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Fully integrated and broadband si-rich silicon nitride wavelength converter based on Bragg scattering intermodal four-wave mixing

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photonics research 2024年第3期12卷 I0001-I0010页

作者： VAleriO vitali thAlÍA DOmÍnGUeZ BUciO hAO liU JOsÉmAnUel lUQUe GOnZÁleZ FrAnciscO JUrADO-rOmerO AleJAnDrO OrteGA-mOÑUX Glenn chUrchill JAmes c.GAtes JAmes hillier niKOlAOs KAlFAGiAnnis DAniele melAti Jens h.schmiD ilAriA cristiAni pAVel cheBen J.GOnZAlO WAnGÜemert-pÉreZ ÑiGO mOlinA-FernÁnDeZ FreDeric GArDes cOsimO lAcAVA periKlis petrOpOUlOs Optoelectronics research centre University of SouthamptonSouthampton SO171BJUK electrical Computer and Biomedical Engineering DepartmentUniversity of PaviaPavia 27100Italy telecommunication research institute(telmA) Universidad de MálagaCEI Andalucı´a TECHE.T.S.I.Telecomunicación29010 MálagaSpain school of science and technology Nottingham Trent UniversityNottingham NG118NSUK Department of electrical engineering Eindhoven University of TechnologyEindhoven 5600 MBThe Netherlands Department of materials science and engineering University of IoanninaIoannina 45110Greece centre de nanosciences et de nanotechnologies UniversitéParis-SaclayCNRS91120 PalaiseauFrance Advanced electronics and photonics research center National Research Council CanadaOttawaOntario K1A 0R6Canada

intermodal four-wave mixing(FWm)processes have recently attracted significant interest for all-optical signal processing applications thanks to the possibility to control the propagation properties of waves exciting distinct spatial modes of the same *** allows,in principle,to place signals in different spectral regions and satisfy the phase matching condition over considerably larger bandwidths compared to intramodal ***,the demonstrations reported so far have shown a limited bandwidth and suffered from the lack of on-chip components designed for broadband manipulation of different *** demonstrate here a silicon-rich silicon nitride wavelength converter based on Bragg scattering intermodal FWm,which integrates mode conversion,multiplexing and de-multiplexing functionalities *** system enables wavelength conversion between pump waves and a signal located in different telecommunication bands(separated by 60 nm)with a 3 dB bandwidth exceeding 70 nm,which represents,to our knowledge,the widest bandwidth ever achieved in an intermodal FWm-based system.

关键词： scattering pump modal

performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 teV with the AtlAs detector

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chinese physics c 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling n.J. Abicht s.h. Abidi A. Aboulhorma h. Abramowicz h. Abreu Y. Abulaiti B.s. Acharya c. Adam Bourdarios l. Adamczyk s.V. Addepalli m.J. Addison J. Adelman A. Adiguzel t. Adye A.A. Affolder Y. Afik m.n. Agaras J. Agarwala A. Aggarwal c. Agheorghiesei A. Ahmad F. Ahmadov W.s. Ahmed s. Ahuja X. Ai G. Aielli A. Aikot m. Ait tamlihat B. Aitbenchikh i. Aizenberg m. Akbiyik t.p.A. Åkesson A.V. Akimov D. Akiyama n.n. Akolkar K. Al Khoury G.l. Alberghi J. Albert p. Albicocco G.l. Albouy s. Alderweireldt m. Aleksa i.n. Aleksandrov c. Alexa t. Alexopoulos F. Alfonsi m. Algren m. Alhroob B. Ali h.m.J. Ali s. Ali s.W. Alibocus m. Aliev G. Alimonti W. Alkakhi c. Allaire B.m.m. Allbrooke J.F. Allen c.A. Allendes Flores p.p. Allport A. Aloisio F. Alonso c. Alpigiani m. Alvarez estevez A. Alvarez Fernandez m. Alves cardoso m.G. Alviggi m. Aly Y. Amaral coutinho A. Ambler c. Amelung m. Amerl c.G. Ames D. Amidei s.p. Amor Dos santos K.r. Amos V. Ananiev c. Anastopoulos t. Andeen J.K. Anders s.Y. Andrean A. Andreazza s. Angelidakis A. Angerami A.V. Anisenkov A. Annovi c. Antel m.t. Anthony e. Antipov m. Antonelli F. Anulli m. Aoki t. Aoki J.A. Aparisi pozo m.A. Aparo l. Aperio Bella c. Appelt A. Apyan n. Aranzabal s.J. Arbiol Val c. Arcangeletti A.t.h. Arce e. Arena J-F. Arguin s. Argyropoulos J.-h. Arling O. Arnaez h. Arnold G. Artoni h. Asada K. Asai s. Asai n.A. Asbah J. Assahsah K. Assamagan r. Astalos s. Atashi r.J. Atkin m. Atkinson h. Atmani p.A. Atmasiddha K. Augsten s. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal h. Bachacou K. Bachas A. Bachiu F. Backman A. Badea p. Bagnaia m. Bahmani A.J. Bailey V.r. Bailey J.t. Baines l. Baines O.K. Baker e. Bakos D. Bakshi Gupta V. Balakrishnan r. Balasubramanian e.m. Baldin p. Balek e. Ballabene F. Balli l.m. Baltes W.K. Balunas J. Balz e. Banas m. Bandieramonte A. Bandyopadhyay s. Bansal l. Barak m. Barakat e.l. Barberio D. Barberis m. Barbero m.Z. Barel K.n. Barends t. Barillari m-s. Barisits t. Barklow p. Baron D.A. Baron mo the AtlAs collaboration

the identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the large hadron collider,as standard model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the AtlAs collaboration,using √s=13 teV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the AtlAs *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 teV and for multiple tagger working points.

关键词： AtlAs Jet QUArK GlUOn tAGGinG

evidence of a J/ψΛstructure and observation of excited■^(-)states in the■b^(-)→J/ψΛK^(-) decay

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science Bulletin 2021年第13期66卷 1278-1287,M0003页

作者： r.Aaij c.Abellán Beteta t.Ackernley B.Adeva m.Adinolfi h.Afsharnia c.A.Aidala s.Aiola Z.Ajaltouni s.Akar J.Albrecht F.Alessio m.Alexander A.Alfonso Albero Z.Aliouche G.Alkhazov p.Alvarez cartelle s.Amato Y.Amhis l.An l.Anderlini A.Andreianov m.Andreotti F.Archilli A.Artamonov m.Artuso K.Arzymatov e.Aslanides m.Atzeni B.Audurier s.Bachmann m.Bachmayer J.J.Back s.Baker p.Baladron rodriguez V.Balagura W.Baldini J.Baptista leite r.J.Barlow s.Barsuk W.Barter m.Bartolini F.Baryshnikov J.m.Basels G.Bassi B.Batsukh A.Battig A.Bay m.Becker F.Bedeschi i.Bediaga A.Beiter V.Belavin s.Belin V.Bellee K.Belous i.Belov i.Belyaev G.Bencivenni e.Ben-haim A.Berezhnoy *** D.Berninghoff h.c.Bernstein c.Bertella e.Bertholet A.Bertolin c.Betancourt F.Betti ia.Bezshyiko s.Bhasin J.Bhom l.Bian m.s.Bieker s.Bifani p.Billoir m.Birch F.c.r.Bishop A.Bizzeti m.Bj┆rn m.p.Blago t.Blake F.Blanc s.Blusk D.Bobulska J.A.Boelhauve O.Boente Garcia t.Boettcher A.Boldyrev A.Bondar n.Bondar s.Borghi m.Borisyak m.Borsato J.t.Borsuk s.A.Bouchiba t.J.V.Bowcock A.Boyer c.Bozzi m.J.Bradley s.Braun A.Brea rodriguez m.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu A.Buonaura c.Burr A.Bursche A.Butkevich J.s.Butter J.Buytaert W.Byczynski s.cadeddu h.cai r.calabrese l.calefice l.calero Diaz s.cali r.calladine m.calvi m.calvo Gomez p.camargo magalhaes A.camboni p.campana A.F.campoverde Quezada s.capelli l.capriotti A.carbone G.carboni r.cardinale A.cardini i.carli p.carniti l.carus K.carvalho Akiba A.casais Vidal G.casse m.cattaneo G.cavallero s.celani J.cerasoli A.J.chadwick m.G.chapman m.charles ph.charpentier G.chatzikonstantinidis c.A.chavez Barajas m.chefdeville c.chen s.chen A.chernov s.-G.chitic V.chobanova s.cholak m.chrzaszcz A.chubykin V.chulikov p.ciambrone m.F.cicala X.cid Vidal G.ciezarek p.e.l.clarke m.clemencic h.V.cliff J.closier J.l.cobbledick V.coco J.A.B.coelho J.cogan e.cogneras l.cojocariu p.collins t.colombo l.congedo A.contu n.cooke G.coombs G.corti c.m.costa sobral B.couturier D.c.craik J.crkovská m.cruz torres r.currie c.l.Da silva e.Dall’ centro Brasileiro de pesquisas Físicas(cBpF) Rio de JaneiroBrazil Universidade Federal do rio de Janeiro(UFrJ) Rio de JaneiroBrazil center for high energy physics Tsinghua UniversityBeijingChina school of physics state Key laboratory of nuclear physics and technology Peking UniversityBeijingChina University of chinese Academy of sciences BeijingChina institute Of high energy physics(ihep) BeijingChina institute of particle physics Central China Normal UniversityWuhanHubeiChina Univ.Grenoble Alpes