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Mechanisms of fracture propagation from multi-cluster using a phase field based HMD coupling model in fractured reservoir

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Petroleum Science 2024年第3期21卷 1829-1851页

作者： Yun-Jin Wang Bo Wang Hang Su tu chang Ren-Cheng Dong Li-Zhe Li Wei-Yu Tang Ting-Xue Jiang Fu-Jian Zhou State Key Laboratory of Petroleum Resources and Engineering China University of Petroleum-BeijingBejing2249China China University of Petroleum-Beijing at Karamay Karamay834000XinjiangChina China National Oil and Gas Exploration and Development Corporation Ltd. Beijing100034China University of Texas at Austin United States SINOPEC Research Institute of Petroleum Engineering Beijing100101China

Natural fractures(NFs)are common in shale and tight reservoirs,where staged multi-cluster fracturing of horizontal wells is a prevalent technique for reservoir *** NFs and stress interference are recognized as significant factors affecting hydraulic fracture(HF)propagation,the combined influence of these factors remains poorly *** address this knowledge gap,a novel coupled hydromechanical-damage(HMD)model based on the phase field method is developed to investigate the propagation of multi-cluster HFs in fractured *** comprehensive energy functional and control functions are established,while incorporating dynamic fluid distribution between multiple perforation clusters and refined changes in rock mechanical parameters during hydraulic *** HMD coupled multi-cluster HF propagation model investigates various scenarios,including single HF and single NF,reservoir heterogeneity,single HF and NF clusters,and multi-cluster HFs with NF *** results show that the HMD coupling model can accurately capture the impact of approach angle(θ),stress difference and cementation strength on the interaction of HF and *** criterion of the open and cross zones is not *** NF angle(a)is not a decisive parameter to discriminate the *** to the relationship between approach angle(θ)and NF angle(a),the contact relationship of HF can be divided into three categories(θ=a,θa).The connected NF can increase the complexity of HF by inducing it to form branch fracture,resulting in a fractal dimension of HF as high as2.1280 at angles of±45°.Inter-fracture interference from the heel to the toe of HF shows the phenomenon of no,strong and weak ***,under the influence of NFs,distant HFs from the injection can become dominant ***,as a gradually increases,inter-fracture stress interference becomes the primary factor influencing HF propagation,gradually superseding the dominance of NF

关键词： HMD coupling Phase field Natural fracture Flow distribution Hydraulic fracturing Inter-fracture interference

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OAAFormer:Robust and Efficient Point Cloud Registration Through Overlapping-Aware Attention in Transformer

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Journal of Computer Science & Technology 2024年第4期39卷 755-770页

作者： Jun-Jie Gao Qiu-Jie Dong Rui-An Wang Shuang-Min Chen Shi-Qing Xin chang-He tu Wenping Wang School of Computer Science and Technology Shandong UniversityQingdao 266237China School of Information and Technology Qingdao University of Science and TechnologyQingdao 266061China College of Engineering Texas A&M UniversityTexasTX 77843U.S.A.

In the domain of point cloud registration,the coarse-to-fine feature matching paradigm has received significant attention due to its impressive *** paradigm involves a two-step process:first,the extraction of multilevel features,and subsequently,the propagation of correspondences from coarse to fine ***,this approach faces two notable ***,the use of the Dual Softmax operation may promote one-to-one correspondences between superpoints,inadvertently excluding valuable ***,it is crucial to closely examine the overlapping areas between point clouds,as only correspondences within these regions decisively determine the actual *** these issues,we propose OAAFormer to enhance correspondence *** the one hand,we introduce a soft matching mechanism to facilitate the propagation of potentially valuable correspondences from coarse to fine *** the other hand,we integrate an overlapping region detection module to minimize mismatches to the greatest extent ***,we introduce a region-wise attention module with linear complexity during the fine-level matching phase,designed to enhance the discriminative capabilities of the extracted *** on the challenging 3DLoMatch benchmark demonstrate that our approach leads to a substantial increase of about 7%in the inlier ratio,as well as an enhancement of 2%-4%in registration ***,to accelerate the prediction process,we replace the Conventional Random Sample Consensus(RANSAC)algorithm with the selection of a limited yet representative set of high-confidence correspondences,resulting in a 100 times speedup while still maintaining comparable registration performance.

