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Stepped-up development of accelerator mass spectrometry method for the detection of ^(60)Fe with the HI-1. tandem accelerator

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Nuclear Science and Techniques 2024年第4期35卷 136-143页

作者： Yang Zhang Sheng-Quan Yan Ming He qing-Zhang Zhao Wen-Hui Zhang Chao-Xin Kan Jian-Ming Zhou Kang-Ning Li Xiao-Fei Wang Jian-{1.g {2. Zhao-Hua Peng Zhuo Liang Ai-Ling Li Jian Zheng Qi-Wen Fan Yun-Ju Li You-Bao Wang Zhi-Hong Li Yang-Ping Shen Ding Nan Wei Nan Yu-Qiang Zhang Jia-Ying-Hao Li Jun-Wen Tian Jiang-Lin Hou Chang-Xin Guo Zhi-{1.g Zhang Ming-Hao Zhu Yu-Wen {1. Yu-{1. Jiang Tao Tian Jin-Long Ma Yi-Hui {2. Jing-Yu Dong Run-Long {2. Mei-Yue-Nan Ma Yong-Shou {1. Wei-Ping {2. Bing Guo china {1. of Atomic Energy P.O.Box 275(10)Beijing 102413China College of Science Southern University of Science and TechnologyShenzhen 518055China School of Physics Xi’an Jiaotong UniversityXi’an 710049China

The Moon provides a unique environment for investigating nearby astrophysical events such as *** samples retain valuable information from these events,via detectable long-lived“fingerprint”radionuclides such as^(60)*** this work,we stepped up the development of an accelerator mass spectrometry(AMS)method for detecting^(60)Fe using the HI-1.tandem accelerator at the china {1. of Atomic Energy(CIAE).Since interferences could not be sufficiently removed solely with the existing magnetic systems of the tandem accelerator and the following Q3D magnetic spectrograph,a Wien filter with a maximum voltage of±60 kV and a maximum magnetic field of 0.3 T was installed after the accelerator magnetic systems to lower the detection background for the low abundance nuclide^(60)Fe.A 1.m thick Si_(3)N_(4) foil was installed in front of the Q3D as an energy *** particle detection,a multi-anode gas ionization chamber was mounted at the center of the focal plane of the ***,an^(60)Fe sample with an abundance of 1.1.2}×1.^(-1.)was used to test the new AMS *** results indicate that^(60)Fe can be clearly distinguished from the isobar^(60)*** sensitivity was assessed to be better than 4.3×1.^(-1.)based on blank sample measurements lasting 5.8 h,and the sensitivity could,in principle,be expected to be approximately 2.5×1.^(-1.)when the data were accumulated for 1.0 h,which is feasible for future lunar sample measurements because the main contaminants were sufficiently separated.

关键词： Accelerator mass spectrometry Wien filter Isobar separation Supernovae Chang'e-5 lunar samples

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The significance of lake sediments geochemistry in environmental reconstruction of south Hongshan Lake, northwestern Tibetan Plateau during the past 1.0 years

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Journal of Geographical sciences 2000年第3期10卷 65-71页

作者： chen Ling, ZHU Li-ping, ZHANG {1.-song ({2. of Geographic sciences and Natural Resources Research, chinese academy of sciences, Beijing 1.01.1. china)

