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深入基层医院普及神经外科重症管理理念

中国现代神经疾病杂志 2024年第6期24卷 403-406页

作者：魏俊吉常健博中国医学科学院北京协和医学院北京协和医院神经外科 100730

神经外科重症管理在神经外科的发展中发挥越来越重要的作用,不仅为神经外科手术患者提供围手术期生命支持,同时还负责救治中重型脑血管病、颅脑创伤等疾病患者。经过近20年的发展,国内大型三甲医院纷纷成立神经外科重症管理亚专业,但在... 详细信息

神经外科重症管理在神经外科的发展中发挥越来越重要的作用,不仅为神经外科手术患者提供围手术期生命支持,同时还负责救治中重型脑血管病、颅脑创伤等疾病患者。经过近20年的发展,国内大型三甲医院纷纷成立神经外科重症管理亚专业,但在基层医院,神经外科重症管理理念有待进一步推广。本文通过回顾神经外科重症管理亚专业的发展历程,提出增强基层医院诊疗能力、规范专业核心能力标准、落实高质量多学科诊疗模式、完善基本硬件配置,以最终实现神经外科重症管理的规范化。

关键词：神经外科(学) 危重病人医疗基层医院(非MeSH词) 综述

基于物理机制和深度学习的混合模型及应用研究

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中国农村水利水电 2024年第8期 67-72,80页

作者：孙明博闫宝伟常建波邹旖轩古东霖华中科技大学土木与水利工程学院湖北武汉430074 华中科技大学数字流域科学与技术湖北省重点实验室湖北武汉430074

充分利用现代技术手段提高径流预报精度,对流域水旱灾害防御和水库群联合调度具有重要的指导作用。现有深度学习模型存在缺乏模型透明度、物理可解释性差等问题。针对上述难题,将概念水文模型EXP-Hydro嵌入物理递归神经网络P-RNN层,建... 详细信息

充分利用现代技术手段提高径流预报精度,对流域水旱灾害防御和水库群联合调度具有重要的指导作用。现有深度学习模型存在缺乏模型透明度、物理可解释性差等问题。针对上述难题,将概念水文模型EXP-Hydro嵌入物理递归神经网络P-RNN层,建立了耦合物理机制的深度学习混合模型Hybrid-DL,该混合模型采用微分框架实现概念模型与神经网络的深度双向融合,能够同时训练概念模型与神经网络的参数,并以清江上游为例开展了应用研究。结果表明,相较于RNN、EXP-Hydro、BP和SVM模型,Hybrid-DL模型的纳什效率系数NSE分别提升了6.08%、21.01%、37.09%、73.92%,均方根误差RMSE分别降低了10.82%、33.73%、54.70%、95.57%,KGE效率系数分别提升了4.78%、12.68%、26.79%、55.74%,峰值误差TPE分别降低了4.96%、13.12%、252.84%、297.81%。Hybrid-DL模型具有良好的稳健性和适应性,可为清江上游乃至其他流域的径流预报提供可靠的理论工具。

关键词：径流预测物理机制深度学习神经网络单元

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神经内镜硬膜下血肿清除术与钻孔引流术联合尿激酶治疗分隔型慢性硬膜下血肿疗效对比

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中国现代神经疾病杂志 2024年第6期24卷 455-460页

作者：张笑银锐李鹏涛常健博孙思帅魏俊吉中国医学科学院北京协和医学院北京协和医院神经外科100730

目的对比分析神经内镜硬膜下血肿清除术与钻孔引流术联合尿激酶治疗分隔型慢性硬膜下血肿的疗效。方法纳入2022年1月至2023年12月中国医学科学院北京协和医院收治的38例分隔型慢性硬膜下血肿患者,分别予以神经内镜硬膜下血肿清除术(内镜... 详细信息

