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Soluble ST2:A novel Biomarker for Diagnosis and Prognosis of cardiovascular Disease

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当代医学科学（英文） 2024年第4期44卷 669-679页

作者： Yin FEnG Li-qun he Department of cardiology Traditional Chinese and Western Medicine Hospital of WuhanTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

The increasing incidence of cardiovascular disease(cVD)is a significant global health concern,affecting millions of individuals each *** diagnosis of acute cVD poses a formidable challenge,as misdiagnosis can significantly decrease patient survival *** biomarkers have played a vital role in the diagnosis and prognosis of cVDs,but they can be influenced by various factors,such as age,sex,and renal *** ST2(sST2)is a novel biomarker that is closely associated with different *** low reference change value makes it suitable for continuous measurement,unaffected by age,kidney function,and other confounding factors,facilitating risk stratification of ***,the combination of sST2 with other biomarkers can enhance diagnostic accuracy and prognostic *** review aims to provide a comprehensive overview of sST2,focusing on its diagnostic and prognostic value as a myocardial marker for different types of cVDs and discussing the current limitations of sST2.

关键词： cardiovascular disease combined biomarker diagnosis and prognosis limitations soluble ST2

construction of core@double-shell structured energetic composites with simultaneously enhanced thermal stability and safety performance

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Defence Technology（防务技术） 2024年第4期34卷 134-142页

作者： Peng Wang Wen Qian Ruolei Zhong Fangfang he Xin Li Jie chen Li Meng Yinshuang Sun Guansong he Institute of chemical Materials China Academy of Engineering PhysicsMianyang 621900China State Key Laboratory of Environment-friendly Energy Materials School of Materials and ChemistrySouthwest University of Science and TechnologyMianyang 621010China

The poor thermal stability and high sensitivity severely hinder the practical application of hexanitrohexaazaisowurtzitane(cL-20).herein,a kind of novel core@double-shell cL-20 based energetic composites were fabricated to address the above *** coordination complexes which consist of natural polyphenol tannic acid(TA) and Fe~Ⅲ were chosen to construct the inner shell,while the graphene sheets were used to build the outer *** resulting cL-20/TA-Fe~Ⅲ/graphene composites exhibited simultaneously improved thermal stability and safety performance with only 1 wt% double-shell content,which should be ascribed to the intense physical encapsulation effect from inner shell combined with the desensitization effect of carbon nano-materials from outer *** phase transition(ε to γ) temperature increased from 173.70 ℃ of pure cL-20 to 191.87℃ of cL-20/TA-Fe~Ⅲ/graphene ***,the characteristic drop height(H_(50)) dramatically increased from 14.7 cm of pure cL-20 to112.8 cm of cL-20/TA-Fe~Ⅲ/graphene composites,indicating much superior safety performance after the construction of the double-shell *** general,this work has provided an effective and versatile strategy to conquer the thermal stability and safety issues of cL-20 and contributes to the future application of high energy density energetic materials.

关键词： cL-20 Double-shell structure Thermal stability Safety performance Tannic acid Graphene sheets

Global well-posedness for 2D inhomogeneous asymmetric fluids with large initial data

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Science china Mathematics 2024年第3期67卷 527-556页

作者： chenyin Qian Beibei he Ting Zhang School of Mathematical Sciences Zhejiang Normal UniversityJinhua 321004China School of Mathematical Sciences Zhejiang UniversityHangzhou 310058China

In this paper, by using time-weighted global estimates and the Lagrangian approach, we first investigate the global existence and uniqueness of the solution for the 2D inhomogeneous incompressible asymmetric fluids with the initial(angular) velocity being located in sub-critical Sobolev spaces H^(s)(R^(2))(0nd the initial density being bounded from above and below by some positive constants. The global unique solvability of the 2D incompressible inhomogeneous asymmetric fluids with the initial data in the critical Besov space(u_(0), w_(0))∈˙B^(0)_(2,1)(R^(2))andρ^(−1)−1∈˙B^(ε)_(2/ε),1(R^(2))is established. In particular, the uniqueness of the solution is also obtained without any more regularity assumptions on the initial density which is an improvement on the recent result of Abidi and Gui(2021) for the 2D inhomogeneous incompressible navierStokes system.