Univ.Savoie Mont BlancCNRSIN2P3-LAPPAnnecyFrance Universitéclermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix marseille Univ CNRS/IN2P3CPPMMarseilleFrance Universitéparis-saclay CNRS/IN2P3IJCLabOrsayFrance laboratoire leprince-ringuet(llr) PalaiseauFrance lpnhe Sorbonne UniversitéParis Diderot Sorbonne Paris CitéCNRS/IN2P3ParisFrance i.physikalisches institut RWTH Aachen UniversityAachenGermany Fakultät physik Technische Universität DortmundDortmundGermany max-planck-institut für Kernphysik(mpiK) HeidelbergGermany physikalisches institut Ruprecht-Karls-Universität HeidelbergHeidelbergGermany school of physics University College DublinDublinIreland inFn sezione di Bari BariItaly inFn sezione di Bologna BolognaItaly inFn sezione di Ferrara FerraraItaly inFn sezione di Firenze FirenzeItaly inFn laboratori nazionali di Frascati FrascatiItaly inFn sezione di Genova GenovaItaly inFn sezione di milano-Bicocca MilanoItaly inFn sezione di milano MilanoItaly inFn sezione di cagliari MonserratoItaly Universita degli studi di padova Universita e INFNPadovaPadovaItaly inFn sezione di pisa PisaItaly inFn sezione di roma tor Vergata RomaItaly inFn sezione di roma la sapienza RomaItaly nikhef national institute for subatomic physics AmsterdamNetherlands nikhef national institute for subatomic physics and VU University Amsterdam AmsterdamNetherlands henryk niewodniczanski institute of nuclear physics polish Academy of sciences KrakówPoland AGh-University of science and techno

First evidence of a structure in the J/ψΛinvariant mass distribution is obtained from an amplitude analysis of■b^(-)J/ψΛK^(-)*** observed structure is consistent with being due to a charmonium pentaquark with strangeness with a significance of 3.1r including systematic uncertainties and lookelsewhere *** mass and width are determined to be 4458:8±2:9t4:7-1:1 meV and 17:3±6:5t8:0-5:7 meV,respectively,where the quoted uncertainties are statistical and *** structure is also consistent with being due to two *** addition,the narrow excited■^(-)states,n■(1690)and■(1820),are seen for the first time in a■b^(-)decay,and their masses and widths are measured with improved *** analysis is performed using pp collision data corresponding to a total integrated luminosity of 9 fb^(-1),collected with the lhcb experiment at centre-of-mass energies of 7,8 and 13 teV.

关键词： QcD exotics pentaquark spectroscopy Quarkonium particle and resonance production

the microsatellite polymorphism of heme oxygenase-1 is associated with baseline plasma il-6 level but not with restenosis after coronary in-stenting

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chinese medical Journal 2005年第18期118卷 1525-1532页

作者： li ping mohamed A. elrayess Abuzeid h. Gomma Jutta palmen emma hawe Kim m. fox steve e. humphries cardiovascular Department Second Affiliated Hospital of JiangxiMedical College Nanchang 330006 China centre for cardiovascular Genetics British Heart FoundationLaboratories Department of Medicine Rayne Building 5 UniversityStreet London WC1E 6JF national heart ＆ lung institute and royal Brompton hospital Cardiac Medicine Sydney Street London SW3 6NP

