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Probing the Gamma-Ray Emission Region of Five TeV Flat Spectrum Radio Quasars

Research in Astronomy and Astrophysics 2024年第6期24卷 156-169页

作者： Hu-Bing Xiao Hai-Tao cao Rui Xue jin-Ting Cai Ge-Ge Wang Marina Manganaro Shao-Hua Zhang Zhi-Hao Ouyang Li-Ping Fu Jun-Hui Fan Shanghai Key Lab for Astrophysics Shanghai Normal UniversityShanghai 200234China School of Information Engineering Guangzhou Panyu PolytechnicGuangzhou 511483China Department of Physics Zhejiang Normal UniversityJinhua 321004China College of Mathematics and Physics Guangxi Minzu UniversityNanning 530006China Key Laboratory of Cosmology and Astrophysics(Liaoning) College of SciencesNortheastern UniversityShenyang 110819China Department of Physics University of RijekaRijeka 51000Croatia Center for Astrophysics Guangzhou UniversityGuangzhou 510006China Key Laboratory for Astronomical Observation and Technology of Guangzhou Guangzhou 510006China Astronomy Science and Technology Research Laboratory of Department of Education of Guangdong Province Guangzhou 510006China

The location ofγ-ray emission of blazars remains a contested topic,inspiring the development of numerous investigative techniques to address this *** this work,we analyzed Fermiγ-ray light curves in the GeV and MeV bands,employing the discrete cross-correlation function method to discern time lags between the two *** 4C+21.35,Ton 599,B21420+32,and PKS 1510-089,we identified a time lag spanning several days,while for PKS 1441+25,the time lag was not statistically *** results imply that the soft photons necessary for inverse Compton scattering predominantly originate from the dusty torus in the first four sources,whereas for PKS1441+25,they seem to be sourced mainly from the broad-line *** analysis of the opacity(τγγ)and the GeV spectra study supports the conclusion that the location of the dissipation region must be beyond the BLR to avoid significant ***,for PKS 1441+25,the emission region is also posited to lie outside yet proximate to the *** parameters of describing the emission region were obtained by fitting broadband spectral energy distribution with contemporaneous observation *** findings suggest that for the five TeV FSRQs,during Te V flaring events,the jet appears to maintain an equilibrium between the energy density of the magnetic field and that of the particles for all investigated sources,with the exceptions of 4C+21.35 and PKS1441+*** terms of the overall jet power,particle energy is the dominant contributor,and the observed blazar radiation cannot be solely attributed to the magnetic field,except in the case of 4C+***,magnetic reconnection is unlikely to be the primary mechanism behind particle acceleration in these systems.

关键词： galaxies:active gamma-rays:galaxies galaxies:jets

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CO_(2)辐射效应与生理效应对气候系统影响异同的模拟研究

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气候变化研究进展 2024年第2期20卷 170-181页

作者：吴星怡曹龙浙江大学地球科学学院大气科学系杭州310027

基于CESM地球系统模式,模拟研究不同CO_(2)浓度变化情景下,在快响应阶段和平衡阶段,CO_(2)通过影响大气辐射传输过程的辐射效应和通过影响植被气孔的生理效应对气候系统的影响和作用机制异同。试验结果表明,在CO_(2)倍增的情况下,CO_(2... 详细信息

基于CESM地球系统模式,模拟研究不同CO_(2)浓度变化情景下,在快响应阶段和平衡阶段,CO_(2)通过影响大气辐射传输过程的辐射效应和通过影响植被气孔的生理效应对气候系统的影响和作用机制异同。试验结果表明,在CO_(2)倍增的情况下,CO_(2)辐射效应和生理效应都会引起全球地表的增温。辐射效应在两个阶段的地表增温中均起主导作用,而在快响应阶段,生理效应在全球陆表增温中贡献率达到了(27.5±0.9)%。CO_(2)辐射效应和生理效应对全球水循环的影响有明显差异。在平衡阶段,CO_(2)辐射效应使全球地表蒸散增加(5.2±0.1)%,径流量增加(8.0±0.4)%;而CO_(2)生理效应使全球地表蒸散量下降(3.9±0.1)%,径流量增加(10.1±0.4)%。在快响应阶段,生理效应在蒸散量的变化中占据主导作用。在CO_(2)倍增试验基础上,又进行了大气CO_(2)浓度分别为400×10^(-6)、600×10^(-6)、800×10^(-6)、1000×10^(-6)的模拟试验。随着CO_(2)浓度的增加,受辐射效应影响,地表温度、蒸散量和降水量出现持续增加,但增幅有所放缓;受CO_(2)生理效应影响,地表蒸散量持续减少,下降幅度并未出现明显变化。CO_(2)辐射效应和生理效应的协同作用具有非线性。对于地表温度、降水和蒸散等变量,CO_(2)辐射效应和生理效应共同作用引起的变化与两者单独作用时引起的变化之和存在差异,且这种差异随着CO_(2)浓度的增加越来越显著。

