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Journal of Integrative Agriculture 2022年第8期21卷 2305-2318页

作者： chao kai-xiang WU Cai-juan LI Juan WANG Wen-li WANG Bao-tong LI Qiang State Key Laboratory of Crop Stress Biology for Arid Areas College of Plant ProtectionNorthwest A&F UniversityYangling 712100P.R.China College of Chemistry Biology and Environment Yuxi Normal UniversityYuxi 653100P.R.China

Stripe rust,caused by Puccinia striiformis ***(Pst),is one of the most destructive diseases on wheat ***,a wheat landrace released from Gansu Province in China since 1950,exhibits adult-plant resistance to stripe rust for several *** elucidate the genetic basis of stripe rust resistance,Wudubaijian was crossed with the high susceptible cultivar Mingxian 169,and stripe rust tests of both parents and the F2:3 lines were conducted in four environments of Yangling and Tianshui in 2015 and 2016,*** relative area under disease progress curve(rAUDPC)of Mingxian 169/Wudubaijian F_(2:3) lines showed that the resistance of Wudubaijian was controlled by quantitative trait loci(QTL).Combined with phenotypic data and molecular markers,two stable QTLs were identified in ***-5A with the phenotypic variance of 15.02-40.26% was located between 5AS1-0.40-0.75 and 5AS3-0.75-0.98 of chromosome 5AS,and ***-2B.1 with the phenotypic variance of 9.54-10.40%was located in the bin C-2BS1-0.53 of chromosome *** the location of flanking markers and epistasis analysis,***-5A may be a new major QTL that can be used in conjunction with other stripe rust resistance genes(QTLs).

关键词： Triticum aestivum Puccinia striiformis f.sp.tritici adult-plant resistance QTL mapping

Molecular Mapping of a Stripe Rust Resistance Gene YrH9020a Transferred from Psathyrostachys huashanica Keng on Wheat Chromosome 6D

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Journal of Integrative Agriculture 2014年第12期13卷 2577-2583页

作者： LIU Ze-guang YAO Wei-yuan SHEN Xue-xue chao kai-xiang FAN Yu LI Min-zhou WANG Bao-tong LI Qiang JING Jin-xue State Key Laboratory of Crop Stress Biology for Arid Areas College of Plant Protection Northwest A&F University

Stripe rust （yellow rust）, caused by Puccinia striiformis f. sp. tritici （Pst）, is one of the most devastating diseases of wheat throughout the world. H9020-1-6-8-3 is a translocation line originally developed from interspeciifc hybridization between wheat line 7182 and Psathyrostachys huashanica Keng and is resistant to most Pst races in China. To identify the resistance gene（s） in the translocation line, H9020-1-6-8-3 was crossed with susceptible cultivar Mingxian 169, and seedlings of the parents, F1, F2, F3, and BC1 generations were tested with prevalent Chinese Pst race CYR32 under controlled greenhouse conditions. The results indicated that there is a single dominant gene, temporarily designated as YrH9020a, conferring resistance to CYR32. The resistance gene was mapped by the F2 population from Mingxian 169/H9020-1-6-8-3. It was linked to six microsatellite markers, including Xbarc196, Xbarc202, Xbarc96, Xgpw4372, Xbarc21, and Xgdm141, lfanked by Xbarc96 and Xbarc202 with at 4.5 and 8.3 cM, respectively. Based on the chromosomal locations of these markers and the test of Chinese Spring （CS） nullitetrasomic and ditelosomic lines, the gene was assigned to chromosome 6D. According to the origin and the chromosomal location, YrH9020a might be a new resistance gene to stripe rust. The lfanking markers linked to YrH9020a could be useful for marker-assisted selection in breeding programs.

关键词： Puccinia striiformis f. sp. tritici Psathyrostachys huashanica Keng resistance gene genetic analysis SSR markers

Repetitive traumatic brain injury–induced complement C1–related inflammation impairs long-term hippocampal neurogenesis

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Neural Regeneration Research 2025年第3期20卷 821-835页