Background Vascular smooth muscle cells （Vsmcs） can express heme-oxygenase （hO）, a rate-limiting enzyme in the degradation of heme to bilirubin, ferritin and carbon monoxide （ cO）. Vsmc-derived cO can suppress Vsmc proliferation and may serve as an antiproliferation factor. the promoter region of hO-1 shows a polymorphism with different （Gt）n repeats that has been reported to differently induce gene expression. the objective of this study was to examine the effect of this variation on the occurrence of restenosis after in-stent treatment in patients with coronary artery disease. methods candidates who underwent coronary stent implantation were genotyped for the hO-1 promoter polymorphism using polymerase chain reaction （pcr） and automated DnA capillary sequencer. serum levels of il-6 and c-reactive protein （crp） were obtained at baseline, 24 hours and 48 hours after stenting. the primary end point for the study was angiographic evidence of in-stent restenosis at 6 months. All parameters for evaluation of restenosis were analysed by quantitatve computer-assisted angiographic analysis （QcA）. results One hundred and eighty-seven patients who underwent coronary stent implantation were studied of whom 27.8% showed 〉150% restenosis after 6 months. the distribution of （Gt）n repeats of all patients in the promoter region of hO-1 genotype ranged from 22 to 42, with （Gt） 25 and （Gt） 32 being the two most common alleles. the allelic repeats were divided into the short class （s） with 29 （ Gt）., the middle class （m） with 30- 37 （Gt）n and the long class （l） with 38 （Gt）n. there was no significant difference in the restenosis between the genotype groups or between post operation levels of inflammation markers, but carriers of the s allele （ n = 120） had 33.3% lower baseline il-6 compared with non-s carriers （n =67, p =0. 0008）. conclusions Although no association was observed between the hO-1 promoter polymorphism and coronary in-stent restenosis following the stent procedure, the

关键词： heme oxygenase·polymorphism·interleukin-6·c- reactive protein·restenosis

search for the rare decay B^(0)→J/ψФ

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chinese physics c 2021年第4期45卷 47-60页

