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The Role of BMOA in the Boundedness of Weighted Composition Operators on the Unit Ball

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Acta Mathematica Sinica,English Series 2014年第2期30卷 323-330页

作者： Chao ZHANG Guang fu cao College of Mathematics and Information Sciences Guangzhou University

We study the weighted composition operators Wh,on Hardy space H2（B） whenever h ∈ BMOA（resp.h ∈ VMOA）.Analogous results are given for Hp（B） spaces and the scale of weighted Bergman *** the latter case,BMOA is... 详细信息

关键词： Weighted composition operator boundedness compactness BMOA VMOA

Biomimetic nanomedicines for precise atherosclerosis theranostics

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Acta Pharmaceutica Sinica B 2023年第11期13卷 4442-4460页

作者： Ying Tao Xinmiao Lan yang Zhang Chenxing fu Lu Liu Feng cao Weisheng Guo Department of Minimally Invasive Interventional Radiology Key Laboratory of Molecular Target&Clinical PharmacologySchool of Biomedical Engineering&the Second Affiliated HospitalGuangzhou Medical UniversityGuangzhou 510260China School of Pharmaceutical Sciences Capital Medical UniversityBeijing 100069China Department of Cardiology the Second Medical Center&National Clinical Research Center for Geriatric DiseasesChinese PLA General HospitalBeijing 100853China Department of Cardiology and Laboratory of Heart Center Zhujiang HospitalSouthern Medical UniversityGuangzhou 510280China Department of Pharmacology and Pharmacy Li Ka Shing Faculty of Medicinethe University of Hong KongHong Kong SAR 999077China

Atherosclerosis(AS)is a leading cause of the life-threatening cardiovascular disease(CVD),creating an urgent need for efficient,biocompatible therapeutics for diagnosis and *** nanomedicines(b NMs)are moving closer to fulfilling this need,pushing back the frontier of nano-based drug delivery systems *** review seeks to outline how these nanomedicines(NMs)might work to diagnose and treat atherosclerosis,to trace the trajectory of their development to date and in the coming years,and to provide a foundation for further discussion about atherosclerotic theranostics.

关键词： Nanotheranostics Atherosclerosis Biomimetic nanomedicines Drug delivery Passive targeting Active targeting Plaques Diagnosis and treatment

“材料成形设备与控制”课程改革——面向新工科建设与通识教育的教学改革探索

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教育教学论坛 2022年第30期 67-70页

作者：王小松王东君曹福洋王克环刘钢哈尔滨工业大学材料科学与工程学院黑龙江哈尔滨150001

材料成形设备是实现材料成形工艺的载体,现有授课内容主要讲授常见材料成形设备结构与机械传动原理,滞后于市场和产业发展需求,难以满足新工科建设培养多元化、创新型卓越工程人才的要求。因此提出面向新工科建设的“材料成形设备与控... 详细信息

材料成形设备是实现材料成形工艺的载体,现有授课内容主要讲授常见材料成形设备结构与机械传动原理,滞后于市场和产业发展需求,难以满足新工科建设培养多元化、创新型卓越工程人才的要求。因此提出面向新工科建设的“材料成形设备与控制”课程建设方案,以材料成形设备的主要核心控制元素(力和位移)精确控制为主线,重点讲述计算机控制、伺服控制方法与材料成形设备传统机械结构、液压传动的结合应用,并进行了智能成形设备的展望,既保证了课程核心要点的教学,又拓宽了学生的知识面,提高了学生的创新能力,取得了较好的教学效果。

关键词：材料成形设备与控制新工科建设通识教育计算机控制伺服控制

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Expression profile of long non-coding RNAs in the intestine of black rockfish Sebastes schlegelii in response to Edwardsiella tarda infection

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Journal of Oceanology and Limnology 2023年第1期41卷 376-391页

作者： Xu YAN Min cao Qiang fu Ning yang Ningning WANG Lin SONG Chao LI College of Chemistry and Molecular Engineering Qingdao University of Science and TechnologyQingdao 266011China School of Marine Science and Engineering Qingdao Agricultural UniversityQingdao 266109China