关键词： point cloud registration coarse-to-fine overlapping region feature matching Transformer

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负压条件对T2/Q235爆炸焊接复合板界面的影响

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火炸药学报 2024年第1期47卷 64-71页

作者：汪泉胡程谢守冬李孝臣李志敏涂唱畅朱群龙杨锐安徽理工大学化工与爆破学院安徽淮南232001 安徽理工大学安全科学与工程学院安徽淮南232001 安徽理工大学土木建筑学院安徽淮南232001 宏大爆破工程集团有限责任公司广东广州510000

为了探究负压条件对T2/Q235爆炸焊接复合板界面的影响,选用硅藻土敏化的低爆速粉状乳化炸药作为焊接专用药,T2为覆板,Q235为基板分别在100、60、20kPa环境压力下进行爆炸焊接试验;采用金相分析等方法研究了复合界面的形貌特征和元素组分... 详细信息

为了探究负压条件对T2/Q235爆炸焊接复合板界面的影响,选用硅藻土敏化的低爆速粉状乳化炸药作为焊接专用药,T2为覆板,Q235为基板分别在100、60、20kPa环境压力下进行爆炸焊接试验;采用金相分析等方法研究了复合界面的形貌特征和元素组分,采用数值模拟进一步揭示了负压爆炸焊接机理。结果表明,负压条件会增大粉状乳化炸药的装药密度,但爆速变化不大,20kPa条件下猛度比常压条件下提高8.4%;随着环境压力的降低,复合板界面波高和波长逐渐增大,20kPa条件下波高比常压下增加了49%,波长增加了23%;负压条件下T2/Q235结合面氧元素含量低于常压环境;数值模拟结果表明,T2/Q235界面波随着炸药的装药密度变大而增大,与实验结果一致。在爆炸焊接时密度为0.8g/cm^(3)(20kPa)比0.711g/cm^(3)(常压)炸药碰撞速度提高了16.3%,碰撞压力提高了66.3%。研究表明,负压相比于常压条件提高了爆炸焊接的炸药能量利用率。

关键词：爆炸力学爆炸焊接微观界面粉状乳化炸药数值模拟

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(Ba,K)Fe_(2)As_(2)铁基超导多芯线材的晶间耦合强化与性能提高

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Science China Materials 2024年第1期67卷 301-310页

作者：郭文文姚超熊颢杨鹏涂畅马衍伟 Key Laboratory of Applied Superconductivity Institute of Electrical EngineeringChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Institute of Electrical Engineering and Advanced Electromagnetic Drive Technology Qilu ZhongkeJinan 250013China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China

铁基超导材料在高场超导磁体领域具有很大的应用潜力,而研究具有高传输临界电流密度的多芯复合包套线材对于其实际应用至关重要.本研究基于粉末装管法,结合孔型轧制工艺和热等静压烧结工艺制备了多芯Cu/Ag复合包套(Ba,K)Fe_(2)As_(2)(Ba... 详细信息

铁基超导材料在高场超导磁体领域具有很大的应用潜力,而研究具有高传输临界电流密度的多芯复合包套线材对于其实际应用至关重要.本研究基于粉末装管法,结合孔型轧制工艺和热等静压烧结工艺制备了多芯Cu/Ag复合包套(Ba,K)Fe_(2)As_(2)(Ba-122)超导线材.通过对不同直径线材中Ba-122超导芯的质量密度、晶粒取向、晶粒尺寸、元素分布与线材的电流传输性能之间的关系进行系统研究,我们发现线径较小的样品中超导晶粒间的耦合得到了显著增强,其传输临界电流密度在4.2 K,10 T下达到3.3×10^(4)A cm^(-2),同时由于晶粒尺寸和超导芯丝的均匀性得到改善,其电流传输的一致性(n值)也获得有效提高.本研究为制备高性能、高度均匀的铁基超导多芯线材提供了一种可规模化的工艺路线,对促进铁基超导材料的高场强电应用有重要意义.

