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Journal of Systems Science & Complexity 2022年第6期35卷 2302-2318页

作者： YANG Ying chai rui SUN Xinyu LI Yiming School of Economics and Management Xidian UniversityXi'an 710126China Research Center for Digital Economy(Greater Bay Area) School of Economics and Management Shenzhen Research InstituteTsinghua UniversityShenzhen 518057China Meituan BC BlockWangjing Hengdian BuildingBeijing 100102China School of Management Xi'an Jiaotong UniversityXi'an 710049China

Motivated by the practice that e-sellers cooperate with insurance companies to offer consumers the return-freight insurance(RI),this paper aims to investigate the competing e-sellers’RI *** the information asymmetry in the online context,reputation system is widely applied by *** an online market with two competing e-sellers that sell the same product but are differentiated in their reputation,this paper builds an analytical model to explore the e-sellers optimal pricing and RI *** with sellers’reputation and their RI strategies,the equilibrium outcomes under four cases are *** paper reveals the conditions that e-sellers are willing to offer ***,the findings demonstrate that low reputation e-seller is more likely to offer ***,when the sellers are more divergent,they are more likely to co-exist in the *** premium and RI compensation play critical roles in their *** introduction tends to increase the price,thus offsets the benefits of RI,but does not affect the total consumer surplus.

关键词： Game theory product returns reputation return-freight insurance

Quercetin protects against diabetic retinopathy in rats by inducing heme oxygenase-1 expression

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Neural Regeneration Research 2021年第7期16卷 1344-1350页

作者： Guang-rui chai Shu Liu Hong-Wei Yang Xiao-Long Chen Department of Ophthalmology Shengjing Hospital of China Medical UniversityShenyangLiaoning ProvinceChina Department of Geratology The First Affiliated Hospital of China Medical UniversityShenyangLiaoning ProvinceChina

Quercetin is a widely-occurring flavonoid that protects against cancer, and improves memory and cardiovascular ***, whether quercetin exhibits therapeutic effects in diabetic retinopathy remains *** this study, we established a rat model of streptozocininduced diabetic ***-two hours later, the rats were intraperitoneally administered 150 mg/kg quercetin for 16 successive *** markedly increased the thickness of the retinal cell layer, increased the number of ganglion cells, and decreased the overexpression of the pro-inflammatory factors interleukin-1β, interleukin-18, interleukin-6 and tumor necrosis factor-α in the retinal tissue as well as the overexpression of high mobility group box-1 and the overactivation of the NLRP3 ***, quercetin inhibited the overexpression of TLR4 and NF-κBp65, reduced the expression of the pro-angiogenic vascular endothelial growth factor and soluble intercellular adhesion molecule-1, and upregulated the neurotrophins brain-derived neurotrophic factor and nerve growth *** injection of the heme oxygenase-1 inhibitor zinc protoporphyrin blocked the protective effect of *** findings suggest that quercetin exerts therapeutic effects in diabetic retinopathy possibly by inducing heme oxygenase-1 *** study was approved by the Animal Ethics Committee of China Medical University, China(approval No.2016 PS229K) on April 8, 2016.

关键词： angiogenesis diabetic retinopathy flavonoid heme oxygenase-1 inflammation neurotrophin quercetin repair

Clinical features,radiological imaging,and treatment strategies of nonmetallic intraorbital foreign bodies:a retrospective analysis

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International Journal of Ophthalmology(English edition) 2023年第7期16卷 1130-1137页

作者： Guang-rui chai Ming Chen Zi-Xun Song Lu Liu Department of Ophthalmology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

