检索结果-南通市图书馆

Radiation Detection technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu cao Jianshe cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH university of science and {2. Faculty of Physics and Applied Computer ScienceKrakow Anhui university HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu university Institute of ScienceVaranasi Bandirma Onyedi Eylul university Bandirma Beihang university Beijing Beijing Computational science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of technology Beijing Beijing Normal university Beijing Brown university ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad university Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo university Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central china Normal university WuhanHubei Central South university ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan china academy of engineering physics MianyangSichuan china building materials academy Beijing china Center of Advanced science and {2. Beijing china Institute of Atomic Energy Beijing china Jiliang university HangzhouZhejiang china Nuclear Instrument CO. LTDBeijing china university of Geo{2.s Beijing china university of Geo{2.s WuhanHubei china university of Mining and {2. XuzhouJiangsu china West Normal university NanchongSichuan Chongqing university Department of PhysicsChongqing Chulalongkorn university Bangkok City university of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell university IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu university DalianLiaoning Dalian university of technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East china university Of {2. And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2.s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,{2.)and the Conceptual Design Report(CDR,{2.),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2.2.-2.2.,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2.30s.

关键词： initiated exceeding precise

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

E2.-1 overexpression inhibits human gastric cancer MGC-803 cell growth in vivo

引用

World Journal of Gastroenterology 2015年第2期21卷 491-501页

作者： Wei-Yuan Wei Lin-Hai Yan Xiao-Tong wang Lei Li Wen-Long cao Xiao-Shi {2. ze-Xu Zhan Han Yu Yu-Bo Xie Qiang Xiao Department of Surgery The First Affiliated Hospital of Guangxi Medical University Department of Surgery People’s Hospital of Guangxi Zhuang Autonomous Region Department of Anaesthesiology The First Affiliated Hospital of Guangxi Medical University

AIM: To evaluate the influence of E2.-1 on the growth of human gastric cancer(GC) cells in vivo and the mechanism involved. METHODS: E2.-1 recombinant lentiviral vectors were injected into xenograft tumors of MGC-803 cells in nude mice, and then tumor growth was investigated. Overexpression of transcription factor E2.-1 was assessed by reverse transcription-polymerase chain reaction(RT-PCR) and Western blotting analysis. Apoptosis rates were determined using a terminal deoxynucleotidyl transferase-mediated d UTP-biotin nick end labeling(TUNEL) assay. Expression levels of certain cell cycle regulators and apoptosis-related proteins, such as Bax, survivin, Bcl-2. cyclin D1, S-phase kinaseassociated protein 2. and c-Myc were examined by Western blotting and RT-PCR. RESULTS: Xenograft tumors of MGC-803 cells in nude mice injected with E2.-1 recombinant lentiviral vectors stably overexpressed the E2.-1 gene as measured by semi-quantitative RT-PCR(relative m RNA expression: 0.10 ± 0.02.vs 0.05 ± 0.02.for control vector and 0.06 ± 0.03 for no infection; both P 1) and Western blotting(relative protein expression: 1.90 ± 0.05 vs 1.10 ± 0.03 in control vector infected and 1.11 ± 0.02.for no infection; both P 1). The growth-curve of tumor volumes revealed that infection with E2.-1 recombinant lentiviral vectors significantly inhibited the growth of human GC xenografts(2.81 ± 1.02.vs 6.18 ± 1.15 in control vector infected and 5.87 ± 1.2. with no infection; both P 15 d after treatment. TUNEL analysis demonstrated that E2.-1 overexpression promoted tumor cell apoptosis(18.6% ± 2.3% vs 6.7% ± 1.2. in control vector infected 6.3% ± 1.2. for no infection; both P 2.-1 overexpression increased theexpression of Bax and suppressed survivin, Bcl-2. cyclin D1, Skp2. and c-Myc expression in tumor ***: E2.-1 inhibits growth of GC cells via regulating multiple signaling pathways, and may play an important ro

关键词： E2.-1 Gastric cancer Lentiviral vector Mouse model

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

mi R-192.5p regulates lipid synthesis in non-alcoholic fatty liver disease through SCD-1

