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Si-C Foam Porous-Medium Combustion Power-Generation System for Low-Calorific-Value Biomass Syngas

Journal of Thermal Science 2025年第1期34卷 206-222页

作者： YANG Jianwen chen wei CAO Bingwei LIU Xinhui LI Hang College of Mechanical and Aerospace Engineering Jilin University School of Mechanical and Vehicle Engineering Changchun University

Syngas produced from the gasification of organic feedstocks from biomass is one of the clean and sustainable sources of *** advantages of simple access and renewability of biomass energy can meet the energy needs of temporary power *** study presents a biomass power-generation system for vehicular *** biomass and a free-piston Stirling engine generator（FPSEG） as the primary material and prime mover,respectively,biomass energy is converted into electricity by combusting the syngas to heat the *** and key parameter design for biomass gasification and thermoelectric conversion systems within a power generation system were performed.A porous medium area was constructed using Si-C foam ceramics to obtain an energy-conversion experimental *** effects of bed height,porosity,porous-region diameter,and air-intake conditions on the power-generation performance were investigated,and optimisations were performed for the thermoelectric conversion *** rate of increase during FPSEG power generation first increased and then decreased with increasing bed height,peaking at a bed height of 40 *** increasing porous-region diameter accelerated FPSEG power generation,whereas porosity changes in the porous media did not significantly affect the rate of change during FPSEG power *** increasing air intake,the rate of increase during power generation first increased and then *** maximum change rate and the highest thermoelectric conversion efficiency of the power-generation system occurred at 9.5 m3/h and 6.5 m3/h（～45.1%）air intakes,*** the thermal inertia and combustion structure of the thermoelectric conversion system significantly increased the power-generation rate of the system,with 1.8 W/s being observed at a 9.7 m3/h air intake.

关键词： biomass combined heat and power (CHP) gasification porous media combustion power generation

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Precise gradient separation of nanoparticles using reduced graphene oxide-polyoxomolybdate membranes

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Science China Chemistry 2025年第1期68卷 209-216页

作者： Yixin Yang Wanlei Zhao Ruoxuan Zheng Hongqiang Li wei chen Yu-Fei Song State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology Quzhou Institute for Innovation in Resource Chemical Engineering

The purification and size sieving of nanoparticles （NPs） represents a significant scientific ***,the r GO-polyoxometalates (POMs=PMo12,Mo132and Mo368) membranes were fabricated successfully via a simple and scalable POMsassisted in-situ photoreduction *** the mass ratio of r GO to PMo12was 1:30,the resultant r GO-PMo12membranes with highly ordered and uniform nanochannels of 1.0 nm can be obtained,which showed an accurate carbon quantum dots（CQDs） separation with a cut-off size approximately 1.0 *** increase of the size of the interlayered POMs from PMo12（1.0 nm）,{Mo132}（2.9 nm） to{Mo368}（3.8 nm）,the resultant r GO-PMo12,r GO-Mo132and r GO-Mo368exhibited precise gradient separation of CQDs and Au nanoparticles by size exclusion *** results pave a promising way to construct new twodimensional （2D） membranes for highly efficient size-selective separation.

关键词： reduced graphene oxide polyoxometalates membranes gradient separation nanoparticles

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Tranylcypromine upregulates Sestrin 2 expression to ameliorate NLRP3-related noise-induced hearing loss

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Neural Regeneration Research 2025年第5期20卷 1483-1494页

作者： Xihang chen Zhifeng chen Menghua Li weiwei Guo Shuolong Yuan Liangwei Xu Chang Lin Xi Shi wei chen Shiming Yang Senior Department of Otolaryngology Head and Neck Surgery Chinese PLA General HospitalChinese PLA Medical SchoolBeijingChina State Key Laboratory of Hearing and Balance Science BeijingChina National Clinical Research Center for Otolaryngologic Diseases BeijingChina Key Laboratory of Hearing Science Ministry of EducationBeijingChina Beijing Key Laboratory of Hearing Impairment Prevention and Treatment BeijingChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Otolaryngology Head and Neck Surgery The 940th Hospital of Joint Logistics Support Force of Chinese PLALanzhouGansu ProvinceChina Key Laboratory of Tropical Biological Resources of Ministry of Education School of Pharmaceutical SciencesHainan UniversityHaikouHainan ProvinceChina Academician Workstation of Hainan University School of Pharmaceutical SciencesYazhou BaySanyaHainan ProvinceChina