AIM:To provide comprehensive data on nonmetallic intraorbital foreign bodies(IOFBs)by summarizing and analyzing material types,clinical manifestations,imaging features,and treatment ***:Totally 28 nonmetallic IOFB cases treated at Shengjing Hospital of China Medical University from 2012 to 2020 were retrospectively *** types of foreign bodies,clinical features,imaging manifestations,and treatment outcomes were ***:Among all cases,67.8%(19/28)of the foreign bodies were *** top three entrances were the upper eyelid skin(7/28),lower fornix conjunctiva(6/28),and lower eyelid skin(4/28).In most cases(11/28,39.3%),foreign bodies remained in the medial *** major clinical manifestations included eyelid redness and swelling(20/28,71.4%),conjunctival congestion and edema(17/28,60.7%),and ophthalmoptosis(15/28,53.6%).Infection was the main complication,which occurred in 57.1%(16/28)of all *** tomography(CT)values differed for different foreign bodies and varied in the different periods after *** plant-and grease-derived foreign bodies and the surrounding pus cysts showed different signals on magnetic resonance imaging(MRI).The prognosis varied with different foreign body types,surgery timing,and intraoperative ***:The majority of nonmetallic IOFBs are organic and often remain in the superior,medial,and inferior areas of the *** manifestations vary owing to their different *** and MRI facilitate the identification of foreign body ***-derived foreign bodies should be completely removed,and surgical treatment is a complicated process.

关键词： orbital trauma nonmetallic intraorbital foreign body clinical manifestations computed tomography magnetic resonance imaging

Comparison of the femtosecond Laser and mechanical microkeratome for flap cutting in LASIK

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International Journal of Ophthalmology(English edition) 2015年第4期8卷 784-790页

作者： Li-Kun Xia Jie Yu Guang-rui chai Dang Wang Yang Li Department of Ophthalmology Shengjing Hospital of China Medical University

· AIM: To compare refractive results, higher-order aberrations(HOAs), contrast sensitivity and dry eye after laser in situ keratomileusis(LASIK) performed with a femtosecond laser versus a mechanical microkeratome for myopia and astigmatism.·METHODS: In this prospective, non-randomized study,120 eyes with myopia received a LASIK surgery with the Visu Max femtosecond laser for flap cutting, and 120 eyes received a conventional LASIK surgery with a mechanical microkeratome. Flap thickness, visual acuity, manifest refraction, contrast sensitivity function(CSF) curves,HOAs and dry-eye were measured at 1wk; 1, 3, 6mo after surgery.·RESULTS: At 6mo postoperatively, the mean central flap thickness in femtosecond laser procedure was113.05 ±5.89 μm(attempted thickness 110 μm), and148.36 ±21.24 μm(attempted thickness 140 μm) in mechanical microkeratome procedure. An uncorrected distance visual acuity(UDVA) of 4.9 or better was obtained in more than 98% of eyes treated by both methods, a gain in log MAR lines of corrected distance visual acuity(CDVA) occurred in more than 70% of eyes treated by both methods, and no eye lost ≥1 lines of CDVA in both groups. The difference of the mean UDVA and CDVA between two groups at any time post-surgery were not statistically significant(P >0.05). The postoperative changes of spherical equivalent occurred markedly during the first month in both groups. The total root mean square values of HOAs and spherical aberrations in the femtosecond treated eyes were markedly less than those in the microkeratome treated eyes during 6mo visit after surgery(P <0.01). The CSF values of the femtosecond treated eyes were also higherthan those of the microkeratome treated eyes at all space frequency(P <0.01). The mean ocular surface disease index scores in both groups were increased at 1wk, and recovered to preoperative level at 1mo after surgery. The mean tear breakup time(TBUT) of the femtosecond treated eyes were markedly longer than those of the

关键词： laser in situ keratomileusis femtosecond laser flap visual acuity higher-order aberrations contrast sensitivity dry eye

Theoretic computing model of combustion process of asphalt smoke

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Journal of Central South University of Technology 2005年第z1期12卷 88-93页

作者： HUANG rui chai Li-yuan HE De-wen PENG Bing WANG Yun-yan College of Metallurgical Science and Engineering Central South University Changsha 410083 China College of Metallurgical Science and Engineering Central South University Changsha 410083 China College of Metallurgical Science and Engineering Central South University Changsha 410083 China College of Metallurgical Science and Engineering Central South University Changsha 410083 China College of Metallurgical Science and Engineering Central South University Changsha 410083 China

Based on the data and methods provided by research literature, dispersing mathematical model of combustion process of asphalt smoke is set by theoretic analysis. Through computer programming, the dynamic combustion process of asphalt smoke is calculated to simulate an experimental model. The computing result shows that the temperature and the concentration of asphalt smoke influence its burning temperature in approximatively linear manner. The consumed quantity of fuel to ignite the asphalt smoke needs to be measured from the two factors.