作者： Jing Wang Bing Zhang Lanfang Li Xiaomei Tang Jinyu Zeng Yige Song chao Xu kai Zhao Guoqiang Liu Youming Lu Xinyan Li kai Shu Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Neurosurgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Pathophysiology School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Institute for Brain Research Wuhan Center of Brain ScienceHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Graduate Student Chongqing Medical UniversityChongqingChina Department of Basic Medicine School of Medical ScienceHubei University for NationalitiesEnshiHubei ProvinceChina Department of Anatomy School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Repetitive traumatic brain injury impacts adult neurogenesis in the hippocampal dentate gyrus,leading to long-term cognitive ***,the mechanism underlying this neurogenesis impairment remains *** this study,we established a male mouse model of repetitive traumatic brain injury and performed long-term evaluation of neurogenesis of the hippocampal dentate gyrus after repetitive traumatic brain *** results showed that repetitive traumatic brain injury inhibited neural stem cell proliferation and development,delayed neuronal maturation,and reduced the complexity of neuronal dendrites and *** with repetitive traumatic brain injuryalso showed deficits in spatial memory ***,following repetitive traumatic brain injury,neuroinflammation was enhanced in the neurogenesis microenvironment where C1q levels were increased,C1q binding protein levels were decreased,and canonical Wnt/β-catenin signaling was *** inhibitor of C1 reversed the long-term impairment of neurogenesis induced by repetitive traumatic brain injury and improved neurological *** findings suggest that repetitive traumatic brain injury–induced C1-related inflammation impairs long-term neurogenesis in the dentate gyrus and contributes to spatial memory retrieval dysfunction.

关键词： complement C1 dendrite dentate gyrus hippocampus neural stem cell neurogenesis neuroinflammation neurological function neuron traumatic brain injury

Genetic analysis and molecular mapping of a stripe rust resistance gene in wheat-Leymus mollis translocation line M8926-2

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Genetic analysis and molecular mapping of a stripe rust resi...

Global research status and trends of somatic symptom disorder: A bibliometric study

中国植物病理学会2015年学术年会

作者：李强 chao kai-xiang LI Qian ZHANG Yu JING Jin-xue 王保通康振生 State Key Laboratory of Crop Stress Biology for Arid Areas/College of Plant Protection Northwest A&F University

Stripe rust,caused by Puccinia striiformis ***(Pst),is one of the most widespread and destructive wheat diseases *** resistant cultivars is the preferred control of the disease,but only a few effective genes are available.M8926-2,a translocation line developed from interspecific hybridization between Leymus mollis and common wheat genotype 7182,is highly resistant to the prevalent Chinese Pst *** identify gene(s) for stripe rust resistance,M8926-2was crossed with susceptible genotype Mingxian 169,and seedlings of parents and F,F and Fprogenies were tested with the most prevalent Pst race CYR32 under controlled greenhouse conditions.M8926-2 has a single dominant gene,designated as YrM8926,conferring all-stage resistance to *** sequence repeat(SSR) technique was used to identify molecular markers linked to YrM8926.A linkage group of seven SSR markers was constructed for YrM8926 using 191 F population plants and the gene was located on wheat chromosome *** pedigree and disease assessments suggested that YrM8926 likely originally derived from *** stripe rust resistance gene and closely linked molecular markers should be useful for pyramiding with other genes to develop wheat cultivars with highlevel and durable resistance to stripe rust.

关键词： Puccinia striiformis f.sp.tritici wheat-L.mollis translocation line resistance gene genetic analysis molecular mapping

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World Journal of Psychiatry 2025年第1期15卷 168-178页

作者： chao Yang Kun Zhang Qian Wang Shuai Wang Huan Li kai Zhang Department of Psychiatry Beijing Luhe HospitalCapital Medical UniversityBeijing 100001China Department of Psychiatry Chaohu Hospital of Anhui Medical UniversityHefei 238000Anhui ProvinceChina School of Medicine Jiangxi University of TechnologyNanchang 510001Jiangxi ProvinceChina School of Public Health Zhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina

BACKGROUND With the growing scholarly and clinical fascination with somatic symptom dis-order(SSD),a bibliometric analysis is *** To conduct a bibliometric analysis to investigate the current status and frontiers of *** The documents related to SSD are obtained from the web of science core collection database(WoSCC),and VOSviewer 1.6.16 from January 1,2000 to December 31,2023,and the WoSCC’s literature analysis wire were used to conduct the biblio-metric *** A total of 567 documents related to SSD were included,and 2325 authors across 947 institutions from 57 countries/regions have contributed to SSD research,published in 277 *** most productive author,institution,country and journal were Löwe B,University of Hamburg,Germany,and Journal of Psycho-somatic Research *** first high-cited document was published in the Journal of Psychosomatic Research in 2013 by Dimsdale JE and colleagues,which explored the rationale behind the SSD diagnosis introduction in diagnostic and statistical manual of mental *** In conclusion,the main research hotspots and frontiers in the field of SSD are validity and reliability of the SSD criteria,functional impairment of SSD,and the treatment for *** high-quality studies are needed to assess the diagnosis and treatment of SSD.

