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Global precision analysis of carrier phase relative positioning in BeiDou navigation satellite system and United States global positioning system

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Science china {1. sciences 2019年第4期62卷 733-749页

作者： Letao ZHOU Dingfa huang Wei FENG {1. chen Xi ZHANG Li YAN department of Surveying and Geo-Informatics Faculty of Geosciences and Environmental EngineeringSouthWest JiaoTong University department of Land Surveying and Geo-Informatics Hong Kong Polytechnic University

In this paper, we derived a high-efficiency formula for calculating the precision of carrier phase relative positioning,analyzed the various factors that affect the positioning accuracy using the carrier phase, and proposed the concept of using a frequency dilution of precision to describe the quantitative effect of different frequency combinations on the positioning precision. To this end, we computed and plotted the global spatial distribution map of the relative positioning dilution of precision for single-day solution, half-hour solution, and single-epoch solution of the global positioning system(GPS), regional Beidou navigation satellite system(BDS2), future global Beidou navigation satellite system(BDS3., and their fusion *** processing software with autonomous intellectual property rights(GCN and VENUS/ARSNet), we solved the measurement data and examined the positioning precision of the single-day solution and single-epoch solution of GPS and *** analysis demonstrated that the B1.B2 frequency positioning precision of BDS2 was better than that of L1.L2 frequency positioning of GPS, but the positioning precision of the BDS2 is worse than that of GPS over most of the service region of the BDS2. Further, the positioning precision of BDS3.is better than that of GPS in the Asia-Pacific region, while it is the opposite in other regions. Based on these conclusions, we put forth some optimization recommendations regarding the signal frequency of the navigation system and GPS measurement standards to serve as references for optimizing the system performance and formulating standards.

关键词： BeiDou navigation satellite system Relative positioning Dilution of precision Frequency dilution of precision Spatial-temporal availability

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浙江省1.糖尿病住院患者临床特征及管理现状调查

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中华糖尿病杂志 2024年第1期16卷 56-62页

作者：陈琳娜曹星月符鸿俊黄海燕毛齐彬楼晓佳徐芬娟徐忠森沈晓明孙霞金剑虹武晓泓青岛大学医学部青岛266000 浙江省人民医院杭州医学院附属人民医院内分泌科杭州310014 浙江省台州恩泽医疗中心(集团)路桥医院内分泌科台州318050 浙江省杭州市富阳区中医院内分泌科杭州311400 绍兴第二医院内分泌科绍兴312000 浙江省东阳市人民医院内分泌科东阳322100 浙江省桐乡市第一人民医院内分泌科桐乡314500 浙江省衢州市柯城区人民医院内分泌科衢州324000 浙江省平湖市第一人民医院内分泌科平湖314200 浙江中医药大学附属丽水中医院内分泌科丽水323000 杭州市中医院内分泌科杭州310007

目的:探讨浙江省1.糖尿病(T1.M)住院患者的临床特征及管理现状。方法:为横断面研究。选择201.年1.月至2022年7月于浙江省1.家医院住院的T1.M患者作为研究对象。收集患者的一般临床资料(包括起病年龄、性别、住院天数、病程)、实验室指... 详细信息

