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博物馆展览中的观众参与:内涵、方式、困境与对策

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东南文化 2023年第2期 150-156页

作者：常丹婧浙江大学考古与文博系浙江杭州310028

近年来随着博物馆对观众的重视和研究,促进观众的参与成为很多展览策划的目标之一。展览中的观众参与转向表现为观众的观展方式从单一的视觉观察到身体、情感、思维的参与,认知方式从被动的信息接受到主动的探索和思考,观展效果从浅层... 详细信息

近年来随着博物馆对观众的重视和研究,促进观众的参与成为很多展览策划的目标之一。展览中的观众参与转向表现为观众的观展方式从单一的视觉观察到身体、情感、思维的参与,认知方式从被动的信息接受到主动的探索和思考,观展效果从浅层的学习和观赏到深度的学习和对话。博物馆展览中主要有以传播知识和促进理解、以激发对话和建构意义、以鼓励表达和分享观点为目的的观众参与方式。针对当前展览中存在的观众参与困境,博物馆可通过注重以促进观众参与为目的的阐释、观众主体和博物馆引导相结合、发展批判性反思与多视角解读、注重知识性与警惕娱乐化等四方面对策,促使观众参与在展览中的有效实现。

关键词：博物馆展览观众参与

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博物馆学习中的观众参与:概念、特点与对策

东南文化 2021年第5期 169-175页

作者：常丹婧浙江大学考古与文博系浙江杭州310028

当下社会处于迅速发展和转型之中,“参与”是博物馆现代化发展进程中的一个关键词,在互联网的冲击下,传统博物馆势必要向更强的参与性转变,从而满足公众新的需求和期待。在博物馆学习中,观众参与表现为在意识中将自己设想为主动的探索者... 详细信息

当下社会处于迅速发展和转型之中,“参与”是博物馆现代化发展进程中的一个关键词,在互联网的冲击下,传统博物馆势必要向更强的参与性转变,从而满足公众新的需求和期待。在博物馆学习中,观众参与表现为在意识中将自己设想为主动的探索者,在行动中通过体验或操作增进认知。观众参与的特点包括以阐释性展览为参与的场所,以身体、情感和思维为参与的要素,以意义的构建和共享为参与的结果。博物馆可从分众化的展览系统、与观众相连接的展览内容、情境化的沉浸体验、游戏化的参与方式、多感官的体验模式、观众参与表达的平台、群体参观的社交环境七个方面构建参与性的展览环境。

关键词：博物馆博物馆学习展览观众参与观众认知对话

Increase in the variability of terrestrial carbon uptake in response to enhanced future ENSO modulation

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 32-38页

作者： Younong Li Li dan jing Peng Qidong Yang Fuqiang Yang Key Laboratory of Regional Climate-Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina Key Laboratory of Atmospheric Environment and Processes in the Boundary Layer over the Low-Latitude Plateau Region Department of Atmospheric ScienceYunnan UniversityKunmingChina

El Niño-Southern Oscillation(ENSO)is a major driver of climate change in middle and low latitudes and thus strongly influences the terrestrial carbon cycle through land-air *** the ENSO modulation and carbon flux variability are projected to increase in the future,but their connection still needs further *** investigate the impact of future ENSO modulation on carbon flux variability,this study used 10 CMIP6 earth system models to analyze ENSO modulation and carbon flux variability in middle and low latitudes,and their relationship,under different scenarios simulated by CMIP6 *** results show a high consistency in the simulations,with both ENSO modulation and carbon flux variability showing an increasing trend in the *** higher the emissions scenario,especially SSP5-8.5 compared to SSP2-4.5,the greater the increase in *** flux variability in the middle and low latitudes under SSP2-4.5 increases by 30.9%compared to historical levels during 1951-2000,while under SSP5-8.5 it increases by 58.2%.Further analysis suggests that ENSO influences mid-and low-latitude carbon flux variability primarily through *** occurrence may potentially be attributed to the increased responsiveness of gross primary productivity towards regional temperature fluctuations,combined with the intensified influence of ENSO on land surface temperatures.

关键词： Carbon variability ENSO modulation CMIP6 models

MET receptor tyrosine kinase promotes the generation of functional synapses in adult cortical circuits

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Neural Regeneration Research 2025年第5期20卷 1431-1444页

作者： Yuehua Cui Xiaokuang Ma jing Wei chang Chen Neha Shakir Hitesch Guirram Zhiyu Dai Trent Anderson Deveroux Ferguson Shenfeng Qiu Basic Medical Sciences University of Arizona College of Medicine-PhoenixPhoenixAZUSA Department of Medicine University of Arizona College of Medicine-PhoenixPhoenixAZUSA