关键词： inhomogeneous asymmetric fluids Littlewood-Paley theory Besov spaces global well-posedness

A Systematic Review and Performance Evaluation of Open-Source Tools for Smart contract Vulnerability Detection

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computers, Materials & continua 2024年第7期80卷 995-1032页

作者： Yaqiong he Jinlin Fan Huaiguang Wu School of computer Science and Technology Zhengzhou University of Light IndustryZhengzhou450001China

With the rise of blockchain technology,the security issues of smart contracts have become increasingly *** the availability of numerous smart contract vulnerability detection tools,many face challenges such as slow updates,usability issues,and limited installation *** challenges hinder the adoption and practicality of these *** paper examines smart contract vulnerability detection tools from 2016 to 2023,sourced from the Web of Science(WOS)and Google *** systematically collecting,screening,and synthesizing relevant research,38 open-source tools that provide installation methods were selected for further *** a developer’s perspective,this paper offers a comprehensive survey of these 38 open-source tools,discussing their operating principles,installation methods,environmental dependencies,update frequencies,and installation *** on this,we propose an Ethereum smart contract vulnerability detection *** framework enables developers to easily utilize various detection tools and accurately analyze contract security *** validate the framework’s stability,over 1700 h of testing were ***,a comprehensive performance test was performed on the mainstream detection tools integrated within the framework,assessing their hardware requirements and vulnerability detection *** results indicate that the Slither tool demonstrates satisfactory performance in terms of system resource consumption and vulnerability detection *** study represents the first performance evaluation of testing tools in this domain,providing significant reference value.

关键词： Blockchain security ethereum smart contracts detection tools evaluation

Image Segmentation-P300 Selector: A Brain–computer Interface System for Target Selection

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computers, Materials & continua 2024年第5期79卷 2505-2522页

作者： Hang Sun changsheng Li he Zhang Mechanical Engineering Nanjing University of Science and TechnologyNanjing210018China

Brain–computer interface (BcI) systems, such as the P300 speller, enable patients to express intentions withoutnecessitating extensive ***, the complexity of operational instructions and the slow pace of characterspelling pose challenges for some patients. In this paper, an image segmentation P300 selector based on YOLOv7-mask and DeepSORT is proposed. The proposed system utilizes a camera to capture real-world objects forclassification and tracking. By applying predefined stimulation rules and object-specificmasks, the proposed systemtriggers stimuli associated with the objects displayed on the screen, inducing the generation of P300 signals in thepatient’s brain. Its video processing mechanism enables the system to identify the target the patient is focusing oneven if the object is partially obscured, overlapped, moving, or changing in number. The system alters the target’scolor display, thereby conveying the patient’s intentions to caregivers. The data analysis revealed that the selfrecognitionaccuracy of the subjects using this method was between 92% and 100%, and the cross-subject P300recognition precision was 81.9%–92.1%. This means that simple instructions such as “Do not worry, just focuson what you desire” effectively discerned the patient’s intentions using the Image Segmentation-P300 selector. Thisapproach provides cost-effective support and allows patients with communication difficulties to easily express theirneeds.

关键词： Brain-computer interface deep learning electroencephalogram P300 YOLOv7-mask

Direct observation of ordered-disordered structural transition of MoS_(2)-confined ionic liquids

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chinese Journal of chemical Engineering 2024年第8期72卷 126-132页

作者： Yumiao Lu Weilu Ding Kun Li Yanlei Wang Bobo cao Ruirui he Hongyan he cAS Key Laboratory of Green Process and Engineering State Key Laboratory of Mesoscience and EngineeringBeijing Key Laboratory of Ionic Liquids Clean ProcessInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China University of chinese Academy of Sciences Beijing 100049China Longzihu new Energy Laboratory Zhengzhou Institute of Emerging Industrial TechnologyZhengzhou 450000China

Ionic liquids(ILs)are an emerging class of media of fundamental importance for chemical engineering,especially due to their interaction with solid ***,we explore the growth phenomenon of surface-confined ILs and reveal a peculiar structural transition behavior from order to disorder above a threshold *** behavior can be explained by the variation of interfacial forces with increasing distance from the solid *** structural observation of different ILs highlights the influence of the ionic structure on the growth ***,the length of the alkyl chain in the cation is found to be a determining factor for the ordering ***,the thermal stability of surface-confined ILs is investigated in depth by controlling annealing *** is found that the ordered monolayer ILs exhibit high robustness against high *** findings provide new perspectives on the properties of surface-confined ILs and open up potential avenues for manipulating the structures of nanometer-thick IL films for various applications.

关键词： Ionic liquids(ILs) Surface-confined ILs Structural transition Thermal stability Interfacial forces

Restoring cosmological concordance with axion-like early dark energy and dark matter characterized by a constant equation of state?

