检索结果-南通市图书馆

Efficacy and safety of Yiqi Peiyuan granules for improving the short-term prognosis of patients with acute kidney injury:A multicenter,double-blind,placebo-controlled,randomized trial

引用

Journal of Integrative Medicine 2024年第3期22卷 279-285页

作者： Jia-jia Wu tian-yi Zhang Ying-hui Qi Min-yan Zhu Yan Fang Chao-jun Qi Li-ou cao Ji-fang Lu Bo-han Lu Lu-min Tang Jian-xiao Shen Shan Mou Department of Nephrology Molecular Cell Lab for Kidney DiseaseShanghai Peritoneal Dialysis Research CenterUremia Diagnosis and Treatment CenterRenji Hospital Affiliated to Shanghai Jiaotong University School of MedicineShanghai 200127China Department of Nephrology Shanghai Pudong New Area Punan HospitalShanghai 200125China Department of Nephrology Ningbo Hangzhou Bay HospitalNingbo 315336Zhejiang ProvinceChina

Background:Yiqi Peiyuan(YQPY)prescription,a composite prescription of traditional Chinese medicine,has been used to prevent or delay the continued deterioration of renal function after acute kidney injury(AKI)in some institutions and has shown considerable ***:This is the first randomized controlled trial to assess efficacy and safety of YQPY for improving short-term prognosis in adult patients with ***,setting,participants and interventions:This is a prospective,double-blind,multicenter,randomized,and placebo-controlled clinical trial.A total of 144 enrolled participants were randomly allocated to two groups according to a randomization ***,caregivers and investigators assessing the outcomes were blinded to group *** in the YQPY group received 36 g YQPY granules twice a day for 28 *** in the placebo group received a placebo in the same dose as the YQPY *** outcome measures:The primary outcome was the change in the estimated glomerular filtration rate(eGFR)between baseline and after 4 and 24 weeks of *** secondary outcomes were the change of serum creatinine(Scr)level between baseline and after treatment,and the incidence of endpoint events,defined as eGFR increasing by more than 25%above baseline,eGFR>75 mL/min per1.73 m2or the composite endpoint,which was defined as the sum of patients meeting either of the above ***:Data from a total of 114 patients(59 in the YQPY group and 55 in the control group)were *** mean changes in eGFR and Scr in weeks 4 and 24 had no difference between the two *** further subgroup analysis(22 in the YQPY group and 31 in the control group),the mean change in eGFR after treatment for 4 weeks was 27.39 mL/min per 1.73 m2in the YQPY group and 5.78 mL/min per1.73 m2in the placebo group,and the mean difference between groups was 21.61 mL/min per 1.73 m2(P<0.001).Thirteen(59.1%)patients in the YQPY group and 5(16.1%)in the placebo g

关键词： Chinese herbal medicine Randomized controlled trial Acute kidney injury Renal function

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Velocity Aberration Effect of the CSST Main Survey Camera

引用

Research in Astronomy and Astrophysics 2024年第9期24卷 119-127页

作者： Hui-Mei Feng Zi-Huang cao Man ILam Ran Li Hao tian Xin Zhang Peng Wei Xin-Feng Li Wei Wang Hugh RAJones Mao-Yuan Liu Chao Liu National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000China University of Chinese Academy of Sciences Beijing 100049China Technology and Engineering Center for Space Utilization Chinese Academy of SciencesBeijing 100094China Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China Centre for Astrophysics University of HertfordshireHatfieldUK

In this study,we conducted simulations to find the geometric aberrations expected for images taken by the Main Survey Camera of the Chinese Space Station Telescope(CSST)due to its *** anticipated by previous work,our findings indicate that the geometric distortion of light impacts the focal plane's apparent scale,with a more pronounced influence as the size of the focal plane *** models suggest that the effect consistently influences the pixel scale in both the vertical and parallel *** apparent scale variation follows a sinusoidal distribution throughout one orbital *** reveal that the effect is particularly pronounced in the center of the Galaxy and gradually diminishes along the direction of ecliptic *** low ecliptic latitudes,the total aberration leads to about a 0.94 pixel offset(a 20 minute exposure)and a 0.26 pixel offset(a 300 s exposure)at the edge of the field of *** processings for the geometric effect during the CSST pre-and post-observation phases are presented.