关键词：热等静压烧结孔型轧制晶粒取向临界电流密度晶粒间质量密度晶粒尺寸工艺路线

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Synthesis and Crystal Structure of 4-(4-Bromophenyl)- 3,4-dihydro-6-methyl quinolin-2(1H)-one

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Chinese Journal of Structural Chemistry 2007年第5期26卷 533-536页

作者： YU Chen-Xia ZHU Xiao-Tong YAO chang-Sheng tu Shu-Jiang Department of Chemistry Xuzhou Normal University Xuzhou 221116 China Key Laboratory of Biotechnology for Medical Plants of Jiangsu Province Xuzhou 221116 China

The title compound （C16H14BrNO） has been synthesized by the reaction of p-tolylamine, Meldrum’s acid and 4-bromo-benzaldehyde, and its structure was characterized by IR, 1H NMR and X-ray single-crystal diffraction. The crystal belongs to monoclinic, space group P21/n with a = 7.6850（11）, b = 8.3004（11）, c = 21.301（3）A, β = 95.110（2）°, V = 1353.4（3） A^3, Mr = 316.19, Z = 4, Dc = 1.552 g/cm^3, μ（MoKα） = 3.028 mm-1, F（000） = 640, the final R = 0.0345 and wR = 0.0768. X-ray analysis reveals that the atoms of C（1）, C（2）, C（3）, C（4）, C（5） and N（1） form a six-membered ring of boat conformation.

关键词： quinoline crystal structure

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Significance of serum fibroblast growth factor-23 and miR-208b in pathogenesis of atrial fibrillation and their relationship with prognosis

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World Journal of Clinical Cases 2020年第16期8卷 3458-3464页

作者： Jie-Min Chen Yao-Tang Zhong chang tu Jun Lan Department of Cardiovascular Medicine Dongguan Songshan Lake Central HospitalDongguan Institute of Cardiovascular DiseaseDongguan 523326Guangdong ProvinceChina

BACKGROUND The incidence and prevalence of atrial fibrillation are increasing each year,and this condition is one of the most common clinical *** To investigate the levels and significance of serum fibroblast growth factor 23(FGF-23)and miR-208 b in patients with atrial fibrillation and their relationship with *** From May 2018 to October 2019,240 patients with atrial fibrillation were selected as an observation group,including 134 with paroxysmal atrial fibrillation and 106 with persistent atrial fibrillation;150 patients with healthy sinus rhythm were selected as a control *** serum levels of FGF-23 and miR-208 b in the two groups were *** the observation group,cardiac parameters were determined by *** The serum levels of FGF-23 and miR-208 b in the observation group were 210.20±89.60 ng/mL and 5.30±1.22 ng/mL,which were significantly higher than the corresponding values in the control group(P0.05).The serum levels of FGF-23and miR-208 b were positively correlated with the LAD(r=0.411 and 0.382,P<0.05).In the observation group,the serum levels of FGF-23 and miR-208 b in patients with a major cardiovascular event(MACE)were 243.30±72.29 ng/mL and 6.12±1.12 ng/mL,which were significantly higher than the corresponding values in patients without a MACE(P<0.05).CONCLUSION The serum levels of FGF-23 and miR-208 b are increased in patients with atrial fibrillation and are related to the type of disease,cardiac parameters,and prognosis.

关键词： Fibroblast growth factor-23 MiR-208b Atrial fibrillation Prognosis

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Identification of an immune-related signature for the prognosis of uveal melanoma

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International Journal of Ophthalmology(English edition) 2020年第3期13卷 458-465页

作者： Ying-Zi Li Ying Huang Xiang-Yang Deng chang-Sen tu Eye Hospital Wenzhou Medical UniversityWenzhou 32500Zhejiang ProvinceChina Department of Neurosurgery the Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina

AIM:To construct an immune-related prognostic signature(IPS)that can distinguish and predict prognosis in uveal melanoma(UM).METHODS:The transcriptomic data and clinicopathological information of 80 UM patients were extracted from the TCGA *** patients were randomly assigned to a training and a testing ***:Lasso Cox analysis was performed for the prognostic immune-related genes to develop an IPS for UM in the training *** signature was validated in both the testing set and entire *** confirmed the prognostic value of our IPS in distinct subgroups and found its association with the T stage and basal diameter of the *** Immune Estimation Resource database analysis revealed that the IPS was negatively correlated with the infiltration of neutrophils and dendritic cells,but positively correlated with the infiltration level of CD8+T *** addition,we demonstrated that immune checkpoints containing PD-1,CTLA-4,IDO,and TIGIT were moderately associated with the ***:This is the first study to develop and validate an immune-related signature with the ability of predicting prognosis for UM *** studies are needed to validate its prediction accuracy.

