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基因组构成和胞质对油菜和甘蓝杂交衍生的再合成双二倍体和倍半二倍体花瓣颜色的影响

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国外作物育种 2003年第3期22卷 37-38页

作者： B.zhang c.m.lu 谢国禄

通过胚珠培养合成甘蓝型油菜将外源基因渗入油菜中以及伴随的脂肪酸组成的变化

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国外作物育种 2002年第6期21卷 41-41页

作者： c.m.lu 邱敦莲等

Unraveling the origins of PGY-sRNA-6,BZL-sRNA-20,and XKc-sRNA-h3

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Science china Life Sciences 2025年

作者： Shanfa lu State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs Institute of Medicinal Plant DevelopmentChinese Academy of Medical Sciences&Peking Union Medical College Engineering Research center of chinese medicine Resource Ministry of Education

Dear Editor,The regulatory role of herbal sRNAs in humans and animals is an interesting research ***,current evidence is insufficient to conclude that herbal sRNAs are novel precision medicines.I previously showed that HJT-sRNA-m1-HJT-sRNA-m8,identified as herbal sRNAs previously (Du et al.,2019),may be derived from humans and/or animals(lu,2023).To minimize errors during herbal sRNA analysis,I provided a list of matters needing special attention and proposed problem-solving solutions for researchers working on sRNA cross-kingdom regulation (lu,2023).

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Ru doping triggering reconstruction of cobalt phosphide for coupling glycerol electrooxidation with seawater electrolysis

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Journal of Energy chemistry 2025年第1期100卷 317-326页

作者： Binglu Deng Jie Shen Jinxing lu chuqiang Huang Zhuoyuan chen Feng Peng Yunpeng Liu School of materials Science and Hydrogen Energy Foshan University School of chemistry and chemical Engineering Guangzhou University Guangdong Key Laboratory for Hydrogen Energy Technologies

Seawater electrolysis is a promising approach for sustainable energy without relying on precious ***,the large-scale seawater electrolysis is hindered by low catalytic efficiency and severe anode corrosion caused by the harmful *** contrast to the oxygen evolution reaction （OER）and chlorin ion oxidation reaction （clOR）,glycerol oxidation reaction （GOR） is more thermodynamically and kinetically favorable ***,a Ru doping cobalt phosphide （Ru-coP2） is proposed as a robust bifunctional electrocatalyst for seawater electrolysis and GOR,for the concurrent productions of hydrogen and value-added *** in situ and ex situ characterization analyses demonstrated that Ru doping featured in the dynamic reconstruction process from Ru-coP2to Ru-coOOH,accounting for the superior GOR *** coupling GOR with hydrogen evolution was realized by employing Ru-coP2as both anode and cathode,requiring only a low voltage of 1.43 V at 100 mA cm-2,which was 250 m V lower than that in alkaline *** work guides the design of bifunctional electrocatalysts for energy-efficient seawater electrolysis coupled with biomass resource upcycling.

关键词： Anodes

High Fe‑Loading Single‑Atom catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy

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Nano-micro Letters 2025年第2期17卷 187-203页

作者： Si chen Fang Huang Lijie mao Zhimin Zhang Han Lin Qixin Yan Xiangyu lu Jianlin Shi Department of cardiology Shanghai Tenth People’s HospitalSchool of MedicineTongji UniversityShanghai 200092People’s Republic of China Shanghai Institute of ceramics Chinese Academy of SciencesShanghai 200050People’s Republic of China Shanghai Frontiers Science center of Nanocatalytic medicine School of MedicineTongji UniversityShanghai 200092People’s Republic of China

The current single-atom catalysts(SAcs)for medicine still suffer from the limited active site ***,we develop a synthetic method capable of increasing both the metal loading and mass-specific activity of SAcs by exchanging zinc with *** constructed iron SAcs(h^(3)-FNc)with a high metal loading of 6.27 wt%and an optimized adjacent Fe distance of~4 A exhibit excellent oxidase-like catalytic performance without significant activity decay after being stored for six months and promising antibacterial ***,a“density effect”has been found at a high-enough metal doping amount,at which individual active sites become close enough to interact with each other and alter the electronic structure,resulting in significantly boosted intrinsic activity of single-atomic iron sites in h^(3)-FNcs by 2.3 times compared to low-and medium-loading ***,the overall catalytic activity of h^(3)-FNc is highly improved,with mass activity and metal mass-specific activity that are,respectively,66 and 315 times higher than those of commercial Pt/*** addition,h^(3)-FNcs demonstrate efficiently enhanced capability in catalyzing oxygen reduction into superoxide anion(O_(2)·^(−))and glutathione(GSH)*** in vitro and in vivo assays demonstrate the superior antibacterial efficacy of h^(3)-FNcs in promoting wound *** work presents an intriguing activity-enhancement effect in catalysts and exhibits impressive therapeutic efficacy in combating bacterial infections.

关键词： Nanocatalytic medicine Single-atom catalysts Reactive oxygen species(ROS) High metal loading Oxidase catalysis

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Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases

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Neural Regeneration Research 2025年第8期20卷 2373-2381页

作者： Lifang Zhao mingkai Zhang Qimeng Li Xuemin Wang Jie lu Ying Han Yanning cai Department of clinical Biobank Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Geriatric medical Research center BeijingChina Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Radiology and Nuclear medicine Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Key Laboratory of magnetic Resonance Imaging and Brain Informatics BeijingChina Key Laboratory of Neurodegenerative diseases Ministry of EducationBeijingChina School of Biomedical Engineering Hainan UniversityHaikouHainan ProvinceChina center of Alzheimer’s Disease Beijing Institute for Brain DisordersBeijingChina National clinical Research center for Geriatric Diseases BeijingChina Institute of Biomedical Engineering Shenzhen Bay LaboratoryGaoke Innovation CenterShenzhenGuangdong ProvinceChina Department of Neurobiology Xuanwu HospitalCapital Medical UniversityBeijingChina

Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative ***,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°*** aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large *** samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on cognitive Decline *** samples were stored at-80°c for up to 6 years before being used in this *** results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage ***,the level of total tau showed a negative correlation with sample storage ***,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage *** was not observed in individuals with cognitive ***,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage ***,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's ***,in cohort studies,it is important to consider the impact of storage time on the overall results.

