运动解析系统,对我国部份男子铅球、标枪、铁饼运动员最后用力过程中右腿技术特征进行了运动学的比较分析,结果表明三个项目最后用力过程中右腿工作方式存在着较大的差异。

关键词：投掷右腿技术特征最后用力运动学

Electroretinogram and Histopathologic Changes of the Retina after Methanol Intoxication

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法医学杂志 2013年第1期29卷 5-11,16页

作者： chen jie-min ZHU Guang-you ZHAO Zi-qin XIA Wen-tao Shanghai Key Laboratory of Forensic Medicine Institute of Forensic Science Ministry of Justice P.R.China Shanghai 200063 China Department of Forensic Medicine Shanghai Medical College of Fudan University Shanghai 200032 China

In order to study the functional and structural alterations of the retina in SD rat model after methanol intoxication,35 rats were divided randomly into five groups administrated with saline,3-day high dose,7-day high dose,3-day low dose and 7-day low dose methanol *** retinal function of each group was assessed by flash electroretinogram(F-ERG) 3 and 7 days after methanol *** microstructure and ultrastructure of the retina were observed at the same *** high-dose methanol intoxication induced irreversible retinal functional and structural damages 3 days after poisoning,which included prolonged latency and reduced amplitude of the Max-reaction of *** injuries were aggravated 7 days after ***,the latency and amplitude of the Cone-reaction of F-ERG were also affected 3 days after poisoning,but there were no further worsening tendency 7 days after *** retinal histological analysis showed cellular edema,heteromorphy and disarrangement,tissular loosen of the inner nuclear layer and photoreceptors *** mitochondrial damage began at the photoreceptors layer and developed further into the inner nuclear *** low-dose methanol intoxication only caused transient damage of the *** results showed that the function and structure of the photoreceptor and inner nuclear layer were the primary target of methanol intoxication and that the rod cells were more sensitive to methanol intoxication than the cone *** mitochondrial damage developed from outer layer to inner layer of the retina.

关键词：甲醇中毒司法鉴定视网膜鉴定方法

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无缝线深板层角膜内皮移植术的研究进展

中华眼科杂志 2009年第10期45卷 952-956页

作者：陈敏洁龚岚复旦大学附属眼耳鼻喉科医院眼科上海200031

角膜内皮失代偿可严重影响视力，以往多采用的穿透性角膜移植手术（PKP）具有术后高度散光、移植片排斥等并发症，严重限制了术后视力的提高。如果能够单纯地进行后弹力层和内皮细胞层的移植，将减少手术操作所带来的受体角膜损伤并能... 详细信息

角膜内皮失代偿可严重影响视力，以往多采用的穿透性角膜移植手术（PKP）具有术后高度散光、移植片排斥等并发症，严重限制了术后视力的提高。如果能够单纯地进行后弹力层和内皮细胞层的移植，将减少手术操作所带来的受体角膜损伤并能更好地恢复术后视力。近年来，无缝线深板层角膜内皮移植手术的优点已逐渐获得公认；其中深板层角膜内皮细胞移植手术（DLEK）手术难度较大，限制了其在临床的广泛开展。而通过剥除受体角膜的后弹力层和内皮层来制作植床的角膜内皮移植手术即角膜后弹力层剥除内皮细胞移植手术（DSEK）已经取得了较好的手术效果。本文归纳、分析了DSEK的手术方法、效果及并发症等。

关键词：角膜移植内皮角膜

Synthesis,Structure　and　Properties　of　Inverse-Keggin　Potassium　Tetraniobooctatungstosilicate

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Chemical Research in Chinese Universities 1997年第3期13卷 195-200页

作者： YUE Bin, TANG Li-hao, RUI cheng-guo, LIU Hui-zhang, JIN Song-lin, ZHU Si-san (Department of Chemistry,Fudan University,Shanghai ,200433) LIU jie and chen min-qin (Center of Analysis and Measurement, Fudan Unive FUDAN UNIV DEPT CHEMSHANGHAI 200433PEOPLES R CHINA FUDAN UNIV CTR ANAL & MEASUREMENTSHANGHAI 200433PEOPLES R CHINA

