检索结果-南通市图书馆

genomic and transcriptomic analysis unveils population evolution and development of pesticide resistance in fall armyworm Spodoptera frugiperda

引用

Protein & cell 2022年第7期13卷 513-531页

作者： Furong gui Tianming Lan Yue Zhao Wei guo Yang Dong Dongming Fang Huan Liu Haimeng Li Hongli Wang Ruoshi Hao Xiaofang cheng Yahong Li Pengcheng Yang Sunil kumar Sahu Yaping chen Le cheng Shuqi He Ping Liu guangyi Fan Haorong Lu guohai Hu Wei Dong Bin chen Yuan Jiang Yongwei Zhang Hanhong Xu Fei Lin Bernard Slippers Alisa Postma Matthew Jackson Birhan Addisie Abate Kassahun Tesfaye Aschalew Lemma Demie Meseret Destaw Bayeleygne Dawit Tesfaye Degefu Feng chen Paul K.Kuria Zachary M.Kinyua Tong-Xian Liu Huanming Yang Fangneng Huang Xin Liu Jun Sheng Le Kang State Key Laboratory for conservation and Utilization of Bioresources in Yunnan Yunnan Agricultural UniversityKunming 650201China State Key Laboratory of Agricultural genomics BGI-ShenzhenShenzhen 518083China State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of ZoologyChinese Academy of SciencesBeijing 100101China Beijing Institutes of Life Science Chinese Academy of SciencesBeijing 100101China MgI BGI-ShenzhenShenzhen 518083China BgI-Qingdao BGI-ShenzhenQingdao 266555China BgI-Yunnan No.389 Haiyuan RoadHigh-tech Development ZoneKunming 650106China china National geneBank Jinsha RoadDapeng New DistrictShenzhen 518120China Department of Biology University of Copenhagen2100 CopenhagenDenmark guangdong Provincial Key Laboratory of genome Read and Write BGI-ShenzhenShenzhen 518120China guangdong Provincial Academician Workstation of BgI Synthetic genomics BGI-ShenzhenShenzhen 518120China Yunnan Plateau characteristic Agriculture Industry Research Institute Kunming 650201China college of Plant Health and Medicine Qingdao Agricultural UniversityQingdao 266109China Department of Entomology Louisiana State University Agricultural CenterBaton RougeLA 70803USA cAS center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijing 100101China Yunnan Plant Protection and Quarantine Station Kunming 650034China State Key Laboratory for conservation and Utilization of Subtropical Agro-Bioresources South China Agricultural UniversityGuangzhou 510642China BgI-Americas One Broadway14th FloorCambridgeMA 02142USA Departme nt of Biochemistry Gen etics and MicrobiologyForestry and Agricultural Biotech no logy InstituteUn iversity of PretoriaPretoriaSouth Africa Ethiopian Biotechnology Institute Addis AbabaEthiopia college of Natural Science Addis Ababa UniversityAddis AbabaEthiopia Melkassa Agricultural Research center Ethiopian Institute of Agricultural ResearchMelkassaAddis AbabaEthiopia Kenya Agricultural and Livestock Res

The fall armyworm(FAW),Spodoptera frugiperda,is a destructive pest native to America and has recently become an invasive insect pest in *** of its rapid spread and great risks in china,understanding of FAW genetic background and pesticide resistance is urgent and essential to develop effective management ***,we assembled a chromosome-level genome of a male FAW(SFynMstLFR)and compared re-sequencing results of the populations from America,Africa,and *** identification of 163 individuals collected from America,Africa and china showed that both c and R strains were found in the American pop-ulations,while only c strain was found in the chinese and African ***,population geno-mics analysis showed that populations from Africa and china have close relationship with significantly genetic differentiation from American *** toge-ther,FAWs invaded into china were most likely origi-nated from *** genomics analysis displayed that the cytochrome p450 gene family is extremely expanded to 425 members in FAW,of which 283 genes are specific to *** of chinese populations with twenty-three pesticides showed the variant patterns of transcriptome profiles,and several detoxification genes such as AOX,UgT and gST spe-cially responded to the *** findings will be useful in developing effective strategies for manage-ment of FAW in china and other invaded areas.