A 1.7cm piston-core (SHC-2. was drilled at the site with water depth of 5m in South Hongshan Lake, northwest Tibet in 1.98. Based upon the 0.72.m/a of modern sedimentary rate that was tested by 2.0Pb method and also calibrated by 1.7Cs method as well as the 1.m interval sample cutting level, a lake sedimentary record of 1.0-yr old and with a resolution of 1.4 yrs was obtained. Ratio of geochemistry contents (TOC, TN, CaCO3) and concentrations of trace elements such as B, Sr, Ba, Ca, Mg, K, Na, Al, Ti, Cu, Zn, Fe, Mn, Ni, Cr, V, Pb, etc were analyzed. The values of TOC, TN, C/N, CaCO3, Sr/Ba and Fe/Mn had clear environmental significance and well reflected the environmental changes. Geochemical multi-proxies of lacustrine sediments from SHC-2.core showed that the environmental changes in this area during the past 1.0 years could be reconstructed as follows: Stage 1.(1.50s-1.80s) was a cold period; Stage 2.(1.80s-1.2.s) was a warm period. But the variation of lake water volume was stable in the two periods. Stage 3 (1.2.s-1.50s) was a fluctuant and transitional period in temperature, but there were a short cold period in the 1.2.s and a warm period in the 1.30s. Stage 4 (1.50s-) showed a warming tendency, though there existed a cold period from the mid 1.70s to the end of the 1.80s. In the view of general trend in the past 1.0 years, South Hongshan Lake was shrinking gradually. It showed that, from the comparison with the Guliya ice core and meteorological records of adjacent weather stations, there is difference in the variations of temperature and precipitation among different regions and altitudes in Tibetan Plateau. It is necessary to search multi-scale and high-resolution records for environmental reconstruction and comparison.

关键词： Kunlun Mts. south Hongshan Lake lake sediments geochemistry environmental changes

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枸杞脱毒苗的诱导及光合特性的分析研究

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四川大学学报（自然科学版） 2001年第4期38卷 550-553页

作者：曹有龙唐琳颜钫罗青郭宏玲陈放四川大学生命科学学院成都610064 宁夏农林科学院银川750001 宁夏林业厅银川750001

利用茎尖分生组织 (0 .2. 0 .4mm)培养和花药培养 ,获得了枸杞脱毒苗 .茎尖培养脱毒率在 72..7%～ 87.5 %之间 ,花药培养脱毒率在 70 .0 %～ 76 .5 %间 .进行 38℃下热处理茎尖分生组织组培苗 ,可提高脱毒效果 .叶绿素含量和光合强度... 详细信息

利用茎尖分生组织 (0 .2. 0 .4mm)培养和花药培养 ,获得了枸杞脱毒苗 .茎尖培养脱毒率在 72..7%～ 87.5 %之间 ,花药培养脱毒率在 70 .0 %～ 76 .5 %间 .进行 38℃下热处理茎尖分生组织组培苗 ,可提高脱毒效果 .叶绿素含量和光合强度测定表明 ,脱毒苗与对照相比 ,叶绿素含量增加 2..3～ 2.6 .9% ,光合强度增加 6 .9～ 1.0}.1.

关键词：枸杞脱病毒苗组织培养光合作用药用植物花药培养叶绿素

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Efficacy of hepatic arterial infusion chemotherapy and its combination strategies for advanced hepatocellular carcinoma:A network meta-analysis

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3672-3686页

作者： Shun-An Zhou qing-Mei Zhou Lei Wu Zhi-Hong {1. Fan Wu Zhen-Rong {1. Lian-Qun Xu Bi-LingGan Hao-Sheng Jin Ning Shi Department of General Surgery Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510000Guangdong ProvinceChina Department of Geriatrics Ganzhou Hospital-Nanfang HospitalSouthern Medical UniversityGanzhou 341000Jiangxi ProvinceChina Guangdong Cardiovascular institute Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510000Guangdong ProvinceChina Department of Liver Surgery Peking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100730China