目的对比分析神经内镜硬膜下血肿清除术与钻孔引流术联合尿激酶治疗分隔型慢性硬膜下血肿的疗效。方法纳入2022年1月至2023年12月中国医学科学院北京协和医院收治的38例分隔型慢性硬膜下血肿患者,分别予以神经内镜硬膜下血肿清除术(内镜组,19例)和钻孔引流术联合尿激酶治疗(钻孔组,19例),计算血肿腔厚度变化率,采用改良Rankin量表(mRS)和Barthel指数(BI)评估神经功能预后和日常生活活动能力,记录术后引流时间、术后住院时间、总住院费用和脑脊液漏发生率。结果内镜组与钻孔组血肿腔厚度变化率差异无统计学意义(t=0.858,P=0.396)。内镜组和钻孔组出院时mRS评分低于入院时(Z=⁃4.116,P=0.000;Z=⁃4.195,P=0.000),BI指数较入院时无明显变化(Z=⁃1.557,P=0.119;Z=⁃0.091,P=0.928);出院时两组mRS评分(Z=⁃0.502,P=0.616)和BI指数(Z=⁃0.853,P=0.394)差异均无统计学意义。内镜组术后引流时间长于钻孔组(t=2.488,P=0.018),但术后住院时间短于钻孔组(t=⁃3.894,P=0.000);而两组总住院费用(t=1.175,P=0.248)和脑脊液漏发生率(Fisher确切概率法:P=0.313)差异无统计学意义。结论分隔型慢性硬膜下血肿无论采取神经内镜硬膜下血肿清除术还是钻孔引流术联合尿激酶治疗均安全、有效,可清除血肿,改善神经功能;神经内镜手术具有术后神经功能恢复更快、术后住院时间更短的优势。

关键词：血肿,硬膜下,慢性神经内窥镜检查引流术尿激酶型纤溶酶原激活物神经外科手术

HYDRODYNAMIC CHARACTERISTICS OF CHINESE STURGEON SPAWNING GROUND IN YANGTZE RIVER

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Journal of Hydrodynamics 2008年第2期20卷 225-230页

作者： YANG Yu YAN Zhong--min chang jian-bo Nanjing Hydraulic Research Institute Nanjing 210029 China State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering Nanjing 210029 China College of Water Conservancy and Hydropower Engineering Hohai University Nanjing 210098 China Institute of Hydro-ecology Wuhan 430072 China

Since the construction of the Gezhouba Dam on the Yangtze River in 1981, it has been found that the Chinese Sturgeon, Acipensor sinensis, performs natural propagation annually in a narrow reach downstream close to the Gezhouba Dam site. This might allow one to better investigate the river hydrodynamic conditions of the Chinese Sturgeon spawning ground. In this article, spatial Kinetic Energy Gradient （KEG） and absolute value of vorticity were computed along the river sections from measured data. The relation between Spawn Density per Unit Area （SDUA） and vorticity strength and between SDUA and KEG were worked out. The Results showed that the vorticity and KEG were both effective parameters for describing the hydrodynamic characteristics of Chinese Sturgeon spawning ground. The Chinese Sturgeons prefer to spawn in the river sections where the value of vorticity strength is larger than 0.4 s^-1 and KEG is larger than 0.029 Jkg^-1m^-1.

关键词： hydrodynamic characteristics Chinese Sturgeon spawning ground vorticity kinetic energy gradient Spawn Densityper Unit Area (SDUA)

非小细胞肺癌患者组织MutS同种组织蛋白2、O6-甲基鸟嘌呤-DNA甲基转移酶表达分析

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实用医院临床杂志 2024年第3期21卷 121-125页

作者：昌建波陈科伍殷小强雷乘强石帅周秋明重庆医科大学附属大足医院/重庆市大足区人民医院重庆402360

目的探讨非小细胞肺癌(NSCLC)患者癌组织MutS同种组织蛋白2(MSH2)、O6-甲基鸟嘌呤-DNA甲基转移酶(MGMT)表达情况及与临床病理参数、预后的关系。方法2021年7月至2022年7月我院收治的96例NSCLC患者,取其手术切除的NSCLC组织标本(NSCLC组... 详细信息

目的探讨非小细胞肺癌(NSCLC)患者癌组织MutS同种组织蛋白2(MSH2)、O6-甲基鸟嘌呤-DNA甲基转移酶(MGMT)表达情况及与临床病理参数、预后的关系。方法2021年7月至2022年7月我院收治的96例NSCLC患者,取其手术切除的NSCLC组织标本(NSCLC组)及距癌边缘3 cm处的癌旁正常组织(对照组)。检测两组MSH2和MGMT的表达水平,分析MSH2和MGMT表达水平与患者临床病理参数及预后的关系。结果与对照组比较,NSCLC组MSH2和MGMT阳性率更低(P<0.05);MSH2阳性与患者分化程度有关(P<0.05);MGMT阳性与患者吸烟史和分化程度有关(P<0.05);与MSH2和MGMT阴性患者比较,阳性患者1年生存率均更高(P<0.05)。结论MSH2和MGMT均在NSCLC组织中存在较低表达,其表达水平与临床病理参数、预后密切相关。

关键词：非小细胞癌癌组织 MutS同种组织蛋白2 O6-甲基鸟嘌呤-DNA甲基转移酶临床病理参数预后

A Novel 3D Gait Model for Subject Identification Robust against Carrying and Dressing Variations

