检索结果-南通市图书馆

基于ARIMA-Kalman滤波混合模型的网络负载预测方法

在线全文

学校读者我要写书评

暂无评论

东南大学学报（自然科学版） 2017年第A01期47卷 145-150页

作者：王骞曹菡陕西师范大学计算机科学学院西安710119

由于目前对网络负载预测的研究主要运用单一模型进行预测,忽略了其他因素对网络资源的内在作用,导致数据隐含信息丢失量大、预测结果不准确,故提出一种基于ARIMA-Kalman滤波混合模型预测方法.该方法首先利用ARIMA模型建立一个能反映负... 详细信息

由于目前对网络负载预测的研究主要运用单一模型进行预测,忽略了其他因素对网络资源的内在作用,导致数据隐含信息丢失量大、预测结果不准确,故提出一种基于ARIMA-Kalman滤波混合模型预测方法.该方法首先利用ARIMA模型建立一个能反映负载时间序列数据变化规律的低阶模型,然后将Kalman滤波模型的预测方程与其结合,推导出其状态方程和测量方程,最后利用Kalman滤波的预测迭代方程对工作负载所需资源进行预测.实验结果表明,与单一的时间序列预测方法相比,该方法具有更高的预测精度,有效地提高了资源利用率和虚拟机资源的按需调度效率.

关键词： IPv6 网络负载 ARIMA模型 Kalman滤波资源预测

Neutron Powder Diffraction Study on the Non-Superconducting Phases of ThFeAsN1-xOx（x=0.15,0.6）Iron Pnictide

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2019年第10期36卷 77-80页

作者： Hui-Can Mao Bing-Feng Hu Yuan-Hua Xia Xi-Ping Chen cao Wang Zhi-Cheng Wang Guang-han cao Shi-Liang Li Hui-Qian Luo Department of Physics and Center for Advanced Quantum Studies Beijing Normal UniversityBeijing 100875 Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190 Key Laboratory of Neutron Physics Institute of Nuclear Physics and ChemistryChina Academy of Engineering PhysicsMianyang 621999 Department of Physics Shandong University of TechnologyZibo 255049 Department of Physics and State Key Lab of Silicon Materials Zhejiang UniversityHangzhou 310027 Collaborative Innovation Centre of Advanced Microstructures Nanjing 210093 Songshan Lake Materials Laboratory Dongguan 523808 School of Physical Sciences University of Chinese Academy of SciencesBeijing 100190

We use neutron powder diffraction to study the non-superconducting phases of ThFeAsN1-xOx with x = 0.15,*** our previous results of the superconducting phase ThFeAsN with Tc = 30 K,no magnetic transition is observed by cooling down to 6 K,and possible oxygen occupancy at the nitrogen site is shown in the refinement[***.117(2017)57005].Here in the oxygen doped system ThFeAsN1-xOx,two superconducting regions(0≤x≤0.1 and 0.25≤x≤0.55)are identified by transport experiments[***.:***30(2018)255602].However,within the resolution of our neutron powder diffraction experiment,neither the intermediate doping x= 0.15 nor the heavily overdoped compound x = 0.6 shows any magnetic order from 300 K to 4 ***,while it shares the common phenomenon of two superconducting domes as most 1111-type iron-based superconductors,the magneticall.y ordered parent compound may not exist in this nitride family.

关键词： x=0 compound refinement

T-CELL RESPONSE OF ADVANCED AIDS PATIENTS AFTER HIGHLY ACTIVE ANTIRETROVIRAL THERAPY

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Sciences Journal 2005年第4期20卷 223-225,页

作者： Ai-xia Wang Tai-sheng Li Yun-zhen cao Yang han Zhi-feng Qiu Jing Xie Department of Medicine Infectious Diseases Section Peking Union Medical College Hospital Chiness Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730