BACKGROUND With the rapid progress of systematic therapy for hepatocellular carcinoma(HCC),therapeutic strategies combining hepatic arterial infusion chemotherapy(HAIC)with systematic therapy arised increasing ***,there have been no systematic review comparing HAIC and its combination strategies in the first-line treatment for advanced *** To investigate the efficacy and safety of HAIC and its combination therapies for advanced *** A network meta-analysis was performed by including 9 randomized controlled trails and 35 cohort studies to carry out our *** outcomes of interest comprised overall survival(OS),progression-free survival(PFS),tumor response and adverse *** ratios(HR)and odds ratios(OR)with a 95% confidence interval(CI)were calculated and agents were ranked based on their ranking *** HAIC outperformed Sorafenib(HR=0.55,95%CI:0.42.0.72.HR=0.51.95%CI:0.33-0.78;OR=2.86,95%CI:1.37-5.98;OR=5.45,95%CI:3.57-8.30;OR=7.1.,95%CI:4.06-1.0}58;OR=2.89,95%CI:1.99-4.1.;OR=0.48,95%CI:0.2.-0.92.respectively)and transarterial chemoembolization(TACE)(HR=0.50,95%CI:0.33-0.75;HR=0.62.95%CI:0.39-0.98;OR=3.08,95%CI:1.36-6.98;OR=2.07,95%CI:1.54-2.80;OR=3.1.,95%CI:1.71.5.85;OR=2.67,95%CI:1.59-4.50;OR=0.1.,95%CI:0.05-0.54,respectively)in terms of efficacy and ***+lenvatinib+ablation,HAIC+ablation,HAIC+anti-programmed cell death 1.PD-1.,and HAIC+radiotherapy had the higher likelihood of providing better OS and PFS outcomes compared to HAIC ***+TACE+S-1.HAIC+lenvatinib,HAIC+PD-1.HAIC+TACE,and HAIC+sorafenib had the higher likelihood of providing better partial response and objective response rate outcomes compared to ***+PD-1.HAIC+TACE+S-1.and HAIC+TACE had the higher likelihood of providing better complete response and disease control rate outcomes compared to HAIC *** HAIC proved more effective and safer than sorafenib and ***,combined with other interventions,HAIC showed imp

关键词： Hepatic arterial infusion chemotherapy Hepatocellular carcinoma Network meta-analysis Interventional therapy Systemic treatment

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A New Caffeate from the Aerial Parts of Anabasis aphylla

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chinese Herbal Medicines 2010年第4期2卷 248-249页

作者： LI Wei-lin1. 3, WANG Zhen-zhong2. WANG Hong-{1.1. GONG Ting1. chen Ruo-yun1.1. Key Laboratory of Bioactive Substances and Resources Utilization of {2. Herbal Medicine, Ministry of Education, institute of Materia Medica, {2. academy of Medical sciences and Peking Union Medical College, Beijing 1.0050, china 2. Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 2.2.01. china 3. Department of Pharmacology, Pharmacy College of Xinxiang Medical College, Xinxiang 453003, china Key Laboratory of Bioactive Substances and Resources Utilization of chinese Herbal Medicine Ministry of EducationInstitute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100050 China Department of Pharmacology Pharmacy College of Xinxiang Medical College Xinxiang 453003 China Jiangsu Kanion Pharmaceutical Co. Ltd. Lianyungang 222001 China Key Laboratory of Bioactive Substances and Resources Utilization of chinese Herbal Medicine Ministry of EducationInstitute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100050 China

Objective To study the chemical constituents from the aerial parts of Anabasis aphylla. Methods The chemical constituents were isolated and purified by silica gel column and Sephadex LH-2. column chromatography. Spectroscopic methods such as MS and NMR spectra were used for the structural identification. Results A new caffeate ester, named eicosyl-(Z)-caffeate (1., along with fourteen known compounds was isolated from the EtOAc part. Conclusion Compound 1.is a new compound and compounds 2.1. are isolated from the plants of Anabasis L. for the first time.

