检索结果-南通市图书馆

维普期刊数据库博看期刊

表观气速对除磷污泥颗粒化性能及代谢特征的影响

在线全文

学校读者我要写书评

暂无评论

中国环境科学 2024年第2期44卷 686-698页

作者：陈希胡彬张瑞峰宫延哲蔡虎林曹银焕杨文浩穆瑞花西安工程大学城市规划与市政工程学院陕西西安710048 西安净水处理有限责任公司陕西西安710061 西安工程大学环境与化学工程学院陕西西安710048

以60%乙酸钠和40%可溶性淀粉复合基质为碳源,考察表观气速对生物除磷污泥颗粒化性能及代谢特征的影响.结果表明,与小分子碳源不同,复杂碳源条件下生物除磷污泥的颗粒化由剪切力和碳源的胞内储存共同决定,污泥颗粒化进程与表观气速的大... 详细信息

以60%乙酸钠和40%可溶性淀粉复合基质为碳源,考察表观气速对生物除磷污泥颗粒化性能及代谢特征的影响.结果表明,与小分子碳源不同,复杂碳源条件下生物除磷污泥的颗粒化由剪切力和碳源的胞内储存共同决定,污泥颗粒化进程与表观气速的大小并不完全一致.R1表观气速最大(0.45cm/s),110d可实现颗粒化;R3表观气速最小(0.15cm/s),190d实现颗粒化,进程慢于R1,但快于R2(表观气速0.30cm/s).降低表观气速污泥的丝状菌含量依次增多,紧密型胞外聚合物(TB-EPS)的疏水性依次降低;但系统更易实现厌氧饱食和好氧饥饿,聚羟基烷酸酯(PHAs)厌氧合成量依次升高,R1、R2、R3分别为2.28、8.16、23.96mg/gVSS.16SrRNA基因高通量测序表明,随着表观气速的降低,具有水解发酵功能的绿弯菌门(Chloroflexi)的丰度依次升高,分别为7.86%、8.77%和32.74%.在属水平,传统聚糖菌Candidatus_Competibacter是污泥颗粒化的核心菌群,R1较高的表观气速有利于该菌的维持和优势增殖,污泥颗粒化进程最快.R3表观气速最低,水解发酵功能菌群Kouleothrix(1851型丝状菌,属于绿弯菌门)大量生长(丰度10.44%),通过提供丝状骨架和小分子碳源促进Candidatus_Competibacter的优势增殖(丰度25.73%),加快了污泥的颗粒化.

关键词：复杂碳源颗粒污泥表观气速胞内储存菌群结构影响

基于TOPSIS法建立注射用齐拉西酮药物利用评价标准及其应用结果分析

在线全文

学校读者我要写书评

暂无评论

中国医院药学杂志 2024年第7期44卷 810-814页

作者：戴彪夏清荣柏同健曹银张元元安徽医科大学附属心理医院药剂科安徽合肥230022 合肥市第四人民医院药剂科安徽合肥230022 安徽省精神卫生中心精神药理研究室安徽合肥230022. 安徽省精神心理疾病临床医学研究中心安徽合肥230022 安徽医科大学第一附属医院神经内科安徽合肥230022

目的:基于TOPSIS法建立注射用齐拉西酮药物利用评价(DUE)标准,评价其临床使用合理性。方法:以注射用齐拉西酮药品说明书为基础,参考相关指南和专家共识,通过专家咨询法建立注射用齐拉西酮DUE标准,同时采用加权TOPSIS法回顾性分析安徽省... 详细信息

目的:基于TOPSIS法建立注射用齐拉西酮药物利用评价(DUE)标准,评价其临床使用合理性。方法:以注射用齐拉西酮药品说明书为基础,参考相关指南和专家共识,通过专家咨询法建立注射用齐拉西酮DUE标准,同时采用加权TOPSIS法回顾性分析安徽省精神卫生中心2022年1—12月使用注射用齐拉西酮的归档病例进行合理性评价。结果:共纳入269份病例,完全符合评价标准仅31例(11.52%),注射用齐拉西酮不合理应用常见于超适应证(46.47%)、禁忌证(0.37%)、用药疗程(9.29%)、辅助检查及实验室检查(32.71%)、药物相互作用(13.01%)、特殊人群(2.97%)和药物序贯(7.06%)。结论:所建立的注射用齐拉西酮DUE标准可用于注射用齐拉西酮临床合理性评价。

关键词：注射用齐拉西酮药物利用评价标准合理用药专家咨询法加权TOPSIS法

Forces Driving Changes in Cultivated Land and Management Countermeasures in the Three Gorges Reservoir Area,China