关键词：气候变化 CO_(2)辐射效应植被气孔 CO_(2)生理效应

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先进制造业与信息服务业融合的产业升级效应

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经济地理 2024年第4期44卷 121-130页

作者：曹兴刘新琨中南大学商学院湖南长沙410083 湖南第一师范学院湖南长沙410205

文章基于中国30个省份2009—2021年面板数据,运用耦合协调度模型和熵权法,测算了先进制造业与信息服务业耦合发展水平以及先进制造业升级水平;采用固定效应和随机效应模型,对先进制造业与信息服务业耦合发展水平的产业升级效应进行实证... 详细信息

文章基于中国30个省份2009—2021年面板数据,运用耦合协调度模型和熵权法,测算了先进制造业与信息服务业耦合发展水平以及先进制造业升级水平;采用固定效应和随机效应模型,对先进制造业与信息服务业耦合发展水平的产业升级效应进行实证检验。研究发现:(1)中国先进制造业与信息服务业的协调发展总体上对先进制造业产生正向的产业升级效应。从区域层面来看,北部沿海地区升级效应相对更强,除南部沿海地区外的其他区域升级效应均显著;(2)两大产业融合发展呈现出动态演进的过程,耦合协调度逐步提高,且沿海区域的产业耦合协调发展水平普遍优于内陆地区的发展水平;(3)中国先进制造业升级水平从2016年开始出现了明显的上升趋势,整体上由2009年的0.249提高到了2021年的0.503。为进一步推动先进制造业升级,政府应鼓励先进制造业与信息服务业的深度互动融合,建立融合型产业新体系,完善融合型人才培养机制,加强制造业数字化转型关键技术的研究,增强产业融合技术发展新动能。

关键词：先进制造业信息服务业融合发展产业升级耦合协调度模型数字化转型科技创新

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The effect of bladder function on the efficacy of transurethral prostatectomy in patients with benign prostatic hyperplasia:a retrospective,single-center study

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Asian Journal of Andrology 2024年第1期26卷 112-118页

作者： jin Li Xian-Yan-Ling Yi Ze-Yu Chen Bo Chen Yin Huang Da-Zhou Liao Pu-Ze Wang De-Hong cao Jian-Zhong Ai Liang-Ren Liu West China School of Medicine Sichuan UniversityChengdu 610041China Department of Urology Institute of UrologyWest China HospitalSichuan UniversityChengdu 610041China

We investigated the impact and predictive value of bladder function in patients with benign prostatic hyperplasia(BPH)on the efficacy of transurethral ***,imaging,and urodynamic data of patients who underwent transurethral prostatectomy at West China Hospital of Sichuan University(Chengdu,China)from July 2019 to December 2021 were ***-up data included the quality of life(QoL),International Prostate Symptom Score(IPSS),and IPSS storage and voiding(IPSS-s and IPSS-v).Moreover,urinary creatinine(Cr),nerve growth factor(NGF),brain-derived neurotrophic factor(BDNF),and prostaglandin estradiol(PGE2)were measured in 30 patients with BPH and 30 healthy *** indicators were determined by subgroup analyses and receiver operating characteristic(ROC)curve *** the 313 patients with BPH included,patients with severe micturition problems had more improvements but higher micturition grades postoperatively than those with moderate ***,good bladder sensation,compliance,and detrusor contractility(Dc)were predictors of low postoperative IPSS and *** urinary concentrations of BDNF/Cr,NGF/Cr,and PGE2/Cr in patients were significantly higher than those in healthy participants(all P<***1).After evaluation,only DC was significantly related to both urinary indicators and postoperative recovery of *** with good DC,as predicted by urinary indicators,had lower IPSS and IPSS-v than those with reduced DC at the 1st month postoperatively(both P<0.05).In summary,patients with impaired bladder function had poor *** combined levels of urinary BDNF/Cr,NGF/Cr,and PGE2/Cr in patients with BPH may be valid predictors of preoperative bladderfunction and postoperative recovery.