关键词： Spodoptera frugiperda chromosome-level genome population differentiation cytochrome p450 pesticides

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Kinetics of the Oxidation of Hydrogen Sulfide by Atmospheric Oxygen in an Aqueous Medium

引用

Journal of Atmospheric Science Research 2021年第3期4卷 46-59页

作者： Deepak Singh Rathore Vimlesh kumar Meena chandra Pal Singh chandel Krishna Swarup gupta Atmospheric chemistry Laboratory Department of ChemistryUniversity of RajasthanJaipur302004India

Hydrogen sulfide is an important acid rain precursor and this led us to investigate the kinetics of its oxidation in aqueous phase by atmospheric *** kinetics was followed by measuring the depletion of oxygen in a *** reaction was studied under pseudo order conditions with[H2S]in *** kinetics followed the rate law:-d[O_(2)]/dt=k[S][O_(2)]_(t)(A)Where[S]represents the total concentration of hydrogen sulfide,[O_(2)]_(t)is the concentration of oxygen at time t and k is the second order rate *** equilibria(B-c)govern the dissolution of H_(2)S;the sulfide ion in water forms different species:H_(2)S K1→←HS^(-)+H_(+)(B)HS^(-)K2→←S^(2-)+H^(+)(c)Where K_(1)and K_(2)are first and second dissociation constants of H_(2)***,H_(2)S is present as undissociated H_(2)S,HS^(-)and S^(2-)ions,nature of[H^(+)]dependence of reaction rate required only HS^(-)to be reactive and *** rate law(A)on including[H^(+)]dependence became Equation(D).-d[O_(2)]/dt=k_(1)K_(1)[H^(+)][S][O_(2)]_(t)/([H^(+)]^(2)+K_(1)[H^(+)]+K_(1)K_(2))(D)Our results indicate anthropogenic VOcs such as acetanilide,benzene,ethanol,aniline,toluene,benzamide,o-xylene,m-xylene,p-xylene and anisole to have no significant effect on the reaction rate and any observed small effect is within the uncertainty of the rate measurements.

关键词： Hydrogen sulfide Oxygen Oxidation Kinetics Effect of organics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Response of consumer Food Price Index(cFPI)due to the Impact of Pandemic cOVID-19 on Indian Agriculture Sector

引用

NASS Journal of Agricultural Sciences 2021年第1期3卷 29-35页

作者： Digvijay Pandey Nidhi Verma Tajamul Islam Wegayehu Enbeyle Binay kumar Pandey PMadhusudana Patra Department of Technical Education IETLucknowIndia government P.g college for Women RohtakIndia Department of Botany University of KashmirSrinagarJ&K190006India Department of Biostatistics Mizan-Tepi UniversityTepiEthiopia Department of IT GovindBallabh Pant University of Agriculture and TechnologyIndia SRM-DBT Facility SRM Institute of science and technologyChennaiIndia

India is an agricultural country and a core source of income for the world *** Indian economy is greatly depending on agriculture that is decrease day by day due to pandemic *** is a major exporter of many crop ***,Thailand,and Vietnam are the major exports of rice if these stopped exports it reduces the economy up to 15%.A related circumstance is built up with diverse yields too like wheat,sunflower whose fare has been stationary by Kazakhstan,Serbia *** India,the end of April is the main source of income to farmers because they sell their rabi crops(wheat,mustard,maize,lentil,chilies,gram,tomatoes)in the market drastically decreases of cFPI may lead to the distress of Indian agricultural *** change over time in the price of options on wheat futures reveals increased price volatility in response to growing uncertainty about the cOVID-19 impacts.

关键词： coronavirus cOVID-19 2019-ncoV Pandemic Public health emergency Middle-Eastern-Respiratory Syndrome(MERS) consumer food price index(cFPI)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

印度岩画概况及其研究

引用

内蒙古大学艺术学院学报 2016年第2期13卷 14-30页

作者：吉日拉吉.库马尔张嘉馨肖波达耶尔巴格教育学院中央民族大学民族学与社会学院北京100089 南京师范大学社会发展学院南京210097

本文对印度岩画进行了全面而概要的介绍;着重探讨了印度最主要的岩画点"比莫贝特卡岩画点"(Bhimbetka)、"达拉奇—查丹岩画点"(Daraki-chattan)、"查特普吉纳什·纳拉岩画点"(chaturbhujnath Nala)的发现和研究现状;并对印度岩画的... 详细信息