引用

World Journal of Gastroenterology 2017年第46期23卷 8140-8151页

作者： Xiao-Lin Liu Hai-Xia cao Bao-Can wang Feng-Zhi Xin Rui-Nan {2. Da Zhou Rui-Xu Yang ze-Hua Zhao Qin Pan Jian-Gao Fan Center for Fatty Liver Department of GastroenterologyXinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

AIM To evaluate the levels of mi R-192.5 p in non-alcoholic fatty liver disease(NAFLD) models and demonstrate the role of mi R-192.5 p in lipid accumulation. METHODS Thirty Sprague Dawley rats were randomly divided into three groups, which were given a standard diet, a high-fat diet(HFD), and an HFD with injection of liraglutide. At the end of 16 weeks, hepatic mi R-192.5 p and stearoyl-Co A desaturase 1(SCD-1) levels were measured. Mi R-192.5 p mimic and inhibitor and SCD-1 si RNA were transfected into Huh7 cells exposed to palmitic acid(PA). Lipid accumulation was evaluated by oil red O staining and triglyceride assays. Direct interaction was validated by dual-luciferase reporter gene *** The HFD rats showed a 0.46-fold decrease and a 3.5-fold increase in hepatic mi R-192.5 p and SCD-1 protein levels compared with controls, respectively, which could be reversed after disease remission by liraglutide injection(P 1). The Huh7 cells exposed to PA also showed down-regulation and up-regulation of mi R-192.5 p and SCD-1 protein levels, respectively(P 1). Transfection with mi R-192.5 p mimic and inhibitor in Huh7 cells induced dramatic repression and promotion of SCD-1 protein levels, respectively(P 1). Luciferase activity was suppressed and enhanced by mi R-192.5 p mimic and inhibitor, respectively, in wild-type SCD-1(P 1) but not in mutant SCD-1. Mi R-192.5 p overexpression reduced lipid accumulation significantly in PA-treated Huh7 cells, and SCD-1 si RNA transfection abrogated the lipid deposition aggravated by mi R-192.5 p inhibitor(P 1).CONCLUSION This study demonstrates that mi R-192.5 p has a negative regulatory role in lipid synthesis, which is mediated through its direct regulation of SCD-1.

关键词： mi R-192.5p Stearoyl-Co A desaturase 1 High fat diet Lipid synthesis Non-alcoholic fatty liver disease

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Synchrotron Radiation-Based Three-Dimensional Visualization of Angioarchitectural Remodeling in Hippocampus of Epileptic Rats

引用

Neuroscience Bulletin 2020年第4期36卷 333-345页

作者： Pan Gu Zi-Hao Xu Yu-ze cao Sheng-Hui Liao Qian-Fang Deng Xian-Zhen Yin Zhuo-Lu wang Zhuo-Hui Chen Xin-Hang Hu Hui wang Li-Zhi Li Shi-Xin Liu Hul Ding Shu-Peng Shi Hong-Lei Li Ti-Qiao Xiao Bo Xiao Meng-Qi zhang Department of Neurology Xiangya HospitalCentral South UniversityChangsha 410008China School of Information science and Engineering Central South UniversityChangsha 410008China State key laboratory of Drug Research CAS Key Laboratory of Receptor ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Department of Breast Surgery Hunan Provincial Maternal and Child Health Care HospitalChangsha 410008China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201800China

Characterizing the three-dimensional (3D) morphological alterations of microvessels under both normal and seizure conditions is crucial for a better understanding of epilepsy. However, conventional imaging techniques cannot detect microvessels on micron/sub-micron scales without angiography. In this study, synchrotron radiation(SR)-based X-ray in-line phase-contrast imaging (ILPCI)and quantitative 3D characterization were used to acquire high-resolution, high-contrast images of rat brain tissue under both normal and seizure conditions. The number of blood microvessels was markedly increased on days 1 and 14, but decreased on day 60 after seizures. The surface area, diameter distribution, mean tortuosity, and number of bifurcations and network segments also showed similar trends. These pathological changes were confirmed by histological tests. Thus, SR-based ILPCI provides systematic and detailed views of cerebrovascular anatomy at the micron level without using contrast-enhancing agents. This holds considerable promise for better diagnosis and understanding of the pathogenesis and development of epilepsy.