Objective To investigate the response on late stage Chinese AIDS patients after highly active antiretroviral therapy （HAART）. Methods From October 2002 to March 2004, 20 cases of late stage Chinese AIDS patients were selected to participate in this opened and randomised study, we purposely chose those with CD4＋ T cell counts 〈 100/mm^3. All of them had one or two opportunistic infections and none had been treated with anti-HIV drugs. All patients were tested with CD4＋（naive CD4＋ T cell defined by CD45RA＋ and CD62L＋, memory CD4＋ T cell defined by CD45RA-）, CD8＋ T cell, plasma HIV viral load, and clinical manifestations on before, during, and after HAART （5 different regimes） on 1, 3, 6, 9, and 12 months. Before HAART mean CD4＋ T cell counts were 32 ± 31 （range 2-91）/mm^3, and plasma HIV viral load were 5.07 ± 0.85（range 2.04-5.70） log copies/mL. In 1 month＇s time patients treated with HAAT had mean CD4＋ and CD8＋ T cell counts increasing rapidly. After 1 month the increasing speed turned to slow down, but HIV viral load decreased predominantly within the first 3 months. The major part of increasing CD4＋ T cells were memory CD4＋ T cells, as for naive CD4＋ T cells increasing low and slow. Clinical symptoms and signs improved, and opportunistic infections reduced. The quality of life will be far much better than before. Each patient was followed for 12 months, and had finished 12 months＇ HAAT. Conclusion This is the first report in China that late stage Chinese AIDS patients after HAART could have their immune reconstitution. The regular pattern is similar to what had been reported in Western countries and also in China. So it is worth to treat late stage Chinese AIDS patients with HAAT.

关键词： acquired immune deficiency syndrome highly active antiretroviral therapy immune reconstitution

Long noncoding RNA Pvt1 promotes the proliferation and migration of Schwann cells by sponging microRNA-214 and targeting c-Jun following peripheral nerve injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第5期18卷 1147-1153页

作者： Bin Pan Di Guo Li Jing Ke Li Xin Li Gen Li Xiao Gao Zhi-Wen Li Wei Zhao Hu Feng Meng-han cao Department of Orthopedics The Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Orthopedics The Second Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Imaging Xuzhou Central HospitalXuzhouJiangsu ProvinceChina College of Extended Education Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Orthopedics Kuitun HospitalYili Kazak Autonomous PrefectureXinjiang Uygur Autonomous RegionChina Center of Clinical Oncology The Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina

Research has shown that long-chain noncoding RNAs(lncRNAs) are involved in the regulation of a variety of biological processes, including peripheral nerve regeneration, in part by acting as competing endogenous RNAs. c-Jun plays a key role in the repair of peripheral nerve injury. However, the precise underlying mechanism of c-Jun remains unclear. In this study, we performed microarray and bioinformatics analysis of mouse crush-injured sciatic nerves and found that the lncRNA Pvt1 was overexpressed in Schwann cells after peripheral nerve injury. Mechanistic studies revealed that Pvt1 increased c-Jun expression through sponging miRNA-214. We overexpressed Pvt1 in Schwann cells cultured in vitro and found that the proliferation and migration of Schwann cells were enhanced, and overexpression of miRNA-214 counteracted the effects of Pvt1 overexpression on Schwann cell proliferation and migration. We conducted in vivo analyses and injected Schwann cells overexpressing Pvt1 into injured sciatic nerves of mice. Schwann cells overexpressing Pvt1 enhanced the regeneration of injured sciatic nerves following peripheral nerve injury and the locomotor function of mice was improved. Our findings reveal the role of lncRNAs in the repair of peripheral nerve injury and highlight lncRNA Pvt1 as a novel potential treatment target for peripheral nerve injury.

关键词： cell migration ceRNA c-Jun lncRNA microarray miR-214 nerve regeneration peripheral nerve injury Pvt1 Schwann cells

Alterations to biological soil crusts with alpine meadow retrogressive succession affect seeds germination of three plant species

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2016年第11期13卷 1995-2005页

作者： LI Yi-kang OUYANG Jing-zheng LIN Li XU Xing-liang ZhanG Fa-wei DU Yan-gong LIU Shu-li cao Guang-min han Fa Key Laboratory of Adaptation and Evolution of Plateau Biota Northwest Institute of Plateau BiologyChinese Academy of SciencesXining 810001China University of Chinese Academy of Sciences Beijing 100049China Institute of Geographic Sciences&Natural Resources Research the Chinese Academy of SciencesBeijing 100101China Liancheng National Nature Reserve of Gansu Province Yongdeng Country 730000China