本文对印度岩画进行了全面而概要的介绍;着重探讨了印度最主要的岩画点"比莫贝特卡岩画点"(Bhimbetka)、"达拉奇—查丹岩画点"(Daraki-chattan)、"查特普吉纳什·纳拉岩画点"(chaturbhujnath Nala)的发现和研究现状;并对印度岩画的断代方法和年代学序列进行了论述;随后将印度岩画分为中心区和边境区两大部分;其中印度中心区的岩画是印度岩画最集中、最重要的区域;按历时的顺序,分别从旧石器时代、中石器时代、新石器时代和历史时期对中心区岩画进行了分析;边境区则选取了7个岩画相对丰富的邦进行探讨;本文旨在对印度岩画进行全面分析的基础上探讨其年代序列、风格变迁和内涵意义。

关键词：印度岩画岩刻岩绘旧石器时代中石器时代新石器时代历史时期断代风格变迁

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

鲍曼不动杆菌荚膜通过抑制PI3K/Akt/mTOR信号通路促进鼠巨噬细胞自噬和凋亡

引用

江苏大学学报（医学版） 2020年第1期30卷 1-6页

作者：韩长鸣戴晓玥段前梅仇圣刚石立新夏雯邹治情 Dinsh kumar K 吴亮阴晴许化溪江苏大学医学院江苏镇江212013 扬州市江都人民医院神经内科江苏扬州225200 江苏大学附属医院检验科江苏镇江212001

目的:探讨不同厚度荚膜的鲍曼不动杆菌诱导鼠Raw 264.7巨噬细胞自噬和凋亡的能力及潜在的机制。方法:从肺炎患者痰液中分离鉴定鲍曼不动杆菌,以刚果红染色法染色细菌荚膜并筛选荚膜厚度显著不同的菌株用于后续研究。分别以厚荚膜株(Ab-H... 详细信息

目的:探讨不同厚度荚膜的鲍曼不动杆菌诱导鼠Raw 264.7巨噬细胞自噬和凋亡的能力及潜在的机制。方法:从肺炎患者痰液中分离鉴定鲍曼不动杆菌,以刚果红染色法染色细菌荚膜并筛选荚膜厚度显著不同的菌株用于后续研究。分别以厚荚膜株(Ab-H株)和薄荚膜株(Ab-B株)感染Raw 264.7细胞,于感染后1 h、3 h和6 h时收集细胞,采用免疫印迹法检测细胞自噬相关蛋白Lc-3和Beclin-1表达,以及PI3K、Akt和mTOR磷酸化水平,采用流式细胞术检测细胞活性氧生成量和凋亡率。结果:鲍曼不动杆菌经刚果红染色后,菌体染成紫黑色,背景染成红色,荚膜不着色,可以清晰地观察到细菌荚膜厚度。筛选出两株荚膜厚度差异显著的鲍曼不动杆菌,分别为Ab-H株和Ab-B株。上述菌株感染Raw 264.7细胞后均可以诱导细胞自噬和凋亡,并增加细胞活性氧生成量,PI3K、Akt和mTOR的磷酸化水平受到显著抑制,且抑制作用随着时间延长而增加(Pcline-1表达量和活性氧生成量显著高于Ab-B株(P<0.05)。结论:鲍曼不动杆菌能够诱导Raw 264.7细胞自噬和凋亡的发生,诱导能力与细菌荚膜厚度呈正相关;厚荚膜鲍曼不动杆菌有更强的诱导Raw 264.7细胞活性氧生成能力,以及抑制PI3K/Akt/mTOR信号通路活化能力,最终导致Raw 264.7细胞自噬和凋亡。

关键词：鲍曼不动杆菌荚膜细胞凋亡 PI3K/Akt/mTOR信号通路

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

2001—2002年印度喀拉拉邦坎纳区公立和私立医疗卫生机构合作开展结核病控制项目的成本及成本—效益分析

引用

国际结核病与肺部疾病杂志 2008年第2期3卷 78-83页

作者： O. Ferroussier M.K.A. kumar R. K. Dewan P.K.J. Nair S. Sahu D. F. Wares K. Laserson c. Wells R. granich L. S. chauhan 刘宇红（译）何广学（校）王雪静（审） International Research and Programs Branch Division of Tuberculosis Elimination Canters for Disease Control and Prevention Atlanta Georgia USA District Health Office Kannur Office of the World Health Organization Representative to India New Delhi central Tuberculosis Division Directorate General of Health Services Ministry of Health and Family Welfare New Delhi India 不详