Potassium tetraniobooccatungotosilicate, K8 [SiNb4 W8 O40] · 12H2 O was pre-pared by the reaction of white powdery tungstic acid, potassium niobate and potas -sium silicate in aqueous solution with pH value adjusted by potassium carbonate。The heteropolyniobotungstate crystallized in cubic space group Pm3m with unit cellparameters ;: a = 1.0640(1)nm,Z=1,V=1 .2045(5)nm3,R=0.055,Rw =0.062。The anion has inverse,Keggin structure,in which the central SiO4 tetrahedron isdistributed statistically in two orientations。The twelve outer metal positions arerandomly occupied by four niobium and eight tungsten atoms. Moreover, infraredspectrat electronic :spectra and thermogram were measured。

关键词： Tetraniobooctatungstosilicate Synthesis Inverse -Keggin structure

Role of iron ore in enhancing gasification of iron coke:Structural evolution,influence mechanism and kinetic analysis

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International Journal of minerals,Metallurgy and Materials 2025年第1期32卷 58-69页

作者： jie Wang Wei Wang Xuheng chen Junfang Bao Qiuyue Hao Heng Zheng Runsheng Xu School of Chemistry and Materials Science Hubei Engineering UniversityXiaogan 432000China Key Laboratory for Ferrous Metallurgy and Resources Utilization of ministry of Education Wuhan University of Science and TechnologyWuhan 430081China Institue of Ironmaking Technology Baosteel Central Research InstituteShanghai 201999China State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

The utilization of iron coke provides a green pathway for low-carbon *** uncover the influence mechanism of iron ore on the behavior and kinetics of iron coke gasification,the effect of iron ore on the microstructure of iron coke was ***,a comparative study of the gasification reactions between iron coke and coke was conducted through non-isothermal thermogravimetric *** findings indicate that compared to coke,iron coke exhibits an augmentation in micropores and specific surface area,and the micropores further extend and *** provides more adsorption sites for CO_(2) molecules during the gasification process,resulting in a reduction in the initial gasification temperature of iron *** the heating rate in non-isothermal gasification can enhance the reactivity of iron *** metallic iron reduced from iron ore is embedded in the carbon matrix,reducing the orderliness of the carbon structure,which is primarily responsible for the heightened reactivity of the carbon *** kinetic study indicates that the random pore model can effectively represent the gasification process of iron coke due to its rich pore ***,as the proportion of iron ore increases,the activation energy for the carbon gasification gradually decreases,from 246.2 kJ/mol for coke to 192.5 kJ/mol for iron coke 15wt%.

关键词： low-carbon ironmaking iron coke gasification structural evolution kinetic model

Increased excitatory amino acid transporter 2 levels in basolateral amygdala astrocytes mediate chronic stress–induced anxiety-like behavior

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Neural Regeneration Research 2025年第6期20卷 1721-1734页

作者： Xirong Xu Shoumin Xuan Shuai chen Dan Liu Qian Xiao jie Tu Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases Shenzhen-Hong Kong Institute of Brain ScienceShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina CAS Key Laboratory of Brain Connectome and Manipulation Brain Cognition and Brain Disease Institute(BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Brain Connectome and Behavior the Brain Cognition and Brain Disease Institute(BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina University of Chinese of Academy of Sciences BeijingChina Faculty of Life and Health Sciences Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina

The conventional perception of astrocytes as mere supportive cells within the brain has recently been called into question by empirical evidence, which has revealed their active involvement in regulating brain function and encoding behaviors associated with ***, astrocytes in the basolateral amygdala have been found to play a role in the modulation of anxiety-like behaviors triggered by chronic stress. Nevertheless, the precise molecular mechanisms by which basolateral amygdala astrocytes regulate chronic stress–induced anxiety-like behaviors remain to be fully elucidated. In this study, we found that in a mouse model of anxiety triggered by unpredictable chronic mild stress, the expression of excitatory amino acid transporter 2 was upregulated in the basolateral amygdala. Interestingly, our findings indicate that the targeted knockdown of excitatory amino acid transporter 2 specifically within the basolateral amygdala astrocytes was able to rescue the anxiety-like behavior in mice subjected to stress. Furthermore, we found that the overexpression of excitatory amino acid transporter 2 in the basolateral amygdala, whether achieved through intracranial administration of excitatory amino acid transporter 2agonists or through injection of excitatory amino acid transporter 2-overexpressing viruses with GfaABC1D promoters, evoked anxiety-like behavior in mice. Our single-nucleus RNA sequencing analysis further confirmed that chronic stress induced an upregulation of excitatory amino acid transporter 2 specifically in astrocytes in the basolateral amygdala. Moreover, through in vivo calcium signal recordings, we found that the frequency of calcium activity in the basolateral amygdala of mice subjected to chronic stress was higher compared with normal *** knocking down the expression of excitatory amino acid transporter 2 in the basolateral amygdala, the frequency of calcium activity was not significantly increased, and anxiety-like behavior was ob