Noise-induced hearing loss is the primary non-genetic factor contributing to auditory ***,there are currently no effective pharmacological interventions for patients with noise-induced hearing ***,we present evidence suggesting that the lysine-specific demethylase 1 inhibitor–tranylcypromine is an otoprotective agent that could be used to treat noise-induced hearing loss,and elucidate its underlying regulatory *** established a mouse model of permanent threshold shift hearing loss by exposing the mice to white broadband noise at a sound pressure level of 120 d B for 4 *** found that tranylcypromine treatment led to the upregulation of Sestrin2(SESN2)and activation of the autophagy markers light chain 3B and lysosome-associated membrane glycoprotein 1 in the cochleae of mice treated with *** noise exposure group treated with tranylcypromine showed significantly lower average auditory brainstem response hearing thresholds at click,4,8,and 16 k Hz frequencies compared with the noise exposure group treated with *** findings indicate that tranylcypromine treatment resulted in increased SESN2,light chain 3B,and lysosome-associated membrane glycoprotein 1 expression after noise exposure,leading to a reduction in levels of 4-hydroxynonenal and cleaved caspase-3,thereby reducing noise-induced hair cell ***,immunoblot analysis demonstrated that treatment with tranylcypromine upregulated SESN2 expression via the autophagy *** treatment also reduced the production of NOD-like receptor family pyrin domaincontaining 3(NLRP3)*** conclusion,our results showed that tranylcypromine treatment ameliorated cochlear inflammation by promoting the expression of SESN2,which induced autophagy,thereby restricting NLRP3-related inflammasome signaling,alleviating cochlear hair cell loss,and protecting hearing *** findings suggest that inhibiting lysine-specific demethylase 1 is a

关键词： 4-hydroxynonenal apoptosis autophagy cleaved caspase-3 inflammation NOD-like receptor family pyrin domain-containing 3(NLRP3) noise-induced hearing loss oxidative stress Sestrin2 tranylcypromine

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PI3K/AKT signaling and neuroprotection in ischemic stroke:molecular mechanisms and therapeutic perspectives

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Neural Regeneration Research 2025年第10期20卷 2758-2775页

作者： Tianlong Liu Xiaolin Li Xiaowei Zhou wei chen Aidong Wen Minna Liu Yi Ding Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina Department of Pharmacy The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina Department of Pharmacy The 944 Hospital of Joint Logistics Support Forces of Chinese PLAJiuquanGansu ProvinceChina Department of Nephrology The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina

It has been reported that the PI3K/AKT signaling pathway plays a key role in the pathogenesis of ischemic *** a result,the development of drugs targeting the PI3K/AKT signaling pathway has attracted increasing attention from *** article reviews the pathological mechanisms and advancements in research related to the signaling pathways in ischemic stroke,with a focus on the PI3K/AKT signaling *** key findings include the following:(1)The complex pathological mechanisms of ischemic stroke can be categorized into five major types:excitatory amino acid toxicity,Ca^(2+)overload,inflammatory response,oxidative stress,and apoptosis.(2)The PI3K/AKT-mediated signaling pathway is closely associated with the occurrence and progression of ischemic stroke,which primarily involves the NF-κB,NRF2,BCL-2,mTOR,and endothelial NOS signaling pathways.(3)Natural products,including flavonoids,quinones,alkaloids,phenylpropanoids,phenols,terpenoids,and iridoids,show great potential as candidate substances for the development of innovative anti-stroke medications.(4)Recently,novel therapeutic techniques,such as electroacupuncture and mesenchymal stem cell therapy,have demonstrated the potential to improve stroke outcomes by activating the PI3K/AKT signaling pathway,providing new possibilities for the treatment and rehabilitation of patients with ischemic *** investigations should focus on the direct regulatory mechanisms of drugs targeting the PI3K/AKT signaling pathway and their clinical translation to develop innovative treatment strategies for ischemic stroke.

关键词： apoptosis autophagy inflammation ischemic stroke neuroprotection oxidative stress pathogenesis phosphatidylinositol 3-kinase protein kinase B therapeutics

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A six-variable quasi-3D isogeometric approach for free vibration of functionally graded graphene origami-enabled auxetic metamaterial plates submerged in a fluid medium

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 157-176页

作者： wei chen Zhihong TANG Yufen LIAO Linxin PENG College of Civil Engineering University of South China College of Civil Engineering and Architecture Guangxi University Key Laboratory of Disaster Prevention and Structural Safety of Ministry of Education Guangxi University

