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Characteristic findings of malignant melanoma in the sinonasal cavity on magnetic resonance imaging

Chinese Medical Journal 2012年第20期125卷 3687-3691页

作者： XU Qing-gang FU li-ping WANG Zhen-chang XIAN Jun-fang HE li-yan ZHANG zheng-yu liU cheng-yao Department of Ratiology Department of Otorhinolaryngology Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Department of Nuclear Medicine General Hospital of the Chinese People's Liberation Army and Military Medical Postgraduate CollegeBeijing 100853China

Background Malignant sinonasal melanoma （MSM） is a rare tumor with a perplexing signal intensity due to variable histopathologic components. This study was undertaken to delineate its MR imaging features. Methods MR imaging findings of 10 patients （6 women and 4 men, mean age 61.3 years old） with pathologically confirmed MSM were retrospectively reviewed. The location, size, signal intensity, enhancement, and internal imaging characteristics of all tumors were evaluated. Signal intensity and degree of enhancement was graded in comparison with the gray matter and adjacent muscle uptake, respectively. Results There were 8 tumors that were pathologically confirmed to contain melanin. Compared to gray matter of the brain, 7 of them demonstrated hyperintensity on T1WI and 6 （6/7） showed hypointensity on T2Wl. There was multiple linear, dark-signal intensity on T2Wl within the mass in 9 of the 10 patients＇ tumors. Evaluated with gadolinium-enhanced imaging, all 10 patients showed moderate enhancement within the areas that were isointense in the lesion on pregadolinium TlWl. Moreover, some parts which displayed hyperintensity on TlWl within the tumors of 7 patients showed mild enhancement that was similar to muscle on a time-intensity curve （TIC）. Conclusions MSM shows characteristic MR signal intensity （hyperintensity on TlWl and the linear, low-signal intensity on T2Wl）, which may provide valuable information for clinical diagnosis. Together with conventional MRI, TIC may be useful for indicating pleomorphic patterns of MSM.

关键词： malignant melanoma " nasal cavity " magnetic resonance imaging

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具有腔内光放大的单共振光参量振荡器

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物理学报 2005年第10期54卷 4754-4760页

作者：邓诚先李正佳朱长虹激光技术国家重点实验室华中科技大学武汉430074

推导了描述稳态运行,具有腔内光放大的环形腔单共振光参量振荡器(ICOASRO)的功率特性的高斯光束理论.在这种结构的单共振光参量振荡器(SRO)中,适当地选择光放大器的参数,可以很大程度地降低单共振光参量振荡器的抽运阈值.在平均场近似... 详细信息

推导了描述稳态运行,具有腔内光放大的环形腔单共振光参量振荡器(ICOASRO)的功率特性的高斯光束理论.在这种结构的单共振光参量振荡器(SRO)中,适当地选择光放大器的参数,可以很大程度地降低单共振光参量振荡器的抽运阈值.在平均场近似下无二阶非线性交叉耦合作用的具有腔内光放大的环形腔单共振光参量振荡器的工作范围分成四个工作区域,且存在最小的单共振光参量振荡器的抽运阈值.文中的分析考虑了作为光放大器的激光增益介质的端面抽运特性,考虑了一般化单共振光参量振荡器的特性.

关键词：单共振光参量振荡器光放大阈值光参量振荡器光放大器共振腔内功率特性端面抽运二阶非线性

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Estimation of Battery State of Health Using Back Propagation Neural Network

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Computer Aided Drafting,Design and Manufacturing 2014年第1期24卷 60-63页

作者： chang cheng liU zheng-yu HUANG Ye-wei WEI De-qi ZHANG li ATECH Automotive Wuhu Co. Ltd School of Machinery and Automobile Engineering Hefei University of Technology Engineering Research Center of Safety-critical Industry Measure and Control Technology of Ministry of Education

100 pieces of 26650-type lithium iron phosphate（liFePO4） batteries cycled with a fixed charge and discharge rate are tested, and the influence of the battery internal resistance and the instantaneous voltage drop at the start of discharge on the state of health（SOH） is discussed. A back propagation（BP） neural network model using additional momentum is built up to estimate the state of health of li-ion batteries. The additional 10 pieces are used to verify the feasibility of the proposed method. The results show that the neural network prediction model have a higher accuracy and can be embedded into battery management system（BMS） to estimate SOH of liFePO4 li-ion batteries.