作者： r.Aaij c.Abellin Beteta t.Ackernley B.Adeva m.Adinolfi h.Afsharnial c.A.Aidala s.Aiola Z.Ajaltouni s.Akar J.Albrecht F.Alessio m.Alexander A.Alfonso Albero Z.Aliouche G.Alkhazov p.Alvarez cartelle s.Amato Y.Amhis l.An l.Anderlini A.Andreianov m.Andreotti F.Archilli A.Artamonov m.Artuso K.Arzymatov e.Aslanides m.Atzeni B.Audurier s.Bachmann m.Bachmaver J.J.Back s.Baker p.Baladron rodriguez V.Balagura W.Baldinit J.Baptista leite r.J.Barlow s.Barsuk W.Barter m.Bartolini F.Baryshnikov J.m.Basels G.Bassi B.Batsukh A.Battig A.Bay m.Becker F.Bedeschis i.Bediaga A.Beiter V.Belavin s.Belin V.Bellee K.Belous i.Belov i.Belyaev G.Bencivenni e.Ben-haim A.Berezhnoy *** D.Berninghoff h.c.Bernstein c.Bertella e.Bertholet A.Bertolin c.Betancourt F.Betti m.O.Bettler ia.Bezshyiko s.Bhasin J.Bhom l.Bian m.s.Bieker s.Bifani p.Billoir m.Birch F.c.r.Bishop A.Bizzeti m.Biorn m.p.Blago t.Blake F.Blanc s.Blusk D.Bobulska J.A.Boelhauve O.Boente Garcia t.Boettcher A.Boldyrev A.Bondar n.Bondar s.Borghi m.Borisyak m.Borsato J.t.Borsuk s.A.Bouchiba t.J.V.Bowcock A.Boyer c.Bozzi m.J.Bradley s.Braun A.Brea rodriguezs m.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu A.Buonaura c.Burr A.Burschee A.Butkevich J.s.Butter J.Buytaert W.Byczynski s.cadeddu h.cai r.calabrese l.calefice l.calero Diaz s.cali r.calladine m.calvi m.calvo Gomez p.camargo magalhaes A.camboni p.campana D.h.campora perez A.F.campoverde Quezada s.capelli l.capriotti A.carbonel G.carboni r.cardinale A.cardini i.carli p.carniti l.carus K.carvalho Akiba A.casais Vidal G.casse m.cattaneo G.cavallero s.celani J.cerasoli A.J.chadwick m.G.chapman m.charles ph.charpentier G.chatzikonstantinidis c.A.chavez Barajas m.chefdeville c.chen s.chen A.chernov s.-G.chitic V.chobanova s.cholak m.chrzaszcz A.chubykin V.chulikov p.ciambrone m.F.cicala X.cid Vidal G.ciezarek p.e.l.clarke m.clemencic h.V.cliff J.closier J.l.cobbledick V.coco J.A.B.coelho J.cogan e.cogneras l.cojocariu p.collins t.colombo l.congedo A.contu n.cooke G.coombs G.corti c.m.costa sobral B.couturier D.c.craik J.crkovska m.cruz centro Brasileiro de pesquisas Fisicas(cBpF) Riode JaneiroBrazil Universidade Federal do riode Janeiro(UFrJ) Riode JaneiroBrazil center for high energy physics Tsinghua UniversityBeijingChina school of physics state Key laboratory of nuclear physics and technology Peking UniversityBeijingChina University of chinese Academy of sciences BeijingChina institute Of high energy physics(ihep) BejingChina institute of particle physics Central China Normal UniversityWuhanHubeiChina Univ.Grenoble Alpes Univ.Savoie Mont BlancCNRSIN2P3-LAPPAnnecyFrance Universite clermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix marseille Univ CNRS/IN2P3CPPMMarseilleFrance Universitq paris-saclay CNRS/IN2P3IJCLabOrsayFrance lpnhe Sorbonne UniversiteParis Diderot Sorbonne Paris CiteCNRS/IN2P3ParisFrance i.physikalisches institut RWTH Aachen UniversityAachenGermany Fakultat physik Technische Universitat DortmundDortmundGermany max-planck-institut fir Kernphysik(mpiK) HeidelbergGermany physikalisches institut Ruprecht-Karls-Universitat HeidelbergHeidelbergGermany school of physics University College DublinDublinIreland inFn sezione di Bari BariItaly inFn sezione di Bologna BolognaItaly inFn sezione di Ferrara FerraraItaly inFn sezione di Firenze FirenzeItaly inFn laboratori nazionali di Frascati Frascatiltaly inFn sezione di Genova GenovaItaly inFn sezione di milano Bicocca Milanolaly inFn sezione di milano MilanoItaly inFn sezione di cagliari Monserratoltaly Universita degli studi di padova Universita e INFNPadovaPadovaItaly inFn sezione di pisa PisaItaly inFn sezione di roma tor Vergata RomaItaly inFn sezione di roma la sapienza RomaItaly nikhef national institute for subatomic physics AmsterdamNetherlands nikhef national institute for subatomic physics and VU University Amsterdam AmsterdamNetherlands henryk niewodniczanski institute of nuclear physics polish Academy of sciences KrakowPoland AGh-University of science and technology Faculty of Physics and Applied Computer Science

A search for the rare decay B^(0)→J/ψФis performed using pp collision data collected with the lhcb dete-ctor at centre-of-mass energies of 7,8 and 13 teV,corresponding to an integrated luminosity of9 *** significant signal of the decay is observed and an upper limitof 1.1x 10^(-7)at 90%confidence level is set on the branching fraction.

关键词： B physics flavour physics rare decay ω-Фmixing branching fraction

血红素氧化酶基因启动子Gt序列变化与冠状动脉支架术后再狭窄

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中国循环杂志 2006年第2期21卷 113-116页

作者：李萍 mohamedA.elrayess Abuzeidh.Gomma Juttapalmen emmahawe Kimm.fox stevee.humphries 南昌大学第二附属医院心内科江西省南昌市330006 centreforcardiovascularGeneticsBhFlaboratories UniversityCollegeLondon heartandlunginstituteandroyalBromptonhospital

目的:观察i型血红素氧化酶(hO-1)基因启动子Gt重复长短对冠状动脉支架置入术后再狭窄的影响。方法:187例行冠状动脉支架置入术者,6个月时随访再狭窄情况。pcr和DnA测序仪确定hO-1启动子Gt重复次数。高敏法测术前及术后24h、48h血浆白介... 详细信息