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Computers, Materials & Continua 2024年第7期80卷 235-261页

作者： jian Luo bo Xu Tardi Tjahjadi jian Yi College of Information Science and Engineering Hunan Normal UniversityChangsha410000China School of Engineering University of WarwickCoventryCV47ALUK

Subject identification via the subject’s gait is challenging due to variations in the subject’s carrying and dressing conditions in real-life *** paper proposes a novel targeted 3-dimensional(3D)gait model(3DGait)represented by a set of interpretable 3DGait descriptors based on a 3D parametric body *** 3DGait descriptors are utilised as invariant gait features in the 3DGait recognition method to address object carrying and *** 3DGait recognitionmethod involves 2-dimensional(2D)to 3DGaitdata learningbasedon3Dvirtual samples,a semantic gait parameter estimation Long Short Time Memory(LSTM)network(3D-SGPE-LSTM),a feature fusion deep model based on a multi-set canonical correlation analysis,and SoftMax recognition ***,a sensory experiment based on 3D body shape and pose deformation with 3D virtual dressing is used to fit 3DGait onto the given 2D gait images.3Dinterpretable semantic parameters control the 3D morphing and dressing *** degree measurement determines the semantic descriptors of 2D gait images of subjects with various shapes,poses and ***,using the 2D gait images as input and the subjects’corresponding 3D semantic descriptors as output,an end-to-end 3D-SGPE-LSTM is constructed and ***,body shape,pose and external gait factors(3D-eFactors)are estimated using the 3D-SGPE-LSTM model to create a set of interpretable gait descriptors to represent the 3DGait Model,i.e.,3D intrinsic semantic shape descriptor(3DShape);3D skeleton-based gait pose descriptor(3D-Pose)and 3D dressing with other ***,the 3D-Shape and 3D-Pose descriptors are coupled to a unified pattern space by learning prior knowledge from the *** research on CASIA B,CMU Mobo,TUM GAID and GPJATK databases shows that 3DGait is robust against object carrying and dressing variations,especially under multi-cross variations.

关键词： Gait recognition human identification three-dimensional gait canonical correlation analysis

The unique spontaneous polarization property and application of ferroelectric materials in photocatalysis

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Nano Research 2024年第5期17卷 3571-3585页

作者： Jinghua An chang Xu Lu Li bo Tang College of Chemistry Chemical Engineering and Materials ScienceKey Laboratory of Molecular and Nano ProbesMinistry of EducationCollaborative Innovation Center of Functionalized Probes for Chemical Imaging in University of ShandongInstitute of Molecular and Nano ScienceShandong Normal UniversityJinan 250014China Laoshan Laboratory 168 Wenhai Middle RdAoshanwei JimoQingdao 266237China

The unique spontaneous polarization property of ferroelectric material makes it to be a special catalyst in *** spontaneous polarization property can induce the formation of built-in electric field,which can improve the separation of photoelectrons and holes to affect photocatalytic *** internal electric field induced by spontaneous polarization can be influenced by multiple factors such as the morphology,the concentration of defect,the type of doped heteroatoms,as well as the composition of ***,the preparation method,pretreating temperature,the strength of prepolarized external electric field of ferroelectric-based photocatalysts as well as the strength of external mechanical force or external magnetic field in photocatalytic reactions can influence the photocatalytic effectivity via influencing spontaneous polarization-induced internal electric ***,it is urgently to unveil the mystery of structure-activity relationships for ferroelectric materials-based photocatalysts,which is usually *** this in mind,this review was provided for the role of various complex influencing factors on ferroelectric materials-based photocatalysis based on the latest advancement in the fields of new energy development,environmental *** the beginning,the basic structure and properties of ferroelectric material are ***,popular synthesis methods of ferroelectric-based photocatalysts are *** that,two main mechanisms of ferroelectric photocatalysis are *** research progress of ferroelectric photocatalysis is then given emphatically according to the classification of photocatalytic ***,the problems existing nowadays and the challenges facing in the future on the application of ferroelectric materials-based photocatalysts are outlined in the summary and outlook section.