关键词： liFePO4 battery state of health neural network prediction model

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Evidence for particle acceleration approaching PeV energies in the W51 complex

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Science Bulletin 2024年第18期69卷 2833-2841页

作者： LHAASO Collaboration Zhen Cao F.Aharonian Axikegu Y.X.Bai Y.W.Bao D.Bastieri X.J.Bi Y.J.Bi W.Bian A.V.Bukevich Q.Cao W.Y.Cao Zhe Cao J.chang J.F.chang A.M.Chen E.S.Chen H.X.Chen liang Chen lin Chen Long Chen M.J.Chen M.L.Chen Q.H.Chen S.Chen S.H.Chen S.Z.Chen T.L.Chen Y.Chen N.cheng Y.D.cheng M.Y.Cui S.W.Cui X.H.Cui Y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai Danzengluobu X.Q.Dong K.K.Duan J.H.Fan Y.Z.Fan J.Fang J.H.Fang K.Fang C.F.Feng H.Feng L.Feng S.H.Feng X.T.Feng Y.Feng Y.L.Feng S.Gabici B.Gao C.D.Gao Q.Gao W.Gao W.K.Gao M.M.Ge L.S.Geng G.Giacinti G.H.Gong Q.B.Gou M.H.Gu F.L.Guo X.L.Guo Y.Q.Guo Y.Y.Guo Y.A.Han M.Hasan H.H.He H.N.He J.Y.He Y.He Y.K.Hor B.W.Hou C.Hou X.Hou H.B.Hu Q.Hu S.C.Hu D.H.Huang T.Q.Huang W.J.Huang X.T.Huang X.Y.Huang Y.Huang X.L.Ji H.Y.Jia K.Jia K.Jiang X.W.Jiang Z.J.Jiang M.Jin M.M.Kang I.Karpikov D.Kuleshov K.Kurinov B.B.li C.M.li cheng li Cong li D.li F.li H.B.li H.C.li Jian li Jie li K.li S.D.li W.L.li W.L.li X.R.li Xin li Y.Z.li Zhe li Zhuo li E.W.liang Y.F.liang S.J.lin B.liu C.liu D.liu D.B.liu H.liu H.D.liu J.liu J.L.liu M.Y.liu R.Y.liu S.M.liu W.liu Y.liu Y.N.liu Q.Luo Y.Luo H.K.Lv B.Q.Ma L.L.Ma X.H.Ma J.R.Mao Z.Min W.Mitthumsiri H.J.Mu Y.C.Nan A.Neronov L.J.Ou P.Pattarakijwanich Z.Y.Pei J.C.Qi M.Y.Qi B.Q.Qiao J.J.Qin A.Raza D.Ruffolo A.Sáiz M.Saeed D.Semikoz L.Shao O.Shchegolev X.D.Sheng F.W.Shu H.C.Song Yu.V.Stenkin V.Stepanov Y.Su D.X.Sun Q.N.Sun X.N.Sun Z.B.Sun J.Takata P.H.T.Tam Q.W.Tang R.Tang Z.B.Tang W.W.Tian C.Wang C.B.Wang G.W.Wang H.G.Wang H.H.Wang J.C.Wang Kai Wang Kai Wang L.P.Wang L.Y.Wang P.H.Wang R.Wang W.Wang X.G.Wang X.Y.Wang Y.Wang Y.D.Wang Y.J.Wang Z.H.Wang Z.X.Wang Zhen Wang zheng Wang D.M.Wei J.J.Wei Y.J.Wei T.Wen C.Y.Wu H.R.Wu Q.W.Wu S.Wu X.F.Wu Y.S.Wu S.Q.Xi J.Xia G.M.Xiang D.X.Xiao G.Xiao Y.L.Xin Y.Xing D.R.Xiong Z.Xiong D.L.Xu R.F.Xu R.X.Xu W.L.Xu L.Xue D.H.Yan J.Z.Yan T.Yan C.W.Yang C.Y.Yang F.Yang F.F.Yang L.L.Yang M.J.Yang R.Z.Yang W.X.Yang Y.H.Yao Z.G.Yao L.Q.Yin N.Yin X.H.You Z.Y.You Y.H.Yu Q.Yuan H.Yue H.D.Zeng T.X.Zeng W.Zeng M.Zha B.B.Zhang F.Zhang H.Zhang 不详 Key Laboratory of Particle Astrophysics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduChina Dublin Institute for Advanced Studies 31 Fitzwilliam Place2 DublinIreland Max-Planck-Institut for Nuclear Physics P.O.Box 103980Heidelberg 69029Germany School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Institute for Nuclear Research of Russian Academy of Sciences Moscow 117312Russia Hebei Normal University Shijiazhuang 050024China University of Science and Technology of China Hefei 230026China State Key Laboratory of Particle Detection and Electronics China Key Laboratory of Dark Matter and Space Astronomy&Key Laboratory of Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Research Center for Astronomical Computing Zhejiang LaboratoryHangzhou 311121China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China School of Physics and Astronomy Yunnan UniversityKunming 650091China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Physics and Astronomy(Zhuhai)&School of Physics(Guangzhou)&Sino-French Institute of Nuclear Engineering and Technology(Zhuhai) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275GuangdongChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China APC UniversitéParis Cité