目的:探讨浙江省1.糖尿病(T1.M)住院患者的临床特征及管理现状。方法:为横断面研究。选择201.年1.月至2022年7月于浙江省1.家医院住院的T1.M患者作为研究对象。收集患者的一般临床资料(包括起病年龄、性别、住院天数、病程)、实验室指标[包括生化、糖化血红蛋白、餐后2 h血糖、胰岛素、C肽、谷氨酸脱羧酶抗体(GADA)、蛋白酪氨酸磷酸酶抗体(IA-2A)、胰岛素自身抗体(IAA)、胰岛细胞抗体(ICA)]、并发症筛查情况(包括尿白蛋白/肌酐比值检测、眼底照相、肌电图、颈动脉超声、双下肢动脉超声及四肢多普勒超声)、治疗方案(包括胰岛素治疗方案及联用降糖药的情况)等。按照就诊时间将T1.M患者分为201.年1.月至201.年8月组及201.年9月至2022年7月组,比较两组慢性并发症筛查率、检出率及抗体检测率等情况。组间比较采用 χ2检验。结果:共564例T1.M患者纳入本研究。患者的年龄从1.到84岁不等,其中成人(≥1.岁)3.0例,儿童和青少年(1.岁)1.4例。T1.M患者的住院天数、起病年龄和病程中位数分别为7(6,1.)d、29(1.,45)岁和3.0,8)年。其中,56.6%(3.9/564)的T1.M患者有急性并发症,49.6%(280/564)的T1.M患者有慢性并发症。56.9%(3.1.564)的T1.M患者有合并症,包括血脂异常[25.7%(1.5/564)]、高血压[1..2%(69/564)]、高尿酸血症[8.2%(46/564)]、自身免疫性甲状腺疾病[9.0%(51.564)]、肥胖症[4.8%(27/564)]。糖尿病肾脏病、糖尿病视网膜病变、糖尿病周围神经病变及糖尿病周围血管病变的筛查率分别为71.5%(403.564)、58.9%(3.2/564)、55.5%(3.3.564)及80.7%(455/564),相应的检出率分别为21.6%(87/403.、27.4%(91.3.2)、47.0%(1.7/3.3.和3..6%(1.4/455)。99.5%(561.564)的T1.M患者使用胰岛素治疗。每日多次胰岛素注射治疗占比最高,为78.7%(444/564)。除胰岛素外,3..0%(1.2/564)的T1.M患者还联用非胰岛素类药物,α-葡萄糖苷酶抑制剂是最常用的药物[53.6%(1.3.1.2)]。201.年9月至2022年7月组GADA、IA-2A、ICA、IAA检测率高于201.年1.月至201.年8月组( P201.年9月至2022年7月组患者慢性并发症筛查率均比201.年1.月至201.年8月组高,包括视网膜病变、周围神经病变、周围血管病变筛查率均提高( P1.M患者主要是成人起病。近年来,浙江省T1.M患者的糖尿病并发症筛查率及抗体检测率呈上升趋势,体现了浙江省对T1.M住院患者的管理较前更加规范,但糖尿病抗体检测率及并发症的筛查率仍较低,有待进一步提高。

关键词：糖尿病 1. 管理筛查

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Intracellular codelivery of anti-inflammatory drug and anti-miR 1.5 to treat inflammatory disease

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Acta Pharmaceutica Sinica B 2020年第8期10卷 1521-1533页

作者： Chao Teng chenshi Lin Feifei {1. xuyang Xing Shenyu chen Ling Ye Helena S.Azevedo chenjie xu Zhengfeng wu Zhongjian chen Wei He School of Pharmacy China Pharmaceutical UniversityNanjing 210009China School of Pharmaceutical sciences Southern Medical UniversityGuangzhou 510515China School of Engineering and Materials Science Institute of BioengineeringUniversity of LondonLondon E14NSUK department of Biomedical Engineering City University of Hong KongKowloonHong KongChina Key Laboratory of Modern Preparation of TCM Ministry of EducationJiangxi University of Traditional Chinese MedicineNanchang 330004China Shanghai Skin Disease Hospital Tongji University School of MedicineShanghai 200443China

Atherosclerosis(AS) is a lipid-driven chronic inflammatory disease occurring at the arterial subendothelial space. Macrophages play a critical role in the initiation and development of AS. Herein,targeted codelivery of anti-miR 1.5 and anti-inflammatory baicalein is exploited to polarize macrophages toward M2 phenotype, inhibit inflammation and treat AS. The codelivery system consists of a carrier-free strategy(drug-delivering-drug, DDD), fabricated by loading anti-miR1.5 on baicalein nanocrystals,named as baicalein nanorods(BNRs), followed by sialic acid coating to target macrophages. The codelivery system, with a diameter of 1.0 nm, enables efficient intracellular delivery of anti-miR1.5 and polarizes M1.to M2, while markedly lowers the level of inflammatory factors in vitro and in vivo. In particular, intracellular fate assay reveals that the codelivery system allows for sustained drug release over time after internalization. Moreover, due to prolonged blood circulation and improved accumulation at the AS plaque, the codelivery system significantly alleviates AS in animal model by increasing the artery lumen diameter, reducing blood pressure, promoting M2 polarization, inhibiting secretion of inflammatory factors and decreasing blood lipids. Taken together, the codelivery could potentially be used to treat vascular inflammation.

