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Influence of the Nongyrotropy on the Gyrotropic Ring Instability

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Chinese Physics Letters 1998年第1期15卷 38-40页

作者： CAO Jin-bin WANG Xue-yi cai chun-lin Center for Space Science and Applied Research Chinese Academy of ScienceBeijing 100080

The instability driven by the nongyrotropic newborn ions is studied for oblique *** results show the influence of nongyrotropic on the gyrotropic ring instability decreases when the propagation angle *** growth rate in the case of nongyrotropic is smaller than that in the case of *** nongyrotropic also breaks the symmetry of the propagation of the waves in the plane perpendicular to the ambient magnetic field.

关键词： field symmetry ambient

Difference Between the Ion Gyroviscous Effect and Hall Magnetohydrodynamic Effect in the Magnetic Reconnection

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Chinese Physics Letters 1999年第11期16卷 856-858页

作者： cai chun-lin ZHOU Guo-cheng CAO Jin-bin WANG De-ju Center for Space Science and Applied Research Chinese Academy of SciencesBeijing 100080

We study the ion gyroviscous effect and Hall magnetohydrodynamic (MHD) effect separately using the modified MHD simulation of the magnetopause. Simulations show that the ion gyroviscous effect is on the order of a characteristic scale of ion Larmor radius and is mainly limited near the magnetosheath boundary. The Hall MHD effect is on the order of a characteristic scale of ion inertial length and occurs mainly in the central region of the current layer. The magnetic field component out of the simulation plane has a bipolar structure near the magnetosheath boundary from the ion gyroviscous effect and a quadrupole structure in the central region of the current layer from the Hall MHD effect. These results are of fundamental importance in understanding the reconnection processes in space and astrophysical plasma.

关键词： viscous effect effect.

Assembly of highly efficient aqueous light-harvesting system from sequence-defined peptoids for cytosolic microRNA detection

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Nano Research 2024年第2期17卷 788-796页

作者： Yang Song Xiaoli cai Mingming Wang Dan Du Yuehe lin chun-Long Chen Department of Mechanical and Materials Engineering Washington State UniversityPullmanWA 99164USA Division of Physical Sciences Pacific Northwest National LaboratoryRichlandWA 99352USA Department of Chemical Engineering University of WashingtonSeattleWA 98195USA

Precisely controlled spatial distributions of artificial light-harvesting systems in aqueous media are of significant importance for mimicking natural light-harvesting systems;however,they are often restrained by the solubility and the aggregation-caused quenching effect of the hydrophobic ***,we report one highly efficient artificial light-harvesting system based on peptoid nanotubes that mimic the hierarchical cylindrical structure of natural *** high crystallinity of these nanotubes enabled the organization of arrays of donor chromophores with precisely controlled spatial distributions,favoring an efficient Förster resonance energy transfer(FRET)process in aqueous *** FRET system exhibits an extremely high efficiency of 98.6%with a fluorescence quantum yield of 40%and an antenna effect of *** further demonstrated the use of this artificial light-harvesting system for quantifying miR-210 within cancer *** fluorescence intensity ratio of donor to acceptor is linearly related to the concentration of intercellular miR-210 in the range of 3.3–156 copies/*** high sensitivity in intracellular detection of miR-210 using this artificial light-harvesting system offers a great opportunity and pathways for biological imaging and detection,and for the further creation of microRNA(miRNA)toolbox for quantitative epigenetics and personalized medicine.

关键词： light-harvesting peptoid nanotube Förster resonance energy transfer intracellular RNA detection

Modified Magnetohydrodynamic Model of Magnetic Reconnection

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Chinese Physics Letters 1999年第6期16卷 461-463页

作者： ZHOU Guo-cheng cai chun-lin CAO Jin-bin ZHANG Yang-ting CHEN Tao WANG De-ju Center for Space Science and Applied Research Chinese Academy of SciencesBeijing 100080

This paper presents the modified magnetohydrodynamic(MHD)model and simulations of solar wind-magnetosphere *** use the two-dimensional and three-component,compressible,resistive,ion gyroviscous and Hall MHD model,i.e.,including the ion Unite Larmor radius(FLR)and Hall MHD effects,but neglecting the electron inertia and electron FLR *** composed dynamic pressure pulses(shear variations in the How velocity)in the solar wind form gusts that continually buffet the magnetosphere and cause the time-dependent magnetic reconnection at the *** results show that the magnetic Held and the How velocity components perpendicular to the reconnection plane can be generated in magnetopause current *** vortical How structures can also occur in the magnetospheric side *** results are responsible for non-ideal MHD properties of the plasma fluid,i.e.,ion FLR and Hall MHD effects.