Biological soil crusts(BSCs) are the important components of alpine meadow *** extent and morphology of BSCs vary greatly with alpine meadow retrogressive succession due to grazing *** is significant interest in impacts of crust composition on plant seed germination,especial l y in(semi-) arid ***,little is known about the influences of BSCs,and their associations with alpine meadow succession,on germination of typical alpine meadow vascular plant *** a full factorial common-gardenexperiment,we studied effects of:(1) crust type,(2) seed position,and(3) surface texture on seed *** chose three typical alpine meadow plant species(*** pratensis,Tibetia himalaica and Potentillen nivea),which belonged to different functional groups(graminoids,legumes,and forbs) and play important roles in all alpine meadow succession *** type and seed position influenced seed germination,and the inhibitory effects of BSCs depended on the crust type and seed species *** major factors influencing seed germination were BSC type,seed position,soil texture,and the interactions between BSC type and seed position; species and seed position; species andsurface texture; and species,crust type,and surface *** crust significantly inhibited germination of all *** position also had a significant effect on seed germination(p han below the surface,this was especially true for *** within cyanobacteria and lichen *** germination rates of *** on the soil surface were significantly correlated with plant occurrence frequency within the alpine meadow *** poor correlation for the other two species is possibly that they are *** results clearly demonstrated that BSCs can be biological filters during seed germination,depending on the BSC succession *** their influences on seed germination,BSCs can strongly

关键词： Crust type Seed position Microenvironment Germination Tibetan Plateau Vascular plants

Clinicopathological features,psychological status,and prognosis of 33 patients with occult breast cancer

在线全文

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2024年第1期14卷 76-87页

作者： Hong-Mei Wang Ao-Yang Yu Lin-Lin Li Lu-Yao Ma Meng-han cao Yu-Le Yang Xiao-Bing Qin Juan-JuanTang Zheng-Xiang han Department of Oncology The Affiliated Hospital of Xuzhou Medical UniversityXuzhou 221000Jiangsu ProvinceChina Graduate School Xuzhou Medical UniversityXuzhou 221004Jiangsu ProvinceChina Department of Pathology The Affiliated Hospital of Xuzhou Medical UniversityXuzhou 221000Jiangsu ProvinceChina

BACKGROUND Occult breast cancer(OBC)has traditionally been considered to be a carcinoma of unknown primary origin with a favorable prognosis and can be treated as stage II-III breast *** to the small number of cases and limited clinical experience,treatments vary greatly around the world and no standardized treatment has yet been *** To investigate the clinicopathological features,psychological status and prognostic features of patients with *** The clinicopathological data of 33 OBC patients diagnosed and treated in the Affiliated Hospital of Xuzhou Medical University and Xuzhou Central Hospital from November 2015 to November 2022 were retrospectively *** psychological status of OBC patients was evaluated by the Self-rating Anxiety Scale and Self-rating Depression ***’emotions,stress perception and psychological resilience were evaluated by the Positive and Negative Affect Schedule,the Chinese Perceived Stress Scale,and the Connor-Davidson Resilience Scale(CD-RISC),*** survival was calculated using the Kaplan-Meier method,and survival curves were plotted for analysis with the log-rank *** and multivariate survival analyses were performed using the Cox regression *** The 33 OBC patients included 32 females and 1 *** the 33 patients,30(91%)had axillary tumors,3(9%)had a neck mass as the primary symptom;18(54.5%)had estrogen receptor-positive tumors,17(51.5%)had progesterone receptor-positive tumors,and 18(54.5%)had Her-2-positive tumors;24(72.7%)received surgical treatment,including 18 patients who underwent modified radical mastectomy,1 patient who underwent breast-conserving surgery plus axillary lymph node dissection(ALND),and 5 patients who underwent ALND alone;12 patients received preoperative neoadjuvant *** 30 patients developed anxiety and depression,with low positive affect scores and high negative affect scores,accompanied by a high stress level and poor psycho

关键词： Occult breast cancer Breast cancer Perceived Stress Scale Axillary lymph node dissection

Combined effect of microplastic and triphenyltin:Insights from the gut-brain axis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Environmental Science and Ecotechnology 2023年第4期16卷 156-167页

作者： Si-Qi Zhang Ping Li Shu-Wen He Shao-Ying Xing Zhi-han cao Xue-Li Zhao Cuici Sun Zhi-Hua Li Marine College Shandong UniversityWeihaiShandong264209China State Key Laboratory of Tropical Oceanography South China Sea Institute of OceanologyChinese Academy of Sciences510301GuangzhouChina