背景:对于公立和私立机构合作(PPM)诊断和治疗结核病的成本效益方面的了解尚不足。设计:从新的国家结核病防治规划(RNTcP)角度,评价印度坎纳地区私立机构实验室开展PPM项目的花费及成本-效益。我们估算了每聘用并维持一个服务提供者的花... 详细信息

背景:对于公立和私立机构合作(PPM)诊断和治疗结核病的成本效益方面的了解尚不足。设计:从新的国家结核病防治规划(RNTcP)角度,评价印度坎纳地区私立机构实验室开展PPM项目的花费及成本-效益。我们估算了每聘用并维持一个服务提供者的花费,估算了在不同效率假设的情况下多发现1例病人的花费、以及多成功治疗1例病人的花费。有关这些干预措施的花费的数据来自于国家结核病控制规划的登记资料,治疗花费的估算基于国家结核病控制规划的病例管理方案。结果:本项目每年总的估算花费为8 712～11611美元,平均每聘用1个私立服务提供者的费用从22～54美元不等,私立机构多诊断1例肺结核病人的花费为14～18美元。多登记1个病人,最保守的估算需花费29～36美元。每成功治疗1例抗酸杆菌阳性的病人约花费47～51美元。提高报告率会改善成本效益。结论:与公立卫生机构的诊断费用相比,需要明确这项干预措施是否对不同实施级别的公共卫生系统在经济上具有吸引力;如需扩展PPM项目,需要明确补充资源的需求。

关键词：印度结核公立-私立机构合作成本-效益

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

MESA P2实验对弱混合角的测量（英文）

引用

中国科学技术大学学报 2016年第6期46卷 481-487页

作者： BERgER N. AULENBAcHER K. BAUNAcK S. BEcKER D. DIEFENBAcH J. gERIcKE M. gERZ K. HERBERTZ R. kumar K. MAAS F. MOLITOR M. PINIEIRO D.R. SOROKIN I. SOUDER P. SPIESBERgER H. TYUKIN A. TYUKIN V. ZIMMERMANN M. 德国约翰内斯堡大学核物理学院卓越研究中心德国美因茨亥姆霍兹公司德国美因茨曼尼托巴大学天文物理学系加拿大温尼伯格石溪大学天文物理学系美国石溪锡拉丘兹大学物理系美国锡拉丘兹德国约翰内斯堡大学物理学院卓越研究中心德国美因茨

美因茨的P2实验致力于通过电子-质子散射将弱混合角sin^2θ_W的测量精确度提高到0.13%.为了压低由于质子结构和箱图贡献的不确定性,选择了低平均四动量转移Q2(4.5×10^(-3)geV2/c2)和低束流能量(155 Me V).为了达到实验要求的巨大统计量... 详细信息

美因茨的P2实验致力于通过电子-质子散射将弱混合角sin^2θ_W的测量精确度提高到0.13%.为了压低由于质子结构和箱图贡献的不确定性,选择了低平均四动量转移Q2(4.5×10^(-3)geV2/c2)和低束流能量(155 Me V).为了达到实验要求的巨大统计量,新的美因茨能量恢复超导加速器(MESA)正在建设中.本文描述了测量的动机、实验和加速器面临的挑战以及解决问题的方案.

关键词：弱混合角宇称破缺电子散射

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fungal diversity notes 1036-1150:taxonomic and phylogenetic contributions on genera and species of fungal taxa