Theγ-ray emission from the W51 complex is widely acknowledged to be attributed to the interaction between the cosmic rays(CRs)accelerated by the shock of supernova remnant(SNR)W51C and the dense molecular clouds in the adjacent star-forming region,***,the maximum acceleration capability of W51C for CRs remains *** on observations conducted with the Large High Altitude Air Shower Observatory(LHAASO),we report a significant detection ofγrays emanating from the W51 complex,with energies from 2 to 200 *** LHAASO measurements,for the first time,extend theγ-ray emission from the W51 complex beyond 100 TeV and reveal a significant spectrum bending at tens of *** combining the"π^(0)-decay bump"featured data from Fermi-LAT,the broadbandγ-ray spectrum of the W51 region can be well-characterized by a simple pp-collision *** observed spectral bending feature suggests an exponential cutoff at~400 TeV or a power-law break at~200 TeV in the CR proton spectrum,most likely providing the first evidence of SNRs serving as CR accelerators approaching the PeV ***,two young star clusters within W51B could also be theoretically viable to produce the most energeticγrays observed by *** findings strongly support the presence of extreme CR accelerators within the W51 complex and provide new insights into the origin of Galactic CRs.

关键词： UHE c-ray Cosmic rays SNR W51C Star clusters

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Superconductivity in Topological Semimetal θ-TaN at High Pressure

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Chinese Physics Letters 2019年第8期36卷 88-93页

作者： Ya-Ting Jia Jian-Fa Zhao Si-Jia Zhang Shuang Yu Guang-Yang Dai Wen-Min li Lei Duan Guo-Qiang Zhao Xian-cheng Wang Xu zheng Qing-Qing liu You-Wen Long Zhi li Xiao-Dong li Hong-Ming Weng Run-Ze Yu Ri-cheng Yu chang-Qing Jin Institute of Physics Chinese Academy of SciencesBeijing100190 School of Physics University of Chinese Academy of SciencesBeijing100190 Songshan Lake Materials Laboratory Guangdong523808 School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing210094 Institute of High Energy Physics Chinese Academy of SciencesBeijing100049

Recently,θ-TaN was proposed to be a topological semimetal with a new type of triply degenerate nodal ***,we report studies of pressure dependence of transport,Raman spectroscopy and synchrotron x-ray diffraction on θ-TaN up to 61 *** find that θ-TaN becomes superconductive above 24.6 GPa with Tc at 3.1 *** θ-TaN is of n-type carrier nature with carrier density about 1.1 × 1020/cm3 at 1.2 GPa and 20 K, while the carrier density increases with the pressure and saturates at about 40 GPa in the measured ***,there is no crystal structure transition with pressure up to 39 GPa,suggesting the topological nature of the pressure induced superconductivity.