关键词： Epilepsy Synchrotron radiation 3D Angioarchitecture Blood vessel Remodeling

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dehydro-Diels-Alder reaction and diamondization of bowl-shaped clusters C_(18)Te_(3)Br_(4)(Bu-O)_(6)

引用

Nano Research 2022年第5期15卷 4606-4612页

作者： Jinbo zhang Manli Ma Rong Zhou Hongqiang Chu Xue wang Shaojie wang Huhu Tian Zhipeng Yan Mingtao Li Zhongyan Wu Bin Li Jiafeng Yan Lan Anh Thi Nguyen Rongxing cao Guoqing Wu Xianghua zeng Hao-Li zhang Jaeyong Kim Lin wang Yongjun Tian College of Physical science and technology Yangzhou UniversityYangzhou 225002China Center for High Pressure science(CHiPS) State Key Laboratory of Metastable Materials Science and TechnologyYanshan UniversityQinhuangdao 066004China State key laboratory of Applied Organic Chemistry Lanzhou UniversityLanzhou 730000China Baotou Research Institute of Rare Earths Baotou 014000China Academy for Advanced Interdisciplinary Studies Southern University of Science and TechnologyShenzhen 518055China Center for High Pressure science and technology Advanced Research Shanghai 201203China Department of Physics and High Pressure Research CenterHanyang UniversitySeoul 04763Republic of Korea

Dehydro-Diels-Alder(DDA)reaction is a textbook reaction for preparing six-membered rings in solution but is scarcely seen in solid-state *** this work,using multiple characterization techniques,we demonstrate that the bowl-shaped clusters C_(18)Te_(3)Br_(4)(Bu-O)_(6) might experience a DDA reaction at room temperature and high pressure between 5.5 and 7.4 *** 17.0 GPa,it is found that the bonding conversion from the intramolecular sp^(2. to the intermolecular spa occurred,in the form of pressure-induced *** recovered samples from 2..0 and 36.1 GPa showed incomplete reversibility,while the decompression-induced graphitization of glassy carbon was observed during decompression from 46.5 *** electrochemical impedance spectroscopy results indicated that the transport properties changed from grain boundary dominant to grain dominant due to the DDA reaction and the grain boundary effect disappeared as the intermolecular sp3 bonding building-up and carrier transmission channel formation above 17.0 *** results in this study open a new route to construct the crystalline carbon materials with different transport properties.

关键词： polycyclic aromatic hydrocarbons dehydro-Diels-Alder reaction diamondization high-pressure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Value of the peripheral blood B-cells subsets in patients with ankylosing spondylitis

引用

Chinese Medical Journal 2009年第15期122卷 1784-1789页

作者： LIN Qu GU Jie-ruo LI Tian-wang zhang Fu-cheng LIN Zhi-ming LIAO ze-tao WEI Qiu-jing {2. Shuang-yan LI Li Department of Rheumatology Third Affiliated Hospital of Sun Yat-sen University Guangzhou Guangdong 510630 China

Background The role of B-cell remains an enigma in the pathogenesis of ankylosing spondylitis （AS）. This study aimed to investigate the distributions of B-cells and subsets in peripheral blood of AS patients and observe their changes in etanercept-treated AS patents. Methods We detected the proportions of CD19^＋ B-cell, naive B-cell （CD19^＋CD2.）, memory B-cell （CD19^＋CD2.dim） and plasmablast （CD19^＋CD2.high） in peripheral blood of 66 patients with AS （39 at active stage, 2. at stable stage; 35 patients with peripheral joint involvement, 31 patients with axial involvement alone）, 30 patients with rheumatoid arthritis （RA） and 30 healthy volunteers using flow cytometry. And then we observed the changes of the above indexes of 39 active AS patients treated with etanercept in a randomized, double-blind, placebo-controlled trial. Results （1） Percentages of CD19^＋ B-cells in active or peripheral joint involvement AS patients increased more obviously than those in stable or axial involvement alone AS patients （both P=0.001）, and percentage of CD19^＋CD2.high B-cells in AS patients with peripheral joint involvement was significantly higher than that in cases with axial involvement alone or healthy volunteers （P=0.005 and 0.006, respectively）; （2. The percentage of CD19~ B-cells in AS patients was positively correlated with Bath Ankylosing Spondylitis Disease Activity Index （BASDAI） scores, Patient＇s Global Assessment （PGA） scores, total back pain scores and nocturnal back pain scores （r=0.2.0, 0.2.5, 0.2.1.and 0.2.6, P=-0.02., 0.039, 0.042.and 0.031, respectively）; （3） At week 6 and week 12. there were no statistical differences of the percentages of B-cells and subsets between etanercept group and placebo group of AS patients （P 〉0.05）; the percentage of CD19^＋ B-cells in etanercept group was higher than that in healthy volunteers at week 12.（t=3.32., P=0.003）. Conclusions Misbalance is present in B-cells and some subsets in peripheral blood of active AS patients with perip