Microplastics(MPs),an emerging group of pollutants,not only have direct toxic effects on aquatic organisms but also cause combined toxicity by absorbing other ***(TPT),one of the most widely used organotin compounds,has adverse effects on aquatic ***,little is known about the combined toxicity of MPs and TPT to aquatic *** investigate the individual and combined toxicity of MPs and TPT,we selected the common carp(Cyprinus carpio)for a 42-day exposure *** on the environmental concentrations in a heavily polluted area,the experimental concentrations of MPs and TPT were set at 0.5 mg L^(−1) and 1μg L^(−1),*** effects of MPs combined with TPT on the carp gut-brain axis were evaluated by detecting gut physiology and biochemical parameters,gut microbial 16S rRNA,and brain transcriptome *** results suggest that a single TPT caused lipid metabolism disorder and a single MP induced immunosuppression in *** MPs were combined with TPT,the involvement of TPT amplified the immunotoxic effect induced by *** this study,we also explored the gut-brain axis relationship of carp immunosuppression,providing new insights for assessing the combined toxicity of MPs and *** the same time,our study provides a theoretical basis for evaluating the coexistence risk of MPs and TPT in the aquatic environment.

关键词： Aquatic organism Combined toxicity Ecological risk Environmental concentration

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

乡村振兴与中国人类学研究的新议题

广西民族大学学报（哲学社会科学版） 2019年第5期41卷 18-26页

作者：曹晗广西民族大学民族学与社会学学院广西南宁 530006

乡村是孕育中国人类学成长的土壤,乡村社会发展变迁历来都为人类学独特且重要的研究领域。时下,乡村振兴的浪潮给乡村带来前所未有的发展机遇和挑战,因之人类学应对乡村的价值与功能、产业与城乡双融合发展、农民组织化与乡村治理体系... 详细信息

乡村是孕育中国人类学成长的土壤,乡村社会发展变迁历来都为人类学独特且重要的研究领域。时下,乡村振兴的浪潮给乡村带来前所未有的发展机遇和挑战,因之人类学应对乡村的价值与功能、产业与城乡双融合发展、农民组织化与乡村治理体系现代化建设、乡村生态文明建设与人居生活环境改善以及乡村传统文化资源传承与创新等相关议题进行全面而深入的研究,既要做扎实的田野调查,更要从中提炼出适用于中国社会发展的理论与概念,并在实践上为乡村振兴做出学科贡献。

关键词：乡村振兴乡村人类学乡村传统文化资源

Apoptotic B16-F1 Cells Coated with Recombinant Calreticulin Mediated Anti-tumor Immune Response in Mice

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Cancer Research 2010年第4期22卷 253-259页

作者： Chun-yu cao Yu han Yu-shan Ren Yan-lin Wang Three Gorges University Medical College Three Gorges University Institute of Molecular Biology Yichang 443002 China

Objective： To investigate the recombinant calreticulin （rCRT） mediated antitumor immune response. Methods： Cell proliferation was determined by MTT method, apoptosis was evaluated by DNA fragmentation and CRT expression and cell localization were assayed by western blotting, QT-RT-PCR and immunofluorescence assays. The mouse melanoma cell line B16-F1 was treated with polyamine analogue BENS to induce apoptosis and incubated with rCRT to get rCRT coated on the membrane, and then the cells were used to immune BALB/c mice as a cell-antigen. Immunized animals were rechallenged by live B16-F1 cells and then tumor generation ratio and the lactate dehydrogenase release assay were used to evaluate antitumor effects of rCRT-mediated immunity. Results： BENS induced apoptosis of B16-F1 cells without the redistribution of CRT within the cells. When B16-F1 cells coated with rCRT were used as cell-antigen to inoculate the animals, the mice obtained the ability in inhibiting proliferation of homologous tumor cells in vivo. Comparing with the positive control group, the splenocytes from those inoculated mice have an obvious enhancement on their cytolytic effects specifically against B16-F1 cells. Conclusion： rCRT coated on the cell surface can enhance immunogenicity of apoptotic tumor cells and mediated effective anti-tumor immunoresponse in mice.

关键词： Calreticulin Tumor immunity Melanoma Mouse