Loss of synapse and functional connectivity in brain circuits is associated with aging and neurodegeneration,however,few molecular mechanisms are known to intrinsically promote synaptogenesis or enhance synapse *** have previously shown that MET receptor tyrosine kinase in the developing cortical circuits promotes dendritic growth and dendritic spine *** investigate whether enhancing MET in adult cortex has synapse regenerating potential,we created a knockin mouse line,in which the human MET gene expression and signaling can be turned on in adult(10–12 months)cortical neurons through doxycycline-containing *** found that similar to the developing brain,turning on MET signaling in the adult cortex activates small GTPases and increases spine density in prefrontal projection *** findings are further corroborated by increased synaptic activity and transient generation of immature silent *** MET signaling resulted in an increasedα-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/N-methyl-Daspartate(AMPA/NMDA)receptor current ratio,indicative of enhanced synaptic function and *** data reveal that enhancing MET signaling could be an interventional approach to promote synaptogenesis and preserve functional connectivity in the adult *** findings may have implications for regenerative therapy in aging and neurodegeneration conditions.

关键词： aging circuit connectivity cortical circuits molecular mechanisms neural regeneration neurodegeneration synapses

Deciphering the molecular mechanisms of Simiaowan in the treatment of hyperuricemia: in vivo and in silico approaches

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Traditional Medicine Research 2025年第2期10卷 37-54页

作者： Yong-chang Zeng Jun-Hong Wu dan-dan Xu Kang He chang-Qing Liu Li-Fei Song Zheng-Zhi Wu Qian-Qian Jiang Shao-Yu Liang Department of Neurology The First Affiliated Hospital of Shenzhen UniversityShenzhen 518020China Pharmaceutical Department The Affiliated TCM Hospital of Guangzhou Medical UniversityGuangzhou 510000China School of Pharmacy Guizhou University of Traditional Chinese MedicineGuiyang 550025China Guangzhou Zeli Medical Technology Co. Ltd.Guangzhou 510700China

Background:Simiaowan(SMW),a well-known traditional Chinese medicine,has been employed to treat hyperuricemia(HUA)and gout for ***,the bioactive components and underlying mechanisms have not been *** objective of this study was to identify the active components and potential mechanisms of SMW by integrating pharmacological experimentation,serum pharmacochemistry,network pharmacology and molecular ***:HUA rats modelling by high-fat/high-sugar diet and potassium oxonate/adenine oral administration were used to evaluate the pharmacodynamic effects of ***-Q-Exactive-MS/MS was employed to detect the bioactive components present in SMW-containing *** pharmacology and molecular docking were utilized to elucidate the potential targets and underlying ***:SMW effectively ameliorated HUA rats via the inhibition of uric acid(UA)production,promotion of UA excretion,improvement of lipid and glucose metabolic abnormalities,antioxidant,anti-inflammatory and anti-insulin resistance effects.A total of 73 compounds detected in SMW-containing serum were identified as potential active components,with alkaloids,flavonoids,organic acids,and terpenoids emerging as the primary active *** 203 corresponding targets were obtained as SMW anti-HUA/gout targets,which mainly participated in apoptosis,insulin resistance,TNF,PI3K-Akt,HIF-1,NF-κB,MAPK,IL-17 and TLR signaling *** docking indicated that active compounds(***,phellodendrine,quercetin,formononetin,ferulic acid)had superior binding abilities to the key targets(*** carrier family 22 member 12(URAT1),solute carrier family 22 member 6(OAT1),ATP-binding cassette sub-family G member 2(ABCG2),solute carrier family 2,facilitated glucose transporter member 9(GLUT9),xanthine dehydrogenase/oxidase(XDH),transcription factor p65(RELA),toll-like receptor 4(TLR4),prostaglandin G/H synthase 2(PTGS2),caspase-3(CASP3),insulin(INS)).Conclusion:S

关键词： hyperuricemia network pharmacology serum pharmacochemistry Simiaowan UPLC-Q-Exactive-MS/MS

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新疆出口商品结构合理度的实证研究

新疆职业大学学报 2012年第6期20卷 18-22页

作者：常丹静龚新蜀石河子大学经济与管理学院新疆乌鲁木齐832000

以2002、2007年新疆投入产出表为基础,采用由投入产出模型推导出来的出口商品结构合理度指数来分析新疆出口商品结构的合理性问题。研究结果表明,从2002年到2007年新疆出口商品结构的合理性呈恶化的趋势。为了使新疆出口商品结构更加合... 详细信息

以2002、2007年新疆投入产出表为基础,采用由投入产出模型推导出来的出口商品结构合理度指数来分析新疆出口商品结构的合理性问题。研究结果表明,从2002年到2007年新疆出口商品结构的合理性呈恶化的趋势。为了使新疆出口商品结构更加合理,应优先扩大造纸印刷及文教体育用品制造业、金属制品业、电气机械及器材制造业、建筑业、交通运输设备制造业等部门的出口比重。

关键词：新疆出口商品结构投入产出

Increase in the variability of terrestrial carbon uptake in response to enhanced future ENSO modulation

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Atmospheric and Oceanic Science Letters 2025年第01期 34-40页