关键词： High Pressure Superconductivity Semimetal

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Diagnosis and treatment of autoimmune pancreatitis: experience with 100 patients

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Hepatobiliary & Pancreatic Diseases International 2014年第6期13卷 642-648页

作者： Lei Xin Yuan-Xiang He Xiao-Fei Zhu Qun-Hua Zhang liang-Hao Hu Duo-Wu Zou Zhen-Dong Jin Xue-Jiao chang Jian-Ming zheng changhai Hospital Second Military Medical University chang-Jing Zuo cheng-Wei Shao Gang Jin Zhuan liao Zhao-Shen li Department of Gastroenterology Changhai Hospital Second Military Medical University Department of Surgical Oncology Chinese PLA General Hospital Department of General Surgery Huashan Hospital Fudan University Department of Pathology Changhai Hospital Second Military Medical University Department of Nuclear Medicine Changhai Hospital Second Military Medical University Department of Radiology Changhai Hospital Second Military Medical University Department of General Surgery Changhai Hospital Second Military Medical University

BACKGROUND： Autoimmune pancreatitis （ALP） is increasingly recognized as a unique subtype of pancreatitis. This study aimed to analyze the diagnosis and treatment of AIP patients from a tertiary care center in China. METHODS： One hundred patients with AIP who had been treated from January 2005 to December 2012 in our hospital were enrolled in this study. We retrospectively reviewed the data of clinical manifestations, laboratory tests, imaging examinations, pathological examinations, treatment and outcomes of the patients. RESULTS： The median age of the patients at onset was 57 years （range 23-82） with a male to female ratio of 8.1：1. The common manifestations of the patients included obstructive jaundice （49 patients, 49.0%）, abdominal pain （30, 30.0%）, and acute pancreatitis （11, 11.0%）. Biliary involvement was one of the most extrapancreatic manifestations （64, 64.0%）. Fifty-six （56.0%） and 43 （43.0%） patients were classified into focal- type and diffuse-type respectively according to the imaging examinations. The levels of serum IgG and IgG4 were elevated in 69.4% （43/62） and 92.0% （69/75） patients. Pathological analysis of specimens from 27 patients supported the diagnosis of lymphoplasmacytic sclerosing pancreatitis, and marked （〉10 ceUs/HPF） IgG4 positive cells were found in 20 （74.1%） *** treatment and surgery as the main initial treatments were given to 41 （41.0%） and 28 （28.0%） patients, respectively. The remission rate after the initial treatment was 85.0%. Steroid was given as the treatment after relapse in most of the patients and the total remission rate at the end of follow-up was 96.0%. CONCLUSIONS： Clinical manifestations, laboratory tests, imaging and pathology examinations in combination could increase the diagnostic accuracy of AIP. Steroid treatment with an initial dose of 30 or 40 mg prednisone is effective and safe in most patients with AIP.

关键词： autoimmune pancreatitis immunoglobulin G4 steroid treatment

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High spindle and kinetochore-associated complex subunit-3 expression predicts poor prognosis and correlates with adverse immune infiltration in hepatocellular carcinoma

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世界胃肠外科杂志:英文版(电子版) 2023年第8期15卷 1600-1614页

作者： lin-lin zheng Ya-Ru Wang Zhen-Rong liu Zhi-Hao Wang chang-cheng Tao Yong-Gang Xiao Kai Zhang An-Ke Wu Hai-Yang li Jian-Xiong Wu Ting Xiao Wei-Qi Rong Department of Hepatobiliary Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China State Key Laboratory of Molecular Oncology Department of Etiology and CarcinogenesisNational Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Department of Hepatobiliary Hernia Surgery Liaocheng Dongcangfu People's HospitalLiaocheng 252000Shandong ProvinceChina The Second Ward of Hepatobiliary Surgery Qianxinan People's HospitalXingyi 562400Guizhou ProvinceChina Department of Interventional Therapy Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjin's Clinical Research Center for CancerTianjin 300000China