关键词： BPH function of bladder IPSS:urodynamics

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传播政治经济学国际视野与在地经验的思考

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南京大学学报（哲学．人文科学．社会科学） 2024年第2期61卷 109-113页

作者：曹晋复旦大学新闻学院上海市200433

近年来,在数字化变革的浪潮中跨学科融合发展的趋势愈发明显,传播政治经济学作为政治经济学批判理论与传播学、社会学、文化研究等学科的交叉研究领域,其重要性日益彰显,从媒介产业的市场结构分析到平台资本的批判性反思,从日常生活的... 详细信息

近年来,在数字化变革的浪潮中跨学科融合发展的趋势愈发明显,传播政治经济学作为政治经济学批判理论与传播学、社会学、文化研究等学科的交叉研究领域,其重要性日益彰显,从媒介产业的市场结构分析到平台资本的批判性反思,从日常生活的文化表征考察到社会权力结构的深刻揭示,均有传播政治经济学的介入并有力推动了相关研究。《南京大学学报》编辑部于2023年12月15—17日在南京举办了“传播政治经济学理论与实践”学术工作坊,邀请国内在相关领域耕耘多年的学者,对传播政治经济学的国际视野与在地经验、理论面向与阐释维度、传播学自主知识体系建构、传播政治经济学与文化研究的接合趋势等重大理论问题以及数字平台、数字游民等具体的实践问题进行了深入热烈的探讨。本期本专栏推出六篇笔谈文章,是此次学术工作坊研讨成果的展示,在一定程度上显示了该领域的多元面貌、理论前沿及其实践应用,希望以此推动这一新兴交叉学科领域的发展创新。

关键词：传播政治经济学工作坊国际视野文化表征媒介产业在地经验南京大学学报理论与实践

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RIS辅助FSO/RF混构系统性能研究

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激光与光电子学进展 2024年第15期61卷 1-8页

作者：包朝园曹阳彭小峰邢雯珺重庆理工大学电气与电子工程学院

为了研究可重构智能表面（RIS）辅助自由空间光（FSO）/射频（RF）混构系统的性能，在RF链路中考虑同信道干扰问题的影响。RIS能够解决RF链路无法完成视距通信的问题，从而提升通信系统性能。FSO链路服从双广义伽马分布，并考虑指向误... 详细信息

为了研究可重构智能表面（RIS）辅助自由空间光（FSO）/射频（RF）混构系统的性能，在RF链路中考虑同信道干扰问题的影响。RIS能够解决RF链路无法完成视距通信的问题，从而提升通信系统性能。FSO链路服从双广义伽马分布，并考虑指向误差的影响，RF链路服从瑞利分布，在中继节点处采用译码转发协议，减少噪声对传输信号的干扰。推导了系统端到端瞬时信噪比的累积分布函数，在此基础上，进一步推导了该系统的中断概率和平均误码率的闭合公式。仿真结果表明，该系统方案在弱湍流和中湍流强度下性能提升较为明显。在弱湍流强度下，RIS可以有效抵抗干扰对RF链路的影响，从而提升系统性能。

关键词：同信道干扰可重构智能表面中断概率平均误码率

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Entanglement quantification via weak measurements assisted by deep learning

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Photonics Research 2024年第4期12卷 712-719页

作者： MU YANG YA XIAO ZE-YAN HAO YU-WEI LIAO JIA-HE cao KAI SUN EN-HUI WANG ZHENG-HAO LIU YUTAKA SHIKANO jin-SHI XU CHUAN-FENG LI GUANG-CAN GUO CAS Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026China College of Physics and Optoelectronic Engineering Ocean University of ChinaQingdao 266100China CAS Center for Excellence in Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China Hefei National Laboratory University of Science and Technology of ChinaHefei 230088China Electric Power Research Institute State Grid Anhui Electric Power Co.Ltd.Hefei 230601China Institute of Systems and Information Engineering University of TsukubaIbaraki 305-8573Japan Center for Artificial Intelligence Research University of TsukubaIbaraki 305-8577Japan Graduate School of Science and Technology Gunma UniversityGunma 371-8510Japan Institute for Quantum Studies Chapman UniversityOrangeCalifornia 92866USA JST PRESTO Saitama 332-0012Japan

Entanglement has been recognized as being crucial when implementing various quantum information ***, quantifying entanglement for an unknown quantum state requires nonphysical operations or post-processing measurement data. For example, evaluation methods via quantum state tomography require vast amounts of measurement data and likely estimation.

关键词： estimation quantum angle

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Enhancing m^(6)A modification in the motor cortex facilitates corticospinal tract remodeling after spinal cord injury

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Neural Regeneration Research 2025年第6期20卷 1749-1763页

作者： Tian Qin Yuxin jin Yiming Qin Feifei Yuan Hongbin Lu Jianzhong Hu Yong cao Chengjun Li Department of Spine Surgery and Orthopedics Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Key Laboratory of Organ Injury Aging and Regenerative Medicine of Hunan ProvinceChangshaHunan ProvinceChina National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Department of Sports Medicine Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Spinal cord injury typically causes corticospinal tract disruption. Although the disrupted corticospinal tract can self-regenerate to a certain degree, the underlying mechanism of this process is still unclear. N6-methyladenosine(m^(6)A) modifications are the most common form of epigenetic regulation at the RNA level and play an essential role in biological processes. However, whether m^(6)A modifications participate in corticospinal tract regeneration after spinal cord injury remains unknown. We found that expression of methyltransferase 14 protein(METTL14) in the locomotor cortex was high after spinal cord injury and accompanied by elevated m^(6)A levels. Knockdown of Mettl14 in the locomotor cortex was not favorable for corticospinal tract regeneration and neurological recovery after spinal cord injury. Through bioinformatics analysis and methylated RNA immunoprecipitation-quantitative polymerase chain reaction, we found that METTL14 regulated Trib2 expression in an m^(6)A-regulated manner, thereby activating the mitogen-activated protein kinase pathway and promoting corticospinal tract regeneration. Finally, we administered syringin, a stabilizer of METTL14, using molecular docking. Results confirmed that syringin can promote corticospinal tract regeneration and facilitate neurological recovery by stabilizing METTL14. Findings from this study reveal that m^(6)A modification is involved in the regulation of corticospinal tract regeneration after spinal cord injury.