关键词： spontaneous polarization photocatalysis ferroelectric separation of electrons and holes

High-Performance Recyclable Furan-based Epoxy Resin and Its Carbon Fiber Composites with Dense Hydrogen bonding

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Chinese Journal of Polymer Science 2024年第1期42卷 73-86,I0008页

作者： chang-bo Zhao Lu-Kun Feng Hui Xie Ming-Liang Wang Bing Guo Zhi-Yong Xue Cai-Zhen Zhu jian Xu Advanced Materials Research Institute North China Electric Power UniversityBejing 102206China Institute of Low-Dimensional Materials Genome Initiative College of Chemistry and Environmental EngineeringShenzhen UniversityShenzhen 518060China Chengdu Institute of Organic Chemistry Chinese Academy of SciencesChengdu 610041China School of Science and Shenzhen Key Laboratory of Flexible Printed Electronics Technology and Shenzhen Key Laboratory of Advanced Functional Carbon Materials Research and Comprehensive ApplicationHarbin Institute of TechnologyShenzhen 518055China

The emerging biomass-based epoxy vitrimers hold great potential to fulfill the requirements for sustainable development of *** the existence of dynamic chemical bonds in vitrimers often reduces both the thermal and mechanical properties of epoxy resins, it is challenging to produce recyclable epoxy vitrimers with both excellent mechanical properties and good thermal stability. Herein, a monomer 4-(((5-(hydroxymethyl)furan-2-yl)methylene)amino)phenol(FCN) containing furan ring with potential to form high density of hydrogen bonding among repeating units is designed and copolymerized with glycerol triglycidyl ether to yield epoxy resin(FCN-GTE), which intrinsically has dual hydrogen bond networks, dynamic imine structure and resultant high performance. Importantly, as compared to the BPA-GTE, the FCN-GTE exhibits significantly improved mechanical properties owing to the increased density of hydrogen bond network and physical crosslinking interaction. Furthermore, density functional theory(DFT) calculation and in situ FTIR analysis is conducted to decipher the formation mechanism of hydrogen bond network. In addition, the FCN-GTE possesses superior UV shielding, chemical degradation, and recyclability because of the existence of abundant imine bonds. Notably, the FCN-GTE-based carbon fiber composites could be completely recycled in an amine *** study provides a facile strategy for synthesizing recyclable biomass-based high-performance epoxy vitrimers and carbon fiber composites.

关键词： Furan Hydrogen bond network Dynamic Schiff base Carbon fiber composites Recycling

Typhoon-Induced Ocean Waves and Stokes Drift:A Case Study of Typhoon Mangkhut(2018)

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China Ocean Engineering 2024年第4期38卷 711-724页

作者： WU Zhi-yuan GAO Kai CHEN Jie ZHANG Hao-jian DENG Bin jianG chang-bo LIU Yi-zhuang LYU Zhao YAN Ren School of Hydraulic and Environmental Engineering Changsha University of Science&TechnologyChangsha 410114China Key Laboratory of Water-Sediment Sciences and Water Disaster Prevention of Hunan Province Changsha 410114China State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering Hohai UniversityNanjing 210024China State Key Laboratory of Coastal and Offshore Engineering Dalian University of TechnologyDalian 116024China School of Civil Engineering Hunan University of TechnologyZhuzhou 412007China

Ocean waves and Stokes drift are generated by *** study investigated the characteristics of ocean waves and wave-induced Stokes drift and their effects during Typhoon Mangkhut using European Centre for MediumRange Weather Forecasts(ECMWF)ERA5 datasets and observational *** results revealed that the typhoon generated intense cyclones and huge typhoon waves with a maximum wind speed of 45 m/s,a minimum pressure of955 h Pa,and a maximum significant wave height of 12 *** Stokes drift caused by typhoon waves exceeded 0.6m/s,the Stokes depth scale exceeded 18 m,and the maximum Stokes transport reached 6 m^(2)/*** spatial distribution of 10-m wind speed,typhoon wave height,Stokes drift,Stokes depth,and Stokes transport during the typhoon was highly correlated with the typhoon *** distribution along the typhoon track showed significant zonal asymmetry,with greater intensity on the right side of the typhoon track than on the left *** findings provide important insights into the impact of typhoons on ocean waves and Stokes drift,thus improving our understanding of the interactions between typhoons and the ocean *** study also investigated the contribution of Stokes transport to the total net transport during typhoons using Ekman-Stokes Numbers as a comparative *** results indicated that the ratio of Stokes transport to the total net transport reached up to 50%within the typhoon radius,while it was approximately 30%outside the *** Stokes transport induced by typhoon waves led to divergence in the transport direction,which resulted in upwelling of the lower ocean as a compensation ***,Stokes transport played a crucial role in the vertical mixing of the ocean during *** findings suggested that Stokes transport should be paid more attention to,particularly in high latitude ocean regions,where strong winds can amplify its effects.

关键词： Stokes drift typhoon waves Ekman-Stokes transport vertical mixing Typhoon Mangkhut