关键词： miR1.5 inflammatory sustained

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Deep learning projects future warming-induced vegetation growth changes under SSP scenarios

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Advances in Climate Change Research 2022年第2期13卷 251-257页

作者： Zhi-Ting chen Hong-Yan LIU Chong-Yang {1. Xiu-chen wu Bo-Yi LIANG Jing CAO Deliang chen College of Urban and Environmental sciences and MOE Laboratory for {1. Surface Processes Peking UniversityBeijing 100871China Faculty of Geographical sciences Beijing Normal UniversityBeijing 100875China department of {1. sciences University of GothenburgGothenburg 40530Sweden

Climate warming has been projected to enhance vegetation growth more strongly in higher latitudes than in lower latitudes,but different projections show distinct regional *** employing big data analysis(deep learning),we established gridded,global-scale,climate-driven vegetation growth models to project future changes in vegetation growth under SSP *** projected no substantial trends of vegetation growth change under the sustainable development scenario(SSP1.1.9)by the end of the 21.t ***,the increase of vegetation growth driven by climate warming shows distinct regional variability under the scenario representing high carbon emissions and severe warming(SSP5-8.5),especially in Northeast Asia where growth could increase by(6.00%±4.21.).This may be attributed to the high temperature sensitivities of the deciduous needleleaf forests and permanent wetlands in these *** the temperature sensitivity that is defined as permutation importance in deep learning is greater than 0.05,the increase in vegetation growth will be more *** addition,an extreme temperature increase across grasslands,as well as changing land-use management in northern china may also influence the vegetation growth in the *** results suggest that the sustainable development scenario can maintain stable vegetation growth,and it may be a reliable way to mitigate global warming due to potential climate feedbacks driven by vegetation changes in boreal *** needleleaf forests will be a centre of greening in the future,and it should become the focus of future vegetation dynamics modelling studies and projections.

关键词： Vegetation growth Climate change Deep learning Climate sensitivity Future projection

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earth-abundant photovoltaic semiconductor NaSbS2 in the rocksalt-derived structure:A first-principles study

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Progress in Natural Science:Materials International 2019年第3期29卷 322-328页

作者： Xian Zhang Menglin huang Peng {1. chen-Min Dai Zenghua Cai Dan Han Shiyou chen Key Laboratory of Polar Materials and Devices (MOE) and department of Optoelectronics East China Normal University department of Physics China Three Gorges University Collaborative Innovation Center of Extreme Optics Shanxi University

NaSbS2was recently proposed as a novel photovoltaic semiconductor with earth-abundant component elements,but its fundamental material properties have not been well *** systematical first-principles calculations for its electronic,optical and defect properties were carried out in the present study,and the results show that:i)NaSbS2in the rocksalt-derived structure has a quasi-direct band gap and thus may have long minority carrier lifetime;ii) its absorption coefficients are as high as 1.～4～1.～5 cm-1.or the visible light and almost isotropic despite that the structure is distorted relative to the high-symmetry rocksalt structure;iii) the effective masses of the electron and hole carriers are anisotropic with much larger values along the z direction than in the x-y plane,and hence the orientational control of thin films should be important for enhancing the photovoltaic performance;iv) the valence and conduction band edges of NaSbS2are close to those of CuGaSe2) so the n-CdS/pCuGaSe2device structure can be inherited to form the n-CdS/p-NaSbS2solar cells;v) the acceptor defects (NaSbantisites and Na vacancies) have very high concentration,making the synthesized NaSbS2always be p-type;vi)the S-rich condition can suppress the formation of deep-level donor defects (S vacancies and SbNaantisites) and therefore should be adopted for fabricating high-efficiency NaSbS2solar cells.