This paper presents, for the first time, an effective numerical approach based on the isogeometric analysis(IGA) and the six-variable quasi-three dimensional(3D)higher-order shear deformation theory(HSDT) to study the free vibration characteristics of functionally-graded(FG) graphene origami(GOri)-enabled auxetic metamaterial(GOEAM) plates submerged in a fluid medium. The plate theory incorporates the thickness stretching and the effects of transverse shear deformation without using any shear correction factors. The velocity potential function and Bernoulli's equation are used to derive the hydrodynamic pressure acting on the plate surface. Both horizontally and vertically immersed plate configurations are considered here in the form of inertia *** plates are composed of multilayer GOEAMs, with the GOri content varying through the plate's thickness in a layer-wise manner. This design results in graded auxetic *** material properties are evaluated by mixing rules and a genetic programming(GP)-assisted micromechanical model. The governing equations of motion for the FG-GOEAM plates immersed in a fluid medium are derived by Hamilton's principle. After validating the convergence and accuracy of the present model, a comprehensive parametric study is carried out to examine the effects of the GOri content, GOri distribution pattern, GOri folding degree, fluid level, immersed depth, and geometric parameter on the natural frequencies of the FG-GOEAM plates. The results show that the natural frequencies for the four GOri distribution patterns increase with the increase in the layer number when the lay number is fewer than 10, and then stabilize after the layer number reaches ***, in general, the natural frequency of the FG-GOEAM plate in a vacuum or fluid increases when the GOri content increases, while decreases when the GOri folding degree increases. Some additional findings related to the numerical results are presented in the conclusions. It is belie

关键词： Equations of motion

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人不是物:社会认知的稽古维新

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心理学报 2025年第1期57卷 173-189页

作者：董达陈巍绍兴文理学院心理学系大脑、心智与教育研究中心浙江绍兴312000 中国人民大学哲学与认知科学交叉平台北京100080

当代社会认知的理论版图可分为经典概念工具箱与正在与之对抗的新概念工具两部分。经考证,理论论和模拟论等经典概念工具集中诞生于1980年代的美国认知科学界,可以被视为1956认知革命蔓延至社会心理学领域的产物,而新概念工具可以被视... 详细信息

当代社会认知的理论版图可分为经典概念工具箱与正在与之对抗的新概念工具两部分。经考证,理论论和模拟论等经典概念工具集中诞生于1980年代的美国认知科学界,可以被视为1956认知革命蔓延至社会心理学领域的产物,而新概念工具可以被视为与第二代认知革命相适合的替代理论。历史上,社会心理学接受了认知主义的“物”的抽象认知原理,也全盘接受了它带来的理论负荷,即对“人”的感知被还原为对“物”的感知,并且隶属于后者。然而,基于“物”的抽象认知原理始终无法与社会认知的以“人”为本的实践经验相结合,也未能实现该领域的自治。事实上,这一理论困难并非一直存在于“社会认知”的历史路径中,至少在以Heider为标志性人物的1950年代早期社会认知中便不是这样。Heider“人不是物”理论体系在个体层面上包括知觉实在论、事件归因和生命性−非生命性范畴区分三个部分,但是第三个理论部件彼时囿于作者主题侧重、证据不足、技术匮乏等多种原因未能完成。结合当代来自演化和比较的、行为和发展的以及神经通路假设的新证据,通过重新发掘并最终完整构建了“人不是物”论题,尝试为当代社会认知理论困难提供一个建设性意见。

关键词：社会认知人的感知认知革命生命性主体间性

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系统论视阈下特别重大突发事件应急治理失灵模型研究

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灾害学 2025年第1期40卷 140-145页

作者：陈梁陈威王修来南京信息工程大学管理工程学院江苏南京210044 南京信息工程大学人才大数据研究院江苏南京210044 东部战区总医院医学信息数据室江苏南京210002

顺应韧性治理的发展潮流,基于系统论破解特别重大突发事件应急治理失灵困境。结合中国应急管理部官方网站公布的特别重大突发事件调查报告,从“失灵溯源”的视角综合审视突发事件应急治理过程,根据技术应用、情报协同、组织治理在应急... 详细信息

顺应韧性治理的发展潮流,基于系统论破解特别重大突发事件应急治理失灵困境。结合中国应急管理部官方网站公布的特别重大突发事件调查报告,从“失灵溯源”的视角综合审视突发事件应急治理过程,根据技术应用、情报协同、组织治理在应急治理过程中赋能与失灵的双重效应,构建特别重大突发事件应急治理失灵模型。研究发现,技术应用子系统、情报协同子系统和组织治理子系统分别通过技术支持、数据获取和信息整合;情报收集、分析协同和共享传递;指挥协调、资源调度和决策执行的作用路径,共同影响特别重大突发事件的应急治理效能。在实际治理过程中,需要解决系统和要素之间的失灵困境,才能更好地赋能特别重大突发事件应急治理韧性。

