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Hemin-functionalized polypyrrole/paper-derived biochar electrocatalysts:Enhanced sensor platforms for H2O2

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Progress in Natural Science:Materials International 2024年第2期34卷 280-289页

作者： Yuhang Jiang Tianshuang Bao Xiangchuan Zhao Qi Wang Yue cao Jun cao Xingxiang Ji Weimeng Si School of Materials Science and Engineering Shandong University of Technology State Key Laboratory of Biobased Material and Green Papermaking Qilu University of Technology (Shandong Academy of Sciences)

As a H2O2electrochemical biomimetic enzyme sensor,the stability,repeatability and sensitivity of hemin-based composites are closely connected with the loading of hemin on high-performance matrix.Herein,polypyrrole/paper-derived carbon（PPy/PC） nanocomposite was used for the construction of a hemin-based non-enzymatic sensor to detect H2O2.Where the poplar wood is used to obtain crude cellulose through a straightforward papermaking process.This crude cellulose is then subjected to pyrolysis to yield the desired paper-based carbon material.The hemin-decorated PPy/PC was demonstrated possessing remarkable electrocatalytic activity for H2O2reduction,and the possible mechanism of the reactions was discussed.The electrochemical sensor,utilizing the HPPy/PC composite,achieved a low detection limit of 30 nM,along with enhanced selectivity and stability under optimized conditions.The favorable results observed can primarily be attributed to the superior electrochemical performance of PPy/PC,as well as its unique 3D interconnected structure.This structure effectively impedes the self-dimerization of hemin,thereby ensuring the generation of active catalytic species.

关键词： Biochar H2O2 sensing Hemin Paper-based carbon materials Paper-making process

A Novel CCA-NMF Whitening Method for Practical Machine Learning Based Underwater Direction of Arrival Estimation

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Journal of Beijing Institute of Technology 2024年第2期33卷 163-174页

作者： Yun Wu Xinting Li Zhimin cao School of Physics and Electronic Engineering Northeast Petroleum UniversityDaqing 163318China

Underwater direction of arrival(DOA)estimation has always been a very challenging theoretical and practical problem.Due to the serious non-stationary,non-linear,and non-Gaussian characteristics,machine learning based DOA estimation methods trained on simulated Gaussian noised array data cannot be directly applied to actual underwater DOA estimation tasks.In order to deal with this problem,environmental data with no target echoes can be employed to analyze the non-Gaussian components.Then,the obtained information about non-Gaussian components can be used to whiten the array data.Based on these considerations,a novel practical sonar array whitening method was proposed.Specifically,based on a weak assumption that the non-Gaussian components in adjacent patches with and without target echoes are almost the same,canonical cor-relation analysis(CCA)and non-negative matrix factorization(NMF)techniques are employed for whitening the array data.With the whitened array data,machine learning based DOA estimation models trained on simulated Gaussian noised datasets can be used to perform underwater DOA estimation tasks.Experimental results illustrated that,using actual underwater datasets for testing with known machine learning based DOA estimation models,accurate and robust DOA estimation performance can be achieved by using the proposed whitening method in different underwater con-ditions.

关键词： direction of arrival(DOA) sonar array data underwater disturbance machine learn-ing canonical correlation analysis(CCA) non-negative matrix factorization(NMF)

Energy-Efficient Driving Strategy for High-Speed Trains with Considering the Checkpoints

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Chinese Journal of Electronics 2024年第3期33卷 847-858页

作者： Zixuan ZHANG Yuan cao Shuai SU State Key Laboratory of Rail Traffic Control and Safety Beijing Jiaotong University School of Electronic and Information Engineering Beijing Jiaotong University National Engineering Research Center of Rail Transportation Operation and Control System Beijing Jiaotong University Frontiers Science Center for Smart High-speed Railway System Beijing Jiaotong University

With rising energy prices and concerns about environmental issues,energy-efficient driving strategies(EEDS) for high-speed trains have received a substantial amount of attention.In particular,energy-saving schemes play a huge role in reducing the energy and operating costs of trains.This article studies the EEDS of high-speed trains at a given time.A well-posed model is formulated,in which the constraints of the checkpoints,in addition to the speed limits,vehicle dynamics,and discrete control throttle,are first considered.For a given control sequence,the Karush-Kuhn-Tucker(KKT) conditions are used to obtain the necessary conditions for an EEDS.According to several key equations of the necessary conditions,the checkpoint constraints are satisfied.Some case studies are conducted based on the data of the Beijing-Shanghai high-speed line to illustrate the effectiveness of the proposed approach.