引用

Fungal Diversity 2019年第3期96卷 1-242页

作者： Kevin D.Hyde Danushka S.Tennakoon Rajesh Jeewon DJayarama Bhat Sajeewa S.N.Maharachchikumbura Walter Rossi Marco Leonardi Hyang Burm Lee Hye Yeon Mun Jos Houbraken Thuong T.T.Nguyen Sun Jeong Jeon Jens christian Frisvad Dhanushka N.Wanasinghe Robert Lucking Andre Aptroot Marcela E.S.caceres Samantha c.Karunarathna Sinang Hongsanan Rungtiwa Phookamsak Nimali Ide Silva Kasun M.Thambugala Ruvishika S.Jayawardena Indunil c.Senanayake Saranyaphat Boonmee Jie chen Zong-Long Luo chayanard Phukhamsakda Olinto L.Pereira Vanessa P.Abreu Andre Wilson campos Rosado Buyck Bart Emile Randrianjohany Vale rie Hofstetter Tatiana B.gibertoni Adriene Mayrada Silva Soares Helio Longoni Plautz Jr Helen Maria Pontes Sotao William Kalhy Silva Xavier Jadson Diogo Pereira Bezerra Thays gabrielle Linsde Oliveira cristina Mariade Souza-Motta Oliane Maria correia Magalhaes Digvijayini Bundhun Dulanjalee Harishchandra Ishara S.Manawasinghe Wei Dong Sheng-Nan Zhang Dan-Feng Bao Milan c.Samarakoon Dhandevi Pem Anuruddha Karunarathna chuan-gen Lin Jing Yang Rekhani H.Perera Vinit kumar Shi-Ke Huang Monika c.Dayarathne Anusha H.Ekanayaka Subashini c.Jayasiri Yuanpin Xiao Sirinapa Konta Tuula Niskanen Kare Liimatainen Yu-cheng Dai Xiao-Hong Ji Xue-Mei Tian Armin Mesic Sanjay K.Singh Kunthida Phutthacharoen Lei cai Touny Sorvongxay Vinodhini Thiyagaraja chada Norphanphoun Napalai chaiwan Yong-Zhong Lu Hong-Bo Jiang Jin-Feng Zhang Pranami D.Abeywickrama Janith V.S.Aluthmuhandiram Rashika S.Brahmanage Ming Zeng Thilini chethana Deping Wei Martina Reblova Jacques Fournier Jana Nekvindova Renan do Nascimento Barbosa Jose Ewerton Felintodos Santos Neiva Tintide Oliveira guo-Jie Li Damien Ertz Qiu-Ju Shang Alan J.L.Phillips chang-Hsin Kuo Erio camporesi Timur S.Bulgakov Saisamorn Lumyong E.B.gareth Jones Putarak chomnunti Eleni gentekaki Frank Bungartz Xiang-Yu Zeng Sally Fryar Zdenko Tkalcec Junmin Liang guangshuo Li Ting-chi Wen Paras Nath Singh Yusufjon gafforov Itthayakorn Promputtha Erandi Yasanthika Ishani D.goonasekara Rui-Lin Zhao Qi Zhao Paul M Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand East and central Asia Regional Office World Agroforestry Centre(ICRAF)Kunming 650201YunnanPeople’s Republic of China Department of Biology Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand Mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand Department of Plant Medicine National Chiayi University300 Syuefu RoadChiayi City 60004TaiwanPeople’s Republic of China Department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius Formerly Department of Botany Goa UniversityGoaIndia No.128/1-J Azad Housing SocietyCurcaGoa Velha 403108India Department of crop Sciences College of Agricultural and Marine SciencesSultan Qaboos UniversityPO Box 8123 Al KhoudOman Sect.Environmental Sciences Dept.MeSVAUniversity of L’Aquila67100 CoppitoAQItaly Division of Food Technology Biotechnology&AgrochemistryCollege of Agriculture&Life SciencesChonnam National UniversityGwangju 61186Korea Fungal Resources Research Division NNIBRSangju-si 37242Korea Westerdijk Fungal Biodiversity Institute Uppsalalaan 83584 CT UtrechtThe Netherlands Department of Biotechnology and Biomedicine DTUBioengineeringTechnical University of Denmark2800 Kongens LyngbyDenmark Botanischer garten und Botanisches Museum Berlin Freie Universitat BerlinKonigin-Luise-StraßBe 6-814195 BerlinGermany Laboratorio de Botanica/Liquenologia Instituto de BiocienciasUniversidade Federal de Mato Grosso do SulAvenida Costa e Silva s/nBairro UniversitarioCampo GrandeMatto Grosso do Sul CEP 79070-900Brazil Departamento de Biociencias Universidade Federal de SergipeItabaianaSergipe CEP:49500-000Brazil Shenzhen Key Laboratory of Microbial