关键词：特别重大突发事件应急治理失灵模型系统论

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凡纳滨对虾肌质钙结合蛋白纯化鉴定、理化特性及抗原表位分析

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食品科学 2025年第2期46卷 30-37页

作者：陈伟周军君陈雅纯贾英民马爱进北京工商大学食品与健康学院北京100048

以凡纳滨对虾(Penaeus vannamei)为原料,分离纯化和鉴定过敏原肌质钙结合蛋白(sarcoplasmiccalcium-binding protein,SCP),对其理化性质(免疫活性、热稳定性、pH值稳定性及消化稳定性)、二级结构和抗原表位进行研究。结果表明:采用蛋白... 详细信息

以凡纳滨对虾(Penaeus vannamei)为原料,分离纯化和鉴定过敏原肌质钙结合蛋白(sarcoplasmiccalcium-binding protein,SCP),对其理化性质(免疫活性、热稳定性、pH值稳定性及消化稳定性)、二级结构和抗原表位进行研究。结果表明:采用蛋白粗提、硫酸铵分级沉淀、阴离子交换层析等步骤纯化得到的蛋白分子质量为21.6 kDa,经鉴定,该蛋白为凡纳滨对虾SCP,肽段覆盖率达93.26%。凡纳滨对虾SCP具有较强的免疫活性,在热处理温度≥65℃和强酸强碱条件下免疫活性减弱;SCP对肠液消化具有较强的稳定性,而对胃液消化稳定性较差。凡纳滨对虾SCP的二级结构中α-螺旋、β-折叠、β-转角和无规卷曲的相对含量分别为26%、16.9%、17.5%、39.6%。利用生物信息学工具结合免疫学技术最终预测识别出8条凡纳滨对虾SCP抗原表位。

关键词：凡纳滨对虾肌质钙结合蛋白稳定性抗原表位

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新型二维声子晶体带隙特性及调控方法研究

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大连理工大学学报 2025年第1期65卷 48-55页

作者：胡启国胡皓魏晨胡豁然重庆交通大学机电与车辆工程学院重庆400074 国网重庆市电力公司信息通信分公司重庆401120

为拓宽声子晶体弹性波带隙,提出一种关于基体双侧对称的声子晶体结构模型.采用有限元法计算了该声子晶体的能带结构和本征模态,基于局域共振机理深入分析了其带隙的形成机理,通过改变几何参数及施加等轴预拉伸应变的方法对该声子晶体的... 详细信息

为拓宽声子晶体弹性波带隙,提出一种关于基体双侧对称的声子晶体结构模型.采用有限元法计算了该声子晶体的能带结构和本征模态,基于局域共振机理深入分析了其带隙的形成机理,通过改变几何参数及施加等轴预拉伸应变的方法对该声子晶体的带隙进行被动调控与主动调控.仿真结果表明:所提声子晶体结构基体中的长波行波与振子的谐振相互耦合作用产生一条局域共振带隙,通过优化几何参数可以获得起始频率更低的宽频带隙,对结构施加等轴预拉伸应变可以有效拓宽带隙且带隙宽度随着预拉伸应变的增大而变宽.研究结果为声子晶体的带隙主动调控提供了方案,为结构减振降噪提供了新思路.

关键词：声子晶体带隙特性带隙调控预拉伸应变

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河口海岸的“颜值”评价:环境亲民指标研究

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生态经济 2025年第1期41卷 52-59页

作者：张懿璇张宇轩陈唯中国环境科学研究院北京100012

当前是美丽中国建设的关键时期。美丽中国要坚持以人民为中心,如何突出人民至上、让工作成效体现在人民群众直观感受上,将人民群众直观感受纳入相关考核与评价指标,是美丽中国建设的新任务和新挑战。论文从设计制定水环境的“亲民指标... 详细信息

当前是美丽中国建设的关键时期。美丽中国要坚持以人民为中心,如何突出人民至上、让工作成效体现在人民群众直观感受上,将人民群众直观感受纳入相关考核与评价指标,是美丽中国建设的新任务和新挑战。论文从设计制定水环境的“亲民指标”入手,以亲水空间具备的感性工学特征为基础,采用感性工学方法设计亲民指标,能够直观地体现水环境的用户满意度,有助于确定水环境治理和亲水空间的社会资源价值,进一步丰富和改善水环境的社会功能。同时,感性工学方法也能够应用在环保设施公众开放等公众参与并获取情感体验的设施和项目中,有助于全面把握公众体验、提高公众满意度,形成公众与生态环境部门积极互动的良性循环,共同促进生态环境治理体系建设。

关键词：感性工学亲水空间 Kano模型亲民指标河口海岸美丽中国建设

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