目的:观察i型血红素氧化酶(hO-1)基因启动子Gt重复长短对冠状动脉支架置入术后再狭窄的影响。方法:187例行冠状动脉支架置入术者,6个月时随访再狭窄情况。pcr和DnA测序仪确定hO-1启动子Gt重复次数。高敏法测术前及术后24h、48h血浆白介素-6(il-6)和c反应蛋白(crp)值。结果:各基因型间术后il-6和crp水平及再狭窄发生率无差异,携较短Gt者术前血浆il-6水平比非短Gt序列携带者低约33．3％(p=0．0008)。结论:hO-1基因多态性不影响支架置入术后炎症介质水平及再狭窄,但可能影响动脉粥样硬化形成的炎症过程。

关键词：血红素氧化酶 Gt重复序列再狭窄

利用自动照相术获得天山雪豹拍摄率与个体数量

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动物学报 2006年第4期52卷 788-793页

作者：马鸣徐峰 r. s. chUnDAWAt Kubanych JUmABAY 吴逸群艾则孜朱玛洪31.2.internationalsnowleopardtrust seattle WA98103 UsA34. 中国科学院新疆生态与地理研究所 international snow leopard trust SeattleWA98103USA 新疆托木尔峰自然保护区管理局

采用红外线自动照相机记录雪豹的活动和个体数量,这在国内尚属首次。野外调查开始于2005年10月18日,至12月27日结束。累计野外工作71d,共布设36台红外照相机,约2094个照相日,50256h,收回胶卷71个。在新疆天山托木尔峰自然保护区内5个峡... 详细信息

采用红外线自动照相机记录雪豹的活动和个体数量,这在国内尚属首次。野外调查开始于2005年10月18日,至12月27日结束。累计野外工作71d,共布设36台红外照相机,约2094个照相日,50256h,收回胶卷71个。在新疆天山托木尔峰自然保护区内5个峡谷的16个地点成功拍摄到清晰雪豹照片约32张,平均拍摄率或“捕获率”达1.53%。根据照片个体斑纹分析和“雪后痕迹调查”(signsurveyAftersnowing)的信息,确定在250km2范围内有5-8只雪豹活动,个体的日活动距离3-10km/d,其最低分布密度为2.0-3.2只/100km2。还拍摄到其它野生动物照片22张,如北山羊、野猪、草兔、石鸡、赤狐等。另外,还调查样线20条,搜集粪样和毛发样品计31个。

关键词：雪豹红外自动相机拍摄率种群密度雪后调查法天山

search for the doubly heavy baryons Ω^(0)_(bc) and e^(0)_(bc) decaying to Λ^(+)_(c)π^(-) and e^(+)_(c)π^(-)

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chinese physics c 2021年第9期45卷 10-21页