关键词： Anabasis L. Anabasis aphylla L eicosyl-(Z)-caffeate

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Advanced wastewater treatment with microalgae-indigenous bacterial interactions

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Environmental Science and Ecotechnology 2024年第4期20卷 198-207页

作者： Xue Li Shengnan Li Peng Xie Xi chen Yuhao Chu Haixing Chang Jian Sun {1. Li Nanqi Ren Shih-Hsin Ho State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin150090PR China College of Chemistry and Chemical Engineering Chongqing University of TechnologyChongqing400054PR China Central Southern china Municipal Engineering Design and Research {1. Co. LtdWuhan430010PR China

Microalgal-indigenous bacterial wastewater treatment(MBWT)emerges as a promising approach for the concurrent removal of nitrogen(N)and phosphorus(P).Despite its potential,the prevalent use of MBWT in batch systems limits its broader ***,the success of MBWT critically depends on the stable self-adaptation and synergistic interactions between microalgae and indigenous bacteria,yet the underlying biological mechanisms are not fully *** we explore the viability and microbial dynamics of a continuous flow microalgae-indigenous bacteria advanced wastewater treatment system(CFMBAWTS)in processing actual secondary effluent,with a focus on varying hydraulic retention times(HRTs).The research highlights a stable,mutually beneficial relationship between indigenous bacteria and *** and indigenous bacteria can create an optimal environment for each other by providing essential cofactors(like iron,vitamins,and indole-3-acetic acid),oxygen,dissolved organic matter,and *** collaboration leads to effective microbial growth,enhanced N and P removal,and energy *** study also uncovers crucial metabolic pathways,functional genes,and patterns of microbial ***,the effluent NH4 t-N and P levels complied with the chinese national Class-II,Class-V,Class-IA,and Class-IB wastewater discharge standards when the HRT was reduced from 1. to 6 *** results,including the highest rates of CO{1.fixation(1.{1. g L^(-1.),total energy yield(3{1.35 kJ L^(-1.),and the maximal lipid(33.91.)and carbohydrate(41.91.)content,were observed at an HRT of 1. ***,this study not only confirms the feasibility of CFMBAWTS but also lays a crucial foundation for enhancing our understanding of this technology and propelling its practical application in wastewater treatment plants.

关键词： Continuous flow systems Microalgal-indigenous bacterial interactions Advanced treatment Self-adaptation mechanisms Nutrient removal mechanisms

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Copper induced single electron transfer trifluorbmethylation of organic halides with 3-oxo-ω-fluorosulfonylperfluoropentyl iodide

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chinese Journal of Chemistry 1994年第5期12卷 464-467页

作者： DUAN, Jian-Xing chen, {1.-YunShanghai {2. of Organic Chemistry, chinese academy of sciences, 354 Fenglin Lu, Shanghai 2.0032. china

Treatment of ICF2.F2.CF2.F2.C2. (1. with organic halides in the presence of copper powder in a co-solvent DMF/HMPA( V/V= 1.1. gave the corresponding trifluoromethylated compounds in good to excellent yields. A copper ... 详细信息

关键词： Single electron transfer difluorocarbene trifluoromethylation trifluoromethylcop-per organic halides.

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从GDNF家族及其受体GFRα家族的进化分析中解析相互作用的功能决定位点

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生物化学与生物物理学报 2003年第4期35卷 331-337页

作者：张磬王丽梅陈哲宇丁达夫中国科学院上海生命科学研究院生物化学与细胞生物学研究所蛋白质组学重点实验室第二军医大学神经生物学教研室中国科学院上海生命科学研究院生物化学与细胞生物学研究所蛋白质组学重点实验室上海2.0031 上海2.0433

胶质细胞源神经营养因子 (glialcellline derivedneurotrophicfactor,GDNF)对神经退行性疾病具有潜在的治疗作用 ,因此解析GDNF及其糖基磷脂酰肌醇锚联受体GFRα的相互作用机制具有重要意义。根据蛋白质残基的功能重要性与自然选择压力... 详细信息