关键词： anxiety astrocytes basolateral amygdala behavior dihydrokainic acid excitatory amino acid transporter 2 fiber photometry glutamate LDN-212320 transporter

Cyano migration-mediated radical-polar crossover cyclopropanation

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Science China Chemistry 2025年第01期 241-248页

作者： Ziqiang Wang Yasu chen jie Li chen Zhu Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry Chemical Engineering and Materials ScienceSoochow University Frontiers Science Center for Transformative Molecules Zhangjiang Institute for Advanced Study and Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs Shanghai Jiao Tong University

We report a novel cyano migration-mediated radical-polar crossover process, whereby both the sulfonylcyanation of aliphatic alkenes and the formation of cyclopropanes are concurrently achieved. This transformation yields a diverse array of multisubstituted cyclopropanes under mild photocatalytic conditions. Mechanistic studies elucidate that the reaction proceeds via intramolecular nucleophilic substitution, leading to the formation of the cyclopropane derivatives.

关键词：

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Ru doping triggering reconstruction of cobalt phosphide for coupling glycerol electrooxidation with seawater electrolysis

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Journal of Energy Chemistry 2025年第1期100卷 317-326页

作者： Binglu Deng jie Shen Jinxing Lu Chuqiang Huang Zhuoyuan chen Feng Peng Yunpeng Liu School of Materials Science and Hydrogen Energy Foshan University School of Chemistry and Chemical Engineering Guangzhou University Guangdong Key Laboratory for Hydrogen Energy Technologies

Seawater electrolysis is a promising approach for sustainable energy without relying on precious ***,the large-scale seawater electrolysis is hindered by low catalytic efficiency and severe anode corrosion caused by the harmful *** contrast to the oxygen evolution reaction （OER）and chlorin ion oxidation reaction （ClOR）,glycerol oxidation reaction （GOR） is more thermodynamically and kinetically favorable ***,a Ru doping cobalt phosphide （Ru-CoP2） is proposed as a robust bifunctional electrocatalyst for seawater electrolysis and GOR,for the concurrent productions of hydrogen and value-added *** in situ and ex situ characterization analyses demonstrated that Ru doping featured in the dynamic reconstruction process from Ru-CoP2to Ru-CoOOH,accounting for the superior GOR *** coupling GOR with hydrogen evolution was realized by employing Ru-CoP2as both anode and cathode,requiring only a low voltage of 1.43 V at 100 mA cm-2,which was 250 m V lower than that in alkaline *** work guides the design of bifunctional electrocatalysts for energy-efficient seawater electrolysis coupled with biomass resource upcycling.

关键词： Anodes

Dynamic behaviors of graphene platelets-reinforced metal foam piezoelectric beams with velocity feedback control

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 63-80页

作者： jie chen Xinyue ZHANG mingyang FAN School of Mathematics Statistics and Mechanics Beijing University of Technology College of Mechanical & Energy Engineering Beijing University of Technology

Graphene platelets(GPLs)-reinforced metal foam structures enhance the mechanical properties while maintaining the lightweight characteristics of metal foams. Further bonding piezoelectric actuator and sensor layers on the surfaces of GPLs-reinforced metal foam beams enables active vibration control, greatly expanding their applications in the aerospace industry. For the first time, this paper investigates the vibration characteristics and active vibration control of GPLs-reinforced metal foam beams with surfacebonded piezoelectric layers. The constant velocity feedback scheme is used to design the closed-loop controller including piezoelectric actuators and sensors. The effects of the GPLs on the linear and nonlinear free vibrations of the beams are numerically *** Newmark-β method combined with Newton's iteration technique is used to calculate the nonlinear responses of the beams under different load forms including harmonic loads,impact loads, and moving loads. Additionally, special attention is given to the vibration reduction performance of the velocity feedback control on the responses of the beam.