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2013年第1期10卷 149-162页

作者： cao yin-gui BAI Zhong-ke ZHOU Wei WANG Jing School of Land Science and Technology China University of Geosciences Key Laboratory of Land Reconsolidation and Rehabilitation Ministry of Land and Resources Key Laboratory of Land Use Ministry of Land and Resources

The Three Gorges project accelerates economic development in the Three Gorges Reservoir *** paper aimed to investigate the distribution,changes and features of cultivated land in this area,analyze the forces driving the changes in cultivated land area,and propose the countermeasures for cultivated land *** matrix was used to analyze the features of cultivated land changes,and quantitative analysis and qualitative analysis were adopted to research the driving forces according to the features of cultivated land *** land in the Three Gorges Reservoir Area mainly lay to the northwest of the Yangtze River,especially the upper *** areas of cultivated land increased from 1996 to 1999,then decreased from 2000 to 2006,and finally increased again from 2007 to *** important forces driving changes in cultivated land included government policies,employment and food security,increasing construction land,agriculture structure adjustment,land rearrangement,*** cultivated land management,firstly,it is necessary to insist on the principle of cultivated land protection,standardize land exploitation and strictly restrict the transformation of cultivated land into non-farming ***,land rearrangement must be implemented,which can not only increase the area of the cultivated land,but also improve the quality of the cultivated ***,it is feasible to intensify eco-agriculture construction to increase the quantity and quality of cultivated ***,it is helpful to improve the traditional agriculture production methods to promote cultivated land ***,it is important to propagandize cultivated land protection and realize the enormous pressure of cultivated land shortage,making more people obligated to protect cultivated land.

关键词： Land use change Driving force Management countermeasure Cultivated land Three Gorges Reservoir Area

UPLC-MS/MS法测定人血清中曲唑酮浓度及其临床个体化用药

在线全文

学校读者我要写书评

暂无评论

中国药物警戒 2024年第9期21卷 991-997页

作者：曹银周旋戴彪邓逸芸闫春宇单锋夏清荣梁俊安徽医科大学附属心理医院合肥市第四人民医院药剂科安徽省精神卫生中心精神药理研究室安徽合肥230022

目的建立超高效液相串联质谱法(UPLC-MS/MS)测定患者血清中曲唑酮浓度,并用于曲唑酮的临床个体化用药。方法色谱柱为MSCB-2A(2.1 mm×50 mm,2.5μm);流动相为甲醇(B)-水(A,含0.01%氨水),梯度洗脱(梯度设置为0~0.2 min,55%B;0.2~2.0 mi... 详细信息

目的建立超高效液相串联质谱法(UPLC-MS/MS)测定患者血清中曲唑酮浓度,并用于曲唑酮的临床个体化用药。方法色谱柱为MSCB-2A(2.1 mm×50 mm,2.5μm);流动相为甲醇(B)-水(A,含0.01%氨水),梯度洗脱(梯度设置为0~0.2 min,55%B;0.2~2.0 min,55%~95%B;2.0~2.5 min,95%~95%B;2.5~2.6 min,95%~55%B;2.6~3.0 min,55%~55%B),流速0.5 m L·min^(-1),柱温40℃,进样量0.1μL;离子源:电喷雾离子源;电离模式:正离子模式。血清经乙腈沉淀蛋白,地西泮为内标,对本方法的专属性、标准曲线和定量下限、精密度与回收率、基质效应和稳定性进行相应的考察。同时将该方法应用于16例使用曲唑酮患者的血药浓度测定,并对检测结果进行分析,给出相应的干预意见。结果血清中曲唑酮在10.0~1 500.0 ng·m L^(-1)内线性关系良好(R2=0.999 4);低、中、高3组不同质控浓度(50.0、400.0、1 000.0 ng·m L^(-1))日内和日间精密度的相对标准偏差(RSD)均小于7%,准确度为91.90%~98.67%;低、中、高浓度的曲唑酮血清在常温下4 h、2~8℃冰箱冷藏24 h、长期冷冻3个月以及反复冻融循环条件下稳定性良好,在各条件下准确度为95.04%~105.78%。该法已成功应用于曲唑酮临床样本治疗药物监测。结论 UPLC-MS/MS法检测曲唑酮血药浓度具有快速简便、稳定准确、灵敏度高、污染小等优点,该法可应用于曲唑酮临床个体化用药。