胶质细胞源神经营养因子 (glialcellline derivedneurotrophicfactor,GDNF)对神经退行性疾病具有潜在的治疗作用 ,因此解析GDNF及其糖基磷脂酰肌醇锚联受体GFRα的相互作用机制具有重要意义。根据蛋白质残基的功能重要性与自然选择压力相互关联的分子进化原理 ,对GDNF家族及其受体GFRα家族进行了进化踪迹分析 ,搜索到相互作用的功能决定位点。其中一些位点已被突变实验所证实 ,尤其大鼠GFRα1.功能位点N1.2.N1.3 ,R2.59、S3 1.N3 1.S3 1.和Q2.47D2.48S2.49经丙氨酸替换突变实验确认是GFRα1.GDNF或跨膜受体酪氨酸蛋白激酶Ret相结合的关键位点 ,在GDNF GFRα1.Ret复合体的形成中起到重要作用。

关键词：胶质细胞源神经营养因子家族(GDNF家族) GFRα家族 TGF-β超家族功能决定位点进化踪迹分析

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Some reactions of fluorosulfonyldifluoroacetic acid with N-heterocyclic compounds

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chinese Journal of Chemistry 1992年第4期10卷 350-354页

作者： chen,{1.-Yun YANG,Guo-Ying WU,Sheng-Wen Shanghai {2. of Organic Chemistry,chinese academy of sciences,Shanghai 2.0032 Shanghai institute of Organic Chemistry Chinese Academy of Sciences. Shanghai 200032

Difluorocarbene generated from the decomposition of fluorosulfonyldifluoroacetic acid (2. reacted with various sodium salts of N-heterocyclic compounds(1. giving the corresponding difluoro- methylated products in acetonitrile at 1.—40℃.Benzotriazole(1.),benzimidazole(1.) and imidazole (1.) were converted into 1.(difluoromethyl)benzotriazole(3a),1.(difluoromethyl)benzimidazole(3b) and 1.(difluoromethyl)imidazole(3c)***(1.)reacted with 2.to give -(fluorosulfonyldifluoro- acetate)indole(2.) rather than the expected difluoromethylated derivatives.

关键词： Some reactions of fluorosulfonyldifluoroacetic acid with N-heterocyclic compounds acid

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Cloning,identification and characterization of a repetitive sequence flanking telomere and homologous to canrep in Brassica napus

Cloning,identification and characterization of a repetitive ...

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湖北省遗传学会第八次代表大会暨学术讨论会

作者： chen Li~(1,2.,Xiaohong Yan~2.Jinyong Huang~3,Lijun Wang~2.qing Yang~(1,*),and Wenhui Wei~(2.*) 1 College of Life {2.,Nanjing Agricultural University,Nanjing 2.0095,china. 2.institute of Oil Crops,chinese academy of Agricultural {2.,Wuhan 430062.china 3 Department of Bioengineering,Zhengzhou University,Zhengzhou 450001,china.

Satellite DNAs consist of long tandem arrays of short repeated sequences that form the centromeric and sometimes also subtelomeric regions of all higher eukaryote *** and centromeres are the most important elements involved in the structure and function of chromosome. Telomeric DNA sequences are conserved among nearly all plant *** centromere-specific DNA sequences have been isolated in a wide range of plant species,almost no conservation was found in their DNA ***,the sequences were cloned from the subtelomeric regions of Brassica napus,through cloning the sequences flanking the telomeric repeats(TRs) of Brassica napus using cassette-ligation-mediated *** all the sequences were analyzed by BLAST approach of NCBI,a repetitive sequence was found to be highly homologous to canrep which is a centromeric satellite DNA sequence cloned in the previous *** revealed that this satellite was located primarily at centromeric regions of most chromosomes,and also at some chromosome *** the genomic DNAs of Brassica napus,*** and *** were analysed,the subtelomeric satellite DNA was found to be active in the evolution of chromosomes of Brassica *** tree analysis of this satellite showed it was conservative in *** reason why the centromeric satellites appear in the subtelomeric region is discussed.

关键词： Brassica napus subtelomere telomere-associated sequence(TAS) centromere satellite DNA

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