关键词： uveal melanoma TCGA prognosis immune-related signature

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ReLoc:Indoor Visual Localization with Hierarchical Sitemap and View Synthesis

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Journal of Computer Science & Technology 2021年第3期36卷 494-507页

作者： Hui-Xuan Wang Jing-Liang Peng Shi-Yi Lu Xin Cao Xue-Ying Qin chang-He tu School of Computer Science and Technology Shandong UniversityQingdao 266237China School of Information Science and Engineering University of JinanJinan 250022China School of Software Shandong UniversityJinan 250101China

Indoor visual localization,i.e.,6 Degree-of-Freedom camera pose estimation for a query image with respect to a known scene,is gaining increased attention driven by rapid progress of applications such as robotics and augmented ***,drastic visual discrepancies between an onsite query image and prerecorded indoor images cast a significant challenge for visual *** this paper,based on the key observation of the constant existence of planar surfaces such as floors or walls in indoor scenes,we propose a novel system incorporating geometric information to address issues using only pixelated *** the system implementation,we contribute a hierarchical structure consisting of pre-scanned images and point cloud,as well as a distilled representation of the planar-element layout extracted from the original dataset.A view synthesis procedure is designed to generate synthetic images as complementary to that of a sparsely sampled ***,a global image descriptor based on the image statistic modality,called block mean,variance,and color(BMVC),was employed to speed up the candidate pose identification incorporated with a traditional convolutional neural network(CNN)*** results on a popular benchmark demonstrate that the proposed method outperforms the state-of-the-art approaches in terms of visual localization validity and accuracy.

关键词： visual localization planar surface statistic information view synthesis

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2.1亚型猪瘟病毒流行株E2蛋白单克隆抗体的制备及其抗原表位的鉴定

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中国预防兽医学报 2024年第5期46卷 511-521页

作者：张艺潇吴梦米士江刘钟迪涂长春龚文杰吉林大学动物医学学院吉林长春130062 中国农业科学院长春兽医研究所吉林长春130012 重庆市畜牧科学院重庆408599

为获得仅与我国基因2.1亚型猪瘟病毒(CSFV)流行株反应的单克隆抗体(MAb),并揭示疫苗株与流行株E2蛋白抗原氨基酸的差异,本研究利用基因2.1亚型重组质粒p FastBac1-JL23 E2通过杆状病毒表达重组E2蛋白(rE2),并采用Ni柱纯化后经SDS-PAGE检... 详细信息