关键词： Somatic symptom disorder Validity and reliability Functional impairment Treatment Bibliometric analysis

陕西省115个小麦品种(系)抗条锈病基因的分子检测

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植物病理学报 2015年第6期45卷 632-640页

作者：李敏州李强巢凯翔申雪雪樊玉王阳王保通旱区作物逆境生物学国家重点实验室/西北农林科技大学植物保护学院杨凌712100

为掌握陕西省主栽与后备小麦品种对我国条锈菌的抗性水平,明确其抗锈基因分布,本研究选用条锈菌流行小种CYR32和新毒性小种V26对115份陕西省主栽和后备小麦品种(系)进行苗期抗病性鉴定,并分别利用抗条锈病基因Yr5、Yr9(1B/1R)、Yr10、Y... 详细信息

为掌握陕西省主栽与后备小麦品种对我国条锈菌的抗性水平,明确其抗锈基因分布,本研究选用条锈菌流行小种CYR32和新毒性小种V26对115份陕西省主栽和后备小麦品种(系)进行苗期抗病性鉴定,并分别利用抗条锈病基因Yr5、Yr9(1B/1R)、Yr10、Yr18和Yr26的紧密连锁分子标记对这115份材料进行了分子检测。结果表明,供试小麦品种(系)中,抗CYR32的有61份,占53.04%;抗V26的有84份,占73.04%;对2个小种均抗病的有50份,占43.48%。分子检测发现115份材料均不含有Yr10;可能携带Yr9基因的有41份,占35.65%;可能含有Yr5、Yr18和Yr26的材料分别为3份、3份和2份,占2.61%、2.61%和1.74%。因此,当前陕西省主栽与后备小麦品种(系)对CYR32和V26的抗性整体水平还有待进一步提高,Yr9分布频率较高,而Yr5、Yr10、Yr18和Yr26分布频率较低,建议在以后小麦育种中减少Yr9的使用,加强利用Yr5和Yr18与其他有效基因聚合培育持久抗条锈病品种。

关键词：小麦小麦条锈病抗病基因分子检测陕西省

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龙桑和垂桑胚胎发育观察及其异常现象

种子 2010年第4期29卷 23-27页

作者：巢凯翔李汉章付祖军李婵张玲丽西北农林科技大学农学院陕西杨凌712100

以桑科植物的两个变种龙桑与垂桑的雌株为材料(种植园内无雄株),采用常规石蜡切片法,对单性结实桑科植物的胚胎发育过程进行观察。结果表明:单性结实的垂桑和龙桑胚胎发育过程基本相似。大孢子卵细胞不经过授粉受精直接开始发育,发育成... 详细信息

以桑科植物的两个变种龙桑与垂桑的雌株为材料(种植园内无雄株),采用常规石蜡切片法,对单性结实桑科植物的胚胎发育过程进行观察。结果表明:单性结实的垂桑和龙桑胚胎发育过程基本相似。大孢子卵细胞不经过授粉受精直接开始发育,发育成类似于合子的胚状体结构,再进行分裂,依次经棒状形、球形、心形、鱼雷形,至果实成熟时形成子叶胚。其胚珠倒生,胚囊发育类型属于蓼形胚囊,生殖方式属于二倍体孤雌生殖。在种子发育过程中发现,珠心、珠被细胞解体、大孢子卵细胞不正常分裂等异常现象。

关键词：桑树胚胎发育单性结实解剖

源于柔软滨麦草抗小麦条锈病基因YrElm的遗传分析与SSR标记

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植物病理学报 2014年第6期44卷 641-650页

作者：张玉巢凯翔高旭柳泽光姚未远李强王保通旱区作物逆境生物学国家重点实验室/西北农林科技大学植物保护学院杨凌712100

M852-1是由柔软滨麦草和普通小麦7182经杂交和回交培育的易位系。苗期抗病性鉴定结果表明,M852-1对CYR29、CYR31、CYR32、CYR33、Su11-4、Su11-7和V26等7个中国小麦条锈菌主要生理小种或新的致病类型均表现免疫至高抗,是一个较好的抗条... 详细信息

M852-1是由柔软滨麦草和普通小麦7182经杂交和回交培育的易位系。苗期抗病性鉴定结果表明,M852-1对CYR29、CYR31、CYR32、CYR33、Su11-4、Su11-7和V26等7个中国小麦条锈菌主要生理小种或新的致病类型均表现免疫至高抗,是一个较好的抗条锈资源材料。用条锈菌流行小种CYR33对M852-1与铭贤169杂交F1、F2、F3和BC1代进行抗性鉴定与遗传分析,发现M852-1对CYR33的抗条锈性由1对隐性基因控制,暂定名为Yr Elm。以F2代分离群体构建作图群体,利用集群分离分析法,筛选到与Yr Elm连锁的5个SSR标记:Xcfd35、Xgwm161、Xwmc630、Xgwm533和Xcfd34,并将Yr Elm定位于小麦染色体3DS上。Yr Elm两侧最近2个SSR标记Xcfd35与Xgwm161的遗传距离分别为6.5 c M和4.2 c M。抗锈性鉴定、系谱分析以及分子标记检测结果表明,该抗病基因来源于柔软滨麦草。综合基因来源、分子检测及染色体位点等方面的分析,认为Yr Elm可能是一个新的抗条锈病基因。用该基因两侧最近两个标记Xcfd35和Xgwm161检测68个甘肃和黄淮麦区小麦品种(系),10个(14.7%)品种能扩增出与M852-1相同的条带。进一步进行抗病性及系谱分析表明,这10个品种均不含Yr Elm。本研究结果为利用Yr Elm进行分子标记辅助育种和进一步的精细定位奠定了基础。