关键词： corticospinal tract remodeling epigenetic regulations locomotor cortex m^(6)A modification methyltransferase 14 protein(METTL14) mitogen-activated protein kinase neural regeneration spinal cord injury syringin TRIB2

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Study on improving hematopoietic function of rats with blood deficiency syndrome by Shengxuebao mixture

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Traditional Medicine Research 2024年第8期9卷 35-46页

作者： Yan Shu Hong-Na Liu Yang Zhao jin-Yi cao Yue Chen Yi Qiao Hui Guo Zhi-Fu Yang College of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China Tsing Hua De Ren Xi’an Happiness Pharmaceutical Co. Ltd.Xi’an 710400China Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi’an 710000China State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration National Clinical Research Center for Oral DiseasesShaanxi Engineering Research Center for Dental Materials and Advanced ManufactureDepartment of PharmacySchool of Stomatologythe Fourth Military Medical UniversityXi’an 710000China

Background:Shengxuebao mixture(SXBM)is a novel herbal drug approved by China State Food and Drug Administration for the treatment of Leukopenia and iron deficiency anemia caused by radiotherapy and ***:To explore the mechanism of SXBM in treating blood deficiency syndrome(BDS).Firstly,network pharmacology and in vivo experiments were used to screen candidate targets and important signaling pathways of SXBM,GO functional enrichment and KEGG pathway analysis were ***,a BDS rat model was established to verify the results of the analysis of network pharmacological *** and routine peripheral blood examination were *** expressions of tumor necrosis factor-α,interleukin(IL)-6,HIF-1αand NF-κB were detected by Western blot,and the expressions of IL-6,IL-1βwere detected by ***:62 bioactive components,66 potential targets and 131 signaling pathways of BDS were successfully identified by network *** docking simulation techniques showed that key targets tumor necrosis factor-α,IL-6,IL-1βcan dock well with crucial components,and the BDS-related signaling pathways HIF-1 and JAK-STAT play a vital *** combined model experiment of acetylphenylhydrazine and cyclophosphamide showed that the model group had obvious blood deficiency,and the histopathology and blood routine were effectively restored after *** findings indicate that SXBM’s therapeutic effect on BDS primarily involves the mediation of the HIF-1α/NF-κB signaling pathway and the regulation of hematopoietic factor ***:This study not only affirmed the protective properties of SXBM against BDS but also provided insights into a potential mechanism for blood replenishment in the treatment of BDS using SXBM.

关键词： network pharmacology molecular docking technology blood deficiency syndrome hematopoietic factors HIF-1α/NF-κB

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TCGA-based analysis of oncogenic signaling pathways underlying oral squamous cell carcinoma

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Oncology and Translational Medicine 2024年第2期10卷 87-92页

作者： xing Gao Dan-Dan Liu jin-Zhong Liu Rui Wang Department of Prevention Hospital of StomatologyJilin UniversityChangchun 130021China

Background:Oral squamous cell carcinoma(OSCC)represents a prevalent malignancy in the oral and maxillofacial area,having a considerable negative impact on both the quality of life and overall survival of affected *** research endeavors to leverage bioinformatic approaches to elucidate oncogenic signaling pathways,with the ultimate goal of gaining deeper insights into the molecular underpinnings of OSCC pathogenesis,and thus laying the groundwork for the development of more effective therapeutic and preventive ***:Differential expression analysis was performed on mRNA data from tumor and normal tissue groups to identify genes associated with OSCC,using The Cancer Genome Atlas *** of oncogenic signaling pathways linked to differentially expressedmRNAs were made,and these results were presented visually using R software,using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes ***:GO and KEGG analyses of 2938 differentially expressed genes in OSCC highlighted their significant involvement in various biological ***,these processes were related to the extracellular matrix,structural organization,connective tissue development,and cell cycle ***:The comprehensive exploration of gene expression patterns provides valuable insights into potential oncogenic mechanisms in OSCC.

关键词： Oral squamous cell carcinoma Oncogenic signaling pathway Bioinformatics

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