关键词： astrometry telescopes Astronomical Instrumentation Methods and Techniques

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

商贸流通供应链数字化协同机制及其效果

引用

商业经济研究 2024年第20期 20-24页

作者：田甜曹颖重庆对外经贸学院重庆401520

企业数字化转型会受到供应链上下游企业的影响。本文选取2011-2022年沪深A股上市商贸流通企业作为研究样本,实证分析数字化转型在商贸流通供应链上的影响以及供应链上数字化协同带来的效果,得出如下结论:其一,商贸流通企业数字化转型会... 详细信息

企业数字化转型会受到供应链上下游企业的影响。本文选取2011-2022年沪深A股上市商贸流通企业作为研究样本,实证分析数字化转型在商贸流通供应链上的影响以及供应链上数字化协同带来的效果,得出如下结论:其一,商贸流通企业数字化转型会通过供应链进行传导,上下游企业如果进行了数字化转型,会带动相应的下游和上游企业进行数字化转型;其二,供应链上下游企业的数字化水平提升能够显著促进企业自身数字化水平提升,且下游客户企业的影响要大于上游供应企业的影响;其三,上下游企业在供应链中越重要,那么其数字化水平对企业的影响也越来越大;其四,企业供应链上下游企业都进行了数字化转型,数字化水平越高,越能实现供应链数字化协同,促进企业实现更高的财务绩效和创新绩效。最后,本文基于研究发现提出了针对性的政策建议。

关键词：商贸流通企业供应链数字化协同财务绩效创新绩效

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Review of 2D Bi_(2)X_(3)(X=S,Se,Te):from preparation to photodetector

引用

Rare Metals 2024年第6期43卷 2349-2370页

作者： Zhi Zeng Dong-Bo Wang Xuan Fang Jia-Mu cao Bing-Ke Zhang Jing-Wen Pan Dong-Hao Liu Si-Hang Liu Shu-Jie Jiao tian-Yuan Chen Gang Liu Lian-Cheng Zhao Jin-Zhong Wang Department of Optoelectronic Information Science School of Materials Science and EngineeringHarbin Institute of TechnologyHarbin 150001China Changchun University Science and Technology School of PhysicsThe State Key Laboratory of High Power Semiconductor LasersChangchun 130022China School of Astronautics Harbin Institute of TechnologyHarbin 150001China Center for High Pressure Science and Technology Advanced Research Shanghai 201203China

Detector has become an indispensable part of human *** increasing demand for photodetectors with high performance has promoted the research of novel *** the same time,with the development of rising material system,two-dimensional(2D)materials attract a lot of attention,while the suitable option for fabricating photodetector is still *** prospering of bismuth chalcogenides injected new vitality for material field,thereinto,the unique topological insulator characteristics make the research on bismuth selenide(Bi_(2)X_(3))and bismuth telluride(Bi_(2)X_(3)) intriguing.2D Bi_(2)X_(3) also exhibits unique features among various 2D materials,of which,the adjustable narrow energy band gap and polarization-sensitive photocurrent contribute to the promising application of high performance and broadband *** this review,from a bottom-up perspective,we summarize fundamental properties,synthesis method,photodetector performance of 2D Bi_(2)X_(3) based on the previous study,which provide an overall perspective of 2D Bi_(2)X_(3).Wherein,the section of the photodetector is specifically discu ssed with regard to pure Bi_(2)X_(3) photodetector and heterojunction photodetector.A brief summary and outlook were also explored in the end.

关键词： Bi_(2)X_(3) Preparation 2D Photodetector

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Insights into dammarane-type triterpenoid saponin biosynthesis from the telomere-totelomere genome of Gynostemma pentaphyllum

引用

Plant Communications 2024年第8期5卷 100-103页

作者： Lingling Yun Chuyi Zhang Tongtong Liang Yu tian Guoxu Ma Vincent Courdavault Sijie Sun Baiping Ma Ziqin Li Rucan Li Feng cao Xiaofeng Shen Jianhe Wei Ying Li Baolin Guo Chao Sun Institute of Medicinal Plant Development Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100193China Biomole cules et Biotechnologies Ve ge tales EA2106Universite de Tours37200 ToursFrance Beijing Institute of Radiation Medicine Beijing 100850China Present address:National Genomics Data Center Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijing 100101China

Dear Editor,Gynostemma pentaphyllum(Thunb.)Makino,a perennial climbing vine in the Cucurbitaceae family,has been widely used in traditional medicine for over 600 years(Blumert and Liu,1999).It serves as a valuable natural source of over 200 dammaranetype saponins with notable bioactive properties,including anti-cancer,cardioprotective,hepatoprotective,neuroprotective,and anti-diabetic activities(Li et al.,2016;Nguyen et al.,2021).

关键词： protective Gynostemma saponins

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

SFENet: Deep Neural Network with Separated Feature Extraction for Erythromycin Fermentation Production Prediction

SFENet: Deep Neural Network with Separated Feature Extractio...