BACKGROUND Spindle and kinetochore-associated complex subunit 3(SKA3)is a malignancyassociated gene that plays a critical role in the regulation of chromosome separation and cell ***,the molecular mechanism through which SKA3 regulates tumor cell proliferation in hepatocellular carcinoma(HCC)has not been fully *** To investigate the molecular mechanisms underlying the role of SKA3 in *** SKA3 expression,clinicopathological,and survival analyses were performed using multiple public database platforms,and the results were verified by Western blot and immunohistochemistry staining using collected clinical *** enrichment analyses were performed to evaluate the biological functions and molecular mechanisms of SKA3 in ***,the Tumor Immune Estimation Resource and single-sample Gene Set Enrichment Analysis(ssGSEA)algorithms were utilized to investigate the abundance of tumor-infiltrating immune cells in *** response to chemotherapeutic drugs was evaluated by the R package“pRRophetic”.RESULTS We found that upregulated SKA3 expression was significantly correlated with poor prognosis in patients with *** Cox regression analysis indicated that SKA3 was an independent risk factor for *** revealed that SKA3 expression may facilitate proliferation and migratory processes by regulating the cell cycle and DNA ***,patients with high SKA3 expression had significantly decreased ratios of CD8+T cells,natural killer cells,and dendritic *** sensitivity analysis showed that the high SKA3 group was more sensitive to sorafenib,sunitinib,paclitaxel,doxorubicin,gemcitabine,and *** High SKA3 expression led to poor prognosis in patients with HCC by enhancing HCC proliferation and repressing immune cell infiltration surrounding ***3 may be used as a biomarker for poor prognosis and as a therapeutic target in HCC.

关键词： Spindle and kinetochore-associated protein 3 Hepatocellular carcinoma Prognosis Immune infiltration cells

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粘弹性材料中裂纹增长的仿真研究

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机械强度 2007年第5期29卷 827-830页

作者：李成常向前郑艳萍郑州大学机械工程学院郑州450001 黄委会水科院工程力学研究所郑州450003

针对含裂纹的粘弹性材料结构,根据粘弹性断裂理论分析裂纹增长的条件。建立基于裂纹周围小范围滑动的计算模型,采用Laplace转换关系,可以将粘弹性边界值问题变为弹性边界值问题处理,在所得到的表达式中并不直接含有弹性常数,因此它能较... 详细信息

针对含裂纹的粘弹性材料结构,根据粘弹性断裂理论分析裂纹增长的条件。建立基于裂纹周围小范围滑动的计算模型,采用Laplace转换关系,可以将粘弹性边界值问题变为弹性边界值问题处理,在所得到的表达式中并不直接含有弹性常数,因此它能较好地描述粘弹性问题。得到描述含裂纹粘弹性材料在不同的时间裂纹增长情况的裂纹增长速率以及蠕变时间解析解。并按照所建立的计算模型对不同的材料性质、不同的裂纹尖端应力强度因子、不同的外载荷对裂纹增长速率及蠕变时间的影响进行探讨。

关键词：粘弹性材料裂纹仿真裂纹增长速率蠕变时间

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拉扭组合轴圆周表面裂纹应力强度因子仿真

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农业机械学报 2008年第2期39卷 167-169,124页

作者：李成常向前郑艳萍郑州大学机械工程学院郑州市450001 黄河水利委员会水科院工程力学研究所郑州市450003

针对轴的圆周表面裂纹,采用弹性断裂理论和复变函数理论建立了计算模型。根据圆周表面裂纹应力强度因子解析计算方法仿真研究了裂纹深度、载荷类型、圆轴直径对应力强度因子的影响。得到了不同情况下的应力强度因子。给出了应力强度因... 详细信息