关键词： NaSbS2 Photovoltaic semiconductor Optical absorption coefficients Defects First-principles calculation

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某三甲综合医院3.1.份住院病案首页主要诊断编码质量分析

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中国卫生标准管理 2024年第18期15卷 5-8页

作者：许慧娜吴玉连黄月凤侯毅翰陈丽君厦门大学附属第一医院病案办公室福建厦门361000 厦门市病案管理质量控制中心福建厦门361000

目的分析厦门市某三甲综合医院2023.1.1.月住院病案首页主要诊断编码质量,分析编码错误原因,提出有效的改进建议,以期提高医院住院病案首页主要诊断编码质量。方法采用分层抽样选取厦门市某三甲综合医院2023.1.1.月住院病案3.1.份,... 详细信息

目的分析厦门市某三甲综合医院2023.1.1.月住院病案首页主要诊断编码质量,分析编码错误原因,提出有效的改进建议,以期提高医院住院病案首页主要诊断编码质量。方法采用分层抽样选取厦门市某三甲综合医院2023.1.1.月住院病案3.1.份,由科室9名编码员对抽取的病案首页进行交叉互查,登记编码错误类型,分析编码错误原因。结果主要诊断编码错误3.3.,主诊编码错误率为1..65%。对错误类型归类:未认真分析病历资料占比48.44%,未掌握主要诊断编码原则占比27.48%,临床知识不足占比1..1.%,系统获取错误占比9.92%。结论注重病案编码专业人才队伍的建设,培养编码员的工作能力,推进病案管理系统改进和优化,有利于持续优化病案首页主要诊断编码质量。

关键词：病案首页主要诊断编码质量分析编码错误类型病案管理改进专业人才培养

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N-doped porous carbon nanofibers sheathed pumpkin-like Si/C composites as free-standing anodes for lithium-ion batteries

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Journal of Energy Chemistry 2021年第3期30卷 727-735页

作者： Yanfei Zeng Yudai huang Niantao Liu Xingchao {1. Yue Zhang Yong Guo Hong-Hui wu Huixin chen Xincun Tang Qiaobao Zhang Key Laboratory of Energy Materials Chemistry Ministry of EducationKey Laboratory of Advanced Functional MaterialsAutonomous RegionInstitute of Applied ChemistryCollege of ChemistryXinjiang UniversityUrumqi 830046XinjiangChina department of Materials Science and Engineering College of MaterialsXiamen UniversityXiamen 361005FujianChina Beijing Advanced Innovation Center for Materials Genome Engineering School of Materials Science and EngineeringUniversity of Science and Technology BeijingBeijing 100083China School of Chemistry and Chemical Engineering Central South UniversityChangsha 410083HunanChina Xiamen Institute of Rare earth Materials Haixi InstitutesChinese Academy of SciencesXiamen 361024FujianChina

Dramatic capacity fading and poor rate performance are two main obstacles that severely hamper the widespread application of the Si anode owing to its large volume variation during cycling and low intrinsic electrical *** mitigate these issues,free-standing N-doped porous carbon nanofibers sheathed pumpkin-like Si/C composites(Si/C-ZIF-8/CNFs)are designed and synthesized by electrospinning and carbonization methods,which present greatly enhanced electrochemical properties for lithium-ion battery *** particular structure alleviates the volume variation,promotes the formation of stable solid electrolyte interphase(SEI)film,and improves the electrical *** a result,the as-obtained free-standing Si/C-ZIF-8/CNFs electrode delivers a high reversible capacity of 945.5 mAh g^(-1. at 0.2 A g^(-1. with a capacity retention of 64% for 1.0 cycles,and exhibits a reversible capacity of 53..6 mA h g^(-1. at 0.5 A g^(-1. over 500 ***,the full cell composed of a freestanding Si/C-ZIF-8/CNFs anode and commercial LiNi_(1.3.Co_(1.3.Mn_(1.3.O_(2)(NCM)cathode shows a capacity of 63.4 mA h g^(-1. after 1.0 cycles at 0.2 C,which corresponds to a capacity retention of 60%.This rational design could provide a new path for the development of high-performance Si-based anodes.