This article is the tenth series of the Fungal Diversity Notes,where 114 taxa distributed in three phyla,ten classes,30 orders and 53 families are described and *** described in the present study include one new family(*** in Dothideomycetes),five new genera(caatingomyces,cryptoschizotrema,Neoacladium,Paramassaria and Trochilispora)and 71 new species,(*** thailandica,Amniculicola aquatica,***,Angustimassarina sylvatica,Blackwellomyces lateris,Boubovia gelatinosa,Buellia viridula,caatingomyces brasiliensis,calophoma humuli,camarosporidiella mori,canalisporium dehongense,cantharellus brunneopallidus,***,castanediella meliponae,coprinopsis psammophila,cordyceps succavus,cortinarius minusculus,***,Diaporthe italiana,***,Diatrypella delonicis,Dictyocheirospora aquadulcis,***,Digitodesmium chiangmaiense,Distoseptispora dehongensis,***,Dothiorella styphnolobii,Ellisembia aurea,Falciformispora aquatic,Fomitiporia carpinea,***,grammothele aurantiaca,***,Hermatomyces bauhiniae,Jahnula queenslandica,Kamalomyces mangrovei,Lecidella yunnanensis,Micarea squamulosa,Muriphaeosphaeria angustifoliae,Neoacladium indicum,Neodidymelliopsis sambuci,Neosetophoma miscanthi,***,Nodulosphaeria aquilegiae,***,Paramassaria samaneae,Penicillium circulare,***,***-pumilae,***,***,Phaeoisaria siamensis,Phaeopoacea asparagicola,Phaeosphaeria penniseti,Plectocarpon galapagoense,Porina sorediata,Pseudoberkleasmium chiangmaiense,Pyrenochaetopsis sinensis,Rhizophydium koreanum,Russula prasina,Sporoschisma chiangraiense,Stigmatomyces chamaemyiae,***,***,***,***,Thysanorea uniseptata,Torula breviconidiophora,***,Trochilispora schefflerae and Vaginatispora palmae).Further,twelve new combinations(*** cryptotrema,Prolixandromyces australi,***,***,***,P.

关键词： 71 new taxa Ascomycota Basidiomycota Dothideomycetes Eurotiomycetes Lecanoromycetes Leotiomycetes Pezizomycetes Phylogeny Taxonomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Inhibition of N-（4-hydroxyphenyl）retinamide induced autophagy at a lower dose enhances cell death in malignant glioma cells

引用

中国神经肿瘤杂志 2007年第4期5卷 282-282页

作者： Tiwari M Bajpai VK Sahasrabuddhe AA kumar A Sinha RA Behari S godbole MM carcinogenesis Department of Endocrinology Department of Neurosurgery Sanjay Gandhi Post Graduate Institute of Medical Sciences Raebareli Road Lucknow 2260140

The question whether chemotherapy induced autophagy is causative to the demise of the cells or is it a part of the survival mechanism activated during cellular distress is *** and we have previously demonstrated apoptosis inducing capacity of N-(4-hydroxyphenyl) retinamide (4-HPR) in malignant glioma *** provide evidences of 4-HPR induced autophagy at a lower concentration (5 muM).Sub optimal dose of 4-HPR treatment of malignant gliomas cell lines increased g2/M arrest whereas cell accumulated in S-phase at a higher concentration.4-HPR-induced autophagy was associated with acidic vacuole (AVO) formation and recruitment of microtubule-associated protein light chain 3 (Lc3).At higher concentration of 10 mum of 4-HPR glioma cells undergoing apoptosis manifested autophagic features indicated by autophagosome formation, AVO development and Lc3 localization.

关键词：抑细胞素氨基化合物羟苯基自体吞噬剂量细胞凋亡恶性神经胶质瘤

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

肾髓质的弱化在cT平扫中的可视化意义——应用呋塞米的效果如何?

引用

国际医学放射学杂志 2010年第4期 374-374页

作者： R.kumar c.Forsythe E.M.Webb B.M.Yeh 焦慧 Department of Radiology University of California San Francisco505 Parnassus AveBox 0628C-372CSan FranciscoCA 94143-0628USA

目的回顾性研究cT平扫所显示的呋塞米对肾髓质弱化作用的影响。材料与方法这项回顾性研究遵从HIPAA法案,经伦理委员会批准,免除知情同意书。这项研究包括289例行cT尿路成像

关键词：呋塞米弱化作用肾髓质平扫 cT

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：