作者： Younong Li Li dan jing Peng Qidong Yang Fuqiang Yang Key Laboratory of Regional Climate-Environment for Temperate East Asia Institute of Atmospheric Physics Chinese Academy of Sciences Key Laboratory of Atmospheric Environment and Processes in the Boundary Layer over the Low-Latitude Plateau Region Department of Atmospheric Science Yunnan University

ENSO是中低纬度地区气候系统的主要驱动因素,对陆地碳循环有重要影响.本研究基于10个CMIP6地球系统模式,分析了不同情景下ENSO变率与中低纬度地区总初级生产力变率的关系.结果显示,未来ENSO变率和总初级生产力变率在未来多数模式均显示... 详细信息

ENSO是中低纬度地区气候系统的主要驱动因素,对陆地碳循环有重要影响.本研究基于10个CMIP6地球系统模式,分析了不同情景下ENSO变率与中低纬度地区总初级生产力变率的关系.结果显示,未来ENSO变率和总初级生产力变率在未来多数模式均显示为增加.在未来情境下(2051-2100年),中低纬度地区的总初级生产力变率较历史时期(1951–2000年)增加了30.9%(SSP2-4.5), 58.2%(SSP5-8.5).进一步分析表明, ENSO主要通过温度影响中低纬度碳通量变率.这种现象可能归因于总初级生产力对温度的响应增强,以及ENSO对陆地表面温度的影响.

关键词：总初级生产力 ENSO变率 CMIP6

数字经济赋能养老服务业跨越“低水平均衡陷阱”

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河北学刊 2025年第1期45卷 152-161页

作者：夏杰长罗敬蔚中国社会科学院财经战略研究院中央财经大学法学院

中国养老服务业正面临低水平需求与高成本供给之间的矛盾,这直接导致养老服务业陷入“低水平均衡陷阱”。数字经济在优化养老资源配置、降低养老服务成本和完善养老生态系统等方面发挥了重要作用,是跨越养老服务业“低水平均衡陷阱”的... 详细信息

中国养老服务业正面临低水平需求与高成本供给之间的矛盾,这直接导致养老服务业陷入“低水平均衡陷阱”。数字经济在优化养老资源配置、降低养老服务成本和完善养老生态系统等方面发挥了重要作用,是跨越养老服务业“低水平均衡陷阱”的重要力量。借力数字经济推动养老服务实现高水平均衡,进而实现养老服务业高质量发展,需要综合施策:适当延长老年群体工作年限;对老年人口进行数字技术培训,助力他们跨越数字鸿沟;利用数字技术优化养老服务的资源配置;多渠道降低养老服务业成本;提升从业人员数字素养。

关键词： “低水平均衡陷阱” 老龄化数字经济养老服务业

Early intervention with Didang decoction delays macrovascular lesions in diabetic rats through regulating AMP-activated protein kinase signaling pathway

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Chinese Journal of Natural Medicines 2017年第11期15卷 847-854页

作者： REN dan-dan LI jing chang Bai LI Chun-Shen YANG Ju-Hong Metabolic Diseases Hospital Tianjin Medical University Tianjin 300070 China Tanggu Dahua Hospital Tianjin Coastal New Area Tianjin 300455 China Tianjin University of Traditional Chinese Medicine Tianjin 300193 China

The study aimed to investigate the intervening role of Didang decoction(DDD) at different times in macrovascular endothelial defense function, focusing on its effects on the AMP-activated protein kinase(AMPK) signaling pathway. The effects of DDD on mitochondrial energy metabolism were also investigated in rat aortic endothelial cells(RAECs). Type 2 diabetes were induced in rats by streptozotocin(STZ) combined with high fat diet. Rats were randomly divided into non-intervention group, metformin group, simvastatin group, and early-, middle-, late-stage DDD groups. Normal rats were used as control. All the rats received 12 weeks of intervention or control treatment. Western blots were used to detect the expression of AMP-activated protein kinase α1(AMPKα1) and peroxisome proliferator-activated receptor 1α(PGC-1α). changes in the intracellular AMP and ATP levels were detected with ELISA. Real-time-PCR was used to detect the m RNA level of caspase-3, endothelial nitric oxide synthase(eNOS), and Bcl-2. Compared to the diabetic non-intervention group, a significant increase in the expression of AMPKα1 and PGC-1α were observed in the early-stage, middle-stage DDD groups and simvastatin group(P< 0.05). The levels of Bcl-2, eNOS, and ATP were significantly increased(P<0.05), while the level of AMP and caspase-3 were decreased(P< 0.05) in the early-stage DDD group and simvastatin group. Early intervention with DDD enhances mitochondrial energy metabolism by regulating the AMPK signaling pathway and therefore may play a role in strengthening the defense function of large vascular endothelial cells and postpone the development of macrovascular diseases in diabetes.

关键词： Didang decoction Caspase-3 AMPK Endothelial cells PGC-1α