关键词：小麦条锈病柔软滨麦草抗病基因遗传分析 SSR标记

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面向工业互联网的语义编码传输方法及应用

中山大学学报（自然科学版）（中英文） 2025年第1期64卷 51-60页

作者：牛凯鲁延鹏董超北京邮电大学人工智能学院北京100876 泛网无线通信教育部重点实验室北京100876 鹏城实验室广东深圳518055

通过将语义通信技术引入工业网络,构建了一个面向工业互联网的语义编码传输系统。系统中设计了语义编解码器以提取信源中的语义信息,相对于传统通信系统,基于语义信息的通信有更高的信息压缩效率与更高的符号差错容忍能力。同时引入信... 详细信息

通过将语义通信技术引入工业网络,构建了一个面向工业互联网的语义编码传输系统。系统中设计了语义编解码器以提取信源中的语义信息,相对于传统通信系统,基于语义信息的通信有更高的信息压缩效率与更高的符号差错容忍能力。同时引入信源信道联合编解码器,以信源信道联合编码的方式将语义信息转化为信道符号传输,进一步提升系统对工业网络通信资源的利用效率。所有编解码器均构建在深度神经网络架构Transformer上,确保了编解码器对语义信息的理解能力及系统的泛化能力。在工业药品生产场景中,对该系统进行测试,结果显示:相较于传统通信方案,该语义编码传输系统在图像重建质量和传输处理速度方面均有显著提升。且系统对下游任务的性能影响极小,保证了工业生产中如缺陷检测等关键任务的准确性。

关键词：工业互联网数据压缩与传输语义通信深度学习

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普通小麦‘Holdfast’条锈病成株抗性QTL定位

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作物学报 2019年第12期45卷 1832-1840页

作者：杨芳萍刘金栋郭莹贾奥琳闻伟鄂巢凯翔伍玲岳维云董亚超夏先春甘肃省农业科学院小麦研究所甘肃兰州730070 中国农业科学院作物科学研究所/国家小麦改良中心北京100081 中国农业科学院深圳农业基因组研究所广东深圳518120 西北农林大学植保学院陕西杨凌712100 四川省农业科学院作物研究所四川成都610066 天水农业科学研究所甘肃天水741200

Holdfast是来自英国的小麦品种,多年来一直保持良好的条锈病持久抗性。本研究目的是发掘Holdfast的条锈病成株抗性基因及其紧密连锁的分子标记,为小麦持久抗性品种选育提供材料和方法。利用铭贤169和Holdfast杂交后代重组自交系(recombi... 详细信息

Holdfast是来自英国的小麦品种,多年来一直保持良好的条锈病持久抗性。本研究目的是发掘Holdfast的条锈病成株抗性基因及其紧密连锁的分子标记,为小麦持久抗性品种选育提供材料和方法。利用铭贤169和Holdfast杂交后代重组自交系(recombinant inbred lines,RIL)群体,于2014—2015和2015—2016年度在甘肃甘谷、甘肃中梁和四川成都进行条锈病成株抗性鉴定,并统计最大严重度(maximum disease severity,MDS)。基于小麦660K SNP芯片和BSA(bulked segregant analysis)技术初步确定抗病基因所在的染色体后,将目标区域的SNP标记转化为KASP(Kompetitive allele specific PCR)标记,检测整个RIL群体,进行基因型分析。最后进行RIL群体条锈病成株抗性的QTL分析,在5AL和7AL染色体上发现了2个成株抗性QTL。5A染色体长臂上1个条锈病成株抗性QTL ***-5AL,在所有环境下均存在,可解释6.5%~9.3%的表型变异;***-5AL位于标记Ax-109948955和Ax-108798241之间,连锁距离分别为0.5 cM和1.1 cM。在7A染色体长臂上定位到1个条锈病成株抗性QTL ***-7AL,在2015年和2016年甘谷环境中均稳定存在,分别解释6.2%和7.3%的表型变异;***-7AL位于标记Ax-110361069和Ax-108759561之间,连锁距离分别为0.5 cM和0.7 cM。携带***-5AL和***-7AL抗病等位基因家系的MDS显著低于感病等位基因家系的MDS,表明***-5AL和***-7AL可有效降低条锈病严重度,可应用于小麦抗条锈育种。

关键词：普通小麦条锈病成株抗性 SNP标记连锁分析