关键词： Pumpkin-like silicon/carbon composites N-doped porous carbon nanofibers Free-standing anode Lithium-ion batteries

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Gut microbiota-derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model

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Animal Nutrition 2022年第3期10卷 111-123页

作者： Ke Zhang Yangbin xu Yuxin Yang Mengmeng Guo Ting Zhang Bo Zong Shuhong {1. Langda Suo Baohua Ma Xiaolong wang Yujiang wu Daniel Brugger Yulin chen Key Laboratory of Animal Genetics Breeding and Reproduction of Shaanxi ProvinceCollege of Animal Science and TechnologyNorthwest A&F UniversityYangling712100China College of Veterinary Medicine Northwest A&F UniversityYangling712100China Institute of Animal sciences Tibet Academy of Agricultural and Animal Husbandry SciencesLhasa850009China Institute of Animal Nutrition and Dietetics Vetsuisse-FacultyUniversity of Zurich8057ZurichSwitzerland

Early weaning induces intestinal injury,leading to a series of long-term symptoms such as inflammation,malabsorption and *** this study,we hypothesized that microbes and theirmetabolitesmodulate the host's inflammatory response to early weaning stress in a goatmodel.A total of 1. female Tibetan goat kids(n?9)wereweaned fromtheirmothers at 28 d(D28)and 60 d(D60)postpartum.D60 and D28 groupswere fed the same solid diet ad libitum fromweaning to 75 d of *** colonic epithelium was subject to RNAsequencing,the caecal digesta metabolomics were assessed by liquid chromatographyetandem mass spectrometry(LC-MS/MS),and the caecal microbiota composition was analysed by 1.S ribosomal RNA gene *** foundthatearlyweaningsubstantially increased the colonic pro-apoptotic gene expressionof B-cell lymphoma associated X(Bax),caspase-9,and caspase-3.and decreased the expression of zonula occludens-1.ZO-1.and claudin-1.P1..In addition,a significant Bacteroides acidifaciens enrichmentwas observed in the hindgut of early-weaned goats(P1.,which negatively correlated with lysophosphatidylcholine ***,the chemokine signaling,IL-1. signaling,and peroxisome proliferatorsactivated receptor(PPAR)signaling pathways were upregulated in the colonic mucosa of the early-weaned *** applying caecal microbiota transplantation from goats to defaunated C57/6J mice,we confirmed that caecalmicrobiota of D28 goat kids increased the relative abundance of *** and significantly upregulated the genes of Bax,G proteinecoupled receptor(GPR)1.9A,GPR 43.fatty acid binding protein 6,nuclear receptor subfamily 1.group H member 3.angiotensin converting enzyme 2,and IL-6 expression(P1.and claudin-1.protein expression in the mice jejunum and colon(P1..These results proposed that the hindgut microbiota andmetabolites mediate the barrier functionweakening duringearlyweaning,and the relative abundance of *** negatively corr

关键词： Hindgut microbiome Ruminant Dysbiosis Inflammation Colon

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Lateral variation in seismic velocities and rheology beneath the Qinling-Dabie orogen

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Science china {1. sciences 2017年第3期60卷 576-588页

作者： DENG YangFan chen Lin {1. Tao wu Jing Fabio ROMANELLI Giuliano Francesco PANZA State Key Laboratory of isotope Geochemistry Guangzhou institute of Geochemistry Chinese Academy of Sciences Guangzhou 510640 China State Key Laboratory of Lithospheric Evolution Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China Chinese Academy of sciences Center for Excellence in Tibetan Plateau {1. sciences Beijing 100101 China department of Mathematics and Geo{1. University of Trieste Via Weiss 1-34127 Trieste Italy Institute of Geophysics China Earthquake Administration Beijing 100081 China ISSO-International Seismic Safety Organization Viale San Francesco 12 1-64031 Arsita Italy