Long non-coding RNAs(lncRNAs)are a class of transcripts longer than 200 bp,which have been emerged as essential regulators in numerous biological *** rockfish(Sebastes schlegelii)is an economic fish that widely cultured in the coastal areas of China,Japan,and South *** the expansion of aquacultural scale,various pathogens have threatened its industry and reduced its economic *** has been reported that lncRNA were involved in the immune response and metabolic pathway in teleost,while no study is available on identification and functional analysis of lncRNAs in black rockfish so ***,this study was performed to identify lncRNAs in the intestine of black rockfish after Edwardsiella tarda *** our results,a total of 9311 lncRNAs were identified through highthroughput sequencing,and 102 lncRNAs were significantly regulated following challenge,which were predicted to target 3348 *** of Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)enrichment analyses of the se target genes showed they were function in catalytic activity,hydrolase activity,defense response and peptidase activity,which involved in metabolic pathways and immune related *** addition,47 lncRNAs and 8 differentially expressed mRNAs(DEmRNAs)showed co-expression at two or more infection time points with metabolism and immunity ***,real-time quantitative PCR(qRT-PCR)was performed to verify the reliability of sequencing gene expression analysis *** research laid the foundation for further investigation of the regulatory roles of lncRNAs in the intestinal immune response of black rockfish.

关键词： long non-coding RNA mRNA intestine Sebastes schlegelii Edwardsiella tarda

An investigation on stress distribution effect on multi- piezoelectric energy harvesters

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Frontiers of Structural and Civil Engineering 2017年第3期11卷 301-307页

作者： Hailu yang Dongwei cao National Center for Materials Service Safety University of Science and Technology Beijing Beijing China Research of Institute of Highway Ministry of Transport Beijing China

With the fast development of piezoelectric materials and due to its green and renewable characteristics, the piezoelectric energy harvesting technology has been paid more and more attention by pavement engineers. The stress distribution will significantly affect the piezoelectric material performance. In this paper, the effects of multiple piezoelectric elements on the generation of electrical energy and output power are studied. In the case of constant external load, the number of the piezoelectric units does not necessarily produce more energy. When the same multi piezoelectric units work together, if the stress state of the piezoelectric units is different, the total output energy affected by the connection mode. For uneven stress distribution, the optimal output mode is that each of the piezoelectric units rectified before connected in parallel.

关键词： piezoelectric transdUcer uneven stress impedance matching optimal energy output

A New High-Efficiency Experimental Design for Optimizing Various Flow Velocities Testing in Extremely Aggressive Formation Water

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Acta Metallurgica Sinica(English Letters) 2019年第8期32卷 944-950页

作者： yang Zhao Shu-Yun cao Tao Zhang Jun-Feng Xie Da-Ke Xu fu-Hui Wang Shenyang National Laboratory for Materials Science Northeastern University3-11 Wenhua RoadShenyang 110819China State Key Laboratory of Separation Membranes and Membrane Processes School of Material Science and EngineeringTianjin Polytechnic UniversityTianjin 300387China Petrochina Tarim Oilfield Company Shihua RoadKorla 841000China

Compared to the traditional one-by-one method,a new high-efficiency method is used to characterize large numbers of regulations varying ***,bump-shaped electrodes are designed using the computational fluid dynamics model,and the effect of the height and placement of these electrodes is *** experimental feasibility is certified by weight loss *** indicate that flow velocities of different bump-shaped electrode surfaces are significant ***,each surface can be analyzed independently;the thickness loss of each electrode surface is consistent with that using one-by-one method,which can effectively improve the experimental efficiency 12 times.

关键词： Bump-shaped electrodes High efficiency Computational fluid dynamics(CFD) Weight loss

Comparative histology,transcriptome,and metabolite profi ling unravel the browning mechanisms of calli derived from ginkgo(Ginkgo biloba L.)

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Journal of Forestry Research 2023年第3期34卷 677-691页

作者： Xiaoming yang Qi Xu Linlin Le Tingting Zhou Wanwen Yu Guibin Wang Fang-Fang fu fuliang cao Co-Innovation Center for Sustainable Forestry in Southern China Nanjing Forestry UniversityNanjing 210037People’s Republic of China

Gingko biloba accumulates high levels of secondary metabolites of pharmaceutical *** calli develop a typical browning that reduces its regenerative capacity and thus its *** elucidate the browning mechanism,histological,transcriptomic,and metabolic alterations were compared between green and browning calli derived from immature ginkgo *** observations revealed that browning calli had a more loosely arranged cell structure and accumulated more tannins than in green *** metabolic and transcriptomic analyses showed that phenylpropanoid metabolism was specifi-cally activated in the browning calli,and 428 diff erentially expressed genes and 63 diff erentially abundant metabolites,including 12 fl avonoid compounds,were identifi ed in the browning calli compared to the green ***,the expression of fl avonol synthase(FLS)and UDP-glucuronosyl-transferase(UGT)genes involved in the fl avonoid pathway was more than tenfold higher in browning calli than in green calli,thus promoting biosynthesis of fl avonol,which serves as a substrate to form glycosylated fl *** glycosides constituted the major coloring component of the browning calli and may act in response to multiple stress conditions to delay cell death caused by *** results revealed the cellular and biochemical changes in browning callus cells that accompanied changes in expression of browning-related genes,providing a scientifi c basis for improving ginkgo tissue culturability.