关键词： spondylitis, ankylosing B-lymphocyte subsets, etanercept

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA

引用

Signal Transduction and Targeted Therapy 2023年第9期8卷 4320-4337页

作者： Zhi-Wei Mo Yue-Ming Peng Yi-Xin zhang Yan Li Bi-Ang Kang Ya-Ting Chen Le Li Mary GSorci-Thomas Yi-Jun Lin Yang cao Si Chen ze-Long Liu Jian-Jun Gao Zhan-Peng Huang Jia-Guo Zhou Mian {2. Guang-Qi Chang Meng-Jie Deng Yu-Jia Liu Zhen-Sheng Ma Zuo-Jun Hu Yu-Gang Dong Zhi-Jun Ou Jing-Song Ou Division of Cardiac Surgery Cardiovascular Diseases InstituteThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina National-Guangdong Joint Engineering laboratory for Diagnosis and Treatment of Vascular Diseases NHC Key Laboratory of Assisted Circulation(Sun Yat-sen University)Guangdong Provincial Engineering and Technology Center for Diagnosis and Treatment of Vascular DiseasesGuangzhouChina Division of Vascular Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Division of Hypertension and Vascular Diseases Department of CardiologyHeart CenterThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Medical College of Wisconsin MilwaukeeWIUSA Center for Translational Medicine Institute of Precision MedicineThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Department of Cardiology Heart CenterThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Department of Pharmacology Cardiac and Cerebral Vascular Research CenterZhongshan School of Medicine of Sun Yat-sen UniversityGuangzhouChina Guangdong Provincial key laboratory of Brain Function and Disease Zhongshan School of MedicineSun Yat-sen UniversityGuangzhou 510080P.R.China

Normal high-density lipoprotein(nHDL)can induce angiogenesis in healthy ***,HDL from patients with coronary artery disease undergoes various modifications,becomes dysfunctional(dHDL),and loses its ability to promote ***,we identified a long non-coding RNA,HDRACA,that is involved in the regulation of angiogenesis by *** this study,we showed that nHDL downregulates the expression of HDRACA in endothelial cells by activating WW domain-containing E3 ubiquitin protein ligase 2.which catalyzes the ubiquitination and subsequent degradation of its transcription factor,Kruppel-like factor 5,via sphingosine 1-phosphate(S1P)receptor *** contrast,dHDL with lower levels of S1P than nHDL were much less effective in decreasing the expression of *** was able to bind to Ras-interacting protein 1(RAIN)to hinder the interaction between RAIN and vigilin,which led to an increase in the binding between the vigilin protein and proliferating cell nuclear antigen(PCNA)mRNA,resulting in a decrease in the expression of PCNA and inhibition of *** expression of human HDRACA in a hindlimb ischemia mouse model inhibited the recovery of *** together,these findings suggest that HDRACA is involved in the HDL regulation of angiogenesis,which nHDL inhibits the expression of HDRACA to induce angiogenesis,and that dHDL is much less effective in inhibiting HDRACA expression,which provides an explanation for the decreased ability of dHDL to stimulate angiogenesis.