关键词： Piezoelectric actuators

维生素A棕榈酸酯对兔机械性角膜上皮损伤愈合及结膜杯状细胞的作用研究

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中华眼科杂志 2010年第2期46卷 151-160页

作者：邱晓頔龚岚陈敏洁复旦大学附属眼耳鼻喉科医院眼科上海200031

目的探讨维生素A棕榈酸酯与重组牛碱性成纤维细胞生长因子对兔机械性角膜上皮损伤愈合及结膜上皮细胞、杯状细胞的作用。方法实验研究。选取雄性新西兰大白兔120只，建立机械性角膜上皮损伤模型（角膜中央直径8mm上皮刮除），随机数字... 详细信息

目的探讨维生素A棕榈酸酯与重组牛碱性成纤维细胞生长因子对兔机械性角膜上皮损伤愈合及结膜上皮细胞、杯状细胞的作用。方法实验研究。选取雄性新西兰大白兔120只，建立机械性角膜上皮损伤模型（角膜中央直径8mm上皮刮除），随机数字表法分为4组，每组30只。A组使用盐酸林可霉素滴眼液，B组合用维生素A棕榈酸酯凝胶与盐酸林可霉素滴眼液，C组合用重组牛碱性成纤维细胞生长因子凝胶与盐酸林可霉素滴眼液，D组合用重组牛碱性成纤维细胞生长因子凝胶与维生素A棕榈酸酯凝胶及盐酸林可霉素滴眼液。各组均于机械性角膜上皮损伤建模后当日开始用药。用法均为3次／d，1滴／次，观察时间为7d。在模型建立第0、1、4、7天共4个时间点采用前节裂隙灯显微镜照相系统进行眼表照相，并计算角膜上皮损伤及其修复面积；在模型建立前及建立后第1、4、7天共4个时间点进行角结膜组织透射电镜检查、角膜光镜组织学检查及结膜印迹细胞学检查，对角膜上皮、结膜上皮细胞修复情况及结膜杯状细胞形态数量进行分析。采用方差分析、Tukey显著性检验等对数据进行统计学分析。结果造模后第1天各组角膜上皮已愈合面积比较差异有统计学意义（F=17．663，P=0．000），角膜上皮已愈合面积A组（53．512±18．850）mm^2，B组（92．194±14．367）mm^2，C组（89．779±20．535）mm^2，D组（127．816±16．379）mm^2，B组与C组之间差异无统计学意义（P=0．995）；结膜印迹细胞学检查显示，各组结膜杯状细胞数量（每740μm×550μm面积）明显下降，A组（10．083±4．441）个，B组（10．667±3．551）个，C组（9．583±4．502）个，D组（9．167±5．606）个，但各组之间的差异无统计学意义（F=0．239，P=0．868）。造模后第4天各组角膜上皮已愈合面积比较差异有统计学意义（F=37．665，P=0．000），角膜上皮已愈合面积A组（120．369±11．839）mm^2，B组（156．606±8．087）mm^2，C组（154．216±9．990）mm^2，D组（175．181±5．168）mm^2，B组与C组之间差异无统计学意义（P=0．968）；结膜印迹细胞学检查显示，各组结膜杯状细胞数量（每740μm×550μm面积）开始恢复，A组（41．250±4．575）个，B组（56．083±6．374）个，C组（48．417±4．562）个，D组（61．917±5．017）个，各组之间比较差异有统计学意义（F=36．210，P=0．000）。造模后第7天各组角膜上皮已愈合面积A组（177．472±3．585）mm^2，B组（186．715±3．022）mm^2，C组（182．293±3．158）mm^2，D组（194．106±2．176）mm^2，D组角膜上皮已愈合面积大于其他3组（P〈0．05）；结膜印迹细胞学检查显示，各组结膜杯状细胞数量（每740μm×550μm面积）明显恢复，A组（63．167±11．488）个，B组（99．501±15．877）个，C组（82．015±9．175）个，D组（104．750±9．659）个，各组之间比较差异有统计学意义（F=30．312，P=0．000），B组与D组之间比较差异无统计学意义（P=0．700）。透射电镜下观察角膜组织，维生素A棕榈酸酯和重组牛碱性成纤维细胞生长因子均能促进角膜上皮细胞之间连接的建立，维生素A棕榈酸酯具有保护角膜上皮细胞、防止上皮角化、促进角膜上皮增殖分化的作用。电镜检查结膜组织，可见B、D组新生的结膜杯状细胞数量较多，胞内分泌颗粒密集，与A、C组有明显差异，B、C、D组新生的结膜上皮细胞连接紧密。结论维生素A棕榈酸酯和重组牛碱性成纤维细胞生长因子均能够有效促进机械性角膜上皮损伤的角膜上皮修复，合并用药时作用最明显。维生素A棕榈酸酯可促进结膜杯状细胞的再生，促进结膜上皮细胞间连接的建立，明显优于重组牛碱性成纤维细胞生长因子。

关键词：上皮角膜伤口愈合杯状细胞维生素A 成纤维细胞生长因子2