关键词：曲唑酮 UPLC-MS/MS 治疗药物监测血药浓度人血清个体化用药

A Bubble Column Dehumidifier using Ionic Liquid Desiccant for Low-Humidity Industries:Insights into Transfer Processes Integrating Experiment and CFD Modelling

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2024年第6期33卷 2348-2371页

作者： cao Bowen yin Yonggao SAITO Kiyoshi School of Energy and Environment Southeast University School of Fundamental Science and Engineering Waseda University Department of Applied Mechanics and Aerospace Engineering Waseda University

Liquid desiccant deep dehumidification（LDDD） is an excellent energy-saving technology for low-humidity *** liquids（ILs） are favored as optimal working fluids for LDDD,owing to their low vapor pressure,non-crystallization,and *** combined application of IL desiccant with the bubble column has been proven to effectively improve deep *** present work focuses specifically on the insights into air-liquid transfer processes in bubble column dehumidifier using ionic liquid *** effect of operating parameters on volumetric transfer coefficient is examined based on the experimental ***,the bubble swarms meso-scale flow structure is predicted using computational fluid dynamics coupled with a population balance model（CFD-PBM）.Besides,the structure-activity relationship between meso-scale flow structure and transfer performance is *** results indicated a notable phenomenon of bubble aggregation/breakage in the moist air-IL desiccant bubbly deep dehumidification（MA-ILD BDD）system,with a specific interfacial area is basically less than 40 ***,a decrease in solution temperature,correlated with a significant increase in viscosity,leads to larger turbulent eddies and a slower breakage ***,a high transfer potential difference enhances heat and mass transfer coefficients at lower solution temperatures,with the mass transfer coefficient at 4℃ being approximately three times that at 10℃.As the superficial velocity changes,the specific interfacial area and heat and mass transfer coefficients have a positive synergistic effect on volumetric transfer ***,this synergistic effect is reversed with variations in solution *** study aims to clarify the air-liquid transfer mechanism in bubble column dehumidifier using IL desiccant.

关键词： bubble column deep dehumidification heat and mass transfer ionic liquid liquid desiccant low-humidity industries

肌松监测背景下深度肌松低气腹压技术在腹腔镜手术中的应用效果评价

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

现代实用医学 2024年第7期36卷 883-885页

作者：陈勇杰李勇曹寅张益维宁波大学附属第一医院宁波315010 宁波市第九医院

目的观察肌松监测(TOF)背景条件下深度肌松低气腹压技术在腹腔镜手术中的应用效果。方法收集2019年6月至2021年12月宁波大学附属第一医院收治的行腹腔镜胃癌根治术患者120例,采用随机数字表法分为观察组和对照组,每组各60例。观察组采... 详细信息

目的观察肌松监测(TOF)背景条件下深度肌松低气腹压技术在腹腔镜手术中的应用效果。方法收集2019年6月至2021年12月宁波大学附属第一医院收治的行腹腔镜胃癌根治术患者120例,采用随机数字表法分为观察组和对照组,每组各60例。观察组采用深度肌松下低气腹压技术,对照组采用常规肌松与气腹压技术。比较两组麻醉时间、手术时间、拔管时间、麻醉复苏室(PACU)时间及肠道功能恢复时间,出复苏室时动脉血二氧化碳分压(PaCO_(2))、动脉血氧分压(PaO_(2)),以及术后低氧血症、恶心呕吐、补救镇痛及肩痛等并发症发生率。结果观察组3例,对照组3例退出研究。与对照组比较,观察组需要补救镇痛患者更少,术后恶心呕吐发生率更低,肠道功能恢复时间更短(均P<0.05)。结论TOF背景条件下,深度肌松不会增加术后低氧血症发生率,也不会延长麻醉、手术及苏醒时间,反而能减轻术后疼痛,降低术后恶心呕吐发生率,促进术后肠道功能恢复。

关键词：腹腔镜肌松监测效果

A Depth Video Coding In-Loop Median Filter Based on Joint Weighted Sparse Representation

在线全文

学校读者我要写书评

暂无评论

Wuhan University Journal of Natural Sciences 2016年第4期21卷 351-357页

作者： Lü Haitao yin cao CUI Zongmin HU Jinhui School of Information Science and Technology Jiujiang University National Engineering Research Center for Multimedia Software/School of Computer Wuhan University

The existing depth video coding algorithms are generally based on in-loop depth filters, whose performance are unstable and easily affected by the outliers. In this paper, we design a joint weighted sparse representation-based median filter as the in-loop filter in depth video codec. It constructs depth candidate set which contains relevant neighboring depth pixel based on depth and intensity similarity weighted sparse coding, then the median operation is performed on this set to select a neighboring depth pixel as the result of the filtering. The experimental results indicate that the depth bitrate is reduced by about 9% compared with anchor method. It is confirmed that the proposed method is more effective in reducing the required depth bitrates for a given synthesis quality level.