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communications in Theoretical Physics 2024年第7期76卷 74-82页

作者： Yan-Hong Yao Xin-he Meng School of Physics and Astronomy Sun Yatsen University 2 Daxue RoadTangjiaZhuhaiChina School of Physics Nankai University 94 Weijin RoadNankaiTianjinChina

The Hubble tension persists as a challenge in *** early dark energy(EDE)models,initially considered the most promising for alleviating the Hubble tension,fall short of addressing the issue without exacerbating other tensions,such as the S_(8)*** that a negative dark matter(DM)equation of state(EoS)parameter is conducive to reduce the value of the σ_(8)parameter,we extend the axion-like EDE model in this paper by replacing the cold dark matter(cDM)with DM characterized by a constant EoS w_(dm)(referred to as WDM hereafter).We then impose constraints on this axion-like EDE extension model,along with three other models:the axion-like EDE model,ΛWDM,and Λ*** constraints are derived from a comprehensive analysis incorporating data from the Planck 2018 cosmic microwave background,baryon acoustic oscillations,and the Pantheon compilation,as well as a prior on H_(0)(i.e.H_(0)=73.04±1.04,based on the latest local measurement by Riess et al)and a Gaussianized prior on S_(8)(i.e.S_(8)=0.766±0.017,determined through the joint analysis of KID1000+BOSS+2dLenS).We find that although the new model maintains the ability to alleviate the Hubble tension to~1.4σ,it still exacerbates the S_(8)tension to a level similar to that of the axion-like EDE model.

关键词： Hubble tension early dark energy noncold dark matter S8 tension

Infinitely many dichotomous solutions for the Schrödinger-Poisson system

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Science china Mathematics 2024年第9期67卷 2049-2070页

作者： Yuke he Benniao Li Wei Long School of Mathematics and Statistics and Jiangxi Provincial center for Applied Mathematics Jiangxi Normal UniversityNanchang 330022China

In this paper,we consider the following Schrodinger-Poisson system{-ε^(2)Δu+V(x)u+K(x)Φ(x)u=|u|^(p-1)u in R^(n),-ΔΦ(x)=K(x)u^(2)in Rn,,where e is a small parameter,1n+2/n-2,n∈[3,6],and V(x)and K(x)are potential functions with different decay at *** first prove the non-degeneracy of a radial low-energy ***,by using the non-degenerate solution,we construct a new type of infinitely many solutions for the above system,which are called“dichotomous solutions”,i.e.,these solutions concentrate both in a bounded domain and near infinity.

关键词： dichotomous solutions non-degeneracy Schrodinger-Poisson system

A signaling cascade mediating fruit trait development via phosphorylation-modulated nuclear accumulation of JAZ repressor

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Journal of Integrative Plant Biology 2024年第6期66卷 1106-1125页

作者： Wei Wang Jinyao Ouyang Yating Li changsheng Zhai Bing he Huahan Si Kunsong chen Jocelyn K.c.Rose Wensuo Jia college of Horticulture China Agricultural UniversityBeijing 100193China college of Agriculture and Biotechnology Zhejiang UniversityZijingang CampusHangzhou 310058China Plant Biology Section School of Integrative Plant ScienceCornell UniversityIthaca14853NYUSA Institute of Horticulture crops Xinjiang Academy of Agricultural SciencesUrumqi 830000China

It is generally accepted that jasmonate-ZIM domain(JAZ)repressors act to mediate jasmonate(JA)signaling via cOROnATInE-InSEnSITIVE1(cOI1)-mediated ***,we report a cryptic signaling cascade where a JAZ repressor,FvJAZ12,mediates multiple signaling inputs via phosphorylation-modulated subcellular translocation rather than the cOI1-mediated degradation mechanism in strawberry(Fragaria vesca).FvJAZ12 acts to regulate flavor metabolism and defense response,and was found to be the target of Fv MPK6,a mitogen-activated protein kinase that is capable of responding to multiple signal ***6 phosphorylates FvJAZ12 at the amino acid residues S179 and T183 adjacent to the PY residues,thereby attenuating its nuclear accumulation and relieving its repression for FvMYc2,which acts to control the expression of lipoxygenase 3(FvLOX3),an important gene involved in JA biosynthesis and a diverse array of cellular *** data reveal a previously unreported mechanism for JA signaling and decipher a signaling cascade that links multiple signaling inputs with fruit trait development.

关键词： defense response JAZ repressor phosphorylation strawberry subcellular translocation