关键词： angiogenesis lipoprotein inhibited

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

养殖废水产ESBLs大肠杆菌多重耐药性及耐药基因检测

引用

中国预防兽医学报 2018年第6期40卷 495-499页

作者：李晴张泽曹甸磊常维山王慧王雪鹏山东省动物生物工程与疾病防治重点实验室山东农业大学动物科技学院山东泰安271018 临沂市兰山区畜牧兽医局山东临沂276000

为研究养殖废水中产超广谱β-内酰胺酶(ESBLs)大肠杆菌的分布及其多重耐药性与耐药基因携带情况,本研究对泰安市污水处理厂污水中分离的50株产ESBLs大肠杆菌阳性菌株采用纸片扩散法测定其对19种常见药物的耐药表型。针对产ESBLs菌株的... 详细信息

为研究养殖废水中产超广谱β-内酰胺酶(ESBLs)大肠杆菌的分布及其多重耐药性与耐药基因携带情况,本研究对泰安市污水处理厂污水中分离的50株产ESBLs大肠杆菌阳性菌株采用纸片扩散法测定其对19种常见药物的耐药表型。针对产ESBLs菌株的耐药基因设计6对特异性引物,对ESBLs阳性菌株采用PCR方法检测其耐药基因。结果显示,50株产ESBLs大肠杆菌对β-内酰胺类抗生素表现出较强的耐药性,其中对氨苄西林、头孢噻吩、头孢噻肟呈100%的耐药性;对非β-内酰胺类抗生素同样呈一定耐药性;并且呈多重耐药性。PCR扩增结果显示,分离菌株均含有bla_(TEM)、bla_(CTX-M)基因,有5株含有qrB基因,32.含有qrS基因,有2.不含blaSHV基因,50株菌株均不含qrA基因。本研究表明:养殖场排放的污水已被产ESBL大肠杆菌严重污染,污水是这些耐药基因重要的存储库。且养殖污水中耐药菌通过污水排放最终进入到水环境中,其耐药基因可能在水环境的细菌之间进一步扩散,导致产ESBLs大肠杆菌表现出多重耐药性,同时这些产ESBL大肠杆菌会反过来再次感染动物,造成耐药菌在动物间的传播,甚至造成严重的感染。本研究对水是这些耐药基因重要的存储库这一结论提供了实验佐证。

关键词：超广谱β-内酰胺酶大肠杆菌耐药表型耐药基因多重耐药

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Measurement of the ^(2.2.Th(n,f)cross section in the 1-2.0 MeV range at the CSNS Back-n

引用

Nuclear science and Techniques 2023年第8期34卷 142-153页

作者： Zhi-Zhou Ren Yi-Wei Yang Yong-Hao Chen Rong Liu Bang-Jiao Ye Jie Wen Hai-Rui Guo Zi-Jie Han Qi-Ping Chen Zhong-Wei Wen Wei-Li Sun Han Yi Xing-Yan Liu Tao Ye Jiang-Bo Bai Qi An Jie Bao Yu Bao Ping cao Hao-Lei Chen Zhen Chen zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Xi-Ru Huang Hao-Yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang Bo Li Chao Li Jia-Wen Li Qiang Li Xiao Li Yang Li Jie Liu Shu-Bin Liu ze Long Guang-Yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Jing-Yu Tang Xin-Yi Tang Bin-Bin Tian Li-Jiao wang Peng-Cheng wang Zhao-Hui wang Xiao-Guang Wu Xuan Wu Li-Kun Xie Xiao-Yun Yang Li Yu Tao Yu Yong-Ji Yu Guo-Hui zhang Lin-Hao zhang Qi-Wei zhang Xian-Peng zhang Yu-Liang zhang Zhi-Yong zhang Lu-Ping Zhou Zhi-Hao Zhou Ke-Jun Zhu Department of Modern Physics University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source science Center Dongguan 523803China Institute of Applied Physics and Computational Mathematics Beijing 100088China State key laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230027China key laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China School of Nuclear science and technology University of Science and Technology of ChinaHefei 230027China State key laboratory of Nuclear Physics and {2. School of PhysicsPeking UniversityBeijing 100871China State key laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijingChina Northwest Institute of Nuclear technology Xi’an 710024China university of Chinese Academy of sciences Beijing 100049China Department of Engineering and Applied Physics University of Science and Technology of ChinaHefei 230026China