关键词： Energy consumption Costs Simulation Mathematical models Energy efficiency Vehicle dynamics Optimization

Simulation of wave scattering over a floating platform in the ocean with acoupled CFD-IBM model

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Theoretical & Applied Mechanics Letters 2024年第3期14卷 157-161页

作者： Pengxuan Luo Jingxin Zhang Yongyong cao Shaohong Song School of Naval Architecture Ocean&Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China MOE Key Laboratory of Hydrodynamics Shanghai Jiao Tong UniversityShanghai 200240China Shanghai city Tou waterway construction Co. LTDShanghai 200092China

A numerical study of linear wave scattering over a floating platform has been simulated by an efficient numericalmodel in this letter.The non-hydrostatic model is used to simulate the free surface and the uneven bottom.For thesolid body modelling,the immersed boundary method(IBM)is implemented by introducing a virtual boundaryforce into the momentum equations to emulate the boundary conditions.This implementation enhances theability of the model to simulate interactions between waves and floating structures.A numerical case involvingwave interactions with a floating platform is studied to validate the numerical model.By simulating the wavepropagation,the numerical model captures the variation of the wave scattering very well,which verifies theperformance of the numerical model and the robust strategy of the IBM.

关键词： Non-hydrostatic model Immersed boundary method Wave structure interaction Floating platform

Effects of simulated gut pH environment on bacterial composition and pheromone production of Dendroctonus valens

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Insect Science 2024年第1期31卷 225-235页

作者： Qingjie cao Yu Zhao Tuuli-Marjaana Koski Huiping Li Jianghua Sun College of Forestry Hebei Agricultural UniversityBaodingHebei ProvinceChina State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of ZoologyChinese Academy of SciencesBeijingChina College of Life Science/Hebei Basic Science Center for Biotic Interactions Institute of Life Science and Green DevelopmentHebei UniversityBaodingHebei ProvinceChina

Bark beetles are an economically and ecologically important insect group,with aggregation behavior and thus host colonization success depends on pheromone-mediated communication.For some species,such as the major invasive forest pest in China,red turpentine beetle(Dendroctonus valens),gut microbiota participates in pheromone production by converting tree monoterpenes into pheromone products.However,how variation in gut microenvironment,such as pH,affects the gut microbial composition,and consequently pheromone production,is unknown.In this study,we fed wild caught D.valens with 3 different pH media(main host diet with natural pH of 4.7;a mildly acidic diet with pH 6 mimicking the beetle gut pH;and highly acidic diet with pH 4),and measured their effects on the gut pH,bacterial community and production of the main aggregation and anti-aggregation pheromone(verbenone).We further tested the verbenone production capacity of 2 gut bacterial isolates in different pH environments(pH 6 and 4).Compared to natural state or main host diet,feeding on less acidic diet(pH 6)diluted the acidity of the gut,whereas feeding on highly acidic diet(pH 4)enhanced it.Both changes in gut pH reduced the abundance of dominant bacterial genera,resulting in decreased verbenone production.Similarly,the highest pheromone conversion rate of the bacterial isolates was observed in pH mimicking the acidity in beetle gut.Taken together,these results indicate that changes in gut pH can affect gut microbiota composition and pheromone production,and may therefore have the potential to affect host colonization behavior.

关键词： Dendroctonus valens gut bacteria gut pH verbenone

New insights into mechanisms and interventions of locoregional therapies for hepatocellular carcinoma

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Chinese Journal of Cancer Research 2024年第2期36卷 167-194页

作者： Hanyuan Liu Chunmei Wang Ruiqiang Wang Hengsong cao Yongfang cao Tian Huang Zhengqing Lu Hua Xiao Mengcheng Hu Hanjin Wang Jun Zhao Department of General surgery Nanjing First HospitalNanjing Medical UniversityNanjing 210019China Department of Oncology Sir Run Run HospitalNanjing Medical UniversityNanjing 211166China School of Public Health China Medical UniversityShenyang 110122China Hepatobiliary/Liver Transplantation Center the First Affiliated Hospital of Nanjing Medical UniversityKey Laboratory of Living Donor TransplantationChinese Academy of Medical SciencesNanjing 210024China Department of Gastroenterology the Affiliated Jiangning Hospital of Nanjing Medical UniversityNanjing 211103China Department of Nuclear Medicine the Affiliated Changzhou Second People's Hospital of Nanjing Medical UniversityChangzhou 213001China

Hepatocellular carcinoma(HCC) is responsible for a significant number of cancer-related deaths worldwide and its incidence is increasing. Locoregional treatments, which are precision procedures guided by imaging to specifically target liver tumors, play a critical role in the management of a substantial portion of HCC cases. These therapies have become an essential element of the HCC treatment landscape, with transarterial chemoembolization(TACE)being the treatment of choice for patients with intermediate to advanced stages of the disease. Other locoregional therapies, like radiofrequency ablation, are highly effective for small, early-stage HCC. Nevertheless, the advent of targeted immunotherapy has challenged these established treatments. Tyrosine kinase inhibitors(TKIs) and immune checkpoint inhibitors(ICIs) have shown remarkable efficacy in clinical settings. However, their specific uses and the development of resistance in subsequent treatments have led clinicians to reevaluate the future direction of HCC therapy. This review concentrates on the distinct features of both systemic and novel locoregional therapies. We investigate their effects on the tumor microenvironment at the molecular level and discuss how targeted immunotherapy can be effectively integrated with locoregional therapies. We also examine research findings from retrospective studies and randomized controlled trials on various combined treatment regimens, assessing their validity to determine the future evolution of locoregional therapies within the framework of personalized, comprehensive treatment.

