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Rare Metals 2014年第1期33卷 41-46页

作者： Yan xin Liang chai School of Energy Power and Mechanical Engineering North China Electric Power University Beijing Key Laboratory for Advanced Functional Materials and Thin Film Technology

Microstructure, martensitic transformation behavior, mechanical and shape memory properties of ***25FexGa19 （x = 0, 2, 4, 6, 8） shape memory alloys were investigated using optical microscopy （OM）, X-ray diffraction analysis （XRD）, differential scanning calorimeter （DSC）, and compressive test. It is found that these alloys are composed of single non-modulated martensite phase with tetragonal structure at room temperature, which means substituting Fe for Ni in Ni56Mn25Ga19 alloy has no effect on phase structure. These alloys all exhibit a ther- moelastic martensitic transformation between the cubic parent phase and the tetragonal martensite phase. With the increase of Fe content, the martensitic transformation peak temperature （Mp） decreases from 356℃ for x = 0 to 20℃ for x = 8, which is contributed to the depressed electron concentration and tetragonality of martensite. Fe addition remarkably reduces the transformation hysteresis of Ni-Mn-Ga alloys. Substituting Fe for Ni in Ni56Mn25Ga19 alloy can decrease the strength of the alloys and almost has no influence on the ductility and shape memory property.

关键词： Shape memory alloys Microstructure Martensitic transformation Ni-Mn-Fe-Ga

New Family of 3-DOF UP-Equivalent Parallel Mechanisms with High Rotational Capability

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Chinese Journal of Mechanical Engineering 2018年第1期31卷 66-77页

作者： Wei Ye Qin-Chuan Li xin-Xue chai Faculty of Mechanical Engineering and Automation Zhejiang Sci-Tech University

Parallel mechanisms(PMs) having the same motion characteristic with a UP kinematic chain(U denotes a universal joint, and P denotes a prismatic joint) are called UP-equivalent PMs. They can be used in many applications, such as machining and milling. However, the existing UP-equivalent PMs suffer from the disadvantages of strict assembly requirements and limited rotational capability. Type synthesis of UP-equivalent PMs with high rotational capability is *** special 2 R1 T motion is briefly discussed and the fact that the parallel module of the Exechon robot is not a UP-equivalent PM is disclosed. Using the Lie group theory, the kinematic bonds of limb chains and their mechanical generators are presented. Structural conditions for constructing such UP-equivalent PMs are proposed,which results in numerous new architectures of UP-equivalent PMs. The high rotational capability of the synthesized mechanisms is illustrated by an example. The advantages of no strict assembly requirements and high rotational capability of the newly developed PMs will facilitate their applications in the manufacturing industry.

关键词： Parallel mechanism Group theory Type synthesis High rotational capability

Agricultural Load Modeling Based on Crop Evapotranspiration and Light Integration for Economic Operation of Greenhouse Power Systems

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CSEE Journal of Power and Energy Systems 2021年第5期7卷 1113-1121页

作者： Zeming Li Junyong Liu Yue Xiang xin Zhang Yanxin chai College of Electrical Engineering Sichuan UniversityChengdu 610065China. Energy and Power Theme School of WaterEnergy and EnvironmentCranfield UniversityCranfield MK430ALUK.

The threat of environmental degradation attracts great attention to clean energy production and ***,the limited scope of energy consumption causes the large-scale of clean energy sources to be abandoned in Sichuan *** the meantime,the development of modern greenhouse cultivation has transformed the agriculture industry to develop a brand-new type of electrical load in the ***,the agricultural load can be used to consume the clean energy while facilitating plant *** this paper,an innovative agricultural load model is proposed based on crop evapotranspiration and daily light ***,the proposed agricultural load model is also applied to investigate the electricity consumption of five types of crop *** results illustrate that the power consumption is primarily driven by an artificial lighting compensation system.