The ^(2.2.Th(n,f)cross section is very important in basic nuclear physics and applications based on the Th/U fuel *** the time-of-flight method and a multi-cell fast-fission ionization chamber,a novel measurement of the^(2.2.Th(n,f)cross sec-tion relative to^(2.5)U in the 1–2.0 MeV range was performed at the china Spallation Neutron Source Back-n white neutron source(Back-n).The fission event-neutron energy spectra of^(2.2.Th and^(2.5)U fission cells were measured in the single-bunch *** 2.2.h/2.5U fission cross-sectional ratios were obtained,and the measurement uncertainties were 2.5–3.7%for energies in the 2.2. MeV range and 3.6–6.2.for energies in the 2.–2.0 MeV ***^(2.2.Th(n,f)cross section was obtained by introducing the standard cross section of^(2.5)U(n,f).The results were compared with those of previous theoreti-cal calculations,measurements,and *** measured 2.2.h fission cross section agreed with the main evaluation results in terms of the experimental uncertainty,and 2.2.h fission resonances were observed in the 1–3 MeV *** present results provide^(2.2.Th(n,f)cross-sectional data for the evaluation and design of Th/U cycle nuclear systems.

关键词： 2.2.h(n f)cross section Fast-fission ionization chamber Back-n white neutron source

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

国内外低阶煤煤层气储层特征对比研究

引用

煤炭科学技术 2019年第9期47卷 41-50页

作者：王涛邓泽胡海燕曹明亮张宝鑫焦鹏飞余喆长江大学地球科学学院湖北武汉430100 中国石油勘探开发研究院河北廊坊065077 中国石油天然气集团有限公司非常规油气重点实验室河北廊坊065077

中国低阶煤煤层气资源丰富,但勘探和认识程度较低,煤层气成藏条件、煤储层特征和资源潜力等方面研究不足。首先分析了中国低阶煤分布特点和煤层气成因,基于二连盆地、海拉尔盆地、准东地区、吐哈盆地与美国粉河盆地和澳大利亚苏拉特盆... 详细信息

中国低阶煤煤层气资源丰富,但勘探和认识程度较低,煤层气成藏条件、煤储层特征和资源潜力等方面研究不足。首先分析了中国低阶煤分布特点和煤层气成因,基于二连盆地、海拉尔盆地、准东地区、吐哈盆地与美国粉河盆地和澳大利亚苏拉特盆地的煤层气地质资料,探讨了国内外盆地地质构造演化,对比分析了国内外盆地煤阶和煤岩组成、含气量、孔隙度、渗透率和水文地质条件等特征,指出了国内外低阶煤盆地在煤层气含量构成、储层物性条件及水文地质条件等方面的差异,并全方面地阐明了国内外低阶煤盆地含气量差异性的原因。研究结果表明:国内外低阶煤盆地地质构造特征和煤岩特征相似,且煤层气主要是次生生物成因气,国内外低阶煤盆地煤层含气量随埋深总体呈现为先增加后降低的趋势;国内低阶煤盆地与粉河盆地含气量介于0~4m^3/t,但是含气量梯度差异大,埋深相同的条件下,国内低阶煤盆地煤岩含气量低于粉河盆地和苏拉特盆地的含气量。水文地质条件是影响低阶煤煤层气含气量差异的最为重要的因素之一,国内低阶煤盆地水文地质条件差,导致煤层含气量低,粉河盆地和苏拉特盆地水文地质条件好,则含气量高。国内外低阶煤盆地渗透率差异大;国内低阶煤盆地渗透性差,一般小于1.0×10^-3μm^2.粉河盆地和苏拉特盆地渗透性好,要比国内低阶煤盆地高1~2.数量级,导致了国内低阶煤盆地与美国粉河盆地和澳大利亚苏拉特盆地在低阶煤煤储层特征方面的巨大差异。

关键词：煤层气低阶煤储层特征二连盆地粉河盆地

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：