针对轴的圆周表面裂纹,采用弹性断裂理论和复变函数理论建立了计算模型。根据圆周表面裂纹应力强度因子解析计算方法仿真研究了裂纹深度、载荷类型、圆轴直径对应力强度因子的影响。得到了不同情况下的应力强度因子。给出了应力强度因子随裂纹深度变化的规律。并对轴受拉力、扭矩作用情况下的应力强度因子进行了比较。

关键词：拉扭组合轴圆周表面裂纹应力强度因子仿真

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Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer:final overall survival analysis of the EMERGING-CTONG 1103 randomised phase II trial

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Signal Transduction and Targeted Therapy 2023年第3期8卷 1310-1317页

作者： Wen-Zhao Zhong Hong-Hong Yan Ke-Neng Chen Chun Chen Chun-Dong Gu Jun Wang Xue-Ning Yang Wei-Min Mao Qun Wang Gui-Bin Qiao Ying cheng lin Xu chang-li Wang Ming-Wei Chen Xiao-zheng Kang Wan-Pu Yan Ri-Qiang liao Jin-Ji Yang Xu-Chao Zhang Si-Yang liu Qing zhou Yi-Long Wu Guangdong Provincial People’s Hospital Guangdong Academy of Medical Sciences510080 GuangzhouChina Peking University Cancer Hospital and Institute 100142 BeijingChina Fujian Medical University Union Hospital 350001 FuzhouChina First Affiliated Hospital of Dalian Medical University 116011 DalianChina Peking University People’s Hospital 100044 BeijingChina Zhejiang Cancer Hospital 310022 HangzhouChina Zhongshan Hospital 200032 ShanghaiChina Guangzhou liuhuaqiao Hospital 510000 GuangzhouChina Jilin Provincial Tumor Hospital 130012 ChangchunChina Jiangsu Cancer Institute and Hospital 210009 NanjingChina Tianjin Medical University Cancer Institute and Hospital 300060 TianjinChina First Affiliated Hospital of Xi’an Jiaotong University 710061 Xi’anChina

EMERGING-CTONG 1103 showed improved progression-free survival(PFS)with neoadjuvant erlotinib *** for patients harbouring EGFR sensibility mutations and R0 resected stage IIIA-N2 non-small cell lung cancer(NSCLC)(NCT01407822).Herein,we report the final *** patients were randomly allocated 1:1 to the erlotinib group(150 mg/day orally;neoadjuvant phase for 42 days and adjuvant phase to 12 months)or to the GC group(gemcitabine 1250 mg/m2 plus cisplatin 75 mg/m2 intravenously;2 cycles in neoadjuvant phase and 2 cycles in adjuvant phase).Objective response rate(ORR),complete pathologic response(pCR),PFS,and overall survival(OS)were assessed along with *** hoc analysis was performed for subsequent treatments after disease *** investigated 72 patients(erlotinib,n=37;GC,n=35),the median follow-up was 62.5 *** median OS was 42.2 months(erlotinib)and 36.9 months(GC)(hazard ratio[HR],0.83;95%confidence interval[CI],0.47-1.47;p=0.513).The 3-and_(5-y)ear OS rates were 58.6%and 40.8%with erlotinib and 55.9%and 27.6%with GC(p_(3-y)=0.819,p_(5-y)=0.252).Subsequent treatment was administered in 71.9%and 81.8%of patients receiving erlotinib and GC,respectively;targeted therapy contributed mostly to OS(HR,0.35;95%CI,0.18-0.70).After disease progression,the ORR was 53.3%,and the median PFS was 10.9 months during the EGFR-TKI *** postoperative therapy,grade 3 or 4 adverse events(AEs)were 13.5%in the erlotinib group and 29.4%in the GC *** serious adverse events were *** exhibited clinical feasibility for resectable IIIA-N2 NSCLC over chemotherapy in the neoadjuvant setting.

关键词： neoadjuvant cisplatin chemotherapy

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