关键词： Alzheimer’s disease amyloid-β diagnostic ability glial fibrillary acidic protein neurodegeneration neurofilament light chain plasma biomarkers single molecule array storage time tau

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metal-organic frameworks with dinuclear metal centers for synergistically boosting cO2 photoreduction

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Science china chemistry 2025年第1期68卷 201-208页

作者： Hui-Feng Wang Wen-Jie Shi Yu-Xin Yang Bao-Xia Dong Tong-Bu lu Di-chang Zhong School of chemistry and chemical Engineering Yangzhou University Institute for New Energy materials and Low carbon Technologies School of Materials Science and Engineering Tianjin University of Technology

Dinuclear metal synergistic catalysis （DmSc） has been proved powerful in boosting cO2reduction,while this has not been achieved in heterogeneous catalysts with long-range order *** this study,we,by introduction of metal catalytic centers into an indium-based metal-organic framework （mOF）,obtained a series of isostructural In-mOFs,including three mOFs with mononuclear metal catalytic center （m-In）,three mOFs with dinuclear homometallic catalytic centers （mm-In）,and three mOFs with dinuclear heterometallic catalytic centers (mm’-In,m/m’=co（II）,Ni（II）,Zn（II）).It was found that all these mOFs can serve as catalysts for photochemical cO2reduction to *** with m-In,the catalytic activities of mm-In were obviously enhanced,and that of mm’-In was further significantly *** example,the cO yield of co Zn-In reaches a record value of 12,700μmol g-1h-1,which is 4.0,8.1,9.4,and 18.6-fold higher than that of co co-In,Zn Zn-In,co-In,and Zn-In,***,the catalytic activities of co Ni-In and Ni Zn-In also show different fold increase than those of corresponding dinuclear homometallic and mononuclear metallic *** results of control experiments and theoretical calculation reveal that the higher catalytic activities of mm-In over m-In can be ascribed to the DmSc effect,and the higher catalytic activity of mm’-In over mm-In can be ascribed to the strengthened DmSc *** work reveals the relationship between DmSc effect and bimetal centers in cO2reduction,which provides new insights into the DmSc and paves a new way to design highly active catalysts for photochemical cO2reduction.

关键词： metal-organic frameworks dinuclear metal centers synergistic catalysis cO2 reduction photocatalysis

cO2-mediated bicarbonate conversion to concentrated formate in a cEm-based electrolyzer

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Journal of Energy chemistry 2025年第1期100卷 605-611页

作者： Haocheng Xiong Donghuan Wu Haonan Li Andrew Li Qikun Hu Siyao Song Bingjun Xu Qi lu State Key Laboratory of chemical Engineering Department of Chemical Engineering Tsinghua University college of chemistry and molecular Engineering Peking University Ordos Laboratory

Renewable energy-driven bicarbonate conversion to valuable chemicals presents an attractive strategy for mitigating cO2emissions,as bicarbonate can be efficiently generated from the capture of atmospheric cO2using alkaline solutions with reactive *** this work,we present a cO2-mediated bicarbonate conversion to pure formate using a cation exchange membrane-based electrolyzer with a 25 cm2electrode *** electrolysis achieved selectivities exceeding 75%for formate at a total current of 2.5 A,achieving formate concentrations up to 1.2 m and yields as high as 95%over extended *** techno-economic assessment confirmed the economic viability of the process,highlighting the potential for bicarbonate electrolysis as a sustainable method for producing valuable chemicals.

关键词： Electrocatalysis Techno-economic assessments Electrochemistry Flow electrolyzer

Spatiotemporal characteristics and influencing factors of vegetation water use efficiency on the Tibetan Plateau in 2001–2020

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Journal of Geographical Sciences 2025年第1期35卷 39-64页

作者： HE chenyang WANG Yanjiao YAN Feng lu Qi School of Ecological and Environmental Science East China Normal University Institute of Ecological conservation and Restoration Chinese Academy of Forestry National climate center China Meteorological Administration

Water use efficiency （WUE）,as a pivotal indicator of the coupling degree within the carbon–water cycle of ecosystems,holds considerable importance in assessment of the carbon–water balance within terrestrial ***,in the context of global warming,WUE evolution and its primary drivers on the Tibetan Plateau remain *** study employed the ensemble empirical mode decomposition method and the random forest algorithm to decipher the nonlinear trends and drivers of WUE on the Tibetan Plateau in 2001–*** indicated an annual mean WUE of 0.8088 gc/mm·m2across the plateau,with a spatial gradient reflecting decrease from the southeast toward the *** manifesting monotonous trends of increase or decrease in WUE accounted for 23.64%and 9.69%of the total,***,66.67%of the region exhibited trend reversals,i.e.,39.94%of the area of the Tibetan Plateau showed transition from a trend of increase to a trend of decrease,and 26.73%of the area demonstrated a shift from a trend of decrease to a trend of *** factors accounted for 70.79%of the variability in *** leaf area index and temperature served as the major driving forces of WUE variation.

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