关键词： Agriculture load model crop evapotranspiration model daily light integration model power consumption

Microstructure and Mechanical Properties of C/C-ZrC-SiC Composites Fabricated by Reactive Melt Infiltration with Zr,Si Mixed Powders

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Journal of Materials Science & Technology 2013年第8期29卷 702-710页

作者： xin Yang Zhean Su Qizhong Huang Xiao Fang Liyuan chai School of Metallurgical Science and Engineering Central South University State Key Laboratory of Powder Metallurgy Central South University

To meet the increasing demand for advanced materials capable of operation over 2000 ℃ for future thermal protection systems application, C/C-ZrC-SiC composites were fabricated by reactive melt infiltration （RMI） with Zr, Si mixed powders as raw materials. The structural evolution and formation mechanism of the C/C- ZrC-SiC composites were discussed, and the mechanical property of the as-prepared material was investigated by compression test. The results showed that after the RMI process, a special structure with ZrC-SiC multi-coating as outer layer and ZrC-SiC-PyC ceramics as inner matrix was formed. ZrC and SiC rich areas were formed in the composites and on the coating surface due to the formation of Zr-Si intermetallic compounds in the RMI process. Mechanical tests showed that the average compression strength of the C/C-ZrC-SiC composites was 133.86 MPa, and the carbon fibers in the composites were not seriously damaged after the RMI process.

关键词： Carbon/carbon composites Reactive melt infiltration Coating ZrC SiC

Shape-Controlled Synthesis of Octahedral α-NaYF_(4) and Its Rare Earth Doped Submicrometer Particles in Acetic Acid

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Nano Research 2009年第7期2卷 565-574页

作者： Li Gao xin Ge Zhanli chai Guohai Xu xin Wang Cheng Wang State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChangchun 130022China Graduate School of the Chinese Academy of Sciences Beijing 100049China Division of Chemical and Biomolecular Engineering Nanyang Technological UniversitySingapore 637459

Submicrometer sized pure cubic phase,Eu^(3+)doped,and Yb^(3+)/Er^(3+)co-dopedα-NaYF4 particles with octahedral morphology have been prepared in acetic *** acetate anion plays a critical role in the formation of such symmetric octahedral structures through its selective adsorption on the(111)faces of the *** size of the as-prepared octahedra can be tuned by varying the amount of sodium acetate added to the acetic acid.A possible formation mechanism for these octahedra has been *** dopedα-NaYF_(4) octahedral submicrometer particles show down-conversion and up-conversion photoluminescence typical of these materials.

关键词： α-NaYF_(4) octahedral acetic acid photoluminescence

Targeting the PD-L1 cytoplasmic domain and its regulatory pathways to enhance cancer immunotherapy

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Journal of Molecular Cell Biology 2023年第11期15卷 12-20页

作者： Fangni chai Pan Li xin Liu Zhihui Zhou Haiyan Ren Division of Respiratory and Critical Care Medicine West China Hospital of Sichuan UniversityChengdu 610041China Collaborative Innovation Center of Biotherapy Chengdu 610041China

As a significant member of the immune checkpoint,programmed cell death 1 ligand 1(PD-L1)plays a critical role in cancer immune escape and has become an important target for cancer *** approved drugs mainly target the extracellular domain of ***,the small cytoplasmic domain of PD-L1 has been reported to regulate PD-L1 stability and function through multiple ***,the intracellular domain of PD-L1 and its regulatory pathways could be promising targets for cancer therapy,expanding available strategies for combined ***,we summarize the emerging roles of the PD-L1 cytoplasmic domain and its regulatory *** conserved motifs,homodimerization,and posttranslational modifications ofthe PD-L1 cytoplasmic domain have been reported to regulate the membrane anchoring,degradation,nucleartranslocation,and glycosylation of *** summary provides a comprehensive understanding of the functions of the PD-L1 cytoplasmic domain and evaluates the broad prospects for targeted therapy.

关键词： PD-L1 cytoplasmic domain immunotherapy posttranslational modification

Molecular characterization and functional analysis of a piscidin gene in large yellow croaker (Larimichthys crocea)

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Zoological Research 2016年第6期37卷 347-355页

作者： Jing YANG xin-Jiang LU Fang-Chao chai Jiong CHEN Laboratory of Biochemistry and Molecular Biology School of Marine SciencesNingbo University Collaborative Innovation Center for Zhejiang Marine High-Efficiency and Healthy Aquaculture Ningbo University