关键词： reconnection effects. inertia

Prediction of contact resistance of electrical contact wear using different machine learning algorithms

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Friction 2024年第6期12卷 1250-1271页

作者： Zhen-bing cai chun-lin LI Lei YOU Xu-dong CHEN Li-ping HE Zhong-qing CAO Zhi-nan ZHANG Tribology Research Institute Southwest Jiaotong UniversityChengdu 610031China State Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong UniversityShanghai 200240China

H62 brass material is one of the important materials in the process of electrical energy transmission and signal transmission,and has excellent performance in all *** the wear behavior of electrical contact pairs is particularly complex when they are in service,we evaluated the effects of load,sliding velocity,displacement amplitude,current intensity,and surface roughness on the changes in contact *** learning(ML)algorithms were used to predict the electrical contact performance of different factors after wear to determine the correlation between different factors and contact *** forest(RF),support vector regression(SVR)and BP neural network(BPNN)algorithms were used to establish RF,SVR and BPNN models,respectively,and the experimental data were trained and *** was proved that BP neural network model could better predict the stable mean resistance of H62 brass alloy after *** analysis shows that the load and current have great influence on the predicted electrical contact *** wear behavior of electrical contacts is influenced by factors such as load,sliding speed,displacement amplitude,current intensity,and surface roughness during *** learning algorithms can predict the electrical contact performance after wear caused by these *** results indicate that an increase in load,current,and surface roughness leads to a decrease in stable mean resistance,while an increase in displacement amplitude and frequency results in an increase in stable mean resistance,leading to a decline in electrical contact *** reduce testing time and costs and quickly obtain the electrical contact performance of H62 brass alloy after wear caused by different factors,three algorithms(random forest(RF),support vector regression(SVR),and BP neural network(BPNN))were used to train and test experimental results,resulting in a machine learning model suitable for predicting the stable mean

关键词： electrical contact wear contact resistance machine learning(ML) neural network

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伴随着高速流的磁尾电流片拍动观测研究

地球物理学报 2015年第10期58卷 3449-3456页

作者：魏新华蔡春林中国科学院空间科学与应用研究中心空间天气国家重点实验室北京100190

磁尾电流片在磁尾动力学过程中起着重要作用.卫星观测表明磁尾电流片经常处于拍动状态.但磁尾电流片拍动的特性和产生机制至今仍然没有被完全弄清楚.本文主要利用欧洲空间局Cluster卫星数据,研究一个伴随高速离子流的电流片拍动事件.该... 详细信息

磁尾电流片在磁尾动力学过程中起着重要作用.卫星观测表明磁尾电流片经常处于拍动状态.但磁尾电流片拍动的特性和产生机制至今仍然没有被完全弄清楚.本文主要利用欧洲空间局Cluster卫星数据,研究一个伴随高速离子流的电流片拍动事件.该电流片拍动事件具有很强的周期性.拍动的周期约是2min,磁场振荡幅度约为20nT.能量电子和离子的通量具有周期性增强和减弱的特征.电流密度X和Y分量也具有周期性的振荡,并且振荡周期与磁场振荡周期一致.通过对粒子流速矢量与电流矢量的分析,发现粒子运动具有涡旋的特征.因此可以推断,该磁尾电流片的拍动不是由磁尾等离子体片高速流产生的,而是与局地等离子体不稳定性有关.