The Qinling-Dabie orogen is an important tectonic belt that trends east-west and divides continental china into northern and southern *** to its strong deformation,complicated structure,multiphase structural superposition and the massive exposed high and ultrahigh metamorphic rocks,its tectonic formation and geodynamical evolution are hot research topics *** studies mainly focused on the regional geological or geochemical aspects,whereas the geophysical constraints are few and isolated,in particular on the orogenic ***,we integrate the available P- and S-wave seismic and seismicity data,and construct the rheological structures along the Qinling-Dabie *** results demonstrate that:(1.there are strong lateral variations in the crustal velocity between the western and eastern sections of the Qinling-Dabie orogen,indicating the different origin and tectonic evolution between these two parts;(2) the lateral variations are also manifested in the rheological *** rigid blocks,such as South china and Ordos basin(North china Craton),resist deformation and show low *** weak regions,such as the margin of Tibet and western Qinling-Dabie experience strong deformation and accumulated stress,thus show active seismicity;(3. in the lower crust of most of the HP/UHP terranes the values of P-wave velocity are higher than the global average ones;finally(4) low P- and S-wave velocities and low strength in the lower crust and lithospheric mantle beneath Dabie indicate lithospheric delamination,and/or high temperature,and partial melting condition.

关键词： Qinling-Dabie orogen Deep seismic sounding Tomography Rheology Seismicity

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International experience of carbon neutrality and prospects of key technologies:Lessons for china

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Petroleum Science 2023年第2期20卷 893-909页

作者： Zheng-Meng Hou Ying Xiong Jia-Shun Luo Yan-Li Fang Muhammad Haris Qian-Jun chen Ye Yue Lin {1. Qi-chen wang Liang-Chao {3. Yi-Lin Guo Ya-chen Xie Institute of Subsurface Energy Systems Clausthal University of TechnologyClausthal-Zellerfeld38678Germany School of earth and Space {1. Peking UniversityBeijing100871China State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu610500SichuanChina Sino-German Energy Research Center Sichuan UniversityChengdu610065SichuanChina department of Petroleum&Gas Engineering University of Engineering&Technology54890LahorePakistan Yunnan Key Lab.of Sino-German Blue Mining and Utilization of Special Underground Space Kunming650093YunnanChina Sino-German Research Institute of Carbon Neutralization and Green Development Zhengzhou UniversityZhengzhou450000HenanChina State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan430071HubeiChina

Carbon neutrality(or climate neutrality)has been a global consensus,and international experience exchange is *** the differences in the degree of social development,resource endowment and technological level,each country should build a carbon-neutral plan based on its national *** with other major developed countries(e.g.,Germany,the United States and Japan),china's carbon neutrality has much bigger challenges,including a heavy and time-pressured carbon reduction task and the current energy structure that is over-dependent on fossil *** we provide a comprehensive review of the status and prospects of the key technologies for low-carbon,near-zero carbon,and negative carbon *** innovations associated with coal,oil-gas and hydrogen industries and their future potential in reducing carbon emissions are particularly explained and *** on integrated analysis of international experience from the world's major developed countries,in-depth knowledge of the current and future technologies,and china's energy and ecological resources potential,five lessons for the implementation of china's carbon neutrality are proposed:(1.transformation of energy production pattern from a coal-dominated pattern to a diversified renewable energy pattern;(2)renewable power-to-X and large-scale underground energy storage;(3.integration of green hydrogen production,storage,transport and utilization;(4)construction of clean energy systems based on smart sector coupling(ENSYSCO);(5)improvement of ecosystem carbon sinks both in nationwide forest land and potential desert in Northwest *** paper provides an international perspective for a better understanding of the challenges and opportunities of carbon neutrality in china,and can serve as a theoretical foundation for medium-long term carbon neutral policy formulation.

关键词： International experience Carbon reduction technologies Carbon neutrality Energy transition Underground energy storage Carbon capture,utilization and storage(CCUS)

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