引用

第35届中国过程控制会议

作者： Zhaoran Liu Chao Li Xiwei tian Yizhi cao Zijian tian Xinggao Liu School of Biotechnology East China University of Science and Technology

Large-scale erythromycin fermentation production is a complex process, and it is challenging to optimize the fed-batch strategy by only relying on manual control. Therefore, a prediction model is proposed to automatically predict key indicators in the erythromycin fermentation production process to assist human experts in formulating fed-batch strategy. The proposed model, SFENet, fully considers the time lag effect in monitoring data and the feature confusion problem in representation learning. The architecture of SFENet enables it to simultaneously learn temporal and variable correlations from the data and adaptively optimize the graph structure during the training process. Experimental results on real-world datasets show that SFENet reduces the prediction error by an average of 10% compared to previous state-of-the-art models and achieves excellent performance in both short-term and long-term scenarios. The proposed model is capable of being deployed in fermenters to assist in improving erythromycin production.

关键词： Erythromycin fermentation production Prediction models Neural networks

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

RuCo alloy nanoparticles embedded within N-doped porous two-dimensional carbon nanosheets:a high-performance hydrogen evolution reaction catalyst

引用

Tungsten 2024年第1期6卷 114-123页

作者： Jin-Hui Wang Shao-Wei Yang Fu-Bin Ma Yi-Ke Zhao Shi-Nuo Zhao Zheng-Yu Xiong Dong Cai Hai-Dong Shen Kai Zhu Qiu-Yu Zhang Yue-Ling cao tian-Shuai Wang He-Peng Zhang Research and Development Institute of Northwestern Polytechnical University in Shenzhen Shenzhen 518057China Xi’an Key Laboratory of Functional Organic Porous Materials School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’an 710129China School of Power and Energy Northwestern Polytechnical UniversityXi’an 710129China Chongqing Science and Technology Innovation Center of Northwestern Polytechnical University Chongqing 401135China

Developing cost-effective electrocatalysts with high activity and stability especially at high current density is of great significance for the large-scale commercial application of electrochemical water splitting to hydrogen production but still remains ***,we report an effective confinement pyrolysis strategy to fabricate embedded ruthenium-cobalt nanoclusters supported on N-doped porous two-dimensional carbon nanosheets(RuCo@CN).Markedly,the embedded structure can effectively prevent the migration,agglomeration,and leaching of nanoparticles,thus endowing the RuCo@CN catalyst with high *** be exact,high stability with up to 650 h can be achieved at high current density(-500 and-1000 mA·cm^(-2)).Besides,the RuCo@CN catalysts also exhibit highly reactive with low overpotentials of only 11mV at-10 mA·cm^(-2).Density functional theory calculations reveal that the introduction of cobalt reduces the decomposition barrier of H_(2)O for RuCo@CN alloy,thus promoting hydrogen evolution reaction.

关键词： Hydrogen evolution reaction Confinement pyrolysis strategy Mosaic structure Stability

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The protective effects of fermented vinegar on acute alcohol-induced hepatic and neuro-toxicity by regulating ethanol metabolism and gut microbiota

引用

Food Science and Human Wellness 2024年

作者： Yuan Meng Yunfan Liu Ting Xia Beibei Geng Yinglei tian Hailong cao Jin Yan Xiaoqi Pang Kai Liang Yufeng Yan Min Wang State Key Laboratory of Food Nutrition and Safety， Key Laboratory of Industrial Fermentation Microbiology， College of Biotechnology， tianjin University of Science and Technology Department of Gastroenterology and Hepatology， General Hospital， tianjin Medical University， National Key Clinical Specialty， tianjin Institute of Digestive Diseases， tianjin Key Laboratory of Digestive Diseases Shanxi Provincial Key Laboratory for Vinegar Fermentation Science and Engineering， Shanxi Zilin Vinegar Industry Co.， Ltd.

Alcohol abuse constitutes a significant health hazard， leading to various organ damage， notably the liver and brain. Shanxi aged vinegar (SAV) is one of the famous fermented and functional foods containing a variety of bioactive ingredients with beneficial effects on the human body. This study aimed to explore the potential protective effect of SAV in alleviating acute alcohol intoxication (AAI) in mice. It was found that SAV at 2.5 mg/kg BW effectively ameliorated the decline in behavioral abilities following alcohol consumption， characterized by a shortened sobering period. SAV reduces alcohol-induced liver damage by inhibiting hepatic function enzymes and oxidative stress levels. Additionally， SAV mitigated the overactivation of microglia and the downregulation of neurotransmitter levels (AchE， 5-HT， and DA)， thereby reducing ethanol-induced brain damage. Meanwhile， SAV significantly decreased concentrations of alcohol and acetaldehyde in the blood and increased ADH and ALDH activities in the liver， indicating enhancement of ethanol metabolism. Moreover， we found that some gut microbiota including Verrucomicrobiota， Akkermansia， and Enterococcus were downregulated after SAV treatment in mice with AAI. These bacteria showed a negative correlation with anti-oxidative markers (GSH and CAT) and enzymes related to ethanol metabolism pathways (ADH and ALDH)， and a positive correlation with hepatic function markers (ALT， AST， and MDA)， alcohol metabolites (alcohol and acetaldehyde) and neurotransmitters (AchE， 5-HT， and DA). However， Bacteroidota， norank＿f＿Muribaculaceae， and Alistipes exhibited the opposite direction. These findings suggest that SAV possesses protective effects against hepatic and neuro-toxicity， and could be a potential functional food for AAI prevention.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