关键词： Ginkgo Callus browning Histology Transcriptome Metabolite Flavonoid biosynthesis

Establishment of human cerebral organoid systems to model early neural development and assess the central neurotoxicity of environmental toxins

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Neural Regeneration Research 2025年第1期20卷 242-252页

作者： Daiyu Hu Yuanqing cao Chenglin Cai Guangming Wang Min Zhou Luying Peng Yantao Fan Qiong Lai Zhengliang Gao fundamental Research Center Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center)School of MedicineTongji UniversityShanghaiChina Institute of Geriatrics(Shanghai University) Affiliated Nantong Hospital of Shanghai University(The Sixth People’s Hospital of Nantong)Shanghai University School of MedicineNantongJiangsu ProvinceChina Shanghai Engineering Research Center of Organ Repair Shanghai University School of MedicineShanghaiChina Key Laboratory of Arrhythmias Ministry of EducationShanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina

Human brain development is a complex process,and animal models often have significant *** address this,researchers have developed pluripotent stem cell-derived three-dimensional structures,known as brain-like organoids,to more accurately model early human brain development and *** enable more consistent and intuitive reproduction of early brain development,in this study,we incorporated forebrain organoid culture technology into the traditional unguided method of brain organoid *** involved embedding organoids in matrigel for only 7 days during the rapid expansion phase of the neural epithelium and then removing them from the matrigel for further cultivation,resulting in a new type of human brain organoid *** cerebral organoid system replicated the temporospatial characteristics of early human brain development,including neuroepithelium derivation,neural progenitor cell production and maintenance,neuron differentiation and migration,and cortical layer patterning and formation,providing more consistent and reproducible organoids for developmental modeling and toxicology *** a proof of concept,we applied the heavy metal cadmium to this newly improved organoid system to test whether it could be used to evaluate the neurotoxicity of environmental *** organoids exposed to cadmium for 7 or 14 days manifested severe damage and abnormalities in their neurodevelopmental patterns,including bursts of cortical cell death and premature *** exposure caused progressive depletion of neural progenitor cells and loss of organoid integrity,accompanied by compensatory cell proliferation at ectopic *** convenience,flexibility,and controllability of this newly developed organoid platform make it a powerful and affordable alternative to animal models for use in neurodevelopmental,neurological,and neurotoxicological studies.

关键词： cadmium cell death cell proliferation cortical development environmental toxins neural progenitor cells neurogenesis neurotoxicology organoids stem cells

Advanced Design of Soft Robots with Artificial Intelligence

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Nano-Micro Letters 2024年第10期16卷 474-521页

作者： Ying cao Bingang Xu Bin Li Hong fu Nanotechnology Center School of Fashion and TextilesThe Hong Kong Polytechnic UniversityHong Kong 999077People's Republic of China Department of Mathematics and Information Technology The Education University of Hong KongHong Kong 999077People's Republic of China Bioinspired Engineering and Biomechanics Center Xi'an Jiaotong UniversityXi'an 710049People's Republic of China

In recent years,breakthrough has been made in the field of artificial intelligence(AI),which has also revolutionized the industry of *** robots featured with high-level safety,less weight,lower power consumption have always been one of the research ***,multifunctional sensors for perception of soft robotics have been rapidly developed,while more algorithms and models of machine learning with high accuracy have been optimized and *** of soft robots with AI have also been advanced ranging from multimodal sensing,human-machine interaction to effective actuation in robotic ***-less,comprehensive reviews concerning the new developments and strategies for the ingenious design of the soft robotic systems equipped with AI are ***,the new development is systematically reviewed in the field of soft robots with ***,background and mechanisms of soft robotic systems are briefed,after which development focused on how to endow the soft robots with AI,including the aspects of feeling,thought and reaction,is ***,applications of soft robots with AI are systematically summarized and discussed together with advanced strategies proposed for performance *** thoughts for future intelligent soft robotics are pointed ***,some perspectives are put forward.

关键词： Soft robotic systems Artificial intelligence Design tactics Review and perspective