作者： r.Aaij c.Abelian Beteta t.Ackernley B.Adeva m.Adinolfi h.Afshamia c.A.Aidala s.Aiola Z.Ajaltouni s.Aka J.Albrecht F.Alessio m.Alexander A.Alfonso Albero Z.Aliouche G.Alkhazov p.Alvarez cartelie s.Amato Y.Amhis l.An l.Anderlini A.Andreianov m.Andreotti F.Archilli A.Artamonov m.Artuso K.Arzymatov e.Aslanides m.Atzeni B.Audurier s.Bachmann m.Bachmayer J.J.Back p.Baladron rodriguez V.Balagura W.Baldini J.Baptista leite r.J.Barlow s.Barsuk W.Barter m.Bartolini F.Baryshnikov J.m.Basels G.Bassi B.Batsukh A.Battig A.Bay m.Becker F.Bedeschi i.Bediaga A.Beiter V.Belavin s.Belin V.Bellee K.Belous i.Belov i.Belyaev G.Bencivenni e.Ben-haim A.Berezhnoy *** D.Beminghoff h.c.Bernstein c.Bertella A.Bertolin c.Betancourt F.Betti ia.Bezshyiko s.Bhasin J.Bhom l.Bian m.s.Bieker s.Bifani p.Billoir m.Birch F.c.r.Bishop A.Bitadze A.Bizzeti m.Bjorn m.p.Blago t.Blake F.Blanc s.Blusk D.Bobulska J.A.Boelhauve O.Boente Garcia t.Boettcher A.Boldyrev A.Bondar n.Bondar s.Borghi m.Borisyak m.Borsato J.t.Borsuk s.A.Bouchiba t.J.V.Bowcock A.Boyer c.Bozzi m J.Bradley s.Braun A.Brea rodriguez m.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu A.Buonaura c.Burr A.Bursche A.Butkevich J.s.Butter J.Buytaert W.Byczynski s.cadeddu h.cai r.calabrese l.calefice l.calero Diaz s.cali r.calladine m.calvi m.calvo Gomez p.camargo magalhaes A.camboni p.campana A.F.campoverde Quezada s.capelli l.capriotti A.carbone G.carboni r.cardinale A.cardini i.carli p.camiti l.carus K.carvalho Akiba A.casais Vidal G.casse m.cattaneo G.cavallero s.celani J.cerasoli A.J.chadwick m.G.chapman m.charles ph.charpentier G.chatzikonstantinidis c.A.chavez Barajas m.chefdeville c.chen s.chen A.chernov V.chobanova s.cholak m.chrzaszcz A.chubykin V.chulikov p.ciambrone m.F.cicala X.cid Vidal G.ciezarek p.e.l.clarke m.clemencic h.V.cliff J.closier J.l.cobbledick V.coco J.A.B.coelho J.cogan e.cogneras l.cojocariu p.collins t.colombo l.congedo A.contu n.cooke G.coombs G.corti c.m.costa sobral B.couturier D.c.craik J.crkovska m.cruz torres r.currie c.l.Da silva e.Dall'Occo J.Dalseno c.D'Ambrosi centro Brasileiro de pesquisas Fisicas(cBpF) Rio de JaneiroBrazil Universidade Federal do rio de Janeiro(UFrJ) Rio de JaneiroBrazil center for high energy physics Tsinghua UniversityBeijingChina institute of high energy physics(ihep) BeijingChina school of physics state Key laboratory of nuclear physics and technology Peking UniversityBeijingChina University ofchinese Academy of sciences BeijingChina institute of particle physics Central China Normal UniversityWuhanHubeiChina Univ.savoie mont Blanc CNRSIN2P3-LAPPAnnecyFrance Universite clermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix marseille Univ CNRS/IN2P3CPPMMarseilleFrance Universite paris-saclay CNRS/IN2P3IJCLabOrsayFrance laboratoire leprince-ringuet CNRS/IN2P3Ecole PolytechniqueInstitut Polytechnique de ParisPalaiseauFrance lpnhe Sorbonne UniversiteParis Diderot Sorbonne Paris CiteCNRS/FN2P3ParisFrance i.physikalisches institut RWTH Aachen UniversityAachenGermany Fakultat physik Technische Universitat DortmundDortmundGermany max-planck-institut für Kemphysik(mpiK) HeidelbergGermany physikalisches institut Ruprecht-Karls-Universitat HeidelbergHeidelbergGermany school of physics University College DublinDublinIreland inFn sezione di Bari BariItaly inFn sezione di Bologna BolognaItaly inFn sezione di Ferrara FerraraItaly inFn sezione di Firenze FirenzeItaly inFn laboratori nazionali di Frascati FrascatiItaly inFn sezione di Genova GenovaItaly inFn sezione di milano MilanoItaly inFn sezione di milano-Bicocca MilanoItaly inFn sezione di cagliari MonserratoItaly Universita degli studi di padova Universita e INFNPadovaPadovaItaly inFn sezione di pisa PisaItaly inFn sezione di roma la sapienza RomaItaly inFn sezione di roma tor Vergata RomaItaly nikhef national institute for subatomic physics AmsterdamNetherlands nikhef national institute for subatomic physics and VU University Amsterdam AmsterdamNetherlands AGh-University of science and technology Faculty of Physics and Applied Computer ScienceKr