A CNN-Based Single-Stage Occlusion Real-Time Target Detection Method

引用

Journal of Intelligent Learning Systems and Applications 2024年第1期16卷 1-11页

作者： Liang Liu Nan Yang Saifei Liu Yuanyuan cao Shuowen tian tiancheng Liu Xun Zhao Rizhao Power Supply Company State Grid Shandong Electric Power Company Rizhao China School of Automation Beijing Information Science and Technology University Beijing China

Aiming at the problem of low accuracy of traditional target detection methods for target detection in endoscopes in substation environments, a CNN-based real-time detection method for masked targets is proposed. The method adopts the overall design of backbone network, detection network and algorithmic parameter optimisation method, completes the model training on the self-constructed occlusion target dataset, and adopts the multi-scale perception method for target detection. The HNM algorithm is used to screen positive and negative samples during the training process, and the NMS algorithm is used to post-process the prediction results during the detection process to improve the detection efficiency. After experimental validation, the obtained model has the multi-class average predicted value (mAP) of the dataset. It has general advantages over traditional target detection methods. The detection time of a single target on FDDB dataset is 39 ms, which can meet the need of real-time target detection. In addition, the project team has successfully deployed the method into substations and put it into use in many places in Beijing, which is important for achieving the anomaly of occlusion target detection.

关键词： Real-Time Mask Target CNN (Convolutional Neural Network) Single-Stage Detection Multi-Scale Feature Perception

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

以神经系统损伤为首发症状的2例原发性干燥综合征报道

引用

上海交通大学学报（医学版） 2024年第6期44卷 795-800页

作者：姚莉田沃土曹立安徽医科大学附属宿州医院神经内科宿州234000 上海交通大学医学院附属第六人民医院神经内科上海200233 上海市神经系统罕见疾病生物样本库和精准诊断专业技术服务平台上海200233

目的·总结以神经系统损伤为首发症状的2例原发性干燥综合征(primary Sjögren's syndrome,pSS)患者的临床特点并复习相关文献。方法·对以神经系统受累为首发症状的2例pSS患者的临床表现、实验室检查结果、影像学检查结果、唇腺活检结... 详细信息

目的·总结以神经系统损伤为首发症状的2例原发性干燥综合征(primary Sjögren's syndrome,pSS)患者的临床特点并复习相关文献。方法·对以神经系统受累为首发症状的2例pSS患者的临床表现、实验室检查结果、影像学检查结果、唇腺活检结果、治疗效果等进行总结和分析。结果·病例1,女性,自50岁起出现进行性行走不稳伴下肢远端感觉障碍,表现为痉挛步态、感觉性共济失调、传导束性感觉障碍和二便障碍;58岁起无法独立行走。实验室检查提示抗核抗体阳性(1∶1000着丝点型),抗干燥综合征抗原A(SSA)/Ro-52抗体、抗SSA/Ro-60抗体、抗着丝点抗体阳性;唇腺活检可见唾液腺组织、导管间及小叶内淋巴细胞浸润灶2个/4 mm^(2)(淋巴细胞>50个)。头颅磁共振成像可见“蛇眼征”;肌电图显示右侧腓神经运动纤维轴索损伤。在院期间予以大剂量糖皮质激素冲击、联合免疫抑制剂治疗后明显好转。3个月后可推助行器行走,日常生活基本自理。病例2,女性,自81岁起出现颈部不自主右斜,既往有轻度口干、眼干、伴膝关节疼痛1年。实验室检查提示抗SSA/Ro-52抗体、抗SSA/Ro-60抗体阳性,血红蛋白86 g/L;唇腺活检可见小唾液腺组织部分腺泡萎缩,间质内见淋巴细胞、浆细胞浸润灶2个/4 mm^(2)(淋巴细胞>50个)。周围神经电生理检查结果提示右侧正中神经传导速度减慢。经免疫抑制剂、解痉、肌松药物治疗后症状较前好转。结论·以复杂型痉挛性截瘫样表现、颈部肌张力障碍为首发症状的病例拓展了pSS的临床表型谱;临床上应注意鉴别继发于pSS的神经系统损伤与其他原发神经系统疾病;对于具有无明显原因的神经系统损伤症状的患者,应当筛查相关自身免疫抗体。

关键词：原发性干燥综合征神经系统受累痉挛性截瘫痉挛性斜颈

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：