为获得仅与我国基因2.1亚型猪瘟病毒(CSFV)流行株反应的单克隆抗体(MAb),并揭示疫苗株与流行株E2蛋白抗原氨基酸的差异,本研究利用基因2.1亚型重组质粒p FastBac1-JL23 E2通过杆状病毒表达重组E2蛋白(rE2),并采用Ni柱纯化后经SDS-PAGE检测r E2的表达及纯化效果;采用western blot鉴定r E2的反应原性。SDS-PAGE及western blot结果表明经杆状病毒表达了基因2.1亚型CSFV E2蛋白,且其纯化效果和反应原性均较好。采用杂交瘤技术制备2.1基因亚型CSFV E2蛋白的单克隆抗体(MAb),采用亲和层析法纯化该MAb,采用BCA法测定其浓度及亚类。将79株1.1、2.1、2.2和2.3基因亚型的CSFV及1.1基因亚型的HCLV株和SM株感染PK-15细胞,72 h后采用IFA检测MAb与不同基因型CSFV的反应性;采用western blot鉴定MAb与10个基因亚型共18种CSFV代表株E2蛋白的反应性。采用IFA鉴定MAb与不同基因型CSFV的中和活性。结果显示,经IFA筛选后共获得16株分泌E2蛋白MAb的杂交瘤细胞株。其中仅一株MAb TCH061与所有2.1基因亚型(2.1a、2.1b、2.1c、2.1g、2.1h、2.1i、2.1j、2.1k、2.1l、2.1m、2.1n)CSFV感染的细胞反应后出现绿色荧光,与基因1.1亚型HCLV疫苗株和SM株以及其他基因型CSFV感染的细胞反应后均无绿色荧光;western blot结果显示,该MAb能够识别2.1基因亚型CSFV E2蛋白(2.1a、2.1b、2.1c、2.1g、2.1h、2.1i、2.1j),在90 ku处出现特异性条带,而与其他基因型CSFV E2蛋白均不反应。表明TCH061为2.1基因亚型CSFV E2蛋白特异性的MAb。MAb的纯化结果显示,在50 ku和25 ku处有明显条带,其浓度为1.70μg/μL且该MAb TCH061重链为Ig G2a,轻链为κ链。中和活性结果显示,TCH061对JL^(23)株(2.1b)、GDLF1株(2.1c)有一定的中和活性,但不能中和C株。分别以GD53株E^(24)个不同区域的截短蛋白为抗原通过western blot初步确定MAb识别抗原表位的区域。利用CLC Sequence Viewer比对与MAb反应的CSFV E2蛋白氨基酸序列的差异,通过SWISS-MODEL预测MAb抗原表位的关键氨基酸位点。利用杆状病毒表达CSFV JL^(23)株各位点突变后的E2蛋白,采用western blot鉴定各突变的E2蛋白与MAb TCH061的反应性。Western blot结果显示,TCH061的抗原表位位于E2蛋白的aa1~aa90,且其识别CSFV E2蛋白P^(20)不识别L^(20)的CSFV。通过SWISS-MODEL预测E2蛋白氨基酸序列的I18、G^(19)、P^(20)、L^(21)、G^(22)、A^(23)和E^(24)在空间上比较接近;MAb TCH061与JL^(23)株I18M突变的E2蛋白反应,与G^(19)K、P^(20)L和L^(21)P突变的E2蛋白均不反应,与G^(22)K突变的E2蛋白反应性较弱,与HCLV E2蛋白不反应,但与HCLV L^(20)P突变的E2蛋白反应。证实TCH061的抗原表位为^(19)GPLG^(22),经Py MOL结构模拟确定其为空间构象表位;且除了aa^(20),其他位点在各基因型CSFV中均非常保守,表明P^(20)是2.1基因亚型CSFV流行株E2蛋白抗原表位的关键氨基酸。综上所述,本研究首次获得一株区别于CSFV疫苗株和2.1基因亚型CSFV流行株的MAb TCH061,揭示了疫苗株与流行株E2蛋白氨基酸位点的差异,为研发猪瘟疫苗和CSFV流行株感染的血清学鉴别检测方法的建立提供了重要的MAb资源。

关键词：猪瘟病毒单克隆抗体病毒反应性抗原表位

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Flexible Bis(benzimidazole)-based Ligands Directed the Structure Characteristics of Coordination Polymers Based on Diphenic Acid Co-ligands:Syntheses, Structures and Properties

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Chinese Journal of Structural Chemistry 2019年第1期38卷 155-164,5页

作者： tu chang-Zheng YANG Yu-Ting XU Li-Li YAN Bang-Ling WANG Fan College of Chemistry and Environmental Science Qujing Normal University

Two new coordination polymers [Cu_2(bbim)(dpa)_2(C_2H_5OH)_2](1), [Co(dpa)_2(bbbm)](2)(H_2dpa = diphenic acid, bbim = 1,1?-(1,6-hexanediyl)bis-1H-benzimidazole, bbbm = 1,1?-(1,4-butanediyl)bis-1 H-benzimidazole) constructed from bis(benzimidazole)-based ligands with different lengths and diphenic acid co-ligand have been synthesized under solvothermal *** 1 possesses Cu-dpa helical chains. The adjacent chains are connected by the bbim ligands into two-dimensional(2D) 3-connected(63) topology. Differently, the layer structure of 2 was consisted by one-dimensional chains containing alternated 8-and 18-membered rings. Furthermore,the thermal stability and fluorescence property for all crystalline materials have been investigated.

关键词： coordination polymer crystal structure diphenic acid bis(benzimidazole)-based ligands fluorescence

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