the first search for the doubly heavyΩ^(0)_(bc)baryon and a search for the e^(0)_(bc)baryon are performed using pp collision data collected via the lhcb experiment from 2016 to 2018 at a centre-of-mass energy of 13 teV,corresponding to an integrated luminosity of 5.2 fb^(-1).the baryons are reconstructed via their decays to Λ^(+)_(c)π^(-)and e^(+)_(c)π^(-).no significant excess is fbund for invariant masses between 6700 and 7300 meV/c^(2),in a rapidity range from 2.0 to 4.5 and a transverse momentum range from 2 to 20 meV/*** limits are set on the ratio of the Ω^(0)_(bc)and e^(0)_(bc)production cross-section times the branching fraction to Λ^(+)_(c)π^(-)(e^(+)_(c)π^(-))relative to that of the Λ^(0)_(b)(e^(0)_(b))baryon,for different lifetime hypotheses,at 95%confidence *** upper limits range from 0.5 x 10^(-4)to 2.5 x 10^(-4)for theΩ^(0)_(bc)→Λ^(+)_(c)π^(-)(e^(0)_(bc)→Λ^(+)_(c)π^(-))decay,and from 1.4x 10^(-3)to 6.9 x 10^(-3)for theΩ^(0)_(bc)→e^(+)_(c)π^(-)(e^(0)_(bc)→e^(+)_(c)π^(-))decay,depending on the considered mass and lifetime of theΩ^(0)_(bc)(e^(0)_(bc))baryon.

关键词： B physics quarkonium spectroscopy heavy quark production

histone h3.3G34-mutant interneuron progenitors co-opt pDGFrA for Gliomagenesis

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四川生理科学杂志 2020年第4期42卷 480-480页

作者： carol c l chen Department of human Genetics McGill University Montreal QC H3A 0C7 Canada canadian centre for computational Genomics McGill University Montreal QC H3A 0E9 Canada Dana-Farber/Boston children’s cancer and Blood Disorders center Boston MA 02215 USA Department of pathology Montreal Children’s Hospital McGill University Health Centre Montreal QC H4A 3J1 Canada Ucl Queen square institute of neurology London WC1N 3BG UK Department of pediatrics McGill University and The Research Institute of the McGill University Health Centre Montreal QC H4A 3J1 Canada samantha Dickson Brain cancer Unit University College London Cancer Institute London United Kingdom second Department of paediatrics Semmelweis University Budapest 1094 Hungary Department of neurosurgery University of Debrecen Debrecen 4032 Hungary Department of paediatric haematology and Oncology Second Faculty of Medicine Charles University and University Hospital Motol Prague 150 06 Czech Republic Department of pathology and molecular medicine Second Faculty of Medicine Charles University and University Hospital Motol Prague 150 06 Czech Republic children’s cancer center The Royal Children’s Hospital murdoch children’s research institute Department of pediatrics University of Melbourne Parkville VIC 3052 Australia Kids cancer centre Sydney Children’s Hospital Randwick NSW 2031 Australia Department of pathology Centre Hospitalier Universitaire Sainte-Justine Université de Montréal Montréal QC H3T 1C5 Canada Department of pediatric Oncology Dana-Farber Boston Children’s Cancer and Blood Disorders Center Boston MA 02215 USA school of computer science McGill University Montreal QC H3A 2A7 Canada and murdoch children’s research institute parkville VIC 3052 Australia Department of Biochemistry McGill University Montreal QC H3A 1A3 Canada Department of pediatric neurosurgery Centre Hospitalier Universitaire Sainte-Justine Université de Montréal Montréal QC H3T 1C5 Canada Department of Biochemistry and

histone h3.3 glycine 34 to arginine/valine(G34r/V)mutations drive deadly gliomas and show exquisite regional and temporal specificity,suggesting a developmental context permissive to their *** we show that 50%of G34r/V tumors(n=95)bear activating pDGFrA mutations that display strong selection pressure at *** considered gliomas,G34r/V tumors actually arise in GsX2/DlX-expressing interneuron progenitors,where G34r/V mutations impair neuronal *** lineage of origin may facilitate pDGFrA co-option through a chromatin loop connecting pDGFrA to GsX2 regulatory elements,promoting pDGFrA overexpression and *** the single-cell level,G34r/V tumors harbor dual neuronal/astroglial identity and lack oligodendroglial programs,actively repressed by GsX2/DlX-mediated cell fate specification.G34r/V may become dispensable for tumor maintenance,whereas mutant-pDGFrA is potently ***,our results open novel research avenues in deadly tumors.G34r/V gliomas are neuronal malignancies where interneuron progenitors are stalled in differentiation by G34r/V mutations and malignant gliogenesis is promoted by co-option of a potentially targetable pathway,pDGFrA signaling.

关键词： pDGFrA specificity connecting