关键词： depth video coding virtual view synthesis joint weighted sparse representation

2018-2022年青海省主要湖泊蓄水量时空变化数据集

在线全文

学校读者我要写书评

暂无评论

中国科学数据（中英文网络版） 2024年第1期9卷 314-327页

作者：张怀文曹引赵红莉蒋云钟严登明赵慧子兰州交通大学测绘与地理信息学院兰州730070 甘肃省地理国情监测工程实验室兰州730070 地理国情监测技术应用国家地方联合工程研究中心兰州730070 中国水利水电科学研究院水资源研究所北京100038 水利部数字孪生流域重点实验室北京100038 黄河勘测规划设计研究院有限公司郑州450003

青海省是中国西北部重要的生态功能区,水资源总量丰富,但时空分布极不均匀,且由于气候、地理环境等因素的影响,大部分湖泊长期缺乏监测。而湖泊作为地表水水资源的重要载体,是研究气候变化和人类活动对水循环过程影响的重要指示器。国... 详细信息

青海省是中国西北部重要的生态功能区,水资源总量丰富,但时空分布极不均匀,且由于气候、地理环境等因素的影响,大部分湖泊长期缺乏监测。而湖泊作为地表水水资源的重要载体,是研究气候变化和人类活动对水循环过程影响的重要指示器。国产高分一号、六号卫星宽幅相机空间分辨率为16 m,组网运行可实现2天重复观测,可以高频次获取地表水体面积;ICESat-2激光测高数据具备厘米级的测高精度,可以获取高精度的地表水体测高水位。本数据集基于GF-1/6WFV水体面积和ICESat-2测高水位构建青海省湖泊蓄水量遥感监测模型,通过遥感手段对青海省湖泊蓄水量进行时空变化监测。经验证,本数据集中湖泊蓄变量监测精度总体优于93%,满足湖泊蓄水量时空变化遥感监测需求。本数据集在时间尺度上涵盖2018-2022年,共计60期月度监测结果;空间尺度上覆盖了青海省面积大于30 km^(2)的33个湖泊,主要集中分布在青海省西部、北部、东南部,可为青海省湖泊、水文与气候变化过程监测、水资源动态评价、优化水资源管理与调度提供基础数据支撑。

关键词：湖泊蓄水量 GF-1/6 WFV ICESat-2 青海省 2018-2022年

Expression and clinical significance of S100A2 and p63 in esophageal carcinoma

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第33期15卷 4183-4188页

作者： Li-Yu cao Yu yin Hao Li Yan Jiang Hong-Fu Zhang Department of Pathology Anhui Medical University Hefei 230032 Anhui Province China

AIM： TO investigate the expression and clinical significance of S100A2 mRNA and protein, p63 protein in esophageal squamous cell carcinoma （ESCC） and their roles in carcinogenesis and progression of esophageal carcinoma （EC）. METHODS： Immunohistochemical staining （S-P method） for S100A2 and p63 protein were performed in 40 samples of ESCC and 40 samples of normal esophageal mucosa. In situ hybridization （ISH） was used to detect the expression of S100A2 mRNA. RESULTS： Expression of S100A2 mRNA in ESCC was positive in 77.5% of samples, which was lower than that in normal mucosa （100%） by ISH （P = 0.002）. The expression level of S100A2 mRNA was closely related to differentiation and and node-metastasis （P = 0.012, P = 0.008）. Expression of $100A2 protein was positive in 72.5% of ESCC samples and expression of p63 protein was positive in 37.5% of ESCC samples, and was lower than that in normal mucosa （100%）（P = 0.000）. The expression of S100A2 protein was correlated with the differentiation and node-metastasis （P = 0.007, P = 0.001）, but no relationship was observed between the expression of p63 protein and clinical pathological manifestations. S100A2 protein was positively correlated with the expression of S100A2 mRNA, and negatively associated with the expression of p63 protein （P = 0.000, P = 0.002）. CONCLUSION： S100A2 and p63 protein both play important roles in the carcinogenesis of ESCC. An investigation into the combined expression of S100A2 and p63 may be helpful in early diagnosis and in evaluating the prognosis of ESCC.

关键词： Immunohistochemistry In situ hybridization Esophageal carcinoma p63 S100A2