关键词：电流片拍动高速流能量离子电流

Ubiquitin-specific protease 21 promotes tumorigenicity and stemness of colorectal cancer by deubiquitinating and stabilizing ZEB1

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 1006-1018页

作者： Jun-Jun lin Ye-cai Lu Department of Gastrointestinal Surgery Chaohu Hospital of Anhui Medical UniversityChaohu 238000Anhui ProvinceChina

BACKGROUND Colorectal cancer(CRC)is one very usual tumor together with higher death ***-specific protease 21(USP21)has been confirmed to take part into the regulation of CRC progression through serving as a ***,the promotive function of USP21 has also discovered in the progression of ***1 has illustrated to be modulated by USP7,USP22 and USP51 in ***,the regulatory functions of USP21 on ZEB1 in CRC progression need more *** To investigate the relationship between USP21 and ZEB1 in CRC *** The mRNA and protein expressions were assessed through RT-qPCR,western blot and IHC *** interaction between USP21 and ZEB1 was evaluated through Co-IP and GST pull down *** cell proliferation was detected through colony formation *** cell migration and invasion abilities were determined through Transwell *** stemness was tested through sphere formation *** tumor growth was evaluated through in vivo mice *** In this work,USP21 and ZEB1 exhibited higher expression in CRC,and resulted into poor ***,the interaction between USP21 and ZEB1 was further *** was demonstrated that USP21 contributed to the stability of ZEB1 through modulating ubiquitination *** addition,USP21 streng-thened cell proliferation,migration and stemness through regulating *** last,through in vivo assays,it was illustrated that USP21/ZEB1 axis aggravated tumor *** For the first time,these above findings manifested that USP21 promoted tumorigenicity and stemness of CRC by deubiquitinating and stabilizing *** discovery suggested that USP21/ZEB1 axis may provide novel sights for the treatment of CRC.

关键词： Ubiquitin-specific protease 21 ZEB1 Stemness Colorectal cancer

Solving Multi-Objective Vehicle Routing Problems with Time Windows: A Decomposition-Based Multiform Optimization Approach

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Tsinghua Science and Technology 2024年第2期29卷 305-324页

作者： Yiqiao cai Zifan lin Meiqin Cheng Peizhong Liu Ying Zhou Xiamen Key Laboratory of Data Security and Blockchain Technology College of Computer Science and TechnologyHuaqiao UniversityXiamen361021China College of Engineering Huaqiao UniversityQuanzhou362000China School of Computer Sciences Shenzhen Institute of Information TechnologyShenzhen518000China

In solving multi-objective vehicle routing problems with time windows (MOVRPTW),most existing algorithms focus on the optimization of a single problem formulation. However,little effort has been devoted to exploiting valuable knowledge from the alternate formulations of MOVRPTW for better optimization performance. Aiming at this insufficiency,this study proposes a decomposition-based multi-objective multiform evolutionary algorithm (MMFEA/D),which performs the evolutionary search on multiple alternate formulations of MOVRPTW simultaneously to complement each other. In particular,the main characteristics of MMFEA/D are three folds. First,a multiform construction (MFC) strategy is adopted to construct multiple alternate formulations,each of which is formulated by grouping several adjacent subproblems based on the decomposition of MOVRPTW. Second,a transfer reproduction (TFR) mechanism is designed to generate offspring for each formulation via transferring promising solutions from other formulations,making that the useful traits captured from different formulations can be shared and leveraged to guide the evolutionary search. Third,an adaptive local search (ALS) strategy is developed to invest search effort on different alternate formulations as per their usefulness for MOVRPTW,thus facilitating the efficient allocation of computational resources. Experimental studies have demonstrated the superior performance of MMFEA/D on the classical Solomon instances and the real-world instances.

关键词： MOVRPTW multiform optimization multiform construction knowledge transfer adaptive local search

Clinical analysis of secondary penile cancer:a case series at a tertiary referral center in China

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Asian Journal of Andrology 2024年第2期26卷 225-226页

作者： Xiao-Yu Li chun-Ru Xu Xing Ji Zhen-Peng Zhu Zhen-Ke Guo Tian-Yu cai Jian lin Department of Urology Peking University First HospitalBeijing 100034China Institute of Urology Peking UniversityBeijing 100034China National Urological Cancer Center Beijing 100034China Beijing Key Laboratory of Urogenital Diseases(Male)Molecular Diagnosis and Treatment Center Beijing 100034China

Dear Editor,Secondary penile cancer is an extremely rare condition that refers to the metastasis of other malignancies to the *** are limited reports on secondary penile cancer in Asian populations,and perceptions about this disease are extremely *** reviewed and analyzed the data of patients diagnosed with secondary penile cancer based on the pathological findings at Peking University First Hospital in Beijing,China,aiming to expand the clinical reference for this rare disease.

关键词： cancer rare finding