关键词： asphalt smoke combustion concentration mathematical model

Mechanism of Shengmai Injection on Anti-Sepsis and Protective Activities of Intestinal Mucosal Barrier in Mice

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Chinese Journal of Integrative Medicine 2022年第9期28卷 817-822页

作者： LU Juan YU Yue WANG Xiao-jing chai rui-ping LYU Xin-kai DENG Ming-hui HU Mei-geng QI Yun CHEN Xi Institute of Medicinal Plant Development Chinese Academy of Medical SciencesPeking Union Medical CollegeBeijing100193China

Objective:To study the mechanism of Shengmai Injection(SMI)on anti-sepsis and protective activities of intestinal mucosal ***:The contents of 11 active components of SMI including ginsenoside Rb1,Rb2,Rb3,Rd,Re,Rf,Rg1,Rg2,ophioposide D,schisandrol A and schisantherin A were determined using ultra-performance liquid *** mice were randomly divided into the blank,the model,the low-,medium-and high-dose SMI groups(0.375,0.75,1.5 mL/kg,respectively)by random number table,10 mice in each *** SMI group,SMI was administrated to mice daily via tail vein injection for 3 consecutive days,while the mice in the blank and model groups were given 0.1 mL of normal *** hour after the last SMI administration,except the blank group,the mice in other groups were intraperitoneally injected with lipopolysaccharide(LPS)saline solution(2 mL/kg)at a dosage of 5 mL/kg for development of endotoxemia mice *** mice in the blank group were given the same volume of normal *** factors including interferon-γ(INF-γ),tumor necrosis factor-α(TNF-α),interleukin(IL)-2 and IL-10 were measured by flow *** light-chain kinase(MLCK),nuclear factorκB(NF-κB)levels,and change of Occludin proteins in jejunum samples were analyzed by Western ***:The decreasing trends of INF-γ,TNF-α and IL-2 were found in serum of SMI treatment *** SMI-treated mice,the content of Occludin increased and MLCK protein decreased compared with the model group(P0.05).Conclusion:SMI may exert its anti-sepsis activity mainly through NF-κB-pro-inflammatory factor-MLCK-TJ cascade.

关键词： Shengmai Injection sepsis intestinal mucosal barrier mechanism Chinese medicine

Knockdown of polypyrimidine tract binding protein facilitates motor function recovery after spinal cord injury

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Neural Regeneration Research 2023年第2期18卷 396-403页

作者： Ri-Yun Yang rui chai Jing-Ying Pan Jing-Yin Bao Pan-Hui Xia Yan-Kai Wang Ying Chen Yi Li Jian Wu Gang Chen Department of Histology and Embryology Medical School of Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu Province and the Ministry of Education Co-innovation Center of NeuroregenerationNantong UniversityNantongJiangsu ProvinceChina Center for Basic Medical Research Medical School of Nantong UniversityNantongJiangsu ProvinceChina Department of Anesthesiology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

After spinal cord injury(SCI),a fibroblast-and microglia-mediated fibrotic scar is formed in the lesion core,and a glial scar is formed around the fibrotic scar as a res ult of the activation and proliferation of ***,a large number of neuro ns are lost in the injured *** the dense glial scar and re plenishing neurons in the injured area are essential for SCI *** tra ct binding protein(PTB),known as an RNA-binding protein,plays a key role in ***,we utilized short hairpin RNAs(shRNAs)and antisense oligonucleotides(ASOs)to knock down PTB *** found that reactive spinal astrocytes from mice were directly reprogrammed into motoneuron-like cells by PTB downregulation in *** a mouse model of compressioninduced SCI,adeno-associated viral shRNA-mediated PTB knockdown replenished motoneuron-like cells around the injured *** Mouse Scale scores and forced swim,inclined plate,cold allodynia,and hot plate tests showed that PTB knockdown promoted motor function recovery in mice but did not improve sensory perception after ***,ASO-mediated PTB knockdown improved motor function resto ration by not only replenishing motoneuron-like cells around the injured area but also by modestly reducing the density of the glial scar without disrupting its overall ***,these findings suggest that PTB knockdown may be a promising therapeutic strategy to promote motor function recovery during spinal cord repair.