关键词： Locoregional therapies transarterial chemoembolization hepatocellular carcinoma immunotherapy tumor microenvironment

A comprehensive review on microchannel heat sinks for electronics cooling

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International Journal of Extreme Manufacturing 2024年第2期6卷 133-162页

作者： Zhi-Qiang Yu Mo-Tong Li Bing-Yang cao Key Laboratory for Thermal Science and Power Engineering of Ministry of Education Department of Engineering MechanicsTsinghua UniversityBeijing 100084People’s Republic of China

The heat generation of electronic devices is increasing dramatically,which causes a serious bottleneck in the thermal management of electronics,and overheating will result in performance deterioration and even device damage.With the development of micro-machining technologies,the microchannel heat sink(MCHS)has become one of the best ways to remove the considerable amount of heat generated by high-power electronics.It has the advantages of large specific surface area,small size,coolant saving and high heat transfer coefficient.This paper comprehensively takes an overview of the research progress in MCHSs and generalizes the hotspots and bottlenecks of this area.The heat transfer mechanisms and performances of different channel structures,coolants,channel materials and some other influencing factors are reviewed.Additionally,this paper classifies the heat transfer enhancement technology and reviews the related studies on both the single-phase and phase-change flow and heat transfer.The comprehensive review is expected to provide a theoretical reference and technical guidance for further research and application of MCHSs in the future.

关键词： microchannel heat sink thermal management of electronics microscale heat transfer heat transfer enhancement

MTCR-CR Routing Strategy for Connection-Oriented Routing over Satellite Networks

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China Communications 2024年第5期21卷 280-296页

作者： Li Changhao Sun Xue Yan Lei cao Suzhi The University of Chinese Academy of Sciences Beijing 100094China Key Laboratory of Space Utilization Chinese Academy of SciencesBeijing 100094China Technology and Engineering Center for Space Utilization Chinese Academy of SciencesBeijing 100094China

The high-speed movement of satellites makes it not feasible to directly apply the mature routing scheme on the ground to the satellite network.DT-DVTR in the snapshot-based connectionoriented routing strategy is one of the representative solutions,but it still has room for improvement in terms of routing stability.In this paper,we propose an improved scheme for connection-oriented routing strategy named the Minimal Topology Change Routing based on Collaborative Rules(MTCR-CR).The MTCR-CR uses continuous time static topology snapshots based on satellite status to search for intersatellite link(ISL)construction solutions that meet the minimum number of topology changes to avoid route oscillations.The simulation results in Beidou-3 show that compared with DT-DVTR,MTCR-CR reduces the number of routing changes by about 92%,the number of path changes caused by routing changes is about38%,and the rerouting time is reduced by approximately 47%.At the same time,in order to show our algorithm more comprehensively,the same experimental index test was also carried out on the Globalstar satellite constellation.

关键词： ISL routing stability satellite networks satellite routing dynamic strategy

Impact pressure of waves generated by landslides on bank slopes

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Journal of Mountain Science 2024年第3期21卷 918-931页

作者： cao Ting WANG Pingyi QIU Zhenfeng LIU Jie Key Laboratory of Hydraulic and Waterway Engineering of Ministry of Education Chongqing Jiaotong UniversityChongqing 400074China Engineering Research Center of Diagnosis Technology and Instruments of Hydro-Construction Chongqing Jiaotong UniversityChongqing 400074China

Impulse waves that are generated by landslides in narrow reservoir areas threaten the stability of buildings and bank slopes.To discuss the action process and evolution law of the wave pressure on bank slopes,a three-dimensional physical model test that considers impulse waves generated by landslides was performed,and factors including landslide width,thickness,slope angles of the sliding surface,and bank slope angle were considered.Based on wave forms on the bank slopes,wave pressure curve characteristics,and peak value,the action process of wave pressure could be divided into the following stages:maximum pulsating pressure stage,wave impact stage(when waves break),and stationary pulsation stage.It was found that wave breaking is dependent on the value of the surf similarity parameterξ.The distribution pattern of impact pressure decays linearly on both sides of the maximum impact pressure point,and the attenuation degree decreases when it attains 40%of the maximum value.Thus,it is proposed that the prediction formula for the maximum effective impact pressure of the bank slope be related to the reciprocal of wave steepness,relative water depth,and slope rate.The prediction formula provides strong theoretical support for early safety warning and for predicting the bank slope under impulse waves generated by landslides.

关键词： Model test Impact pressure Action stage Breaking discrimination Distribution model