The piscidin family, which includes potent antimicrobial peptides with broad-spectrum activity, plays an important role in the innate immune system of fish. In this study, we cloned piscidin-5-1ike type 3 （Lcpis51t3） in large yellow croaker （Larimichthys crocea）. Multiple alignments with other known piscidins revealed amino acid conservation throughout the fish, especially at the signal peptide （22 amino acids）. The phylogenetic tree confirmed that Lcpis51t3 and large yellow croaker piscidin-5-1ike proteins were grouped together to form a branch. Quantitative real-time PCR revealed that Lcpis51t3 was expressed in a wide range of tissues, including the brain, muscle, gill, head kidney, intestine, kidney, liver, and spleen. The highest mRNA expression level of Lcpis51t3 was found in the spleen. After Vibrio alginolyticus infection, mRNA expression was rapidly upregulated in the liver, head kidney, gill, kidney, and intestine at 4, 8, 12, and 24 h post infection （hpi）, whereas there were no significant changes in the spleen. The antimicrobial spectrum showed that the synthetic mature peptide of Lcpis51t3 exhibited different activity in vitro against various bacteria, such as Aeromonas hydrophila, V. anguillarum, V. alginolyticus, V. parahaemolyticus, Staphylococcus aureus, and Listeria monocytogenes In addition, survival rates from the in vivo assay indicated that the synthetic peptide of Lcpis51t3 increased the survival rate of large yellow croaker after V. alginolyticus challenge, resulting in a decline in bacterial burden and mRNA expression levels of interleukin-ll3, interleukin-10, and tumor necrosis factor-（]. These data suggest that Lcpis51t3 plays an important role in innate immunity in large yellow croaker and might represent a potential therapeutic agent against pathogen invasion.

关键词： Antimicrobial activity Large yellowcroaker Piscidin Survival rate Vibrio alginolyticus

Glucose oxidase as a blocking agent-based signal amplification strategy for the fabrication of label-free amperometric immunosensors

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Science China Chemistry 2011年第3期54卷 536-544页

作者： SONG ZhongJu YUAN Ruo chai YaQin CHE xin LV Ping Key Laboratory on Luminescence and Real-Time Analysis Ministry of EducationCollege of Chemistry and Chemical EngineeringKey Laboratory of Eco-environments in Three Gorges Reservoir RegionSouthwest UniversityChongqing 400715China

An effective electrochemical signal amplification strategy based on enzyme membrane modification and redox probe immobilization was proposed to construct an amperometric immunosensor.L-cysteine@ferrocene functionalized chitosan,which possessed not only efficient redox-activity but also excellent film-forming ability,was coated on the bare glass carbon electrode. Moreover,the thiol groups(SH)in the ferrocenyl compound were used for gold nanoparticles immobilization via the strong bonding interaction,which could further be utilized for the immobilization of antibody biomolecules with well-retained ***,glucose oxidase(GOD)as the enzyme membrane was employed to block the possible remaining active sites and avoid the nonspecific *** the excellent electrocatalytic properties of GOD towards glucose,the amplification of antigen-antibody interaction and the enhanced sensitivity could be *** the optimal conditions,the linear range of the proposed immunosensor for the determination of carcinoembryonic antigen(CEA)was from 0.05 to 100 ng/mL with a detection limit of 0.02 ng/mL(S/N=3).Moreover,the immunosensor exhibited good selectivity,stability and reproducibility, which provided a promising potential for clinical immunoassay.

关键词： amperometric immunosensor chitosan gold colloidal nanoparticles(GNPs) Ferrocene-monocarboxylic(Fc-COOH) carcinoembryonic antigen(CEA)

Visual learning graph convolution for multi-grained orange quality grading

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Journal of Integrative Agriculture 2023年第1期22卷 279-291页

作者： GUAN Zhi-bin ZHANG Yan-qi chai Xiu-juan chai xin ZHANG Ning ZHANG Jian-hua SUN Tan Agricultural Information Institute Chinese Academy of Agricultural SciencesBeijing 100081P.R.China Key Laboratory of Agricultural Big Data Ministry of Agriculture and Rural AffairsBeijing 100081P.R.China National Nanfan Research Institute(Sanya) Chinese Academy of Agricultural SciencesSanya 572024P.R.China

The quality of oranges is grounded on their appearance and *** refers to the skin’s smoothness and surface cleanliness;diameter refers to the transverse diameter *** are visual attributes that visual perception technologies can automatically ***,the current orange quality assessment needs to address two issues:1)There are no image datasets for orange quality grading;2)It is challenging to effectively learn the fine-grained and distinct visual semantics of oranges from diverse *** study collected 12522 images from 2087 oranges for multi-grained grading *** addition,it presented a visual learning graph convolution approach for multi-grained orange quality grading,including a backbone network and a graph convolutional network(GCN).The backbone network’s object detection,data augmentation,and feature extraction can remove extraneous visual *** was utilized to learn the topological semantics of orange feature ***,evaluation results proved that the recognition accuracy of diameter size,appearance,and fine-grained orange quality were 99.50,97.27,and 97.99%,respectively,indicating that the proposed approach is superior to others.

关键词： GCN multi-view fine-grained visual feature appearance diameter size