关键词： antisense oligonucleotides astrocytes glial scar motoneuron-like cells motor function neurogenesis neuron-like cells polypyrimidine tract binding protein short hairpin RNAs spinal cord repair

Changing Lane Probability Estimating Model Based on Neural Network

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Changing Lane Probability Estimating Model Based on Neural N...

第26届中国控制与决策会议

作者： Jianqun Wang rui chai Qingyang Wu School of Mechanical Engineering Beijing Institute of Technology

ISBN: (纸本)9781479937097

Changing lane is one of the methods to reach the destination faster and also could bring more highway traffic accidents. This study through the traffic feature recognition, cluster analysis, similarity measurements and estimation, analyzed the vehicle operation parameter before changing lane, proposed a changing lane probability estimating model which combines the SOM（Self-Organization Map） and BP（Back Propagation） artificial neural network and had passed the test of the Vissim micro traffic simulation data. This model contributes to the dynastic analysis and evaluation for establishing the traffic safe system.

关键词： traffic safety changing lane probability estimating model neural network

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综采工作面周期来压步距受回采速率影响研究

煤田地质与勘探 2016年第4期44卷 119-124,131页

作者：柴蕊中煤科工集团西安研究院有限公司陕西西安710077

为实现不同采煤速率条件下综采工作面周期来压步距的预测,保证来压时工作面稳定,以陕北某煤矿14204工作面为工程背景,通过对工作面支架压力实时监测得出矿压显现规律,并分别采用对数函数和双曲函数对周期来压步距受推采速率的影响进行... 详细信息

为实现不同采煤速率条件下综采工作面周期来压步距的预测,保证来压时工作面稳定,以陕北某煤矿14204工作面为工程背景,通过对工作面支架压力实时监测得出矿压显现规律,并分别采用对数函数和双曲函数对周期来压步距受推采速率的影响进行回归分析。分析结果表明,14204工作面平均来压步距为13.3 m;经过对比分析,发现双曲函数能很好的拟合推采速率对周期来压步距的影响;随回采速率的提高周期来压步距有所增加,但是由于工作面两端及中间位置的顶板所处的边界条件、地质条件等不尽相同,所以周期来压步距增加的幅度有所差异。研究成果为陕北地区综采工作面矿压显现规律的预测及控制提供了有益的实践经验。

关键词：回采速率综采工作面周期来压回归分析

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平顶山八矿地热温标的选取及热储温度估算

煤田地质与勘探 2010年第1期38卷 58-61页

作者：柴蕊煤炭科学研究总院西安研究院陕西西安710054

在地热系统中,地热温标通常被用来评价地下热储温度,但是众多地热温标计算出的热储温度往往相差很大,需要进一步判断矿物-流体的平衡状态。以平顶山八矿地热系统为例,讨论了地球化学温标的应用条件;通过Na-K-Mg三角图及以WATCH程序建立... 详细信息

在地热系统中,地热温标通常被用来评价地下热储温度,但是众多地热温标计算出的热储温度往往相差很大,需要进一步判断矿物-流体的平衡状态。以平顶山八矿地热系统为例,讨论了地球化学温标的应用条件;通过Na-K-Mg三角图及以WATCH程序建立的多矿物平衡法在该矿的应用,证实玉髓地热温标最适合估算该矿区深部热水温度,该矿区深部热水温度约为50℃。

关键词：地热温标热储温度水-岩平衡平顶山八矿